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Suvarna Patil,Fakrudin Bashasab,Vijaykumar,Basavanagoud,Mahaling S Kuruvinashetti,Basavaraj V Patil 한국응용곤충학회 2006 Journal of Asia-Pacific Entomology Vol.9 No.3
The genetic relatedness among Helicoverpa armigera (Hübner) occurring on different host plants prevailing in South India was studied using PCR- RAPD. Genomic DNA was isolated individually from five larvae collected from each of 10 different host plants (except in okra). PCR-RAPD analysis was carried out using a set of 20 random primers which had produced repeatable banding patterns from a original set of 60 primers. A set of 155 amplicon levels were available for analysis, of which 154 were polymorphic. An average of 7.75 bands per primer was recorded. Similarity coefficients based on the frequency of band sharing among host strains varied from 0.25 in cotton and sunflower to 0.72 in groundnut. Clustering analysis on the basis of the PCR-RAPD-generating band sharing indicated that most of the individuals occurring on niger, safflower, green gram, abutilon and lagasca clustered together, indicating greater genetic similarity among themselves, than those occurring on other crops. Furthermore, the pattern of genetic variation in the individuals collected from niger, safflower, green gram, groundnut, abutilon and lagasca was seem to be largely host-dependent.
Pagire, Suvarna H.,Lee, Eunhye,Pagire, Haushabhau S.,Bae, Eun Jung,Ryu, Soo Jung,Lee, Dahye,Kim, Min Hee,Kim, Geum Ran,Hwang, Kyu-Seok,Ahn, Sukyung,Maeng, Jin Hee,Song, Jin Sook,Bae, Myung Ae,Lee, Don Pergamon Press 2018 Bioorganic & medicinal chemistry letters Vol.28 No.3
<P><B>Abstract</B></P> <P>A series of glutamic acid derivatives was synthesized and evaluated for their antioxidant activity and stability. We found several potent and stable glutamic acid derivatives. Among them, compound <B>12b</B> exhibited good <I>in vitro</I> activity, chemical stability and cytotoxicity. A prototype compound <B>12b</B> showed an anti-inflammatory effect in LPS-stimulated RAW 264.7 cell lines and in a zebrafish model.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Patil Suvarna,Bashasab Fakrudin,Vijaykumar Vijaykumar,Basavanagoud Basavanagoud,Kuruvinashetti Mahaling S,Patil Basavaraj V Korean Society of Applied Entomology 2006 Journal of Asia-Pacific Entomology Vol.9 No.3
The genetic relatedness among Helicoverpa armigera ($H\"{u}bner$) occurring on different host plants prevailing in South India was studied using PCR-RAPD. Genomic DNA was isolated individually from five larvae collected from each of 10 different host plants (except in okra). PCR-RAPD analysis was carried out using a set of 20 random primers which had produced repeatable banding patterns from a original set of 60 primers. A set of 155 amplicon levels were available for analysis, of which 154 were polymorphic. An average of 7.75 bands per primer was recorded. Similarity coefficients based on the frequency of band sharing among host strains varied from 0.25 in cotton and sunflower to 0.72 in groundnut. Clustering analysis on the basis of the PCR-RAPD-generating band sharing indicated that most of the individuals occurring on niger, safflower, green gram, abutilon and lagasca clustered together, indicating greater genetic similarity among themselves, than those occurring on other crops. Furthermore, the pattern of genetic variation in the individuals collected from niger, safflower, green gram, groundnut, abutilon and lagasca was seem to be largely host-dependent.
VL RECIPROCAL STATUS INDEX AND COINDEX OF CONNECTED GRAPHS
V. Lokesha,S. Suvarna,Shanthakumari Y 장전수학회 2022 Proceedings of the Jangjeon mathematical society Vol.25 No.3
The reciprocal status of a vertex u in a connected graph G, is defined as the sum of reciprocal of the distances between u and all other vertices of a graph G. Relation between VL reciprocal status index and VL reciprocal status coindices are established. Also these indices are computed for VL reciprocal status transmission regular graphs. Further the VL reciprocal status index and coindex of some standard graphs are obtained.
Biosynthesis of Xylobiose: A Strategic Way to Enrich the Value of Oil Palm Empty Fruit Bunch Fiber
( Lakshmi G ),( Suvarna B ),( Uma Rejeswari ),( R S Prakasham ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.8
Xylooligosaccharides are functional foods mainly produced during the hydrolysis of xylan by physical, chemical, or enzymatic methods. In this study, production of xylobiose was investigated using oil palm empty fruit bunch fiber (OPEFB) as a source material, by chemical and enzymatic methods. Xylanase-specific xylan hydrolysis followed by xylobiose production was observed. Among different xylanases, xylanase from FXY-1 released maximum xylobiose from pretreated OPEFB fiber, and this fungal strain was identified as Aspergillus terreus and subsequently deposited under the accession Number MTCC- 8661. The imperative role of lignin on xylooligosaccharides enzymatic synthesis was exemplified with the notice of xylobiose production only with delignified material. A maximum 262 mg of xylobiose was produced from 1.0 g of pretreated OPEFB fiber using FXY-1 xylanase (6,200 U/ml) at pH 6.0 and 45oC. At optimized environment, the yield of xylobiose was improved to 78.67 g/100 g (based on xylan in the pretreated OPEFB fiber).
VL Status Index and Co-index of Connected Graphs
V. Lokesha,S. Suvarna,A. Sinan Cevik 장전수학회 2021 Proceedings of the Jangjeon mathematical society Vol.24 No.3
The status σG(u) of a vertex u in a connected graph G is defined as the sum of the distances between u and all other vertices of G. In this paper some relations over VL status index and VL status co-index of connected graphs are established. Furthermore distinguished examples for k-transmission regular graphs and nanostructures of VL status indices are computed.
Synthesis and Diacylglycerol Acyltransferase-1 Inhibition of Azabicyclo[3.1.0]hexane Derivatives
한서정,이귀빈,곽현정,Suvarna H. Pagire,김지영,Haushabhau S. Pagire,박성범,채정학,이주윤,김기영,이상달,김희연,신선혜,배명애,박미진,김두섭,이덕형,안진희 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.6
We identified azabicyclo[3.1.0]hexane derivatives that are active diacylglycerol acyltransferase-1 (DGAT)-1 inhibitor. Among the azabicyclo[3.1.0]hexane series, compound 6b showed good in vitro activity toward human DGAT-1, selectivity toward DGAT-2, and liver microsomal stability. Compound 6b exhibited no CYP inhibition, hERG binding, or cell cytotoxicity. Additionally, compound 6b reduced the level of plasma triglyceride after oral administration in mice.
Topological coindices of phytochemicals examined for Covid-19 therapy
V. Lokesha,A. S. Maragadam,SUVARNA,ISMAIL NACI CANGUL 장전수학회 2023 Proceedings of the Jangjeon mathematical society Vol.26 No.4
Topological coindices of phytochemicals examined for Covid-19 therapy
Jang, Yoon Kyung,Lee, Kyu Myung,Jung, Kwan-Young,Kang, Seung Kyu,Pagire, Suvarna H.,Lee, Jun Mi,Pagire, Haushabhau S.,Kim, Kwang Rok,Bae, Myung Ae,Lee, Hohjai,Rhee, Sang Dal,Ahn, Jin Hee Pergamon Press 2017 Bioorganic & medicinal chemistry letters Vol.27 No.16
<P><B>Abstract</B></P> <P>A series of <I>N</I>-methoxyamide derivatives was identified and evaluated as GPR119 agonists. Several <I>N</I>-methoxyamides with thienopyrimidine and pyridine scaffolds showed potent GPR119 agonistic activities. Among them, compound <B>9c</B> displayed good in vitro activity and potency. Moreover, compound <B>9c</B> lowered glucose excursion in mice in an oral glucose tolerance test and increased GLP-1 secretion in intestinal cells.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>