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도시공원 이용자들의 형태 분석 및 이용 만족도에 관한 연구
박장근(Jang Geun Park),임란희(Ran Hee Lim),지용범(Yong Beom Ji),신희진(Hee Jin Shin) 한국여가레크리에이션학회 2001 한국여가레크리에이션학회지 Vol.21 No.-
The purpose of this study was to investigate of form analysis and extent of Satisfaction of people using park. For this study, the population was the user Mansuck Park in Suwon City from 06.06.2001 to 06.07.2001. Sampling was made according to the self-administration method The participants in the questionnaire were 224. From the analysis of data, this study reached the following coclusions. 1. An analysis of form ; 1) A walking was 53.1 percent according to the analysis of using form in traffic means. There were some differences by age, job, education level, income. 2) The evening was 41.5 percent , and the afternoon was 28.6 percent according to the time period of using. There were some differences in all items as gender, age, job, education level, income. 3) The family or relative was 48.2 percent, and the friends (lover) was 32.6 percent according to the companion. There were some differences in all items as gender, age, job, education level, income. 4) The rest and walk 50.0 percent , and meeting, talk was 17.4 percent according to the using park. There were some differences by gender, age, job, income. 5) The shade of a tree, bench, grass was 55.4 percent, and the promenade was 23.7 percent according to the place and facilities for using. There were some differences by age. 2 And extent of satisfaction for using park ; The satisfaction in the location of facilities, the management and scene of the park was in high content degree. But, the satisfaction in the number of facilities and the staff was in low content degree.
Tae-Yang Noh,Beom-Hee Lee,Byeong-Mok Park1,Ah-Ran Cha,Hee-Chul Yang 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Nuclear power plants in Korea stores approximately 3,800 drums of paraffin solidification products. Due to the lack of homogeneity, these solidification products are not allowed to be disposed of. There is therefore a need for the separation of paraffin from the solidification products. This work developed an equipment for a selective separation of paraffin from the solidification product using the vacuum evaporation and condensational recovery method in a closed system. The equipment mainly consists of a vacuum evaporator and a condensational deposition recovery chamber. Nonisothermal vacuum TGAs, kinetic analyses and kinetic predictions were conducted to set appropriate operation conditions. Its basic operability under the established conditions was first confirmed using pure paraffin solid. Simulated paraffin solidification product fixing dried boric acid waste including nonradioactive Co and Cs were then fabricated and tested for the capability of selective separation of paraffin from the simulated waste. Paraffin was selectively separated without entertainment of Co and Cs. It was confirmed that the developed equipment could separate and recover paraffin in the form of nonradioactive waste.
A literature review of <i>de qi</i> in clinical studies
Park, Ji-Eun,Ryu, Yeon-Hee,Liu, Yan,Jung, Hee-Jung,Kim, Ae-Ran,Jung, So-Young,Choi, Sun-Mi BMJ Publishing Group 2013 Acupuncture in medicine Vol.31 No.2
<P><B>Objectives</B></P><P><I>De qi</I> is a sensation experienced by a patient or an acupuncturist during acupuncture treatment. Although <I>de qi</I> is considered to be important in acupuncture treatment, there are not many studies about <I>de qi</I> and its character. The purpose of this study is to review <I>de qi</I> questionnaires and evaluate the relationship between <I>de qi</I> and acupuncture points, stimulation and treatment effects.</P><P><B>Methods</B></P><P>A search was conducted using three English-language databases (PubMed, Cochrane and ScienceDirect) and seven Korean databases with the keywords ‘<I>de qi</I>’ and ‘needle sensation’. The included studies were then categorised as following: (1) <I>de qi</I> measurement tools, (2) the relationship between <I>de qi</I> and acupuncture points, (3) the relationship between <I>de qi</I> and stimulation, (4) the relationship between <I>de qi</I> and treatment effects and (5) attitudes and opinions toward <I>de qi</I>.</P><P><B>Results</B></P><P>Several questionnaires have been developed to evaluate <I>de qi</I>, and the most frequent sensation in those questionnaires was ‘heavy’ and ‘numb’. Although a few studies showed specificity to acupuncture points, information is still lacking to be able to draw a clear conclusion about the relationship between <I>de qi</I> and acupuncture points. Also, greater <I>de qi</I> was elicited in real acupuncture than placebo acupuncture in many studies. The relationship between <I>de qi</I> and treatment effects was controversial.</P><P><B>Conclusions</B></P><P>It seems that real acupuncture induced greater <I>de qi</I> than sham acupuncture, and the relationship between <I>de qi</I>, acupuncture points and treatment effects was controversial. However, the current literature evaluating <I>de qi</I> is not sufficient to derive clear conclusions. Further studies with more objective indices and rigorous methodologies are needed.</P>
FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair
Park, Yun-Yong,Jung, Sung Yun,Jennings, Nicholas B,Rodriguez-Aguayo, Cristian,Peng, Guang,Lee, Se-Ran,Kim, Sang Bae,Kim, Kyounghyun,Leem, Sun-Hee,Lin, Shiaw-Yih,Lopez-Berestein, Gabriel,Sood, Anil K,L Oxford University Press 2012 Carcinogenesis Vol.33 No.10
<B>Abstract</B><P>Transcription factors are direct effectors of altered signaling pathways in cancer and frequently determine clinical outcomes in cancer patients. To uncover new transcription factors that would determine clinical outcomes in breast cancer, we systematically analyzed gene expression data from breast cancer patients. Our results revealed that Forkhead box protein M1 (FOXM1) is the top-ranked survival-associated transcription factor in patients with triple-negative breast cancer. Surprisingly, silencing FOXM1 expression led breast cancer cells to become more sensitive to doxorubicin (Dox). We found that FOXM1-dependent resistance to Dox is mediated by regulating DNA repair genes. We further demonstrated that NFκB1 interacts with FOXM1 in the presence of Dox to protect breast cancer cells from DNA damage. Finally, silencing FOXM1 expression in breast cancer cells in a mouse xenograft model significantly sensitized the cells to Dox. Our systematic approaches identified an unexpected role of FOXM1 in Dox resistance by regulating DNA repair genes, and our findings provide mechanistic insights into how FOXM1 mediates resistance to Dox and evidence that FOXM1 may be a promising therapeutic target for sensitizing breast cancer cells to Dox.</P>
( Hee Seung Hong ),( Jiwon Baek ),( Jae Chul Park ),( Ho-su Lee ),( Dohoon Park ),( A-ran Yoon ),( Soo Jung Park ),( Sung Noh Hong ),( Seong-joon Koh ),( Chang Kyun Lee ),( Bo-in Lee ),( Sung Wook Hwa 대한소화기기능성질환·운동학회 2022 Gut and Liver Vol.16 No.6
Background/Aims: Chronic enteropathy associated with SLCO2A1 gene (CEAS), an inherited disease characterized by nonspecific intestinal ulcers, has emerged in the Japanese population via loss-of-function mutations in the SLCO2A1 gene. We aimed to investigate the clinical and genetic characteristics of Korean patients diagnosed with CEAS. Methods: From July 2018 to July 2021, we performed Sanger sequencing of the SLCO2A1 gene in 46 patients with chronic intestinal ulcers. CEAS was confirmed based on known SLCO2A1 mutations. We summarized the clinical characteristics of patients with confirmed CEAS. Results: Fourteen out of 46 patients (30.4%) had genetically confirmed CEAS, and two SLCO2A1 variants were detected (splicing site variant c.940+1G>A and nonsense mutation [p.R603X] in SLCO2A1). Twelve patients (85.7%) were females and the median age at diagnosis of CEAS was 44.5 years. All patients presented with abdominal pain, and 13 patients (92.9%) presented with anemia (median hemoglobin, 9.6 g/dL). Ten patients (71.4%) had hypoalbuminemia (median, 2.7 g/dL). The most commonly involved site was the ileum (13/14, 92.9%). Manifestations of primary hypertrophic osteoarthropathy (PHO), such as digital clubbing, pachydermia, and periostosis were observed in five patients (28.6%) and two male patients and one female patient satisfied all major PHO diagnostic criteria. Conclusions: The clinical and genetic characteristics of Korean patients with confirmed CEAS were similar to those reported in the literature. CEAS should be considered in the differential diagnosis for patients with unexplained chronic nonspecific ulcers of the small intestine. (Gut Liver 2022;16:942-951)
A New Grafted Cactus with Bright Yellow Color, 'Hwangseon'
Park, Pil-Man,Jeong, Myeung-Il,Yae, Byeong-Woo,Kim, Mi-Sun,Lee, Young-Ran,Park, Pue-Hee,Yoo, Bong-Sik Korean Society of Horticultural Science 2012 원예과학기술지 Vol.30 No.3
A new grafted cactus cultivar, called 'Hwangseon', Gymnocalycium mihanovichii, is a hybrid crossed between two orange color cultivars 'Geoseong' and 'Huhwang'. Mating was performed in the greenhouse of National Institute of Horticultural & Herbal Science (NIHHS) in 2005. The harvested seeds were sown at 100 mL volumetric flasks filled with 'Kyoto' medium. Seedling had been grafted into a young rootstock, Hylocereus trigonus, and cultured in vitro in 100 mL test tube for more than six months. After re-grafting and planting in the green house in 2006, their characteristics were evaluated three times until 2009. The new cultivar has a flat round shape and bright yellow skin color. In addition, it has 7 to 9 ribs with gray and straight spines on the body and produces an average of 12.3 offsets.
Liquid crystal dimers having vary oxyethylene flexible spacers
Park, Joo Hoon,Singu, Bal Sydulu,Choi, Ok Byung,Lee, Hwan Myung,Lee, Jin Young,Kim, Sung Jo,Cha, Eun Hee,Park, Seon Nam,Kwak, Myeong Heon,So, Bong Keun,Kim, Ran Hee,Lee, Soo Min,Yoon, Kuk Ro Informa UK (TaylorFrancis) 2017 Molecular Crystals and Liquid Crystals Vol.650 No.1
<P>In this article, we are prepared that the liquid crystal dimers have aromatic-ester type mesogenic units or aromatic-Schiff base typemesogonic units and confirmed by H-1-NMR spectrometry. The mesomorphic and optical properties of the resultant dimers were studied by differential scanning calorimetry and polarizing optical microscopy.</P>