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Nguyen,Thang Quyet,Ngo,Thanh Phuong Quynh 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-
Human resource is a key element for developing Tourism in Vietnam. As the most important destination of Vietnam Tourism, Ho Chi Minh city (also known as HCMC) welcomes 60 % total international tourists in Vietnam every year, but the qualification of training for HCMC tourism human resource is rated as low- quality as well as quantity, under the requirements of development and global integration. By synthesizing, document study combined with the survey method; this study has in-depth exploratory, analysis on the reality to conducted reasons of difficulties in human resource training in the Tourism industry, facing by universities, college, vocational centers majored in Tourism (also known as tourism institutions) in Ho Chi Minh City. The result has indicated the enterprises’ evaluation and difficulties in improving the qualification of tourism institutions. Therefore, the report proposed some solutions to improve training human resource efficiency in this field.
Nguyen Phuong Thao,Bui Thi Thuy Luyen,Chau Ngoc Diep,Bui Huu Tai,김은지,강희경,이상현,장해동,Nguyen The Cuong,Nguyen Van Thanh,Nguyen Xuan Cuong,Nguyen Hoai Nam,Chau Van Minh,김영호 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.4
This study performed phytochemical and bioactiveassessments of the mangrove Lumnitzera racemosaWilld. leaves. Bioassay-guided fractionation of the methanolicextracts led to the identification of thirty-six compounds(1–36), their structures were elucidated using detailed NMRspectroscopic and MS analysis. The extracts, fractions, andthe isolated compounds were screened for potential antioxidantand cytotoxic activities. Antioxidant assays wereperformed using peroxyl radical-scavenging and reducingassays, whereas cytotoxicity was measured using MTTassays in HL-60 and Hel-299 cell lines. The methanolicextract, CH2Cl2 and n-BuOH fractions (10.0 lg/mL)exhibited potent antioxidant activity, with Trolox equivalent(TE) values of 24.94 ± 0.59, 28.34 ± 0.20, and27.09 ± 0.37 (lM), respectively. In addition, the isolatedcompounds exerted cytotoxic effects in a dose-dependentmanner; compounds 1 and 14 exhibited the most potentcytotoxicity in HL-60 cells, with IC50 values of 0.15 ± 0.29and 0.60 ± 0.16 lM, respectively. To clarify the mechanism(s) behind these cytotoxic effects, we measured thetime-dependent changes in apoptotic markers including thecondensation and fragmentation of nuclear chromatin, andthe downregulation of p-ERK1/2, p-AKT, and c-Myc levels.
A New Sterol from the Soft Coral Lobophytum crassum
Nguyen, Phuong Thao,Nguyen, Hoai Nam,Nguyen, Xuan Cuong,Nguyen, Xuan Nhiem,Pham, The Tung,Tran, Hong Quang,Nguyen, Thi Thanh Ngan,Phan, Van Kiem,Chau, Van Minh,Kim, Young Ho Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.1
Nguyen Thu Hien,Nguyen Duc Quan,Kim Lien Nguyen Thi,Thi Thanh Ngan Nguyen,Nguyen Thi Phuong Mai,Tran Ngoc Dung,Nguyen Huy Hoang 한국유전학회 2023 Genes & Genomics Vol.45 No.4
Background Androgens and androgen receptor (AR) are critical regulators of the masculinization process in male sexual development. The absence of a functioning AR results in the development of the androgen insensitivity syndrome (AIS), a rare disorder of sexual development (DSD) characterized by the external genitalia feminization, gynecomastia, and impaired spermatogenesis. Objective To determine the AR gene mutations associated with male DSD in four unrelated Vietnamese patients. Methods To detect the disease-causing mutations, whole exome sequencing (WES) was performed on four patients diagnosed with AIS. Sanger sequencing was then used for validation of the identified mutations. Finally, 12 web-based tools, three-dimensional protein modeling software, and the guidelines issued by the American College of Medical Genetics and Genomics were used to assess the potential pathogenicity of these mutations. Results Four distinct novel mutations, namely c.1834T > A (p.Cys612Ser), c.2122 C > G (p.Leu708Val), c.2630T > G (p.Phe877Cys), and c.2641 C > A (p.Leu881Met) in the AR gene, were identified in four AIS patients using WES. The in silico analysis results revealed that the Cys612, Leu708, Phe877, and Leu881 sites are important for an appropriate response to androgens of the AR, and mutation at these sites can have adverse effects on the AR functions, androgen–AR interaction, and AR signaling pathway. Conclusions WES and in silico analyses strongly suggested that four novel AR mutations are pathogenic and have led to the development of AIS in the four Vietnamese patients under consideration.
Anti-inflammatory tirucallane saponins from Paramignya scandens.
Phan, Nguyen Huu Toan,Thuan, Nguyen Thi Dieu,Ngoc, Ninh Thi,Thao, Nguyen Phuong,Kim, Sohyun,Koh, Young Sang,Thanh, Nguyen Van,Cuong, Nguyen Xuan,Nam, Nguyen Hoai,Kiem, Phan Van,Kim, Young Ho,Minh, Cha Pharmaceutical Society of Japan 2015 Chemical & pharmaceutical bulletin Vol.63 No.7
<P>Five new tirucallane saponins, paramignyosides A-E (1-5), were isolated from the water fraction of the Paramignya scandens stem and leaves. Their structures were elucidated on the basis of spectroscopic evidence including high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and one dimensional (1D)- and 2D-NMR. The effects of isolated compounds on pro-inflammatory cytokines were evaluated by measuring the production of interleukin (IL)-12 p40, IL-6, and tumor necrosis factor-α (TNF-α) in lipopolysaccharide (LPS)-stimulated bone marrow-derived dendritic cells (BMDCs). Paramignyoside C (3) exhibited selective and potent inhibitory effect (IC50=5.030.19??M) on the production of IL-12 p40 comparable to that of the positive control, SB203580 (IC50=5.000.16??M). Further studies are required to confirm efficacy in vivo and the mechanism of anti-inflammatory effects.</P>
Anti-inflammatory Asterosaponins from the Starfish <i>Astropecten monacanthus</i>
Thao, Nguyen Phuong,Cuong, Nguyen Xuan,Luyen, Bui Thi Thuy,Thanh, Nguyen Van,Nhiem, Nguyen Xuan,Koh, Young-Sang,Ly, Bui Minh,Nam, Nguyen Hoai,Kiem, Phan Van,Minh, Chau Van,Kim, Young Ho American Chemical Society and American Society of 2013 Journal of natural products Vol.76 No.9
<P>Four new asterosaponins, astrosteriosides A–D (<B>1</B>–<B>3</B> and <B>5</B>), and two known compounds, psilasteroside (<B>4</B>) and marthasteroside B (<B>6</B>), were isolated from the MeOH extract of the edible Vietnamese starfish <I>Astropecten monacanthus</I>. Their structures were elucidated by chemical and spectroscopic methods including FTICRMS and 1D and 2D NMR experiments. The effects of the extracts and isolated compounds on pro-inflammatory cytokines were evaluated by measuring the production of IL-12 p40, IL-6, and TNF-α in LPS-stimulated bone marrow-derived dendritic cells. Compounds <B>1</B>, <B>5</B>, and <B>6</B> exhibited potent anti-inflammatory activity comparable to that of the positive control. Further studies are required to confirm efficacy <I>in vivo</I> and the mechanism of effects. Such potent anti-inflammatory activities render compounds <B>1</B>, <B>5</B>, and <B>6</B> important materials for further applications including complementary inflammation remedies and/or functional foods and nutraceuticals.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jnprdf/2013/jnprdf.2013.76.issue-9/np400492a/production/images/medium/np-2013-00492a_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/np400492a'>ACS Electronic Supporting Info</A></P>
Thi Phuong Diu TRAN(Thi Phuong Diu TRAN ),Thi Van Khanh NGUYEN(Thi Van Khanh NGUYEN ),Thanh Quang DO3(Thanh Quang DO3 ),Cong Nghiep NGUYEN(Cong Nghiep NGUYEN ),Thu Thuy LUONG(Thu Thuy LUONG ) 한국유통과학회 2022 유통과학연구 Vol.20 No.10
Purpose: This article focuses on exploring the associations between job satisfaction, organizational commitment, and turnover intention. Specifically, this study estimates the impacts of Vietnamese employees’ job satisfaction on their organizational commitment and turnover intention in FDI enterprises. Research design, data and methodology: The measures are adapted from previous studies to develop a questionnaire with a seven-point Likert scale. The dataset is directly collected from 227 respondents who are employees at FDI enterprises situated in the North of Vietnam. The dataset is analyzed by quantitative approaches using SPSS 24.0 and AMOS 24.0. Results: The results show that while turnover intention is positively correlated with monthly income, it is negatively correlated with job satisfaction and organizational commitment. Also, organizational commitment is positively associated with job satisfaction among employees at FDI enterprises in Vietnam. Conclusions: The findings of this study will serve as useful references for administrators of FDI enterprises and policymakers to promote employees’ job satisfaction and retain skilled employees.
An Empirial Study on Vietnam’s Trade Faclilitation in the Digital Economy
Thanh Huong Vu(Thanh Huong Vu ),Thi Thuy Hanh Lam(Thi Thuy Hanh Lam ),Ha Phuong Nguyen(Ha Phuong Nguyen ) The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.2
Purpose - Vietnam is among the fastest growing digital economies in the Southeast Asian region, and has made enormous efforts to adopt digital measures to facilitate trade. The paper aims to assess Vietnam’s performance of digital trade facilitation and estimate the impact of digital trade facilitation on Vietnam’s exports to the Association of Southeast Asian Nations (ASEAN). Design/Methodology/Approach - Vietnam’s implementation of digital trade facilitation is assessed through a constructed framework based on two groups of indicators, including Information Availability and Formalities Automation extracted from the OECD Trade Facilitation database. Further, a gravity model was adopted to estimate the impact of digital trade facilitation on Vietnam’s exports. Findings - The results show that Vietnam performs a slightly better than the average level of ASEAN countries. However, Vietnam’s implementation of digital trade facilitation tends to be ỉmproving at a slower rate than other ASEAN countries’ implementations, as well as the country’s overall implementation of other trade facilitation. The paper is among leading studies to quantify the impact of digital trade facilitation on Vietnam’s exports to ASEAN countries, and finds that if Vietnam and ASEAN countries increase trade facilitation through Information Availability measures by 1%, Vietnam’s exports will increase more than proportionately by 1.29% and 1.01%, respectively. Meanwhile, the digitalization of trade formalities so far has had no effect on Vietnam’s exports to this region. Research Implications - Vietnam should place priority on enhancing automation in trade-related administrative procedures, especially in customs procedures. Furthermore, it should pay more attention to promote the electronic publication of trade-related information, enhance the transparency of government policymaking, and increase the quality of enquiry points.
Phuong Ngoc Duy NGUYEN,Linh Le Khanh NGUYEN,Dong Nguyen Thanh LE 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.8
The purpose of this study is to explore the link between job satisfaction and organizational commitment at higher education institutions (HEIs) in emerging countries such as Vietnam and to determine extrinsic work factors that influence job satisfaction. Higher education is critical for socio-economic growth and the overall development of each country. Hence, an understanding of what motivates employees’ actions and attitudes should be obtained before determining the extent of employee satisfaction. The conceptual model was developed by incorporating job satisfaction-related variables, their relationships, and the impact of job satisfaction on organizational commitment. An empirical study was conducted on a study sample of public and private universities, with 316 academics and non-academic employees surveyed. The current study employed the partial least squares structural equation modeling to test the proposed hypotheses. The results reveal a positive and significant relationship between job satisfaction and organizational commitment. The findings confirm that extrinsic work factors (job itself, supervision, working conditions, payment, and reward and recognition) have a positive and significant relationship with job satisfaction. Furthermore, the study indicates that employees at HEIs who have a high level of ability utilization and supervisor support are more likely to be satisfied with their jobs.