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      • Visual Motor Potentials Based Brain-Computer Interface Communication for Cursor Tracking

        Ou BAI,Masatoshi NAKAMURA,Hiroshi SHIBASAKI 한국과학기술원 인간친화 복지 로봇 시스템 연구센터 2001 International Journal of Assistive Robotics and Me Vol.2 No.3

        The Brain-Computer Interface (BCI) is a communication system providing new augmentative communication technology to patients with neuromuscular impairments. The BCI system will "bypass" the damaged motor pathway of a paralyzed individual by interfacing his motor cortex directly with a computer. In this paper, we report a preliminary result of the development of BCI system using visual responses of motor potentials (MP s) achieved in our laboratory. This work includes the design and construction of a BCI system for the measurement and recording the MP s under the visual stimulation generated from a moving target, and the analysis of the relationships between the recorded MP s and the motion of the moving target. The analytical results say that the moving direction of a target can be directly recognized by computer based on the generated MP s from the visual stimulation. Because of the good signal-to-noise ratio of the visual MP s, the visual MP s based BCI method enable a higher communication speed than that of other BCI methods. The applications of the visual MP s based communication are also discussed.

      • KCI등재후보

        Possible Applications for Fascial Anatomy and Fasciaology in Traditional Chinese Medicine

        Yu Bai,소광섭,Byung-Cheon Lee,Yong Huang,Chun-lei Wang,Jun Wang,Jin-peng Wu,Jing-xing Dai,Janos Palhalmi,Ou Sha,David Tai Wai Yew,Lin Yuan 사단법인약침학회 2010 Journal of Acupuncture & Meridian Studies Vol.3 No.2

        Research using medical imaging instruments such as computed tomography and magnetic resonance imaging has led to the proposal that the fascial network distributed over the human body is the anatomical basis for the acupoints and meridians of traditional Chinese medicine. Therefore, we put forward a new theory of anatomy called fascial anatomy. In fascial anatomy, a human body is divided into two major systems. One is the supporting-storing system of unspecialized connective tissues. The other is a functional system. An undifferentiated non-specific connective tissue network, with the participation of the nervous and the immune systems, constitutes the supporting-storing system of the human body. The various differentiated functional cells in the body that are supported and surrounded by the supporting-storing system constitute the functional system. The discipline that studies the supporting-storing system and the mutual relationship between this system and the functional system in a living human body is called fasciaology. The establishment of fascial anatomy and fasciaology opens a new research field in anatomy; consequently, fasciaology will play a significant role in biological medicine and traditional Chinese medical research, as well as future clinical practice.

      • Micronucleus Expression and Acute Leukemia Prognosis

        Wang, Run-Chao,Yang, Lei,Tang, Yang,Bai, Ou Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

        The micronucleus frequency (MNF) in peripheral blood lymphocytes (PBL) is a biomarker of chromosomal damage and genome instability in human populations.The relationship of micronucleus frequency with prognosis of patients with acute leukemia is not clear. We therefore investigated MNF in mitogen-activated peripheral blood lymphocytes from patients with hematologic diseases and solid tumours. Patients included 50 with acute leukemia, 49 diagnosed with myelodysplastic syndrome (MDS), 54 with benign blood diseases, and 45 with solid tumours, examined with 50 healthy controls. The mean MNF was significantly higher in cases of hematologic diseases and solid tumor patients than in healthy controls (P<0.001). There was no evident difference between MNF in the acute leukemia ($7.15{\pm}2.18$) and solid tumor groups ($7.11{\pm}1.47$), but both were higher than in the MDS group ($5.12{\pm}1.29$) and benign blood diseases group ($3.08{\pm}1.08$). Taking 7.15‰, the average MNF of the acute leukemia group as standard, and dividing 50 cases of acute leukemia patients into high MNF group ($MNF{\geq}7.15$‰) and low MNF group (MNF<7.15‰). The overall response (complete remission + partial remission) rates of the low MNF group were significantly higher than in the high MNF group (P=0.001). The high MNF group further showed lower overall survival rates than the low MNF group. MNF expression and progression-free survival seemed to have a opposite relationship, with a correlation coefficient of -0.702. These data indicate that MNF in peripheral blood lymphocytes is important for evaluation of prognosis of acute leukemia patients, and it can reflect progression of disease to a certain degree.

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        Effects of Temperature Distribution on Microstructure and Mechanical Properties of Hot Extruded Al–Zn–Mg–Cu Alloy Pipe with Variable Cross-Section

        Lei Luo,Zhiyi Liu,Song Bai,Jing Cao,Fei Liu,Linnan Ou,Juangang Zhao 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

        The microstructures and mechanical properties of a hot extruded Al–Zn–Mg–Cu alloy pipe with variable cross-section areinvestigated by transmission electron microscopy, electron backscattering diffraction, hardness testing and finite elementmethod. The results suggest that the variable temperature distribution at different positions along the extrusion directionafter hot extrusion attribute to the changes in hot deformation degrees. The extruded profile at billet temperature of 410 °Cand a ram speed of 1.5 mm/s shows a gradual increase in temperature from 416 to 467 °C at strains from 3.7 to 8.6 alongthe extrusion direction. The dynamic recovery (DRV) and partial dynamic recrystallization (DRX) are observed in the hotextruded profile, and high-angle grain boundaries fraction exponentially rises along the extrusion direction. The hardnessat different positions of the hot extruded profile shows a nearly exponential decline along the extrusion direction, mainlyascribes to the decrease of the dislocation density that caused by the dynamic softening.

      • Clinical Analysis of Stages of HBV Infection in 100 Cases of Lymphoma

        Tang, Yang,Sun, Li-Guang,Liu, Chun-Shui,Li, Yu-Ying,Jin, Chun-Hui,Li, Dan,Bai, Ou Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Objective: HBV infection may cause damage to the immune system and induce lymphomas as a result. Some scholars have indicated that HBsAg(+) reflecting HBV infection may have a relationship with lymphoma development. This study was designed to find out the specific stage of HBV infection which may be related to lymphoma. Methods: HBV serum markers, including HBsAg, HBsAb, HBeAg, HBeAb, HBcAb were tested among 100 lymphoma patients and 100 other patients who were diagnosed with non-lymphoma diseases in the First Hospital of Jilin University from 2010.1.1 to 2012.12.31. Three subgroups were established depending on different combinations of HBV serum markers. Subgroup 1 was HBsAg(+) representing the early stage of HBV infection. Subgroup 2 was HbsAb(+) representing convalescence and Subgroup 3 was "HbsAg and HbsAb negative combined with other positive markers" representing the intermediate stage of HBV infection. Chi square tests were used to compare the rates of three subgroups in lymphoma and control groups. Results: The rates of Subgroup were 13% and 5% respectively, an association between HBsAg and lymphoma being found (P<0.05). There was no difference between rate of Subgroup 2 of lymphoma group (15%) and that of control group (16%). In lymphoma group and control group, the rate of Subgroup 3 was different (12% vs 4%). This evidence was not specific to T cell lymphoma, B cell lymphoma or Hodgkin's lymphoma. Conclusions: Among serum markers of HBV, the combination of serum markers representing the early stage and intermediate stage of HBV infection have a relationship with lymphoma. Convalescence from HBV infection appears to have no relationship with lymphoma.

      • KCI등재후보

        Correlations Between Fasciology and Yin Yang Doctrine

        Hui Tao,Mei-chun Yu,Hui-ying Yang,Rong-mei Qu,Chun Yang,Xin Zhou,Yu Bai,Jing-peng Wu,Jun Wang,Ou Sha,Lin Yuan 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.2

        The aim of this study is to explore the correlations between fasciology and yin yang doctrine. Professor Yuan developed fasciology by three-dimensional reconstruction of connective tissue (fascia) in the trunk and limbs of the human body and tracing back to tissue origins in light of biological evolution and developmental biology. Fasciology states that the human body can be divided into two systems: the supporting-storing system and the functional system. This article elaborates on the roles of the two systems and their mutual relationship. The two systems are used to analyze the yin,the yang, and their relationship. The two systems are promoted but also restricted in different contexts. The supporting-storing system is formed by undifferentiated connective tissue and provides undifferentiated cells and nutrients for differentiated cells of the functional system. Thus, the supporting-storing system could be classified as quiet, similar to yin. The functional system continuously maintains the various functional activities of the human body. Thus, the functional system could be classified as active, similar to yang. In interpreting the yin yang doctrine from the point of view of fasciology, yin can be compared with the supporting-storing system and yang can be compared with the functional system.

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