포도상구균 폐렴을 동반한 고면역글로불린 E 증후군 1례

오흥원,서원석,신상만 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

The hyperimmunoglobulin E syndrome is a rare primary immunodeficiency disorder characterized by extremely high serum IgE levels and eosinophilia, and serious recurrent bacterial infections of the skin and sinopulmonary tract in early life. Associated clinical features are coarse facial appearance and chronic eczematoid dermatitis. The most common organism that infect these patients are S. aureus and C. albicans. The patients' serum IgE levels are elevated but the basic immunologic mechanism is not fully understood. It is believed that the elevated IgE levels reflect a T-cell imbalance characterized by T-cell activation and a deficiency of suppressor T cells to inhibit IgE production. We have experienced a case of hyperimmunoglobulin E syndrome in a ??-year-old boy who had suffered from recurrent staphylococcal pneumonia and onychomycosis and chronically pruritic dermatitis from 3 months of age with elevated serum IgE level. A brief review of the related literature is presented.

치수에서 Eugenolol iCGRP(immunoreactive calcitonin gene-related peptide)의 분비조절에 미치는 영향

오원만,최남기,김선헌 大韓齒科保存學會 1999 Restorative Dentistry & Endodontics Vol.24 No.1

인공타액 오염이 수종 상아질접착제와 상아질간의 결합에 미치는 영향

오원만,양규호,류미애 大韓齒科保存學會 1992 Restorative Dentistry & Endodontics Vol.17 No.2

The purpose of this study was to evaluate the influence of artificial saliva contamination on bonding of several dintin adhesives to dentin. Sixty-three human molar teeth extracted within a month were used. Each tooth was sectioned longitudinally in a buccolingual direction to obtain 126 wpecimens. These specimens were randomly divided into three froups and were treated by Scotchbond 2, Gluam and All vond. Each group was subdivided into three subgroups; normal group not contaminated with artificial saliva, contaminated with artificial saliva and dried group, and contaminated with artificial saliva and washed and dried group. Enamel/dentin bonding agent (Dental Adhesive of Scotchbond 2) was applied light cured on the treated dentin surfaces. Threrafter P-50 were cured on them, and specimens were storde in 37℃ artificial saliva for 24 hours before measuring shear bond strength. Shear bond strengths were determined using an universal testing machine with cross head speed 1mm/min and SEM examinations were conducted to evaluate the resin-dintin interface and degree of penetrating resin string into the dentinal tubules. The following results were obtained. 1. Normal gropqs ont contaminated with artificial saliva showed greater shear bond streagth than any other group contaminated with artificial saliva)P<0.01). 2. The shear bond strengths showed no significant difference between washed groups with distilled water and ont washed groups after contamination with artificial saliva(P>0.05). 3. In normal groups, the shear bond strength of A group was significantly greater than in any other group(P<0.01). 4. In S and G groups, fractrues after shear bond strength tests occured adhesively on resintooth interface in all specimens. But in A groups, fractrue of the normal group occured cohesively in dentin and fractrue of the contaminated groups coourde adhesively and cohesively. 5. On SEM examination, the number of resin strings penotrated into dentinal tubules were the greatest in normal groups, followed by, in descending oredr, wasghed groups and not washed groups after contamination with artificial saliva.

탈회골기질 이식에 대한 치수세포의 반응에 관한 실험적 연구

오원만,김민선,김선헌 大韓齒科保存學會 1995 Restorative Dentistry & Endodontics Vol.20 No.2

백서 척수에서 Capsaicin과 Eugenol이 iCGRP (immunoreactive calcitonin gene-related peptide) 분비 조절에 미치는 영향

오원만,김원재,최남기,박상원,황인남,김선현 大韓齒科保存學會 2001 Restorative Dentistry & Endodontics Vol.26 No.5

Neuropeptide such as calcitonin gene-related peptide and substance P may mediate neurogenic inflammation, but little is known about the regulation of neuropeptide release from rat spinal cord. Eugenol has been reported to reduce odontogenic pain and is known to have a structure similar to capsaicin, a potent stimulant of certain nociceptors. This study was done to examine the effect of capsaicin and eugenol on immunoreactive calcitonin gene-related peptide (iCGRP) release from rat spinal cord and whether eugenol regulates capsaicin-sensitive release of iCGRP or it evokes capsaicin-sensitive release of iCGRP. The dorsal half of rat lumbar spinal cord was chopped into 200㎛ slices. They were superfused (500㎕/min) in vitro with an oxygenated Kreb's buffer. The EC50 of capsaicin on iCGRP release was measured. Eugenol (600㎛ and 1.2mM) and vehicle (0.02% 2-hydroxyl-β-cyclodextrin) were administered prior to stimulation of rat lumbar spinal cord with capsaicin. The amount of iCGRP release from rat lumbar spinal cord was measured by radioimmunoassay. The results were as follows : 1.iCGRP release from rat lumbar spinal cord was dependent on concentration of capsaicin. The EC50 of capsaicin on iCGRP release was 3㎛. 2.In the vehicle treated group, capsaicin (3㎛) evoked a 14-fold increase over basal iCGRP level. 3. Administration of 600㎛ and 1.2mM eugenol evoked a 2.2-fold increase and a 2.3-fold increase over basal iCGRP level respectively. 4.Administration of 600㎛ and 1.2mM eugenol increased capsaicin evoked release of iCGRP by more than 50%. These results indicate that eugenol evoke CGRP release from central nervous system and potentiate the pain-inducing action of capsaicin on it Key words : Eugenol, Capsaicin, Rat lumbar spinal cord, Superfusion, Radioimmunoassay

치과용 심미 수복 재료들의 색상 연구를 통한 새로운 치과용 색체계의 제안

오윤정,박수정,김동준,조현구,황윤찬,오원만,황인남 대한치과보존학회 2007 Restorative Dentistry & Endodontics Vol.32 No.1

본 연구는 새로운 치과용 색체계 개발을 목적으로 현재 치과에서 사용되고 있는 Vita shade를 사용하는 9 제조사의 12종의 광중합형 복합레진과 1종의 치과용 도재의 색상을 diffuse/8° 수광 방식을 사용하는 분광색체계 (MiniScan XE plus, Model 4000S, Hunter Lab, USA)를 이용해 D65 표준광과 10도 관찰자 시야 하에서 CIE L^(*)a^(*)b^(*) 값을 측정하고 색상 범위를 분석하였다. 분석한 정보를 color sorting system을 응용한 CNU Cons Dental Color Chart의 색상 표현 방식인 T###에 치과용 수복 재료들의 범위를 적용하여 다음의 결과를 얻었다. 측정된 L^(*)a^(*)b^(*)값의 분포를 분석해 보면 L^(*)값은 80.40과 52.70 사이에, a^(*)값은 10.60과-3.60 사이에, 그리고 b^(*)값은 28.40과 2.21 사이에 분포한다. L^(*)값의 평균값은 67.40, 중앙값은 67.30이며, a^(*)값은 2.89와 2.91, b^(*)값은 14.30 과 13.90 이다. 이러한 분석을 토대로 CNU Cons Dental Color Chart의 T###의 첫 번째 숫자에 해당하는 L^(*)값의 각 숫자간의 차이는 2.0으로, 그리고 2번째 숫자인 a^(*)값의 각 숫자간의 차이는 1, 그리고 세 번째 숫자인 b^(*)값의 각 숫자간의 차이는 2로 정하였다. T555에 해당하는 L^(*)값의 범위는 66.0이상, 68.0미만으로, a^(*)값의 범위는 3이상 4미만으로, b^(*)값의 범위는 14이상 16미만으로 결정하였다. The purpose of this study is to develope new dental color-space system. Twelve kinds of dental composites and one kind of dental porcelain were used in this study. Disk samples (15 ㎜ in diameter, 4 ㎜ in thickness) of used materials were made and sample’s CIE L^(*)a^(*)b^(*) value was measured by Spectrocolorimeter (MiniScan XE plus, Model 4000S, diffuse/8° viewing mode, 14.3 ㎜ Port diameters, Hunter Lab. USA). The range of measured color distribution was analyzed. All the data were applied in the form of T### which is expression unit in CNU Cons Dental Color Chart. The value of L^(*) lies between 80.40 and 52.70. The value of a^(*) are between 10.60 and 3.60 and b^(*) are between 28.40 and 2.21. The average value of L^(*) is 67.40, and median value is 67.30. The value of a^(*) are 2.89 and 2.91 respectively. And for the b^(*), 14.30 and 13.90 were obtained. The data were converted to T### that is the unit count system in CNU-Cons Dental Color Chart. The value of L^(*) is converted in the first digit of the numbering system. Each unit is 2.0 measured values. The second digit is the value of a^(*) and is converted new number by 1.0 measured value. For the third digit b^(*) is replaced and it is 2.0 measured unit apart. T555 was set to the value of L^(*) ranging from 66.0 to 68.0, value of a^(*) ranging from 3 to 4 and b^(*) value ranging from 14 to 16.

초기 방습이 글래아이오노머 시멘트의 색안정성 및 투명도 변화에 미치는 영향

오원만,김선헌,정선와 大韓齒科保存學會 1994 Restorative Dentistry & Endodontics Vol.19 No.1

광중합 복합레진의 색안정성 및 투명도 변화에 관한 가속시험

황인남,오원만 大韓齒科保存學會 1993 Restorative Dentistry & Endodontics Vol.18 No.1

AbstractColor stability of tooth colored restorative resins is an important factor, particularly in anterior teeth restoration.The purpose of this study was to evaluate the color stability and opacity change of several light curing composite resins. Specimens of eight composite resins(Prisma AP. H., Brilliant Enamel, Charisma, Durafil, Helio Progress, Herculite XR, P-50 and Silux Plus) were divided into two groups '?In Group 1, the specimens were polymerized by visible light curing unit for 60 seconds on both sides and in Group 2, the post-cured specimens were heat tempered by light/heat curing unit for 45 units(about 18 min.). All specimens were stored in distilled water at 60? for 30 days.The color characteristics(L*, a*, b*) and opacity of the specimens before and after immersion were measured by spectrocolorimetry and the total color difference (AE*) and opacity change (AY%) were computed.The results obtained were as follows : 1. SP and APH in both groups, DF, HP and HXR in Group 1 showed AE*-value above 2.0. 2. DF, HP, SP and HXR in Group 1 showed higher AE*-value than in Group 2, but the others had no significant difference. 3. The opacity of CH and HXR in Group 1, and of CH and BE in Group 2 decreased after immersion, while that of the others increased. 4. Opacity change of BE, P50 and HXR was significantly different between Group 1 and 2. These results suggest that color change in the post-cure heat tempered specimens by li- ght/heat curing unit was smaller than that of the specimens polymerized by visible light curing unit. No clinically detectable opacity changes were noted for any materials in either goup.

파노라마방사선사진에서 석회화가 발견되는 경동맥의 협착 정도

조소양,오원만,윤숙자,윤웅,이재서,Juan M. Palomo,강병철 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.3

Purpose : This study aimed to investigate the luminal stenosis of the internal carotid artery with calcification detected on panoramic radiographs. Materials and Methods : This study used fifty carotid arteries of 36 dental patients whose panoramic radiograph and computed tomography angiography (CTA) revealed the presence of carotid artery calcification. A neuroradiologist interpreted CTA to determine the degree of stenosis of the internal carotid arteries. The degree of stenosis was stratified in four stages; normal (no stenosis), mild stenosis (1-49%), moderate stenosis (50-69%) and severe stenosis (70-99%). Results : Among the fifty carotid arteries with calcification detected on both panoramic radiography and CTA, 20 carotid arteries (40%) were normal, 29 carotid arteries (18%) had mild stenosis, 1 carotid artery (2%) had moderate stenosis, and there was none with severe stenosis. Conclusion : Sixty percent of the carotid arteries with calcification detected on both panoramic radiography and CTA had internal luminal stenosis, and two percent had moderate stenosis. When carotid atheroma is detected on panoramic radiograph, it is possible that the dental patient has luminal stenosis of the internal carotid artery. (Korean J Oral Maxillofac Radiol 2009; 39 : 157-61)

Pulsed Nd:YAG 레이저 조사에 의한 상아질의 온도변화에 대한 연구

김영일,오원만 전남대학교 치과대학 1995 전남치대논문집 Vol.7 No.1

This study was performed to evaluate the possibility of pulpal damage by measuring temperature change occured in dentin according to the thickness of dentin, the time of irradiation and the output of laser energy when the dentin surfaces were irradiated with Nd-YAG laser under water coolant and no water coolant. Sound upper and lower molar teeth were sectioned with 1mm, 1.5mm and 2.0mm thickness of dentin discs and divided into 3 groups by dentin thickness. 0.5 watt, 1 watt, 1.5 watt and 2.0 wattenergied beam of pulsed 10 p.p.s of Nd : YAG laser was applied respectively to dentin surfaces for 8 secs and 16 secs when water coolant is used or not. And then the temperature changes occured in dentin were measured at opposite surfaces of laser-irradiated dentin surfaces with digital thermometer. The results were as follows. 1. When the amount of irradiated energy was same, the temperatue changes of dentin were higher as the thickness of dentin discs was thinner (p<0.01). 2. When the amount of irradiated energy and the thickness of dentin were same, the temperature changes of dentin were lower under water coolant than under no water coolant in all groups (p<0.01). 3. With the increase of time of irradiation, the temperature changes of Dentin became higher in all groups and were steeply increased at initial period of irradiation of laser. 4. Under the same thickness of dentin, the temperature changes of dentin became higher as irradiated energy was increased. These results suggest that when the beam of Nd : YAG Laser is irradiated to dental hard tissue, amount of irradiating energy, thickness of dentin, using water coolant must be considered in order to minimize thermal damage of the pulp.