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Noriko Nakamura,Yuichi Yamashita,Shinichi Tanihara,Chiemi Maeda 대한의료정보학회 2014 Healthcare Informatics Research Vol.20 No.3
Objectives: The aim of this study was to evaluate the effectiveness and sustainability of educational interventions to encourage incident reporting. Methods: This was a quasi-experimental design. The study involved nurses working in two gastroenterology surgical wards at Fukuoka University Hospital, Japan. The number of participants on each ward was 26 nurses at baseline. For the intervention group, we provided 15 minutes of education about patient safety and the importance of incident reporting once per month for six months. After the completion of the intervention, we compared incident reporting in the subsequent 12 months for both groups. Questionnaires about reasons/motives for reporting were administered three times, before the intervention, after the intervention, and six months after the intervention for both the intervention group and the control group. Results: For the intervention group, incident reporting during the 6 months after the intervention period increased significantly compared with the baseline. During the same period, the reasons and motives for reporting changed significantly in the intervention group. The increase in reported incidents during the 6- to 12-month period following the intervention was not significant. In the control group, there was no significant difference during follow-up compared with the baseline. Conclusions: A brief intervention about patient safety changed the motives for reporting incidents and the frequency of incidents reported by nurses working in surgical wards in a university hospital in Japan. However, the effect of the education decreased after six months following the education. Regular and long-term effort is required to maintain the effect of education.
완전통합교육론과 저출현 장애아교육의 모순 -미국 시각장애아 교육의 관점에서-
중촌만기남 ( Nakamura,Makio ),강전자 ( Oka,Noriko ),조원일 ( Won Il Cho ) 한국특수교육문제연구소 2005 특수교육저널 : 이론과 실천 Vol.6 No.2
통합교육이 완전통합에 이른 단계에서 그 이념에 반하여 장애 마이너리티가 생기게 되었다. 본 논문에서는 완전통합론을 창도한 이들이 최대의 문제로 삼은 분리 내지 격리와 그 관련 문제를 중심으로 그들이 무엇을 달성하려 하였는지에 대해 장애 마이너리티의 전형으로서 시각장애의 관점에서 검토했다. 완전통합에서는 특수교육과는 다른 대상론을 갖고, 장애에 따른 독특한 요구와 분리적 환경에서의 교육에 대해서는 대개 부정적이며, 분리를 통해 정치적으로 인종차별을 연상케 하였다. 또한 완전통합론에서 분리를 부정하고 특수교육의 해소를 지향한 것은 분리가 민주제 사회로의 완전참가를 저해한다고 생각했기 때문이었다. 완전통합론자가 효율성을 문제로 삼은 것은 한정된 자원의 유효한 배분이라는 발상에서였다. 그러나 완전통합론의 보편적 이념과 각 장애의 개별의 요구가 정합되지 않는 점으로부터 시각장애 등에서는 완전통합의 이념에 반하는 결과가 발생하였다. In the stage to which inclusion movement has evolved full inclusion, the disability minority group such as visual or auditory impairment that it attempted to eliminate has appeared. So, it is required to reexamine the principles that the inclusion advocates consider as important. In this paper, it is made clear from standpoint of blindness as a typical disability minority group what full inclusionists will attain through criticisms of segregation and its related matters. In full inclusion, it had a different subject theory from special education. full inclusionists insist that separation means racial segregation politically. Moreover, full inclusionists tended to deny separation and special education, because it thought that separation impedes the full participation of people including the disabled to democracy society and construction of democratic society as their last purpose. full inclusionists consider as a problem the efficiency issue of special education from the standpoint of effective distribution of the limited resources. However, since the universal idea of full inclusion and the individual needs of each disability were not adjusted, the results contrary to the idea of full inclusion arose in the disability minority such as the visual impairment.
Toshio Nakamura,Haruo Yamamura,박경호,Caroline Pereira,Yoshikazu Uchida,Noriko Horie,김무조,Satoshi Itami 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7
Alopecia is divided into two categories: androgenic alopecia and nonandrogenic alopecia. An androgen-dependent abnormality of biological functions causes alopecia in males, but the role of androgens is not yet elucidated in female pattern hair loss (FPHL). Modulation of androgenic activity is not effective in certain kinds of androgenic alopecia in females, as well as in cases of nonandrogenic alopecia in males and females. The hair growth drug, minoxidil, stimulates vascular endothelial growth factor (VEGF) production as well as vascularization and hair growth in females. Yet, because minoxidil has side effects with long-term use, a safe alternative hair growth agent is needed. Whereas hair develops after birth in mammalian species, hair mostly grows in a precocial bird, in the chicken, between hatching days 14 and 15. Therefore, we hypothesized that the chicken egg contains a key hair growth factor. In this study, we demonstrated that water-soluble peptides derived from the egg yolk stimulate VEGF production and human hair follicle dermal papilla cell growth. We also found that these peptides enhance murine hair growth and improve hair growth in FPHL. Finally, we characterized that water-soluble egg yolk peptides induce VEGF expression through insulin growth factor-1 receptor activation-induced hypoxia-inducible factor-1α transcription pathway. We have given the name “hair growth peptide (HGP)” to this water-soluble egg yolk peptide.
Tomoko Ogawa,Noriko Hanamura,Masako Yamashita,Minori Ito,Hiroko Kimura,Takashi Nakamura,Yumi Kashikura,Yuki Nohara,Aya Noro 한국유방암학회 2013 Journal of breast cancer Vol.16 No.2
An abdominal advancement flap (AAF) is a flap that pulls the elevated abdominal skin up and creates the shape of the inferior portion of the breast by making a neo-inframammary fold. Seven patients underwent remodeling using an AAF or a method combining an AAF with other volume displacement techniques after partial mastectomy. The excision volume ranged from 15% to 35%. AAF with only mobilization of the gland flaps was performed in two cases, with lateral mammoplasty in one case, with the round block technique (RBT) in one case, with a modified RBT in one case, and with medial mammoplasty in two cases. Although one patient treated with a RBT had a partial blood-flow insufficiency of the nipple-areola complex, it improved with conservative treatment. The cosmetic results were found to be excellent in three cases, good in three, and fair in one case.
Tomoko Ogawa,Noriko Hanamura,Masako Yamashita,Hiroko Kimura,Minori Ito,Takashi Nakamura,Yumi Kashikura,Yuki Nohara,Aya Noro 한국유방암학회 2012 Journal of breast cancer Vol.15 No.4
We introduce a method combining two oncoplastic techniques for breast-conserving reconstruction. The procedure is as follows: first, an extended glandular flap is made by undermining the breast from both the skin and the pectoralis fascia to the upper edge of the breast at the subclavicular area. After modeling the breast mound with the extended glandular flap, an inframammary adipofascial flap is made. The flap is reflected back to the breast area remodeled using the extended glandular flap. After reshaping the breast, the inframammary line is then re-shaped. This method is indicated for patients with breast cancer in the outer portion of the breast, who have small dense breasts, and have undergone a large excision of about 40% of their breast volume. We treated four patients, all of whom had either excellent or good cosmetic results with no fat necrosis.
Yuki Nohara,Noriko Hanamura,Hisamitsu Zaha,Hiroko Kimura,Yumi Kashikura,Takashi Nakamura,Aya Noro,Nao Imai,Mai Shibusawa,Tomoko Ogawa 한국유방암학회 2015 Journal of breast cancer Vol.18 No.1
Purpose: Although various strategies have been reported, thereare no defined criteria for cosmetic evaluation methods afterbreast-conserving surgery (BCS). Since Asians tend to havesmaller breasts, indistinct inframammary folds, and conspicuousscars, differences in the cosmetic results are expected. So weexamined two subjective methods and one objective method todetermine the differences, and elements necessary for a cosmeticevaluation after BCS. Methods: Frontal photographs of 190Japanese were evaluated using the Harris scale (Harris) and theevaluation method proposed by the Japanese Breast Cancer SocietySawai group (Sawai group) as the subjective methods, andthe Breast Cancer Conservation Treatment cosmetic results(BCCT.core) as the objective method, respectively. In order to examinethe necessary elements for developing a new ideal method,100 out of 190 were selected and assessed separately by sixraters using both the Harris and modified Sawai group methodsin the observer assessment. The correlation between the twomethods was examined using the Spearman rank-correlation coefficient. Results: The results of the BCCT.core and the other twomethods were clearly different. In the observer assessment, theconsensuses of the six raters were evaluated as follows: 27, 27,26, and 20 cases were evaluated as “excellent,” “good,” “fair,”and “poor,” respectively. For the Spearman rank-correlation coefficient,values higher than 0.7 indicated a strong correlation, asseen by the values of 0.909 for the breast shape and 0.345 forthe scar. The breast shape accounted for the most significantpart of the evaluation, and the scar had very little correlation. Conclusion:In this study, we recognized a clear difference betweenthe subjective and objective evaluation methods, and identifiedthe necessary elements for cosmetic evaluation. We would like tocontinue developing an ideal cosmetic evaluation that is similar tosubjective one and is independent from raters.
Antimicrobial Effects of Chlorogenic Acid and Related Compounds
Faisal Kabir,Shigeru Katayama,Noriko Tanji,Soichiro Nakamura 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.3
Chlorogenic acid (CGA) is a natural chemical estercomposed of caffeic acid and (-)-quinic acid, and is furthermetabolized into active compounds in the living body. Here, weaimed to provide fundamental information on the antimicrobialaction of CGA and related compounds against the Gram-negativebacterium Escherichia coli IFO 3301. Bacteriostatic effects wereassessed by spectrophotometry, and bactericidal effects weredetermined by enumerating viable cells on MacConkey agar plates. CGA and related compounds exhibited specific antimicrobialactivity and corresponding reduction in log survival ratio, inwhich ferulic, isoferulic, benzoic, and hydroxybenzoic acidsexhibited obvious antimicrobial activity against E. coli. In a timekillassay, it was observed that bactericidal effects were associatedwith treatment time, temperature, and dose. A reduction in logsurvival ratio was observed at low pH as well as under thermalstress condition. Thus, we demonstrated that CGA and relatedcompounds have not only bacteriostatic effects but alsobactericidal effects.