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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재후보
      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • SCOPUSKCI등재
      • SUN Solaris 환경에서 시간 동시화 프로토콜의 구현

        배시규 동양대학교 1995 동양대학교 논문집 Vol.1 No.1

        We have proposed MASP(Multimedia Association Synchronization Protocol) to transmit multimedia data with temporal relationship on general networks not guaranteeing a constant delay time. This paper describes the implementation of the MASP to support the intra-media and inter-media synchronization for multimedia objects including continuous or discrete data.To implement the MASP we have represented the protocol using state transition table and completed the protocol's core module with a C-language.This module is fullfilled in a form of the driver within kernel using STREAMS mechanism in the SUN workstation with System V-based Solaris operating system.In addition, we also designed user interface and loopback driver.we tested MASP whether or not to work succesfully with our test program.The result is that the connection(and/or association) establishment/release functions work well and multimedia data such as video and audio can be delivered on time according to the target playout time.

      • 뇌실-복강단 단락수술에 의한 뇌수종 치료의 임상적 고찰

        송시헌 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

        The ventriculoperitoneal shunt(V-P shunt) has emerged as the preferred diversionary procedure for hydrocephalic patients with various underlying causes. Its major advantages are the relatively benign nature of complications, the ease of shunt placement and shunt revision. This study reviews 37 patients who had the V-P shunt at Chungnam National University Hospital. The major complications of the V-P shunt were infection(9.5%), shunt malfunction (9.5%), subdural hygroma(7.1%) and seizure(2.4%). Of the patients with V-P shunt 83.8% had good improvement. Also, computerized tomographic findings and the causes of underlying diseases were reviewed.

      • 돌발성 난청 임산부에서 발생한 폐부종

        김시찬 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        A 33-year-old woman was admitted to the hospital with a sudden onset of hearing loss in her right ear. Audiometry showed a sloping-type sensorinerural hearing loss with a pure-tone average of 95 dB in the right ear. Intravenous infusion of steroid, heparin and dextran were administered. The tachypnea and dyspnea developed 2 days later. A chest radiograph revealed pulmonary edema with bilateral perihilar infiltrates. After interruption of dextran, subsequent supportive treatment relieved chest symptoms without any sequelae. The treatment with dextran in the pregnant woman with sudden deafness should be cautiously performed.

      • 우리나라 鍾乳窟의 特性과 環境汚染에 關한 硏究

        洪始煥,朴冕用 건국대학교 1979 學術誌 Vol.23 No.2

        This paper reviews the general status of stalactite caves which were found and are utilized for sight-seeing in Korea, and also summarizes the results of investigations on properties of natural stalactite caves. The cavernous phenomena such as the water quality, atmospheric phenomena, secondary grown products, ecological adaptation, environmental pollution and the breakage of stalactite are compared between those of cave a which are opened already sight-seeing and unresults are discussed and also compared with the caves in other countries. Environmental pollutions in Korean stalactite caves are as the following : The animate matters in caves are disappeared gradually from the time of exposure for sight-seeing. The kinds and abundance of the animate matters favoring the cavernous life or coming from the outside of caves have relativity to temperature, moisture and atmospheric conditions in caves. The water quality is consistent throughout the entire flow passage in a cave, but calcium content were less with the increase of flowing water volume in a cave. Atmospheric phenomena at entrance of a cave show a slight difference from the inner atmosphere, and the moisture content in cavernous atmosphere are increased with the cave depth. The secondary growth of stalactite are not taken place at the entry, because of low moesture content in air. However, stalactite secondary growth were prominent at inner cave where the moisture content is more than 90%. The temperature variation in the caves are negligible through all seasones in a year. The following conditions are critical to conserve the cavernous environmental pollution and the original form of caves. Some caves should not be exposed to the sight-seeing for academic studies. If the caves are open for sight-seeing, the entrance should be restricted with an adequate to limit the changes of atmospheric phenomena. In rainy season, the surface water flowing outside of cave should be protected from entering into the caves and water pool should be drained out to outside of cave. Proper number of waste cans should be provided along the pathway in the caves.

      • 腦脊髓液壓의 臨床實驗的 硏究(Ⅰ)

        宋時憲 충남대학교 의과대학 지역사회의학연구소 1980 충남의대잡지 Vol.7 No.2

        Lumbar cerebrospinal fluid (CSF) pressure was recorded in 115 outpatients who were not associated with any change in intracranial pressure and without any special disease entities either: of whom 65 subjects (Group I) with a intermittent low back pain used a 18-gauge needle, while for the rest of 50 subjects with mild head trauma who came to the emergency room who used 22-gauge needle (Group II). The CSF pressure was measured in a position of an excessive spinal flexion and then an adequately relaxed spine with the lateral recumbent position maintained all the while. After that Queckenstedt test was performed. And then, CSF pressure recording was done after every 1 cc of CSF withdrawal until the withdrawal amounted to 5cc, the withdrawal rate being 1 cc/min. in both of the groups. In this study, the normal CSF pressure obtained (thus) was compared with undistorted normal physiolgic CSF pressure. The results obtained are as follows : 1. The average CSF pressure recorded under the condition of any possibility to cause any anxiety and tension was 152(±31) mm of CSF in group I and 159(±34)mm of CSF in group II . 2. In group I, for whom a 18-gauge needle was used, a lower value (152±31 mm of CSF) was obtained compared with the group II (159±34 mm of CSF) for whom a 22-gauge was used. 3. The CSF pressure recorded under condition of spinal hyperflexion(160±29 mm of CSF in group I and 184±34mm of CSF in group II) was slightly higher than that recored in comfortable, relaxed state (152±31 mm of CSF in group I and 159±34 mm of CSF in group II). 4. There was not any remarkable difference in CSF pressure above the age of 11. 5. The CSF pressure data obtained on CSF withdrawal amounitng to 5cc gave a linear pressure-volume curve and the amount of decreased pressure was 24 mm of CSF in group I and 21 mm of CSF in group II.

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