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Kim, Hyeongmin,Lee, Taeheon,Park, WonCheoul,Lee, Jin Woo,Kim, Jaemin,Lee, Bo-Young,Ahn, Hyeonju,Moon, Sunjin,Cho, Seoae,Do, Kyoung-Tag,Kim, Heui-Soo,Lee, Hak-Kyo,Lee, Chang-Kyu,Kong, Hong-Sik,Yang, Yo Oxford University Press 2013 DNA research Vol.20 No.3
<P>The modern horse (<I>Equus caballus</I>) is the product of over 50 million yrs of evolution. The athletic abilities of the horse have been enhanced during the past 6000 yrs under domestication. Therefore, the horse serves as a valuable model to understand the physiology and molecular mechanisms of adaptive responses to exercise. The structure and function of skeletal muscle show remarkable plasticity to the physical and metabolic challenges following exercise. Here, we reveal an evolutionary layer of responsiveness to exercise-stress in the skeletal muscle of the racing horse. We analysed differentially expressed genes and their co-expression networks in a large-scale RNA-sequence dataset comparing expression before and after exercise. By estimating genome-wide <I>d</I><SUB>N</SUB>/<I>d</I><SUB>S</SUB> ratios using six mammalian genomes, and F<SUB>ST</SUB> and iHS using re-sequencing data derived from 20 horses, we were able to peel back the evolutionary layers of adaptations to exercise-stress in the horse. We found that the oldest and thickest layer (<I>d</I><SUB>N</SUB>/<I>d</I><SUB>S</SUB>) consists of system-wide tissue and organ adaptations. We further find that, during the period of horse domestication, the older layer (F<SUB>ST</SUB>) is mainly responsible for adaptations to inflammation and energy metabolism, and the most recent layer (iHS) for neurological system process, cell adhesion, and proteolysis.</P>
Kim Taeheon,Kumaresan Yogeenth,Cho Sung Jun,Lee Chang-Lyoul,이헌,Jung Gun Young 나노기술연구협의회 2016 Nano Convergence Vol.3 No.33
As metal nanostructures demonstrated extraordinary plasmon resonance, their optical characteristics have widely been investigated in photo-electronic applications. However, there has been no clear demonstration on the location effect of plasmonic metal layer within the photoanode on both optical characteristics and photovoltaic performances. In this research, the gold (Au) nano-islands (NIs) film was embedded at different positions within the TiO2 nanoparticulate photoanode in dye-sensitized solar cells (DSSC) to check the effect of plasmon resonance location on the device performance; at the top, in the middle, at the bottom of the TiO2 photoanode, and also at all the three positions. The Au NIs were fabricated by annealing a Au thin film at 550 °C. The DSSC having the Au NIs-embedded TiO2 photoanode exhibited an increase in short circuit currents (Jsc) and power conversion efficiency (PCE) owing to the plasmon resonance absorption. Thus, the PCE was increased from 5.92% (reference: only TiO2 photoanode) to 6.52% when the Au NIs film was solely positioned at the bottom, in the middle or at the top of TiO2 film. When the Au NIs films were placed at all the three positions, the Jsc was increased by 16% compared to the reference cell, and consequently the PCE was further increased to 7.01%.
Kim, Byoungjae,Jeong, Jonghwa,Mohanty, Aruna Kumar,Lee, Taeheon,Han, Sangmin,Heo, Jiwon,Jung, Ki-Suck,Kim, Jin-goo,Paik, Hyun-jong Elsevier 2017 Reactive & functional polymers Vol.120 No.-
<P><B>Abstract</B></P> <P>We synthesized poly(poly(ethylene glycol)methyl ether methacrylate)-<I>b</I>-poly(2-(dimethylamino)ethyl methacrylate) (p(PEGMA-<I>b</I>-DMAEMA)) by sequential addition of monomers and its quaternized products (p(PEGMA-<I>b</I>-(DMAEMA-<I>co</I>-QDMAEMA)) from the reaction with benzyl chloride for dispersion of copper phthalocyanine (CuPc). The structure of block copolymers was characterized by <SUP>1</SUP>H NMR and GPC analysis. The block copolymers were investigated for their dispersion performance of CuPc in propylene glycol monomethyl ether acetate. The dispersion states of CuPc by dispersants were studied using dynamic light scattering.</P>
Reanalysis of Ohno's hypothesis on conservation of the size of the X chromosome in mammals
Kim, Hyeongmin,Lee, Taeheon,Sung, Samsun,Lee, Changkyu,Kim, Heebal The Korean Society for Integrative Biology 2012 Animal cells and systems Vol.16 No.6
In 1964, Susumu Ohno, an evolutionary biologist, hypothesized that the size of X chromosome was conserved in mammalian evolution, and that this was based on chromosomal length. Today, unlike Ohno's method which was based on estimated lengths, we know the exact lengths of some mammalian sequences. The aim of this study was to reanalyze Ohno's hypothesis. In mammalian species, variation in the length of the X chromosome is greater than in the autosomes; however, this variation is not statistically significant. This means that differences in chromosomal length occur equally in the X chromosome and in the autosomes. Interspersed nuclear elements and genetic rearrangements were analyzed to maintain the same variance between the length of the X chromosome and the autosomes. The X chromosome contained fewer short interspersed elements (SINEs) (0.90 on average); however, it did contain more long interspersed elements (LINEs) than did autosomes (1.56 on average). An overall correlation of LINEs and SINEs with genetic rearrangements was observed; however, synteny breaks were more closely associated with LINEs in the autosomes, and with SINEs in the X chromosome. These results suggest that the chromosome-specific activities of LINEs and SINEs result in the same variance between the lengths of the X chromosome and the autosomes. This is based on the function of interspersed nuclear elements, such as LINEs, which can inactivate the X chromosome and the reliance of non-autonomous SINEs on LINEs for transposition.
김태헌(Kim, Taeheon),이원희(Lee, Won Hee),염준호(Yeom, Junho),한유경(Han, Youkyung) 한국측량학회 2019 한국측량학회 학술대회자료집 Vol.2019 No.4
위성영상은 영상 취득 시 발생하는 외부 환경적 요소에 의해 기하 및 방사오차가 발생하며, 이는 전처리과정을 통해 제거 할 수 있다. 전처리과정은 기하보정 및 방사보정으로 구분되며 개별적으로 수행되기 때문에 인력 및 시간 비용의 소모가 크다. 이에, 본 연구에서는 동시에 상대 기하 및 방사보정을 수행하는 방법론을 제시하고자 한다. 시기가 다른 두 고해상도 위성영상에 SURF(Speed-Up Robust Features)을 적용하여 특징점을 추출하였으며, 추출된 특징점간의 방사학적 특성을 고려하여 PIFs(Pseudo Invariant Features)를 선정하였다. 최종적으로 추출된 특징점을 이용하여 기하 및 방사보정을 수행한 결과 기하 및 방사오차가 제거된 것을 확인하였다.