손상받은고양이 줄무늬체에서 축삭반응에 관한 미세구조적 연구

양남길,조영열,안의태,고정식,박경호,김진국 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

머리에 방사선상해를 입은 흰쥐의 운동조절계에 대한 전자현미경적 연구 - Ⅱ. 방사선조사를 받은 흰쥐 뇌송과체의 미세구조에 대한 연구

조태승,양남길,안의태,고정식 대한해부학회 1991 Anatomy & Cell Biology Vol.24 No.1

알코올이 흰쥐 소뇌피질의 복합당질에 미치는 영향에 관한 조직화학적 연구

조지은,정길남,조운복 부산대학교 과학교육연구소 2006 교사교육연구 Vol.45 No.-

This study was performed to investigate the effects of 10% alcohol on the changes of histological structure and glycoconjugates in rats cerebellar cortex. Sprague-Dawley rats weighing about 200~250 g were divided into control and 10% alcohol treated groups. The treated group with 10% alcohol was divided into 4 subgroups; 1, 2, 4 and 6 weeks alcohol treatment. To investigate the distribution and change of glycoconjugates, nine biotinylated lectins (DBA, SBA, PNA, BSL-1, RCA-1, sWGA, UEA-1, LCA and Con A) were applied according to the avidin-biotin-peroxidase complex methods. The morphological changes in the cerebellar cortex of the 10% alcohol groups were significant compared with the control group. In 10% alcohol groups for 2 and 4 weeks, molecular layer of cerebellar cortex was separated, and number of cells in molecular layer and Purkinje layer decreased. Purkinje cell layer and granular layer were separated. There were extended separation between molecular layer and granular layer matrix, abnormal multiplication and extention of layers. Especially, nerve cells showed histopathological lesions, such as lysis, depression and crush. Because of cerebellar Purkinje cell degeneration, Purkinje cell was fallen apart or got buried in granular layer. In 10% alcohol groups for 6 weeks, size of cerebellar cortex decreased and number and size of cells were also decreased. The change in RCA-1 binding was similar to both drinking and control groups. sWGA binding compared with the control group was decreased 2 and 4 weeks alcohol drinking groups, but showed tendency to increase in 6 weeks group. All lectins binding except sWGA and RCA-1 appeared tendency to increase in drinking groups, especially, LCA binding was notably increased in 6 weeks alcohol drinking group. In conclusion, the present study suggests that alcohol induce significant changes in the morphological structures and glycoconjugates in the rat cerebellar cortex. 흰쥐 소뇌피질의 형태적 구조와 복합당질에 알코올이 미치는 영향을 규명하기 위해 체중 200~250g의 Sprague-Dawley계 흰쥐를 대조군과 알코올음용군으로 나누고 알코올음용군은 10% 알코올을 계속 음용시켜 1주군, 2주군, 4주군, 6주군으로 나누어 연구하였다. 소뇌 피질의 복합당질의 양상을 9종의 biotinylated lectin(DBA, SBA, PNA, RCA-1, sWGA, UEA-1, LCA, Con A, BSL-1)으로 관찰하였다. 알코올음용군에서 소뇌피질의 형태적인 변화를 관찰한 결과 음용기간에 따라 현저한 변화가 나타났다. 알코올음용 1주군에서 대조군과 유의미한 변화가 나타나지 않았으나, 알코올음용 2주 및 4주군의 소뇌피질의 분자층 세포들과 조롱박세포의 수가 크게 줄어들었으며 조롱박층이 과립층과 분리되는 경향이 나타났고 분자층과 과립층 기질이 나누어지며 비정상적인 증식 및 층의 확장 경향이 나타났다. 특히 신경세포들이 용해되거나 신경세포의 모양이 찌그러지고 함몰되는 현상이 나타났으며, 소뇌 조롱박세포의 변성으로 조롱박 세포가 탈락되어지거나, 과립층에 묻혀 구분되지 않는 현상도 나타났다. 알코올음용 6주군에서는 전체적인 소뇌피질의 크기 감소와 더불어 신경세포의 수와 크기가 크게 감소하며 조롱박세포의 함몰, 찌그러짐, 용해현상이 심하게 나타나며 신경세포 이상증식에 의한 다층화가 나타났다. 알코올음용군 흰쥐 소뇌피질의 세포들의 복합당질에 대한 렉틴결합양상은 RCA-1의 경우 대조군에 비해 변화가 없었으나, sWGA는 알코올음용 2주군, 4주군에서 대조군에 비해 감소되었다가 알코올음용 6주군에서 회복되는 경향을 보였다. 그 외 렉틴반응은 증가하는 경향을 나타내었으며 특히 LCA는 알코올음용 6주군에서 많이 증가하였다. 이상의 결과로 보아 알코올섭취는 소뇌피질의 신경세포의 형태적 변화 그리고 복합당질 대사에 심한 영향을 미치는 것으로 사료된다.

상사성을 고려한 배수재 설치 연약점토 지반의 원심모델링

유남재,홍영길,정길수,조한기 강원대학교 산업기술연구소 2007 産業技術硏究 Vol.27 No.A

This paper is results of experimental research on the effect of application of similarity related to permeability of soil on the consolidation behavior as centrifuge modeling of consolidation is performed with the centrifuge model facility. In this research, the permeability of soil was controlled by changing the viscosity of porewater as the mixed water with glycerin was used during the centrifuge model experiments. The effect of drainage path on consolidation was investigated by installing the vertical drains. A serise of centrifuge model tests with conditions of single vertical and radial horizontal drainage were carried out. Kaolinite and Jumunjin standard sand were used as soft clay and surcharges respectively during tests. For testing condition of single vertical drainage considering similarity of permeability, it was found that consolidation with mixed porewater with glycerin was delayed in comparisons with test results with water only. For conditions of horizontal drainage with vertical drains, a low permeability by changing the viscosity of pore water resulted in delayed degree of consolidation at an initial stage of consolidation. But, it predicted not much differences in settlement as long as the consolidation time was sufficiently long enough to finish consolidation. Consequently, it was found that similarity in permeability should be considered to be critical for the case of centrifuge model experiments related to consolidation with long drainage path.

심근부종으로 표현된 과호산구증에 동반된 호산구성 심근염 1예

심미승,안영미,조홍근,신길자,정남식,조상호 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

Automating Quality system - New Rules for Pattern Identification in Control Charts

( Nam Gil Cho ) 고려대학교 공학기술연구소 1996 생산기술연구소보 Vol.3 No.-

Validity of the Transverse Abdominis Thickness Change for Abdominal Draw-in Maneuver Using Biofeedback Sensor

Nam-Goo Kang(Nam-Goo Kang),Jong-Gil Seo(Jong-Gil Seo),Won-Nyeong Cho(Won-Nyeong Cho),Jin-Wook Sung(Jin-Wook Sung) 한국임상움직임치료학회 2022 한국임상움직임치료학회지 Vol.2 No.2

Background Transverse abdominis (TrA) is an important local muscle that plays an essential role in the core. Ultrasound imaging is a reliable and valid technique for analyzing TrA muscle thickness. However, this method requires skilled operators. Biofeedback devices have achieved similar clinical outcomes to ultrasound. Even so, few studies have examined the validity of this biofeedback. Objectives This study aimed to assess whether changes in waist circumference, as determined by changes in the thickness of TrA detected with a stretch sensor made with a biofeedback device, produce results similar to those obtained through ultrasound. Methods Nineteen healthy participants were recruited for this study. Ultrasound measurement of the thickness of TrA was compared with the simultaneous measurement of the stretch sensor biofeedback device. Results Acceptable validity was found between the thickness of the TrA and the stretch sensor displayed on-screen waist circumference (Pearson correlation = -0.69, p = 0.03). Conclusions The study confirmed that changes in the grape bar on the screen of the stretch sensor application could be employed as a suitable indicator for assessing the changes to the thickness of the TrA muscle.

호산구증가증과 PDGFRB 유전자 재배열을 보인 골수 종양 1예

조남길 ( Nam Gil Cho ),김대진 ( Daejin Kim ),심민정 ( Minjung Shim ),정소영 ( So Young Chong ) 대한내과학회 2017 대한내과학회지 Vol.92 No.1

Myeloid neoplasia with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) rearrangements is an uncommon Philadelphia-negative myeloproliferative neoplasm. Their most common morphological diagnosis is chronic myelomonocytic leukemia with eosinophilia, which is associated with t(5;12)(q33;p13) and results in the formation of the ETV6-PDGFRB fusion gene. Here, we report a 49-year-old man with a myeloid neoplasm with a PDGFRB rearrangement, who was incidentally diagnosed with hyperleukocytosis and eosinophilia during a health screening. A chromosome analysis of a bone marrow sample revealed 46, XY, t(5;12)(q33;p13), and fluorescence in situ hybridization analysis revealed the PDGFRB gene rearrangement. The patient was treated with imatinib and subsequently achieved complete hematological and molecular remission. (Korean J Med 2017;92:79-83)

Degradation in Steels: Transformation Plasticity

Cho, Yi-Gil,Han, Heung-Nam The Korean Ceramic Society 2012 한국세라믹학회지 Vol.49 No.1

Super-plastic deformation that originates from transformation plasticity has favorable aspects for steels with improved strength and ductility. However, it also causes undesirable deformation of products or specimens, leading to their degradation. This article reviews recent investigations of transformation plasticity. A combination of newly suggested models, numerical analyses, and novel experiments has attempted to reveal the mechanism. Since the nature of the transformation plasticity is still unclear, there are significant challenges still to be solved. Fundamental understanding of transformation plasticity will be essential for the development of advanced steels.

Effect of Low Frequency Cerebellar Repetitive Transcranial Magnetic Stimulation on Balance Impairment in Patients With Cerebral Infarction

Nam-Gyu Im,Kyung-Rok Oh,Min-gil Kim,Young Lee,Na-Na Lim,Tae-Hwan Cho,Su-Ra Ryu,Seo-Ra Yoon 대한재활의학회 2022 Annals of Rehabilitation Medicine Vol.46 No.6

Objective To investigate the effect of low frequency cerebellar repetitive transcranial magnetic stimulation (rTMS) on balance impairment in patients with cerebral infarction.Methods Thirty-two patients were randomly divided into two groups: rTMS group (n=16) and control (n=16). In the rTMS group, treatment was performed five times per week for 2 weeks (10 sessions), and in the control group, a sham coil was used with the sound and sensation of scalp similar to the rTMS coil. Patients in both groups underwent a conventional rehabilitation program. Berg Balance Scale (BBS) was used as the primary outcome measurement. Timed Up and Go test (TUG), 10-m walk test (10mWT), and Activity-specific Balance Confidence scale (ABC) were used as the secondary outcome measurement. All scales were measured at baseline (T0), after 10 sessions of rTMS (T1), and at 4 weeks after treatment completion (T2) by therapists with over 5 years of clinical experience.Results There were significant improvements between T0 and T1, and between T0 and T2, for all assessed items in the rTMS group. Whereas there were significant improvements between T0 and T1, and between T0 and T2, for the BBS and 10mWT in the control group. TUG (-4.87±5.05 vs. -0.50±2.97 seconds) and ABC score (8.10±8.33 vs. 0.16±0.97) were observed significant differences in comparison of the changes from T0 to T1 between the two group. BBS score (4.40±3.66 vs. 1.88±3.14), TUG (-4.87±4.56 vs. -0.62±2.96 seconds) and ABC score (8.22±7.70 vs. -0.09±0.86) differed significantly from T0 to T2 between the two groups.Conclusion Our findings suggest that low-frequency cerebellar rTMS is helpful for improving balance in patients with cerebral infarction, and maybe a beneficial treatment for these patients.