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( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.
Sang-Min Shin,Jun-Gyu Son,Byung-Chul Yang,Nam-Young Kim,Jai-Hoon Woo,Moon-Cheol Shin,Ji-Hyun Yoo 한국수정란이식학회 2018 한국수정란이식학회 학술대회 Vol.2018 No.11
Purpose The Jeju black cattle are a type of traditional Korean native cattle with a characteristic black fur that covers the entire body. The Jeju black cattle are rare breed and designated as national natural monuments in 2013. It is necessary to improve reproductive techniques for the preservation and proliferation of Jeju black cattle. Methionine acts as a precursor amino acid for glutathione in protection of cells from oxidative damage, and plays a vital role in detoxification. Low sperm motility causes infertility because when sperm do not have progressive motility, it was unable to reach the ovum. The purpose on this study was to investigate whether intake of L-methionine improves sperm motility and fertility. Materials and Methods 6 Jeju black cattles over 10 years of age are raised in Subtropical Livestock Research Institute, National Institute of Animal Science, RDA. 6 Jeju black cattles was fed with L-methionine with 10g/day during 6 weeks. Semen of Jeju black cattle were collected by artificial vaginal technique. Collected sperm was diluted with AndroMed® extender and cryopreserved in 0.5 ml French straws. Fresh and freeze-thawed sperm viability and motility were evaluated by CASA. Results The viability and progressive motility of fresh spermatozoa(live spermatozoa means: from 74.41% to 80.22%, progressive motility means: from 80.60% to 95.40%) and freeze-thawed spermatozoa(live spermatozoa means: from 51.26% to 62.05%, progressive motility: from 29.68% to 45.44%) incresed after L-methionine ingestion. Conclusion The intake of L-methionine in genetically valuable cattle over 10 years of age seems to be useful for improving sperm function.
Sung Woo Cho,YeJin Kyung,Geun-Ho Park,Sun-Ran Cho,Byung-Ho Lee,Jeong-Oh Yang,Hyun Kyung Kim,Gil-Hah Kim 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.10
A combination using phosphine (PH3) and ethyl formate (EF) was performed to compensate for the disadventages (long exposure time and phytotoxicity) of a single substance. P. longisipinus was more susceptible to mixed phosphine and ethyl formate than P. orchidicola in 12 L dessicator. Mortality of mixed treatment was higher than aggregated mortalities that treated individually, so it indicated to have a synergic effect on each other. Ethyl formate was showed higher adsorption rate than phosphine on imported nursery plants and showed differences depending on the plant. P. longispinus and P. orchidicola was showed 100% mortality when phosphine and ethyl formate was treated as 1 g/m3 and 30 g/m3 for 4 hour in 0.5 m3 fumigation chamber and in 10 m3 container. Phytotoxicity was evaluated to mixture of phosphine and ethyl formate at 1 month after treatment.
Economic Effect of Local Feed Utilization in Korea
Byung Oh Lee,Jeong Hee Yang,Sang Youn Park,Byeong Soon Lee 국제문화기술진흥원 2018 International Journal of Advanced Culture Technolo Vol.6 No.4
Rice straw is the principal forage for Korean cattle. Limited supply of domestic forage forces Korea to depend on imported forage. Utilizing locally available domestic feed as an alternative would lead to self-sufficiency and stability in cattle farm management. Locally available feed can be utilized as forage. The challenge of collecting local feed has been overcome by machines that have been developed to harvest feed. Local feed can be completely consumed in the production regions, thus reducing transportation costs and increasing price competitiveness. Hitherto, studies have focused on feed technologies and price competitiveness, among other factors, while the substitution of forage has not been examined. This study conducts a quantitative analysis to estimate the extent to which local feed can replace existing forage. We find that local feed is cheaper, and abundantly available, and can thus replace high-quality forage.
Effects of Knee Extensor Muscle Fatigue on Gait Ability in Patients with Chronic Stroke
Byung-Il Yang,Sang-Mi Joung 대한신경치료학회 2019 신경치료 Vol.23 No.1
Purpose The purpose of this study were how to effect gait ability to chronic stroke patients who were taken knee extensor fatigue and were understood and offered the way of effective therapy to stroke patients in clinical trials. Methods The subject of this study were 16 chronic stroke patients (9 males, 8 females), and 16 healthy volunteers(5 males, 11 females) and their average duration of symptoms were 4.9 years at S hospital in Sungnam city. Stroke patient group age was 55.67, health group age was 59.13. Both stroke patient group and healthy group were measured using maximal voluntary isometric contraction(MVIC) for leading knee extensor fatigue. Isometric contraction was maintained for 10 seconds. And each isometric contraction was taken rest 5 seconds one time for inducing muscle fatigue. The end point was measured decreasing 3 times continuously which the value of MVIC was less 50%, and then the number of knee extensor to induce muscle fatigue gait ability were measured after taking knee extensor fatigue. Results There was a significantly differences that Stroke patients group was shown that the paretic side knee extensor fatigue was represented faster than health control group (p<0.05). The gait ability were represented drastically decreased knee extensor fatigue in Stroke patients group’s non paretic side. Conclusion Therefore, localized muscle fatigue by gaiting abnormal gait pattern to chronic stroke patient was affected the disability of gait capacity. And abnormal gait pattern was brought secondly increasing number of falling down. These factors were considered to stroke rehabilitation.
Outcome of Transduo denal Surgical Ampullectomy for Ampullary Neopla는
( Yang Won Nah ),( Hyung Woo Park ),( Byeung Ju Kang ),( Byung Wook Lee ),( Sung Jo Bang ),( Hye Jung Choi ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Purpose: Adenomas arising from the ampulla of Vater (AoV) are premalignant lesions with risk for malignant transformation to carcinoma following the adenoma-to-carcinoma sequence. Accordingly, many experts advocate resection either endoscopically or surgically. However, excluding associated malignant disease prior to resection of an adenoma of the AoV is not always possible. And the procedure of choice to treat this rare tumor is still controversial among endoscopic papillectomy (EP), transduodenal surgical ampullectomy (TSA) and pancreatoduodenectomy (PD). With the introduction of EP recent years, TSA was regarded as a tool for unsuitable lesion for EP or after unsuccessful EP by some. In addition to this there might be a role of TSA for preinvasive early stage adenocarcinoma of AoV, substituting PD. This study was done to evaluate the outcomes of transduodenal surgical ampullectomy (TSA) of ampulla of Vater (AoV) neoplasm including adenoma as well as adenocarcinoma limited to the ampulla. Methods: 22 cases of AoV neoplasm treated by transduodenal surgical ampullectomy (TSA) during the period from 2010 to 2015 were reviewed retrospectively. Results: The patients were aged from 36 to 81 years (mean 56) and 12 were male. 11 patients were identified during routine health screening. The most frequent symptom was indigestion and noted in 4. Cholangitis and liver abscess was the initial presentation in one case each. Two cases were associated with familial adenomatous polyposis syndrome (FAP). Seven cases of TSA were performed after endoscopic papillectomy for unsuitability (2), inadequacy (2) or tumor recurrence (3). Preoperative endoscopic biopsy revealed adenoma in 11, low grade dysplasia (LGD) in 4, high grade dysplasia (HGD) in 5 and neuroendocrine tumor in 1. No case was diagnosed as adenocarcinoma on preoperative biopsy. Intraoperative frozen biopsy was done in 14 cases and revealed adenocarcinoma in 4 which were corresponding to adenoma in 2, LGD in 1 and HGD in 1 on preoperative biopsy. Two patients were converted to pylorus preserving PD according to the frozen biopsy result. Of TSA, 100 per cent had clear margins grossly and microscopically. Postoperative pathology revealed adenocarcinoma in 7 cases. All the adenocarcinomas were in their very early stage, reflected by carcinoma in situ in 2, invasion to lamina propria in 2, confined to mucosa in 1, confined to ampulla of Vater in 1 and focal adenocarcinoma of 2mm. There was no case of lymphovascular or perineural invasion. And those 2 cases who underwent PPPD revealed no lymph node metastasis. 5 patients with adenocarcinoma who underwent TSA showed no evidence of recurrence during follow period from 22 to 58 months. And all the 13 patients with adenoma, either with or without HGD showed no evidence of recurrence for 2 to 69 months. There were 3 complications after TSA including wound seroma in 1, voiding difficulty in 1 and T inversion on EKG in 1. Conclusion: Transduodenal surgical ampullectomy can be done safely with minimal morbidity while securing adequate safety margin for ampullary neoplasm. When the preoperative biopsy result of ampullary neoplasm does not tell adenocarcinoma definitely, TSA would be a good substitute for PD even though preoperative biopsy was not always correct in detecting adenocarcinoma. More study to define the detailed indication of TSA for adenocarcinoma of AoV is needed.
Sung-Chan Yang,Jegal Seung,Kim Myung-deok,Hyunwoo Kim,Bong Gu song,Byung-Eon Noh,Jong Yul Roh,Kyu Sik Chang,E-Hyun Shin,Young Ran Ju,Wook-Gyo Lee 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.10
We conducted a investigation for distribution and flavivirus infection of mosquitoes using black –light trap around Incheon international airport there was possible overseas inflow caused by global warming in Korea. Mosquitoes were collected once a week April to October during 6 years (2009~2015). The numbers of mosquitoes collected in Oseong and Eurwang mountain were 8,969 and 7,978 including 12 species 7 genera respectively during collecting period. Culex pipiens complex was dominant species in two collecting area as 4,621(51.5%) in Oseong and 3,761(47.1%) in Eurwang mountain. A total of 16 pools from 88 Aedes albopictus were performed a Dengue virus (DENV) detection and total 628 pools from 11,146 other mosquitoes performed a West nile virus (WNV) detection. Flavivirus was not detected during study period. This study may provide basic information for surveillance of imported diseases and vectors in Korea.