衛氏朝鮮興亡考

李丙燾 서울대학교 1956 서울대학교 論文集 Vol.4 No.-

The Effect of Cyclosporin A on the Growth of human Glioma Cell Lines

Pyen, Jhin-Soo,Kim, Soo-Kie,Choi, Sun-Ju,Park, Yoon-Sun,Cho, Hyun-Chul,Han, Young-Pyo The Pharmaceutical Society of Korea 1997 Archives of Pharmacal Research Vol.20 No.4

Cyclosporin A, an potent immunosuppressant, has been known to be one of the modulators of drug resistance as well as a cytostatic drug. Despite many attempts to basic or clinical application of cyclosporin A, there are few reports on the inhibition of brain tumor cells. In the present experiment, the possibility of cyclosporin A as synergic adjuvant was investigated by MTT assay, $[^{3}H]$ thymidine uptake and through flowcytometric anaysis. Sole treatment of cyclosporin A on the CRT and CH235-MG glioma cell line revealed dose dependent cytotoxicity within a range of tested dose. Combined treatment of cyclosporin A with ACNU, BCNU and hydroxyurea on various glioma cancer cell line led to a significant synergistic cytotoxicity as well as inhibition of DNA synthesis with dose-dependency. In addition, cyclosporin A alone or combined treatment caused discernible changes of cell cycle in the tested cells. These data provide that cyclosporin A could potentiate the effect of nitrosourea compounds in vitro on human glioma cells.

감사태도와 감사표현이 연인관계 만족도에 미치는 영향 : 자기자비와 사회적 지지를 매개로

변상원(Pyen, Sangwon),이동귀(Lee, Donggwi) 한국재활심리학회 2020 재활심리연구 Vol.27 No.1

본 연구는 감사태도와 감사표현이 연인관계 만족도에 영향을 미치는 과정에서 자기자비와 지각된 사회적 지지가 매개하는 연구모형을 경험적으로 검증하였다. 서울 소재 대학생 334명을 대상으로 감사태도, 감사표현, 자기자비, 지각된 사회적 지지 및 연인관계 만족도를 측정하는 온라인 설문을 실시하였고, 이 중 현재 연인관계에 있다고 보고한 173명(남성 69명, 여성 104명)의 자료만 분석에 사용하였다. 주요 결과로 첫째, 감사태도, 감사표현, 자기자비, 지각된 사회적 지지, 연인관계 만족도 간에는 모두 유의한 정적 상관이 나타났다. 둘째, 연구가설대로 감사태도는 자기자비 수준을 높여 연인관계 만족을 증진하였고, 감사표현은 사회적으로 지지받고 있다는 인식을 고양하여 연인관계 만족도를 높이는 것으로 나타났다. 연구 결과를 바탕으로 본 연구의 시사점과 제한점 및 후속 연구에 대한 제안점을 논의하였다. This study empirically examined how gratitude attitude and gratitude expression affect romantic relationship satisfaction as well as the mediating effects of self-compassion and perceived social support in these processes. A sample of 334 undergraduate students from Seoul were recruited to complete an online survey on gratitude attitude, gratitude expression, self-compassion, perceived social support, and romantic relationship satisfaction. The final sample included 173 undergraduates (69 males, 104 females) who were in romantic relationships at the time of the survey. The results revealed significant positive correlations between gratitude attitude, gratitude expression, self-compassion, perceived social support, and romantic relationship satisfaction. Additionally, as hypothesized, gratitude attitude significantly enhanced romantic relationship satisfaction by increasing self-compassion, while gratitude expression significantly increased romantic relationship satisfaction by boosting one s perceived social support. The implications and limitations of this study and recommendations for future research are discussed.

작동 압력과 연료 공급 유량 변화가 고분자 전해질 연료전지 성능에 미치는 영향

편원형(Won-Hyeng Pyen),이상훈(Sang-Hoon Lee),이동호(Dong-Ho Rhee),조형희(Hyung Hee Cho) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.11

Operating pressure and mass flow rate of H₂/air are the dominant parameters affecting the performance of PEMFC. To investigate effects of operating pressure and mass flow rate of reactants on the performance of fuel cell, the performance measurements were executed for a unit cell of PEMFC. The active area is 100 ㎠ and each separator made of graphite has a serpentine flow path. The operating pressure ranges from atmospheric pressure to 2 kgf/㎠, while mass flow rate of reactants from 0.3 and 3.5 times ideal value. As a result of this study, the operating pressure of 1 kgf/㎠ has 27% higher performance of PEMFC than atmospheric pressure case. However, the performance for the operating pressure of 2kgf/㎠ is almost similar to that of 1 kgf/㎠. The performance is improved by increasing mass flow rate of air, while increasing mass flow rate of H₂ hardly affects the performance of fuel cell.

濟州道産 소라의 稚貝生産 및 棲息生態에 關한 硏究

변충규(Choong Kyu Pyen),윤정수(Jeong Su Youn) 한국수산과학회 양식분과 1990 韓國養殖學會誌 Vol.3 No.1

전복의 치패사육과 성장에 관한 연구

변충규,정상철 제주대학교 해양연구소 1984 해양자원연구소연구보고 Vol.8 No.-

Rearing and growth of young abalone (Haliotis discus) was studied from January 1983 to December 1983. The experiment was carried out in the Cheju fisheries seed culture center. The results obtained are as follows ; 1. The growth rate of abalones spawned in spring was superior to that of those spawned in fall . Those spawned in September and October were bigger than those spawned in November. 2. The growth of young abalone spawned by the same adult population were collected under similar condition was classified into the good and poor groups. Their growth equations were L_(t)=67.180(I-e^(-0.697(t-0.140))), L_(t)=52.635 (I-e^(0.669(t-0.235))), respectively. 3. The relationship between shell length and weight of young abalones is shown as follows : W=0.3800L^(2.1715) 4. The growth and survival rate according by materials in the outdoor aquarium were not difference. As the shell length was larger, the survival rate was higher. 5. Leaves of broader and softer tissue such as brown seaweed were efficient in increase of shell length and weight of the young abalones.

汽水湖(香湖.梅湖ㆍ永郞湖ㆍ松池湖ㆍ花津浦)의 環境 및 生物相 調査 報告

卞忠圭 제주대학교 1984 논문집 Vol.18 No.-

1. 5個湖沼內의 水溫範圍는 表層이 0.20∼27.3℃ 이며 底層이 0.4∼27.1℃로서 冬期에는 表面이 氷板狀態가 持續되었다. 2. 5個湖沼內의 鹽分濃度範圍는 表層이 0.78∼21.52%, 底層이 1.04∼22.35%로서 各湖沼마다 降雨量과 波浪時의 海水流入에 따라 鹽分濃度變化가 심한 편이었고, 大體로 春季가 높고 夏季가 낮은 편이었다. 3. 5個湖沼內의 溶存酸素量 範圍는 表層이 5.41∼8.93ml/l, 底層이 4.51∼8.86ml/l였고, 窒酸鹽(NO2-N) 範圍는 表層이 0.047∼0.484㎍-at/l, 底層이 0.016∼0.483㎍-at/l 였고, 燐酸鹽 (PO4-P)範圍는 表層이 0.013∼0.0381㎍-at/l, 底層이 0.022∼0.510㎍-at/l였다. 4. 5個湖沼內에서의 採集된 魚類는 14科 18種으로서 그中 붕어ㆍ황어ㆍ숭어ㆍ뱀장어ㆍ꾸구리ㆍ감성돔ㆍ전어 等은 各湖沼마다 採集되었고 大部分이 溫水性이며, 鹹ㆍ淡水에 適應力이 强한 魚種이였다. 5. 5個湖沼內의 植物性浮游生物의 出現種類數는 49屬 125種中 硅藻類가 33屬 102 種, 綠藻類 12屬 18種, 鹽藻類 4屬 5種으로서 硅藻類가 가장 많은 편이였다. 그外 原生動物類인 鞭毛蟲類가 5屬 7種, 纖毛蟲類가 4屬 4種, 輪蟲類가 1屬 1種, 그리고 甲殼類인 橈脚類(copepoda)와 各種浮游卵等이 出現되었다. 6. 植物性浮游生物의 分布相은 淡水産이 38種으로서 30.4%, 汽水産이 29種으로 23.2%였고, 沿岸外洋性海水産이 27種으로서 21.6%이며 海水ㆍ汽水ㆍ淡水域에 混在하고 있는 種類는 31種으로 全體의 24.8%였다. The monthly fluctuation of the environmental factors and the habitats of fishes in five lakes were surveyed (Hyang Ho, Mae Ho, Yeong Rang Ho, Song Ji Ho, and Hwa Jin Po) in Kangwon-do areas. Followings are the results obtained from this survey. 1) The ranges of temperature at five lakes were from 0.2℃ to 27.3℃ at surface and from 0.6℃ to 27.1℃ at bottom through the year. The surface water was frozen in winter. 2) The yearly changes of salinity were from 0.78 to 21.52% at the surface and from 1.04 to 22.35% at the bottom, which was principally influenced by changes of the amount of rainfall and inflow of sea water. Generally, salinity showed higher value in spring and lower in summer. 3) The dissolved oxygen ranged from 5.41 to 8.93ml/l at the surface and from 4.51 to 8.86ml/l at the bootom in each lakes. The amounts of nutrient salts (NO₂-N, PO₄-P) in each lakes were as followos: NO₂-N; surface 0.047 - 0.484 ug-atomas/1 bottom 0.016 - 0.438 ug-atoms/1 PO₄-P; surface 0.013 - 0.0381 ug-atoms/1 bottom 0.022 - 0.510 ug-atoms/1 4) The fish sampled from the five lakes were identified as 18 species of 14 families. Among them, Carp(C yprirnus carpio), Fall fish (Jribolodon hakonensis), Mullet(Mugil cephalus), Eel(Anguila japonica), Loach(Gobiobotia macrocephalus), Black sea bream(Mylio macrocephalus), and Hichoryshad(Konosirus punctatus), etc. were common in each lake. Most of them were warm water fish and also adaptable to both salty water and fresh water. 5) The flora of phytoplankton of 125 species belonging to 49 genera from the five lakes were collected. Among them, 33 genera, 102 species of Bacillario phyceae (Diatoms), 12 genera, 18 species of Chlorophyceae were identified. Especially, among Diatoms, genus Nitzschia was dominant. Protozoans were found, 7 species of Chromonadea belonging to 5 genera, 4 species of ciliates of 4 genera and 1 species of rotatoria. Some copepods and planktonic eggs were collected also. 6) The quantitative compositions of phytoplankton were as follows : Fresh water species were 30.4%(38 spp.), salty water species 23.2%(29 spp.) and coastal water species 21.6%(27 spp.). And the rest of the 24.8% was consisted of the euryhaline species(31 spp).

진주조개(Pinctada fucata)의 치패생산 및 양식에 관한 환경학적 연구-(2) : 천연채묘와 월동사육

변충규,노섬,전득산 제주대학교 해양연구소 1986 해양자원연구소연구보고 Vol.10 No.-

자기공명영상 추적관찰에 의한 뇌실출혈의 임상분석

변진수,황금,허철,김헌주,홍순기,한용표,이명섭 연세대학교 원주의과대학 1999 원주의대논문집 Vol.12 No.1

眞珠조개 (Pinctada fucata)의 稚貝生産 및 養殖에 關한 環境學的 硏究-(2) : 天然採苗와 越冬飼育 The Seed Collection in Natural Habitat and the Wintering

卞忠圭,盧暹,全得山 濟州大學校海洋資源硏究所 1986 해양과환경연구소 연구논문집 Vol.10 No.-

1. 慶南 閑山灣內에 있어서의 眞珠조개 (Pinctada fucata) 浮游幼生의 出現時期는 7月 中旬에서 8月 下旬까지 盛期를 나타내었고 D型幼生에서 Umbo 幼生으로 成長하는데 12月 內外가 經過되었다. 2. 1月부터 6月까지의 眞珠조개의 成長은 5月까지는 別差가 없었으며 6月부터는 成長差를 나타내었다. 3. 越冬期間의 斃死率 範圍는 西歸浦쪽 地先이 0.3-2.5%였고 巨文島 地先에서는 0.6-5.5%였다. 4. 濟州道 西歸浦 港口內의 4月의 平均水溫은 15.3℃ 였고 1月에서 3月까지의 平均水溫 範圍는 14.5-15.2℃로서 13℃를 上廻하고 있었다. In Hansan bay, drifting larvae of peal oyster (Pinctada fucata) appeared most abundantly from mid July to late August in 1985. The transition from D shape larvae to Umbo stage larvae required 12 days approximately. Mortality in winter were ranged 0.3-2.5% and 0.6-5.5% at Seogwipo culture bed and Komun Do culture bed respectively. At the harbor area of Seogwipo in Cheju Do, the average water temperature were ranged 14.5-15.2℃, recording 13℃ at the lowest from January to March. It rised to 15.3℃ in April.