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CoNbZr/Cu/CoNbZr 다층박막의 습식 식각 거동에 관한 연구
윤재홍,김현식,송재성,이영생,민복기 國立 昌原大學校 産業技術硏究所 1997 産技硏論文集 Vol.11 No.-
We manufactured CNZ/Cu/CNZ multi-layers by sputtering methode and formed pattern on the deposited multi-layers. In this study, we fabricated new etchant for the etching to formed pattern by the wet chemical etchant. it was searching for the best condition of etchant. Cu was etched selectively independence in the concentration of basic solution but amorphous CNZ thin film did not. The etchant was achieved by basic solution(17.5 mol%) and HF(20mol%) mixing, which etched CNZ/Cu/CNZ multi-layers in the same. Also, the etchant etched CNZ/Cu/CNZ multi-layers by the three-step. It was shown that the etched cross-section have isotropic structure and excellent etching characteristics.
李允中,尹汝生,崔點洙,金在鉉 成均館大學校 科學技術硏究所 1989 論文集 Vol.40 No.2
Lincomycin is a new antibiotic produced by Streptomyces lincolensis var. lincolensis. It is active against Gram positive aerobes and very active against both Gram positive and negative anaerobic pathogens. The present study was conducted to optimize the analytical conditions of bioassay, GLC and HPLC to make them more sensitive and convenient methods for the routine quality control of the antibiotics. The results were as follows; 1. When Micrococcus Idea UC 1:30 replaced the conventially used microorganism, Sarcina lutea ATCC 9341, the zone reading time was more stable and the hydrolysis could be prevented. 2. GLC method could complete the analysis within 10 min. with higher reproducibility(coefficient of variation 1.65%) compared to that of bioassay. 3. HPLC method employing ion-pairing mechanism could complete the analysis within 15 min. with minimum peak tailing, and with higher precision(within ± 2%) compared to that of bioassay.
製劑中 Phenylpropanolamine Hydrochloride의 Dansyl 誘導體에 依한 螢光分析法 硏究
李允中,李康春,尹汝生,金在鉉,崔点洙 成均館大學校 1982 論文集 Vol.31 No.-
A simple, rapid and sensitive fluorometric assay for phenylpropanolamine hydrochloride was developed based on their interacion with I dimethylaminonaphthalene-5-sulfonylchloride(Dansyl chloride) in acetone to yield fluorescent compound, with excitation and emission wavelengths of 350 and 495 nm, respectively. A study of optimum pH, reaction time, temperature and dansyl chloride concentration is presented. Fluorescence is linear the range 1∼7μg phenylpropanolamine hydrochloride per ml of sample. The fluorescence was stable for at least 2 hours. Application of the procedure to the analysis of phenylpropanolamine hydrochloride in dosage forms gave an accuracy 1∼4%.
KIM, Kwang-Yul,LEE, Seung-Woo,HWANG, Yu-Min,LEE, Jae-Seang,KIM, Yong-Sin,KIM, Jin-Young,SHIN, Yoan 'Institute of Electronics, Information and Communi 2017 IEICE transactions on fundamentals of electronics, Vol.ea100 No.4
<P>A chirp spread spectrum (CSS) system uses a chirp signal which changes the instantaneous frequency according to time for spreading a transmission bandwidth. In the CSS system, the transmission performance can be simply improved by increasing the time-bandwidth product which is known as the processing gain. However, increasing the transmission bandwidth is limited because of the spectrum regulation. In this letter, we propose a correlation-based chirp rate allocation method to improve the transmission performance by analyzing the cross-correlation coefficient in the same time-bandwidth product. In order to analyze the transmission performance of the proposed method, we analytically derive the cross correlation coefficient according to the time-bandwidth separation product and simulate the transmission performance. The simulation results show that the proposed method can analytically allocate the optimal chirp rate and improve the transmission performance.</P>
Effect of Lycii cortex radicis Extraction on Glioma Cell Viability
Kim, Seang-Jae,Jeong, Ji-Cheon The Society of Korean Medicine 2009 대한한의학회지 Vol.30 No.6
Objectives: Little information is available regarding the effect of Lycii cortex radicis (LCR) on cell viability in glioma cells. This study was therefore undertaken to examine the effect of LCR on cell survival in U87MG human glioma cells. Methods: Cell viability and cell death were estimated by MTT assay and trypan blue exclusion assay, respectively. Reactive oxygen species (ROS) generation was measured using the fluorescence probe DCFH-DA. Activation of Akt and extracellular signal-regulated kinase (ERK) and activation of caspase-3 were estimated by Western blot analysis. Results: LCR resulted in apoptotic cell death in a dose- and time-dependent manner. LCR increased reactive oxygen species (ROS) generation and LCR-induced cell death was also prevented by antioxidants, suggesting that ROS generation played a critical role in LCR-induced cell death. Western blot analysis showed that LCR treatment caused down-regulation of Akt and ERK. The LCR-induced cell death was increased by the inhibitors of Akt and ERK. Activation of caspase-3 was stimulated by LCR and caspase inhibitors prevented the LCR-induced cell death. Conclusion: These findings suggest that LCR results in human glioma cell death through a mechanism involving ROS generation, down-regulation of Akt and ERK, and caspase activation.
김태형(Tae Hyoung Kim),이성주(Seang Ju Lee),김의태(Eui Tae kim),김창수(Chang Su Kim),황장순(Jang Sun Hwang),유상재(Sang Jae Yoo),김동성(Dong Seang Kim) 대한CT영상기술학회 2015 대한CT영상기술학회지 Vol.17 No.2
목적 : CT검사 시 발생할 수 있는 피검사자를 제외한 민원의 표면선량 및 흡수선량을 측정하여 수치화하여 불필요한 피폭을 최소화 할 수 있는 방법을 찾고자 하였다. 대상 및 방법 : 본원의 Somatom Sensation 16 MDCT장비를 사용하여 water phantom을 scan 하였고 거리와 보호 장비 착용유무에 변화를 두어 Atom팬텀의 흡수선량과 표면선량을 측정하였다. 결과 : 표면선량과 흡수선량 모두 방사선 보호 장비의 착용 및 거리에 따라 흡수율이 크게 감소됨을 알 수 있었다. 결론 : 피검사자외의 인원이 불가피하게 위치하여야 경우 gantry와의 거리를 2M이상으로 유지한 상태에서 기준에 맞는 방사선 보호 장구를 착용하였을 시 흡수선량이 큰 폭으로 감소함을 확인 할 수 있었다. 불가피한 의료 방사선의 피폭을 최소화 하기 위해 방사선 보호 장구의 착용은 필수적인 요소이며 거리에 따른 감소도 더욱 신경 써서 지켜야 할 필요가 있다. Purpose : To minimize an unnecessary radiation dose which might affects to medical staffs or patient guardians who stay aside a patient in a CT room. This study was evaluated by a metric of the effective dose and surface dose. Materials and Methods : This study was performed with a water phantom and anthropomorphic body phantom (Atom) using 16- channel MDCT (Somatom, Sensation, Siemens). The metrics were designed into two categories which one is a scan with protection equipment (Lead Apron) and the other is without the protection. Also, radiation doses were measured at various distances from X-ray exposure spot. Results: The absorption rate of the surface dose and absorbed dose were highly reduced with the protection equipment and over 1 meter from X-ray source spot. Also, the effective dose was reduced significantly. Conclusion : It is clear that the both absorbed and surface dose were reduced by the proper protection equipments (Lead Apron and Thyroid guard) and 2 meters distance from X-ray exposure spot. It is an essential factor that we have to provide the proper protection to medical staffs and the patient guidance to minimize unnecessary radiation dose.