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      • KCI등재

        Behavior of Al/Cu/Ti electrodes in surface acoustic wave filter at high power

        Qi Li,Sulei Fu,Zengtian Lu,Lirong Qian,Rui Wang,Tongjin Chen,Cheng Song,Fei Zeng,Weibiao Wang,Feng Pan 한국물리학회 2019 Current Applied Physics Vol.19 No.4

        Driven by the need for high data-rates and continuous reduction in device size, surface acoustic wave filters are required to work under increasingly high power. In this work, a series of 2.7 GHz surface acoustic wave filters with Al/Cu/Ti three-layered electrode were fabricated and loaded with high power. Those three-layered electrodes showed weaker texture but higher stability than Al-Cu alloy electrode at high power. Morphologies, microstructures and elements distribution in cross section of fingers were analyzed carefully before and after high power loading. Results show that the circular-arc-shaped outline of fingers were appeared in most samples after high power loading, and the number of gains in the finger cross section changed from some into several with much larger volume. The features of distribution of Cu atoms also coincided with these microstructures. By finite element method and phase diagram analysis, the higher stability of Al/Cu/Ti three-layered electrodes are attributed to precipitation of θ-CuAl2 in the bottom edge of electrode finger and Cu-doped α-Al in the center top.

      • Microstructure and cutting performance of CrTiAlN coating for high-speed dry milling

        LU, Li,WANG, Qi-min,CHEN, Bing-zhou,AO, Yong-cui,YU, Dong-hai,WANG, Cheng-yong,WU, Shang-hua,KIM, Kwang Ho Elsevier 2014 Transactions of Nonferrous Metals Society of China Vol.24 No.6

        <P>Using a closed field unbalanced magnetron sputtering system, the cemented carbide end mills were coated with a CrTiAIN hard coating, which consisted of a Cr adhesive layer, a CrN interlayer and a CrTiAIN top layer. The microstructure and mechanical properties of the coating were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), micro indentation and scratch test. The cutting performance of the coated end mills were conducted by high-speed dry milling hardened steel (P20, HRC 45). The results indicates that the coating is composed of (Cr, Ti, Al)N columnar grains with nanolayers. The coating exhibits good adhesion to cemented carbide substrate and high microhardness of around 30 GPa. The coated end mills show significant improvement on tool life and much lower cutting force as compared to the uncoated ones. And the related mechanisms were discussed.</P>

      • KCI등재

        Stability and electronic properties of CuAlO2 (112 0) surfaces

        Cheng-Lu Jiang,Qi-Jun Liu,Fu-Sheng Liu,Zheng-Tang Liu 한국물리학회 2017 Current Applied Physics Vol.17 No.2

        We have studied the stability and electronic properties of CuAlO2 ð112 『 0Þ surfaces using the firstprinciples calculations. The structural parameters, band structures, surface energies, work functions, densities of states and charge densities of CuAlO2 ð112 『 0Þ surfaces have been investigated. The calculated results show that five layers are needed to maintain convergence. After the formation of surfaces, the bandgaps of stable surfaces decrease, the covalency between Cu and O atoms in surfaces increases, and the positive charge layer in the fisrt layer appears.

      • Relationships among MTHFR a1298c Gene Polymorphisms and Methylation Status of Dact1 Gene in Transitional Cell Carcinomas

        Cheng, Huan,Lu, Meng,Mao, Li-Jun,Wang, Jun-Qi,Li, Wang,Wen, Ru-Min,Chen, Jia-Cun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

        Objectives: The purpose of this study was to determine the relationship between methylation status of the Dact1 gene and MTHFR a1298c polymorphic forms in transitional cell carcinoma tissues in a Chinese population. Methods: Polymorphisms of folate metabolism enzyme gene MTHFR were assessed by restrictive fragment length polymorphism (RFLP) methods and PCR-based DNA methylation analysis was used to determine the CpG island methylation status of the Dact1 gene. Associations between the methylation status of the Dact1 gene and clinical characteristics, as well as MTHFR a1298c polymorphisms, were analyzed. Results: aberrant methylation of the Dact1 gene was found in 68.3% of cancer tissues and 12.4% of normal tissues,. The methylation rate of the Dact1 gene in cancer tissues was significantly higher in patients with lymph node metastasis than in those without lymph node metastasis (46.3% vs. 17.2%, P = 0.018). No association was found between aberrant DNA methylation and selected factors including sex, age, tobacco smoking, alcohol consumption and green tea consumption. After adjusting for potential confounding variables, variant allele of MTHFR a1298c was found to be associated with methylation of the Dact1 gene. Compared with wild type CC, the odds ratio was 4.33 (95% CI: 1.06-10.59) for AC and 4.95 (95% CI: 1.18-12.74) for AA. The N stage in TNM staging and the occurrence of lymph node metastasis were associated with an MTHFR 1298 AA+AC genotype (P<0.05). Conclusion: MTHFR 1298 AC and AA genotypes might help maintain a normal methylation status of the Dact1 gene, aberrant CpG island methylation of which is closely related to the genesis and progression of transitional cell carcinoma.

      • SCIESCOPUSKCI등재

        In vitro stability evaluation of coated lipase

        Liu, Lu Jie,Zhu, Jia,Wang, Bin,Cheng, Chu,Du, Yong Jie,Wang, Min Qi Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.2

        Objective: The study was conducted to evaluate the stability of commercial coated lipase (CT-LIP) in vitro. Methods: The capsules were tested under different conditions with a range of temperature, pH, dry heat treatment and steaming treatment, simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) in this work, respectively. Free lipase (uncoated lipase, UC-LIP) was the control group. Lipase relative activities measured in various treatments were used as a reference frame to characterize the stability. Results: The lipase activities were decreased with increasing temperatures (p<0.05), and there was a markedly decline (p<0.01) in lipase comparative activities of UC-LIP at $80^{\circ}C$ compared with CT-LIP group. Higher relative activities of lipase were observed in CT-LIP group compared with the free one under acidic ambient (pH 3 to 7) and an alkaline medium (pH 8 to 12). Residual lipase activities of CT-LIP group were increased (p<0.05) by 5.67% and 35.60% in dry heat and hydrothermal treatments, respectively. The lipase relative activity profile of CT-LIP was raised at first and dropped subsequently (p<0.05) compared with constantly reduced tendency of UC-LIP exposed to both SGF and SIF. Conclusion: The results suggest that the CT-LIP possesses relatively higher stability in comparison with the UC-LIP in vitro. The CT-LIP could retain the potential property to provide sustained release of lipase and thus improved its bioavailability in the gastrointestinal tract.

      • KCI등재

        Determination of Fluoride Concentration in Antarctic Krill (Euphausia superba) using Dielectric Spectroscopy

        Jianfeng Lu,Lina Qi,Wen Guo,Yishan Song,정용안,Yu‐dong Cheng,Yinzhe Jin 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.6

        The concentration of fluoride in Antarctic krill (Euphausia superb) was investigated using a coaxial probe method based on dielectric properties in the 0.3–10 GHz frequency range. A quantitative relationship between the fluoride concentration in the aqueous solution and the dielectric loss at 0.3 GHz was also established with a regression coefficient over 0.98. The concentrations of fluoride in fresh and dried krill samples with different krill positions, such as shell and meat, were determined. The detected value agrees well with that determined using other methods, such as fluoride ion-selective electrode (ISE) and potassium permanganate titration (PPT). The fluoride concentrations in fresh krill were 0.0127, 0.0133, and 0.0152 mg/mL using dielectric spectroscopy, PPT, and ISE, respectively. These results show that the proposed dielectric loss technique is suitable and effective for determining fluoride content in Antarctic krill.

      • KCI등재

        Study of the relationship between variants near CCNL1/LEKR1 and in ADCY5 with low birth weight in a Chinese population

        Xuejin Fan,Qi Peng,Yanhua Chen,Zeke Ma,Xiaoguang He,Biying Deng,Hui Huang,Juan Zeng,Chuyun Cheng,Shaoji Liu,Xiaomei Lu 한국유전학회 2015 Genes & Genomics Vol.37 No.12

        The aim of this study was to test the impact of variants rs900400 (located near LEKR1 and CCNL1) and rs9883204 (located in ADCY5) on birth weight in a Chinese population. We conducted a case–control study including 156 low-birth- weight infants as the case group and 100 normal-birth-weight infants as the control group. The rs900400 and rs9883204 variants were analyzed by gene sequencing in all the participants. Our results revealed a significant difference in the genotype distribution (v2 = 10.449, p = 0.005) and allele distribution (v2 = 9.277, p = 0.002) of rs900400 between the case group and the control group. The C allele of rs900400 was associated with lower birth weight (OR 1.771 [95 % CI 1.237–2.535]) in the Chinese population. However, the rs9883204 polymorphism was not informative in the Chinese population. Our study shows that the ‘‘birth weightlowering’’ variant rs900400 located near LEKR1 and CCNL1, which is strongly associated with birth weight in European cohorts, appears to have a similar association in Chinese cohorts. However, the rs9883204 variant located in ADCY5 does not appear to be correlated with low birth weight in the same population. Moreover, we found that the variant rs900400 may also be associated with premature birth, thereby supporting the need for further research in this area.

      • KCI등재

        Impact of a Glyphosate-Tolerant Soybean Line on the Rhizobacteria, Revealed by Illumina MiSeq

        ( Gui-hua Lu ),( Yin-ling Zhu ),( Ling-ru Kong ),( Jing Cheng ),( Cheng-yi Tang ),( Xiao-mei Hua ),( Fan-fan Meng ),( Yan-jun Pang ),( Rong-wu Yang ),( Jin-liang Qi ),( Yong-hua Yang ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.3

        The global commercial cultivation of transgenic crops, including glyphosate-tolerant soybean, has increased widely in recent decades with potential impact on the environment. The bulk of previous studies showed different results on the effects of the release of transgenic plants on the soil microbial community, especially rhizosphere bacteria. In this study, comparative analyses of the bacterial communities in the rhizosphere soils and surrounding soils were performed between the glyphosate-tolerant soybean line NZL06-698 (or simply N698), containing a glyphosate-insensitive EPSPS gene, and its control cultivar Mengdou12 (or simply MD12), by a 16S ribosomal RNA gene (16S rDNA) amplicon sequencing-based Illumina MiSeq platform. No statistically significant difference was found in the overall alpha diversity of the rhizosphere bacterial communities, although the species richness and evenness of the bacteria increased in the rhizosphere of N698 compared with that of MD12. Some influence on phylogenetic diversity of the rhizosphere bacterial communities was found between N698 and MD12 by beta diversity analysis based on weighted UniFrac distance. Furthermore, the relative abundances of part rhizosphere bacterial phyla and genera, which included some nitrogen-fixing bacteria, were significantly different between N698 and MD12. Our present results indicate some impact of the glyphosate-tolerant soybean line N698 on the phylogenetic diversity of rhizosphere bacterial communities together with a significant difference in the relative abundances of part rhizosphere bacteria at different classification levels as compared with its control cultivar MD12, when a comparative analysis of surrounding soils between N698 and MD12 was used as a systematic contrast study.

      • Rapid assessment of suspension bridge deformation under concentrated live load considering main beam stiffness: An analytical method

        Wen-ming Zhang,Jia-qi Chang,Xing-hang Shen,Xiao-fan Lu,Tian-cheng Liu 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.88 No.1

        With the gradual implementation of long-span suspension bridges into high-speed railway operations, the main beam’s bending stiffness contribution to the live load response permanently grows. Since another critical control parameter of railway suspension bridges is the beam-end rotation angle, it should not be ignored by treating the main beam deflection as the only deformation response. To this end, the current study refines the existing method of the main cable shape and simply supported beam bending moment analogy. The bending stiffness of the main beam is considered, and the main beam’s analytical expressions of deflection and rotation angle in the whole span are obtained using the cable-beam deformation coordination relationship. Taking a railway suspension bridge as an example, the effectiveness and accuracy of the proposed analytical method are verified by the finite element method (FEM). Comparison of the results by FEM and the analytical method ignoring the main beam stiffness revealed that the bending stiffness of the main beam strongly contributed to the live load response. Under the same live load, as the main beam stiffness increases, the overall deformation of the structure decreases, and the reduction is particularly noticeable at locations with original larger deformations. When the main beam stiffness is increased to a certain extent, the stiffening effect is no longer pronounced.

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