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Phuc Thinh Doan,Pandu Sandi Pratama,Suk Yoel Kim,Hak Kyeong Kim,Hwang Yeong Yeun,Gi Sig Byun,Sang Bong Kim 한국해양공학회 2011 韓國海洋工學會誌 Vol.25 No.6
This paper describes a new method for a digital gas metal arc welding (GMAW) system. The GMAW system is an arc welding process that incorporates the GMAW power source (PS-GMAW) with a wire feed unit (WFU). The PS-GMAW requires an electric power of constant voltage. A constant magnitude is maintained for the arc current by controlling the wire-feed speed of the WFU. A mathematical model is derived, and a self-tuning fuzzy proportional-integral-derivative (PID) controller is designed and applied to control the welding current. The electrode wire feeding mechanism with this controller is driven by a DC motor, which can compensate for both the molten part of the electrode and undesirable fluctuations in the arc length during the welding process. By accurately maintaining the output welding current and welding voltage at constant values during the welding process, excellent welding results can be obtained. Simulation and experimental results are shown to prove the effectiveness of the proposed controller.
Phuc, Dang Vo Korean Mathematical Society 2020 대한수학회논문집 Vol.35 No.2
Let P<sub>s</sub> := 𝔽<sub>2</sub>[x<sub>1</sub>, x<sub>2</sub>, …, x<sub>s</sub>] = ⊕<sub>n⩾0</sub>(P<sub>s</sub>)<sub>n</sub> be the polynomial algebra viewed as a graded left module over the mod 2 Steenrod algebra, ${\mathfrak{A}}$. The grading is by the degree of the homogeneous terms (P<sub>s</sub>)<sub>n</sub> of degree n in the variables x<sub>1</sub>, x<sub>2</sub>, …, x<sub>s</sub> of grading 1. We are interested in the hit problem, set up by F. P. Peterson, of finding a minimal system of generators for ${\mathfrak{A}}$-module P<sub>s</sub>. Equivalently, we want to find a basis for the 𝔽<sub>2</sub>-graded vector space ${\mathbb{F}}_2{\otimes}_{\mathfrak{A}}$ P<sub>s</sub>. In this paper, we study the hit problem in the case s = 5 and the degree n = 5(2<sup>t</sup> - 1) + 6 · 2<sup>t</sup> with t an arbitrary positive integer.
Phuc Tran NGUYEN,Trinh Tuyet Thi PHAM 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.11
This article examines the role of financial development in economic growth in a number of transitional economies where the financial systems were newly established or reformed only in the early 1990s to facilitate their transition from centrally planned economies to marketbased ones. Based on a dataset collected from 29 transitional economies and 5 Asian developing economies covering the period 1990–2020, an empirical endogenous growth model is specified and estimated using the generalized method of moments (GMM). Three measures of financial development are used to investigate the relative role of the banking system and stock exchange market in the process of transition and growth. The results show that the three measures of financial development are crucial determinants of economic growth in transitional economies but the link seems to be in an inverted U-shape. This suggests the existence of thresholds for different channels of the financial sector to expand to positively influence growth. When becoming too large relative to the size of the economy, the financial system would have become a factor not conducive to growth. The growth convergence hypothesis is also confirmed and the impacts of other growth determinants are overall consistent with the extant literature.
Identification of Genome-wide SNPs by Genotyping by Sequencing in a Collection of Pear cultivars
Phuc Lam Nguyen,Sung-Chur Sim 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10
Cultivated pears (Pyrus spp.) are a major fruit crop with high nutritional value in the Rosaceae family. With next-generation sequencing technologies, single nucleotide polymorphisms (SNPs) have commonly been used to evaluated genetic variations in crop species. In this study, we collected 48 pear cultivars representing Asian pears (P. pyrifolia) and performed genotyping by sequencing (GBS) to discover genome wide SNPs. The Illumina HiSeq X sequencing of GBS library generated 774.1 million raw reads with an average length of 151 bp in the collection of pear cultivars. The length of trimmed reads was 105.1 Gb indicating 208x coverage of a pear reference genome assembly (504 Mb). A total of 412,766 confident SNPs was found across 17 pear chromosomes. Of these, a subset of 478 SNPs was filtered based on ≥ 0.3 of polymorphic information content (PIC), ≤ 15% of heterozygote rate, and physical distribution on each chromosome. This subset consisted of 326 SNPs from coding sequences and 152 SNPs for non-coding sequences. To develop a molecular tool for variety identification, the 478 SNPs were used to estimate both Nei’s and Euclidean genetic distances in the 48 pear cultivars. The dendrogram based on these genetic distances demonstrated that all of pear cultivars were differentiated using the SNP markers. This result suggests that the SNP resource from this study will be useful to develop a high-throughput DNA barcoding system for variety identification in cultivated pears.
Phuc, Chu Dac,Thuyet, Nguyen Minh,Kim, Jin-Chun The Korean Powder MetallurgyMaterials Institute 2020 한국분말재료학회지 (KPMI) Vol.27 No.6
Iron and copper are practically immiscible in the equilibrium state, even though their atomic radii are similar. As non-equilibrium solid solutions, the metastable Fe-Cu alloys can be synthesized using special methods, such as rapid quenching, vapor deposition, sputtering, ion-beam mixing, and mechanical alloying. The complexity of these methods (multiple steps, low productivity, high cost, and non-eco-friendliness) is a hinderance for their industrial applications. Electrical explosion of wire (EEW) is a well-known and effective method for the synthesis of metallic and alloy nanoparticles, and fabrication using the EEW is a simple and economic process. Therefore, it can be potentially employed to circumvent this problem. In this work, we propose the synthesis of Fe-Cu nanoparticles using EEW in a suitable solution. The powder shape, size distribution, and alloying state are analyzed and discussed according to the conditions of the EEW.
LKY-047: First Selective Inhibitor of Cytochrome P450 2J2
Phuc, Nguyen Minh,Wu, Zhexue,O, Yuseok,Lee, Jee-Hyun,Oh, Sangtaek,Song, Gyu-Yong,Liu, Kwang-Hyeon American Society for Pharmacology and Experimental 2017 Drug metabolism and disposition Vol.45 No.7
<P>Highly selective cytochrome P450 CYP2J2 (CYP2J2) inhibitors suitable for reaction phenotyping are currently not available. (7S)-(+)-(4-Nitro-phenyl)-acrylic acid, 8,8-dimethyl-2-oxo-6,7-dihydro2H, 8H-pyrano[ 3,2-g] chromen-7-yl-ester (LKY-047), a decursin derivative, was synthesized, and its inhibitor potencies toward CYP2J2 as well as other cytochrome P450 (P450) enzymes in human liver microsomes (HLM) were evaluated. LKY-047 was demonstrated to be a strong competitive inhibitor of CYP2J2-mediated astemizole O-demethylase and terfenadine hydroxylase activity, with K-i values of 0.96 and 2.61 mu M, respectively. It also acted as an uncompetitive inhibitor of CYP2J2-mediated ebastine hydroxylation with a K-i value of 3.61 mu M. Preincubation of LKY-047 with HLMs and NADPH did not alter inhibition potency, indicating that it is not a mechanism-based inhibitor. LKY-047 was found to be a selective CYP2J2 inhibitor with no inhibitory effect on other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A (IC50 > 50 mu M). These in vitro data support the use of LKY-047 as a selective CYP2J2 inhibitor with potential application in the identification of P450 isoforms responsible for drug metabolism in reaction phenotyping assays.</P>