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( Jung Eum Lee ),( Youngsin Han ),( Suhyun Shim ),( Hyejin Hwang ),( Youn-jee Chung ),( Hyun-hee Cho ),( Mee-ran Kim ),( Mira Kim ),( Chai-young Jung ),( Kyung-hee Chae ),( Sukil Kim ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Objective: The purpose of this study examines myoma, adenomyosis and endometriosis epidemiology and treatment trend of the general population in Korea. Methods: This study is using the entire administrative data provided by the Korean National Health Insurance Service (NHIS) from 2002 to 2016. More than 50 million people signed up the KNHIS, so this data may represent most health care status of Korea. Diagnosis of myoma and adenomyosis is determined by ICD-10 code; D25 (D250~259) and N80.0. The ICD-10 defined the diagnosis code from N80.1 to N80.9 as endometriosis. The diagnosis code N80.0 (adenomyosis) is excluded, whereas N80 is included in the diagnosis. Results: Patients with diseases are increased throughout 15 years. The number of patients diagnosed with myoma and adenomyosis increased from 154,080 and 24,367 in 2002 to 557,547 and 128,794 in 2016, respectively. Also, 33,453 patients were diagnosed as endometriosis in 2002, 68,036 women have endometriosis in 2016. The prevalence of myoma, adenomyosis and endometriosis, between 11 to 52 year old ages, is increasing from 8.8, 1.4 and 1.9 per 1000 in 2002 to 28.8, 7.5 and 4.0 per 1000 in 2016, respectively. Treatment of these diseases was a mostly surgical approach, particularly hysterectomy is preferential treatment, but the ratio is decreasing. On the other hand, preserving the uterus and ovary method has increased recently. Conclusion: Epidemiology study of myoma, adenomyosis and endometriosis has done in various participants, so the prevalence and incidence have been suggested in wide range. This study is the first general population based epidemiologic study in Asia. Our study suggests prevalence and incidence of diseases has increased steadily. These diseases can influence fertility and quality of life of women, so screening and early detection of diseases is needed in reproductive aged women.
Intracellular protein delivery by glucose-coated polymeric beads
Jung, Suhyun,Huh, Seong,Cheon, Yong-Pil,Park, Seongsoon Royal Society of Chemistry 2009 Chemical communications Vol.2009 No.33
<P>Glucose-coated polymeric beads have been prepared and applied to delivery of a model protein (enhanced green fluorescent protein) into mouse embryonic stem cells as well as Hela cells.</P> <P>Graphic Abstract</P><P>Glucose can be used as a recognition molecule to establish an interaction with the cell membrane for intracellular protein delivery. Glucose-coated polymeric beads have shown the delivery of EGFP (enhanced green fluorescent protein) into mouse embryonic stem cells as well as Hela cells. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b906268h'> </P>
Bio-functionalization of metal–organic frameworks by covalent protein conjugation
Jung, Suhyun,Kim, Youngmee,Kim, Sung-Jin,Kwon, Tae-Hwan,Huh, Seong,Park, Seongsoon Royal Society of Chemistry 2011 Chemical communications Vol.47 No.10
<P>Bioconjugation of functional proteins onto metal–organic frameworks (MOFs) has been achieved using activation of pendent linking groups of the organic linkers on the surface of MOFs. Fluorescent microscopy revealed successful conjugation of an enhanced fluorescent protein onto MOFs. In addition, <I>Candida-antarctica</I>-lipase-B-conjugated MOFs showed no loss of enantioselectivity and activity in transesterification of (±)-1-phenylethanol.</P> <P>Graphic Abstract</P><P>Bioconjugation of functional proteins onto metal–organic frameworks (MOFs) has been achieved using activation of pendent linking groups of the organic linkers on the surface of MOFs. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0cc03288c'> </P>
Status and Needs of Continuing Education for Trauma Nursing
( Yooun-joong Jung ),( Suhyun Kim ),( Sangmi Noh ),( Eunkyoung Seo ),( Soyoung Jung ),( Jiyoung Kim ) 대한외상학회 2019 大韓外傷學會誌 Vol.32 No.3
Purpose: This study was conducted to status and needs for continuing education for trauma hospital nurses in Korea. Methods: Thirty nurses from the seven level I trauma center hospitals or trauma treatment systems were randomly selected and surveyed. The survey was conducted from March 1 to May 31, 2017. Categorical data were analyzed with Pearson chi-square tests and Continuous variables were analyzed with ANOVA. Results: Only 86 out of 204 nurses had received continuing education (42.1%). The current status of continuing education programs, delivering institution (p<0.001), education method (p<0.001), education period (p=0.003), number of participants (p=0.007), and instructors (p=0.014) were also significantly different from trauma center to trauma center. There were 108 (52.9%) nurses who responded that continuing education programs were “needed” 92 (45.1%) and “very much needed 16 (7.8%). According to each trauma center’s characteristics were significantly differences in the need for continuing education (p=0.089), subject selection method (p<0.001) and the number of continuing education sessions (p=0.043) depending on the hospital. Conclusions: It is necessary to consider differences between the hospitals to develop continuing education programs that reflect the needs of nurses, in order to improve the efficiency of and satisfaction with the educational programs.