Structural and magnetic properties of epitaxial Co₂FeAl films grown on MgO substrates for different growth temperatures

Chun, B.S.,Kim, K.H.,Leibing, N.,Serrano-Guisan, S.,Schumacher, H.W.,Abid, M.,Chu, I.C.,Mryasov, O.N.,Kim, D.K.,Wu, H.C.,Hwang, C.,Kim, Y.K. Elsevier Science 2012 ACTA MATERIALIA Vol.60 No.19

We report the correlation between the crystalline structure, electronic structure and magnetic properties of Co<SUB>2</SUB>FeAl films as a function of growing temperature both experimentally and theoretically. The Co<SUB>2</SUB>FeAl film grown at room temperature is initially in the partially disordered B2 state, but then it gains a much higher ordered structure with increasing growing temperature due to its transition from short-range to long-range crystallographic order by surface diffusion. Electron energy loss spectroscopy measurements reveals that the increase in the I(L3)/I(L2) ratio of Co can be attributed to the enhanced ferromagnetic exchange interaction between neighboring Co atoms and the fact that the Co contribution is more dominant than the Fe contribution. As the growing temperature increases, many more unoccupied 3d states in Co are observed, hence the Gilbert damping constant increases due to a strong spin-orbit interaction. We also present the results of highly accurate quasiparticle self-consistent GW calculations and confirm that Co<SUB>2</SUB>FeAl in an ideal L2<SUB>1</SUB> structure is indeed a half-metal with a well-defined band gap in the minority spin channel.

乳癌 手術後 放射線 治療療法의 에너지別 比較 評價

崔慶姬,秋成實,南正祐,崔炳肅 최신의학사 1977 最新醫學 Vol.20 No.2

Routine postoperative radiation therapy has been widely employed to supplement the surgical -procedure. Following radical mastectomy, the volume to be irradiated will be the full thickness of the chest wall over an irregular area and the draining lymphatic chains including axillary, supraclavicular and internal mammary nodes. The principal aim of radiotherapy is to deliver adequate dose of radiation to the tumor bearing tissue and at the same time to avoid excessive damage to the underlying normal tissue. The anatomy of the breast. chest wall and lymph node drainage areas make the satisfactory homogeneous high dose irradiation of the required volume extremely difficult to achieve and has led to the progressive development for better irradiation techniques. In this article, authors have extensively reviewed and collected the various radiotherapy techniques which has been used since the days of conventional x-ray therapy from around 1930s up to the present time. They were divided into the seven representative methods according to the different energies of radiation. Their characteristics, and advantage and disadvantage were evaluated and compared in the physical and technical aspects. Clinical results including survivals, local recurrence, and complications were compared following a review of related articles. Conventional orthovoltage radiation and cesium-137 therapy have been largely replaced with cobalt-60 and electron bean treatment. The most widely used methods at present time are tangential therapy using cobalt-60 and direct appositional treatment with the appropriate energies of electron beam. The high energy electron beam therapy which has been rapidly developed since 1960s produce slightly more skin reaction than cobalt-60, but it is mild in degree and have many practical merits. They include technical simplicity, easy dose plan and calculation, small probability of error. and less radiation pneumonitis than cobalt-60. No sufficient clinical results are yet available for comparison of treatment effects between the two methods, however electron beam seems to be more suitable for the treatment of postmastectomy chest wall in breast cancer.

Block of hERG K⁺ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration

Hong, H.K.,Hoon Lee, B.,Park, M.H.,Ho Lee, S.,Chu, D.,Jin Kim, W.,Choe, H.,Hee Choi, B.,Jo, S.H. North-Holland ; Elsevier Science Ltd 2013 european journal of pharmacology Vol.702 No.1

Fluphenazine is a potent antipsychotic drug that can increase action potential duration and induce QT prolongation in several animal models and in humans. As the block of cardiac human ether-a-go-go-related gene (hERG) channels is one of the leading causes of acquired long QT syndrome, we investigated the acute effects of fluphenazine on hERG channels to determine the electrophysiological basis for its proarrhythmic potential. Fluphenazine at concentrations of 0.1-1.0μM increased the action potential duration at 90% of repolarization (APD<SUB>90</SUB>) and action potential duration at 50% of repolarization (APD<SUB>50</SUB>) in 5min when action potentials were elicited under current-clamp conditions in guinea pig ventricular myocytes. We examined the effects of fluphenazine on hERG channels expressed in Xenopus oocytes and HEK293 cells using two-microelectrode voltage-clamp and patch-clamp techniques. The IC<SUB>50</SUB> for the fluphenazine-induced block of hERG currents in HEK293 cells at 36<SUP>o</SUP>C was 0.102μM at +20mV. Fluphenazine-induced a concentration-dependent decrease of the current amplitude at the end of the voltage steps and hERG tail currents. The fluphenazine-dependent hERG block in Xenopus oocytes increased progressively relative to the degree of depolarization. Fluphenazine affected the channels in the activated and inactivated states but not in the closed states, and the S6 domain mutation from tyrosine to alanine at amino acid 652 (Y652A) attenuated the hERG current block. These results suggest that the antipsychotic drug fluphenazine is a potent blocker of hERG channels, providing a molecular mechanism for the drug-induced arrhythmogenic side effects.

Status of the KSTAR superconducting magnet system development

Kim, K.,Park, H.K.,Park, K.R.,Lim, B.S.,Lee, S.I.,Chu, Y.,Chung, W.H.,Oh, Y.K.,Baek, S.H.,Lee, S.J.,Yonekawa, H.,Kim, J.S.,Kim, C.S.,Choi, J.Y.,Chang, Y.B.,Park, S.H.,Kim, D.J.,Song, N.H.,Kim, K.P.,So International Atomic Energy Agency 2005 Nuclear fusion Vol.45 No.8

<P>The aim of the Korea superconducting tokamak advanced research (KSTAR) project is to develop a steady-state-capable advanced superconducting tokamak for establishing a scientific and technological basis for an attractive fusion reactor. Since the KSTAR mission includes the achievement of a steady-state-capable operation, the use of superconducting coils is an obvious choice for the magnet system. The KSTAR superconducting magnet system consists of 16 toroidal field (TF) and 14 poloidal field (PF) coils which include 8 central solenoid coils. Both the TF and PF coil systems use internally-cooled cable-in-conduit conductors (CICC). The TF coil system provides a magnetic field of 3.5 T at the plasma centre and the PF coil system provide a flux swing of 17 V s. The major achievement in the KSTAR magnet system development includes the development of CICC, a full size TF model coil, a background magnetic field generation coil system and the construction of a large scale superconducting magnet and the CICC test facility. TF and PF coils are at the stage of fabrication for the KSTAR completion in the year 2007.</P>

高 에너지 電子線 治療時 體內 空洞으로 因한 線量分布 變動

秋成實,李道行,崔炳뭐 대한방사선방어학회 1976 방사선방어학회지 Vol.1 No.1

The perturbation of dose distribution adjacent to cavities in high energy electron has shown that the percentage of dose increase varies markedly as a function of the build-up layer, the length and thickness of the cavities, and the electron energy. The dose distribution showed that cavities similar in size to those encountered in the head and neck measured by industrial film dosimetry and corrected by ionization chambers. The most increased doses by measuring are resulted in a localized dose of up to 130% of that measured at the depth of maximum dose within a homogeneous tissue equivalent phantom. The measured values and correction factors of dose perturbation due to air cavities showed in diagrams and would be summarized as follows. 1. In 8∼12MeV electron beams, the most marked dose is observed when the build-up layer thickness is 0.5cm and cavity volume is 2×2×2cm³. 2. The highest dose point is located under cavity when the energy is increased and cavity length is longer. 3. The cavity length at which the maximum percentage dose occurs decreases with increasing energy. 4. The highest percentage cavity doses are obtained when the energy is high, the build-up layer is thin, the thickness of the cavity is large, and the length of the cavity is approximately 1 to 3cm. 5. The doses of upper portion of cavity are less than the standard dose distribution as 5 to 10%. 6. The maximum range of electron beam are extended as much as thickness of cavity. 7. A cavity having a length of 5cm closely approximates a cavity of infinite length.

마늘대 사일리지 급여가 한우거세우의 성장 및 도체특성에 미치는 영향

추교문,이호재,박정식,조희웅,안병홍 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.6

This study was conducted to investigate the effect of feeding or garlic stalk silage on performance and carcass characteristics of Hanwoo steers. Feeding trial was conducted with 27 heads of Hanwoo steers and these animals were divided into two groups control(rice straw) and garlic stalk silage. Animasl consuming rice straw were fed concentrates and rice straw for 22 months from the 5 months of age and animals consuming garlic stalk silage were fed concentrates, rice straw and garlic stalk silage for 22 months from the 5 months of age. Animals fed rice straw and garlic stalk silage were fed 1.34 and 1.47, 1.69 and 1.74, 1.65 and 1.66% concentrates to body weight for the growing period, fattening period and finishing period, respectively. Also, animals fed garlic stalk silage wee offered 0.22 and 0.33% garlic stalk silage to body weight for the fattening and finishing period, respectively. Animals fed rice straw and garlic stalk silage as a roughage sources did not differ in average daily gain during the whole feeding periods. Animals of control group consumed less concentrates and roughage than those fed garlic stalk silage during the whole feeding periods. However, feed efficiency was not significantly different between both treatments. Beef yield including backfat thickness, eye muscle area and carcass weight was slightly lower in the animals fed garlic stalk silage than in the animals fed rice straw even though there were no differences between both treatments. However, beef quality including beef color, fat color, texture, maturity and marbling score was slightly higher in the garlic stalk silage-fed animals than in the animals fed rice straw although there were not statistically different between both treatments. Animals consuming garlic stalk silage was significantly(p<0.05) lower in shear value than those fed rice straw. Amino acid composition including essential amino acid non-essential amino acid was not different between animals fed rice straw and garlic stalk silage. Eye muscle area of animals fed garlic stalk silage contained slightly higher oleic aced, less linoleic acid and arachidonic acid more linolenic acid than that of animals fed rice straw only as a roughage sources. So eye muscle area of animals fed garlic stalk silage contained more mono-unsaturated fatty acid than that of animals fed rice straw and ω6/ω3 ratio was narrower in the animals fed garlic stalk silage than in the animals fed rice straw. Economic income was higher by 20% in the animals fed garlic stalk silage than in the animals fed rice straw. Therefore, It may be concluded that feeding of garlic stalk silage as a roughage sources to steers during the fattening period seems to improve meat quality, fatty acid composition and economic income.

레이저 빔 프린터 나노가공품의 표면정밀도 향상에 관한 연구

추현식,성백섭 조선대학교 생산기술연구소 2006 生産技術硏究 Vol.28 No.2

Recent advances in high-tech industry and ultra precision machining technology have led to the development of a wide variety of new materials. The demand for LBP Polygon Mirror finishing parts has increased, which are mainly used for the motor of the printer. so ultra precision machining technology is required. It is important for Polygon Mirror to have the enough strength for the highUspeed rotation and high quality Polygon line surface. Polygon Mirror, high-tech nano finishing part, is used for optical instrument such as laser phnters, digital copiers, laser fax machines and bar-code readers, etc. Therefore, we have evaluated the machining precision of matehal surface and tried to determine the optimum machining conditions in order to improve machining precision of S3M. Also we have applied to the production line to reduce the defective proportion. As a result, we have obtained high quality precision of side surface machining in case that the number of revolutions, speed and movement were constant and cutting rate was 0.05 mm. Also we have obtained the same results from the 30 test specimens with constant rough-cutting during the Polygon line machining. The defective proportion decreased from 12 percent to 4-6 percent when the machining conditions selected during the test were applied to the real production line. It is expected that the defective proportion of products can be reduced if we conduct further research on the cleaning and heat treatment process.

정소실질내 유전자 도입에 의한 형질전환동물의 생산 - 2 . 형질전환 한국재래산양의 생산

김성현,윤창현,이병오,오석두,장규태,주학진,박미령 경상대학교 축산진흥연구소 1999 畜産振興硏究所報 Vol.26 No.1

이비인후과 의뢰환자의 임상통계적 고찰

천표,장병일,추광철,김선곤 대한이비인후과학회 1977 대한이비인후과학회지 두경부외과학 Vol.20 No.4

이차원전기영동법을 이용한 white muscle과 red muscle간의 단백질 발현양상의 비교분석

김남국,조중호,추교선,박혜란,박범영,김언현,이창수 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.5

The technique known as proteomics is useful for characterizing the protein expression pattern of a particular tissue or cell type as well as quantitatively identifying differences in the levels of individual proteins. In present study, we carried out the comparative expression patterns of white and red muscles. We used the two-dimensional electrophoresis(2-DE) for analyzing the protein expression. Proteins isolated from porcine white and red muscles were separated by 12% poly-acrylamide gel and then were detected by coomassie blue and silver staining. More than 600 protein spots were detected on each 2-DE gel. By visual analysis of the stained gel, five proteins were identified to be differentially expressed in the white vs red muscle. By database searching based on the molecular weights and pI(isoelectric point) of the five proteins, three of them were found to be most close to triponin Ⅰ, T and myoglobin. However, further researche is needed for identification and functional analysis of the unidentified proteins. In conclusion, we found five proteins, which are differentially expressed in the white vs red muscle. The functional analysis of the differentially expressed proteins will provide valuable information on biochemical characteristics of the muscle type.