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      • SSCISCOPUSKCI등재
      • KCI등재

        Questionnaire Survey on Current Red Blood Cell Transport and Storage in Korea for Reducing Wastage

        Park Mikyoung,Hur Mina,Kim Hahah,Oh Kyungmi,Kim Hyunmi,Song Young Hye,Ko Dae-Hyun,Chung Yousun 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.3

        Background: To ensure safe red blood cell (RBC) transfusion practice, it is important to comply with storage and transport requirements of RBC units. We conducted a comprehensive survey on the practice of RBC transport and storage to explore the awareness of and compliance with the 30-minute rule, the current status of RBC unit transport, and possible utility of temperature indicators (TIs) to reduce RBC wastage. Methods: From June to August of 2019, 64 blood bank physicians (14 questions) in 64 secondary- and tertiary-care hospitals and 673 nurses (13 questions) in 42 tertiary-care hospitals replied to a questionnaire survey. The results of the survey were analyzed with descriptive statistics. Results: Among the physicians surveyed, 97.0% (N=62) of hospitals had transfusion guidelines in place. The RBC wastage in 2018 ranged from less than five units to more than 200 units. Among the nurses surveyed, 99.4% (N=669) were aware of and complied with the 30-minute rule; 13.5% (N=91) of the nurses had experience of RBC wastage due to violation of the 30-minute rule. Both physicians (67%, N=43) and nurses (83.1%, N=559) responded that TIs would help reduce RBC wastage. Conclusions: This is the first survey on the practices related to RBC transport and storage in Korea. This study provides fundamental data on current practice for the blood cold chain, insights into RBC wastage, and highlights the utility of TIs.

      • KCI등재

        Prognostic Utility of Procalcitonin, Presepsin, and the VACO Index for Predicting 30-day Mortality in Hospitalized COVID-19 Patients

        Park Mikyoung,Hur Mina,Kim Hanah,Lee Chae Hoon,Lee Jong Ho,Lee Jong Ho,Nam Minjeong 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.4

        Background: Biomarkers and clinical indices have been investigated for predicting mortality in patients with coronavirus disease (COVID-19). We explored the prognostic utility of procalcitonin (PCT), presepsin, and the Veterans Health Administration COVID-19 (VACO) index for predicting 30-day-mortality in COVID-19 patients. Methods: In total, 54 hospitalized COVID-19 patients were enrolled. PCT and presepsin levels were measured using the Elecsys BRAHMS PCT assay (Roche Diagnostics GmbH, Mannheim, Germany) and HISCL Presepsin assay (Sysmex, Kobe, Japan), respectively. The VACO index was calculated based on age, sex, and comorbidities. PCT and presepsin levels and the VACO index were compared using ROC curve, Kaplan–Meier method, and reclassification analysis for the 30-day mortality. Results: ROC curve analysis was used to measure PCT and presepsin levels and the VACO index to predict 30-day mortality; the optimal cut-off values were 0.138 ng/mL for PCT, 717 pg/mL for presepsin, and 12.1% for the VACO index. On Kaplan–Meier survival analysis, hazard ratios (95% confidence interval) were 15.9 (4.1-61.3) for PCT, 26.3 (6.4-108.0) for presepsin, and 6.0 (1.7-21.1) for the VACO index. On reclassification analysis, PCT and presepsin in addition to the VACO index significantly improved the prognostic value of the index. Conclusions: This study demonstrated the prognostic utility of measuring PCT and presepsin levels and the VACO index in COVID-19 patients. The biomarkers in addition to the clinical index were more useful than the index alone for predicting clinical outcomes in COVID-19 patients.

      • Analysis of Pulse Waves Measured on Three Regions of Radial Artery According to Korean Traditional Medicine

        Mikyoung Park,Eungeun Kim,HeeJung Kang,Young Huh 대한전자공학회 2007 ITC-CSCC :International Technical Conference on Ci Vol.2007 No.7

        The objective of this study was to examine the changes of the pulse waves according to three regions of radial artery. In Korean traditional medicine, the pulse shape of three regions of radial artery can give different information about the patient’s health condition. Therefore we examined the characteristics of pulse wave measured on each region. Fifty one subjects participated in this study. One region was designated at radial bone and two regions were designated 1cm apart from it. Applied pressure, energy, period, amplitude of first peak and first valley, amplitude of second peak and second valley, amplitude of third peak, time to first peak and first valley, time to second peak and second valley, time to third peak, systolic duration, diastolic duration and area of pulse waves were analyzed. P-values of applied pressure, energy, amplitude of first peak, amplitude of second peak, amplitude of second valley, time to first peak, time to second peak and area of pulse wave were less then the significance level of 0.05. Therefore we could conclude that the pulse wave obtained from three regions of radial artery had different characteristics. This preliminary study showed that we should designate exact position before pulse wave analysis.

      • KCI등재

        Current Status of Flow Cytometric Immunophenotyping of Hematolymphoid Neoplasms in Korea

        Park Mikyoung,Lim Jihyang,Ahn Ari,Oh Eun-Jee,Song Jaewoo,Kim Kyeong-Hee,Han Jin-Yeong,Choi Hyun-Woo,Park Joo-Heon,Shin Kyung-Hwa,Kim Hyerim,Kim Miyoung,Hwang Sang-Hyun,Kim Hyun-Young,Cho Duck,Kang Eun 대한진단검사의학회 2024 Annals of Laboratory Medicine Vol.44 No.3

        Background: Flow cytometric immunophenotyping of hematolymphoid neoplasms (FCI-HLN) is essential for diagnosis, classification, and minimal residual disease (MRD) monitoring. FCI-HLN is typically performed using in-house protocols, raising the need for standardization. Therefore, we surveyed the current status of FCI-HLN in Korea to obtain fundamental data for quality improvement and standardization. Methods: Eight university hospitals actively conducting FCI-HLN participated in our survey. We analyzed responses to a questionnaire that included inquiries regarding test items, reagent antibodies (RAs), fluorophores, sample amounts (SAs), reagent antibody amounts (RAAs), acquisition cell number (ACN), isotype control (IC) usage, positive/negative criteria, and reporting. Results: Most hospitals used acute HLN, chronic HLN, plasma cell neoplasm (PCN), and MRD panels. The numbers of RAs were heterogeneous, with a maximum of 32, 26, 12, 14, and 10 antibodies used for acute HLN, chronic HLN, PCN, ALL-MRD, and multiple myeloma-MRD, respectively. The number of fluorophores ranged from 4 to 10. RAs, SAs, RAAs, and ACN were diverse. Most hospitals used a positive criterion of 20%, whereas one used 10% for acute and chronic HLN panels. Five hospitals used ICs for the negative criterion. Positive/negative assignments, percentages, and general opinions were commonly reported. In MRD reporting, the limit of detection and lower limit of quantification were included. Conclusions: This is the first comprehensive study on the current status of FCI-HLN in Korea, confirming the high heterogeneity and complexity of FCI-HLN practices. Standardization of FCI-HLN is urgently needed. The findings provide a reference for establishing standard FCI-HLN guidelines.

      • Investigations on IT/ET and IT/BT Convergence Technology Using Power Line Communications

        Mikyoung Park(박미경),Young Huh(허영),Sang Ki Oh(오상기) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.10

        Due to enhanced high IT (information technology) development, IT-based technology convergences such as IT/ET(electric technology), IT/BT(biology technology) and IT/NT(nano technology) are actively merging trend and their applications spread wide. In this paper PLC (power line communication), one of the merging IT, is investigated as one of the potential IT candidates for IT/ET and IT/BT convergence technology for DLC (direct load control) or bio-medical engineering such as ubiquitous health cares or D2H2 (distributed diagnosis and home health care).

      • KCI등재

        국제형사재판소(ICC)의 ‘범행지배이론’에 대한 고찰

        박미경(PARK Mikyoung) 대한국제법학회 2015 國際法學會論叢 Vol.60 No.4

        핵심범죄에 대한 ‘개인의 형사책임’의 개념은 국제형사법 상 매우 중요하다. 일반적으로 국제법상 가장 중대한 범죄라고 여겨지는 ICC의 핵심범죄는 개인이 단독으로 실행하는 경우가 거의 없고, 조직 속에서 주로 저질러진다. 즉, 국가권력이나 이와 유사한 강력한 조직인 군대나 무장집단을 배경으로 그 정책의 일환으로써 복수의 가담자에 의해서 저질러지는 것이 국제법상 핵심범죄의 특징이라고 할 수 있다. 그러므로 핵심범죄의 모든 가담자의 형사책임을 적절하게 추궁하기 위해서는 범죄에 있어 실질적인 역할 분담이 어떻게 이루어져 있는지, 그 역할과 정도를 어떻게 판단해야 하는지가 중요한 부분을 차지한다. 더 나아가 이러한 올바른 판단기준의 설정은 결국 ‘개인의 형사책임’원칙이 적절히 구현되고 있는지와 관계되어 있기 때문에 국제형사법상 중요한 과제라고 할 수 있다. 본 논문은 이러한 점들에 근거하여 ICC에서 핵심범죄를 저지른 ‘개인의 형사책임’이 어떻게 추궁되고 있는지에 대해 분석하였다. ICC는 ‘개인의 형사책임’을 추궁하는 데 있어 범죄에 대한 지배ㆍ통제(control over crime), 즉 범행지배이론(control-theory)을 새롭게 적용하고 있다. ICC의 ‘범행지배이론’은 정범의 책임을 추궁할 때 조직적 지배 구조의 특징도 반영하였기 때문에 적극적으로 상급자의 책임을 추궁할 수 있을 뿐만 아니라, ICTY가 ‘개인의 형사책임’을 추궁하기 위해 도입하였던 JCE(Joint Criminal Enterprise) 이론보다 엄격한 귀책판단을 가능하게 하는 법리로 평가받고 있다. 본 논문에서는 ‘범행지배이론’을 검토하기 위해 ICC의 판례들을 분석하면서 동 이론의 개념과 구성요건 등에 대해 설명하고 그 발전과정과 주요 내용을 살펴본다. 그리고 ‘범행지배이론’과 JCE이론의 내용을 비교한 후 ICC의 판례에서 지적되었던 비판을 중심으로 ‘범행지배이론’에 대해 검토한다. The concept of ‘individual criminal responsibility’ for core crimes is very important in the International Criminal Law. In general, the core crimes of International Criminal Court (ICC) that are regarded as the most serious crimes are hardly committed by an individual independently but committed mainly in organizations. In other words, the characteristics of the core crimes in the international law are that the crimes are committed by a plural number of participants as part of policies of the army or armed groups which are similar to the power of the state or similar powerful organizations. Therefore in order to appropriately interrogate the criminal responsibility of all the participants in the core crimes, it is important to grasp who did what actually in the crime and how the roles and the extents in the crime should be judged. Moreover, since the establishment of the right judgment criteria is related to whether or not the ‘individual criminal responsibility’ principle are appropriately realized, it is an important task in the International Criminal Law. Based on these points, this thesis analyzed how the ‘individual criminal responsibility’ for committing core crimes in ICC is interrogated. ICC newly applies ‘control over crime’, i.e. the ‘control-theory’ in interrogating the ‘individual criminal responsibility’. Since the ‘control-theory’ of ICC reflects the characteristics of organizational governance structure when interrogating the responsibility of the leaders it not only can interrogate the seniors aggressively but also is evaluated as the legal principle that enables stricter imputation judgment than the ‘Joint Criminal Enterprise’ (JCE) that ICTY introduced to interrogate ‘individual criminal responsibility’. This thesis analyzes the precedents of ICC to examine the ‘control-theory’ and explains the concept and elements of the theory and examines its process of development and main contents. And after comparing the ‘control-theory’ with the JCE, and the ‘control-theory’ is examined focusing on the criticism pointed out in the precedents of ICC.

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