New Evidence of Alleles (V199I and G52S) at the PRKAG3 (RN) Locus Affecting Pork Meat Quality

Chen, J.F.,Dai, L.H.,Peng, J.,Li, J.L.,Zheng, R.,Zuo, B.,Li, F.E.,Liu, M.,Yue, K.,Lei, M.G.,Xiong, Y.Z.,Deng, C.Y.,Jiang, S.W. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.4

The porcine PRKAG3 (RN) gene encodes the regulatory gamma subunit of adenosine monophosphate-activated protein kinase (AMPK), which is a good candidate gene affecting meat quality. In this study, the effects of two missense mutations A595G (Ile199Val) and G154A (Gly52Ser) in porcine PRKAG3 gene on meat quality traits were studied in M. Longissimus dorsi (LD), M. Semispinalis capitis (SC) and M. Biceps femoris (BF) from different populations of 326 pigs. The PRKAG3 alleles 199I, 199IV, 52S and 52G were identified with PCR-RFLPs and all genotypes - 199I/199I, 199I/199V, 199V/199V, 52S/52S, 52S/52G and 52G/52G - were found. The frequency of V allele was larger than that of I allele in all populations. I allele frequency was zero in Chinese Meishan pigs (population D) especially. G allele frequency was larger than that of S allele in all populations except Large White (population A). Both variations at the PRKAG3 locus significantly affected these meat quality traits. The pork meat quality has not previously been established in Meishan or crosses thereof. The results suggested that generally pH of LD, SC and BF was higher in Meishan pigs than that in other populations. Moreover, Meishan pigs showed higher water-holding capacity and intramuscular fat (IMF), lower water content and water loss percentage compared to other populations in terms of the two variations. The results present here supply new evidence that alleles V199I and G52S at the PRKAG3 locus affect pork meat quality and provide useful information on pork production.

Bleomycin에 의한 여성 요도암 및 남성 음경암 치험 5례 : 5 Cases Report

유태형,이무상,이진무,왕종순 최신의학사 1978 最新醫學 Vol.21 No.1

Primary carcinoma of the penis is a relatively common disease, but carcinoma of the female urethra is a rare disease comprising 0. 016% of all gynecologic neoplasms. Bleomycin, a new antitumor antibiotic elaborated by Streptomyces verticillus, have shown the efficacy against squamous cell carcinoma, and other malignancies. Recently, we have experienced 3 cases of the female urethal carcinoma and 2 cases of the male penile carcinoma. Herein, we presented the above cases treated with Bleomycin and radiation, and then reviewed the literatures.

H₂O₂/HCl 처리한 Ti 임플란트의 생체활성 평가

유재선,권오성,이오연,이민호,송기홍,Yue J. S.,Kwon O. S.,Lee O. Y.,Lee M. H.,Song K. H. 한국재료학회 2005 한국재료학회지 Vol.15 No.5

Surface treatment play an important role in nucleating calcium phosphate deposition on surgical Ti implant. Therefore, the purpose of this study is to examine whether the precipitation of apatite on cp-Ti and Ti alloys are affected by surface modification in HCl and $H_2O_2$ solution. Specimens were then chemically treated with a solution containing 0.1 M HCl and 8.8M $H_2O_2$ at $80^{\circ}C$ for 30 mins, and subsequently heat-treated at $400^{\circ}C$ for 1 hour. All specimens were immersed in the HBSS with pH 7.4 at $36.5^{\circ}C$ for 15 days, and the surface was examined with XRD, SEM, EDX ana XPS. Also, pure Ti, Ti-6Al-4V and Ti-6Al-7Nb alloy specimens with and without surface treatment were implanted in the abdominal connective tissue of mice for 4 weeks. All specimens chemically treated with HCl and $H_2O_2$ solution have the ability to form a apatite layer in the HBSS which has inorganic ion composition similar to human blood plasma. The average thickness of the fibrous capsule surrounding the specimens implanted in the connective tissue was $38.57\;{\mu}m,\;62.27\;{\mu}m\;and\;45.64\;{\mu}m$ in the cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloy specimens with the chemical treatment respectively, and $52.20\;{\mu}m,\;75.62\;{\mu}m\;and\;66.56\;{\mu}m$ in the commercial specimens of cp-Ti, Ti-6Al-4V and Ti-6Al-7Nb without any treatment respectively. The results of this evaluation indicate that the chemically treated cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloys have better bioactivity and biocompatibility compared to the other metals tested.

Mechanical Properties of Spark Plasma Sintering Nd-Fe-B Permanent Magnets

M. Yue,A. Cao,W. Liu,J. Zhang 한국자기학회 2007 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Synthesis of TiO₂ Nanotubes and Their Sensitivity for Toluene Gas

Yue, H.Y.,Huang, S.,Guo, E.J.,Wang, L.P.,Kang, F.W.,Yu, Z.M.,Guo, Y.K.,Sun, F.L. The Korean Powder Metallurgy Institute 2011 한국분말재료학회지 (KPMI) Vol.18 No.1

$TiO_2$ nanopowders with anatase structure were firstly prepared by controlling the pH value of a precursor solution without any heat-treatment at room temperature. The prepared $TiO_2$ nanopowders were hydrothermally treated in 10M NaOH solution at $170^{\circ}C$. Then, the samples were washed in DI water or 0.1M HCl. The $TiO_2$ nanotubes were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM). The gas sensitivity of $TiO_2$ nanotubes for toluene gas was also investigated. The results show that $TiO_2$ nanotubes can be prepared by hydrothermal treatment. The morphology of $TiO_2$ nanotubes prepared by 0.1M HCl washing is destroyed to some extent. $TiO_2$ nanotubes with DI water washing show better sensitivity than that with 0.1M HCl washing.

Electrical Resistivity and Demagnetization Characteristics of Salt-added Nd-Fe-B-type Magnet

M. S. Kang,K. M. Kim,H. W. Kwon,D. Wu,M. Yue,M. C. Kang,C. W. Yang,D. H. Kim,J. G. Lee,J. H. Yu 한국자기학회 2019 Journal of Magnetics Vol.24 No.3

Nd-Fe-B-type die-upset magnet with high electrical resistivity was fabricated by hot-deforming the mixture of melt-spun Nd-Fe-B-type flakes (MQU-F: Nd13.6Fe73.6Co6.6Ga0.6B5.6) and Dy-containing salts: eutectic (DyF₃–LiF) salt mixture and DyF₃ single salt. Profound electrical resistivity enhancement was feasible in the Nd-Fe-B-type die-upset magnet by adding Dy-containing salts. More profound electrical resistivity enhancement was achieved in the magnet added with dielectric eutectic (DyF₃–LiF) salt mixture with respect to the magnet added with single DyF₃ salt. This was attributed to better electrical insulation between the flakes by forming more continuous coverage of the flake interface with the easily melted dielectric salt. Coercivity of the die-upset magnet was also profoundly enhanced by optimal addition of Dy-containing salts, and this was attributed to substitution of some Nd in the Nd₂Fe14B-type grains near flake surface by Dy atoms from the added salt. Kerr microscopy revealed that for both the magnets with or without salt addition, formation of reverse domain initiated mostly inside the flake. Reversed domain started to form at higher reverse field for the magnet added with Dy-containing salt than for the magnet without salt addition. Practical demagnetization occurred largely by formation of new reverse domains at random places rather than enlargement of previously formed reverse domain for both the magnets with or without salt addition.

High Performance Nd-Fe-B-type Permanent Magnet with High Electrical Resistivity

H. W. Kwon,K. M. Kim,M. S. Kang,D. Wu,M. Yue,J. G. Lee,J. H. Yu 한국자기학회 2017 한국자기학회 학술연구발표회 논문개요집 Vol.2017 No.11

An Approach to Transit Path Design Using GIS

S.V.C. Sekhar, Wen Long Yue, M.A.P.Taylor 서울시립대학교 도시과학연구원 2004 International journal of urban sciences (IJUS) Vol. No.

The design of public transportation networks is complex and can include conflicting objectives. Networks designed to minimise travel time may not fulfil the requirement of maximum coverage and accessibility. In this context, a multi-criteria approach for transit alignment design has been developed to maximise a range of objectives using census data. Whenever a subdivision is developed in a suburban region of a medium sized city, transit operators often receive requests to link the city centre with the new locality via new routes. Traditionally, implementation of routing a new bus service is based on a ‘common sense’approach. This can lead to the development of an irrational network of public transport routes. This research offers an alternative approach, which essentially optimises ulticriteria for planning transit routes. This research has proved that it is worth considering such options for connecting origin-destination zones with a new bus service.

Bone Morphogenic Protein Is a Viable Adjunct for Fusion in Minimally Invasive Transforaminal Lumbar Interbody Fusion

M Mashfiqul Arafin Siddiqui,Ana Rosario P. Sta.Ana,William Yeo,Wai-Mun Yue 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.6

Study Design: Comparison of prospectively collected data of patients undergoing minimally invasive surgery transforaminal lumbar interbody fusion (MIS-TLIF) with and without recombinant human bone morphogenic protein 2 (BMP). Purpose: To compare the clinical, radiological outcome and complications of patients undergoing MIS-TLIF with and without BMP. Overview of Literature: BMP is an effective fusion enhancer with potential complications. Direct comparison of MIS-TLIF with and without BMP is limited to retrospective studies with short follow-up. Methods: From June 2005 to February 2011, consecutive cases of MIS-TLIF performed by a single surgeon were included. North American Spine Society (NASS) score, Oswestry disability index (ODI), Short Form-36 (SF-36), and visual analogue score (VAS) were assessed preoperatively and at 6 and 24 months postoperatively. Fusion rates and complications were noted. Results: The 252 cases comprised 104 non-BMP and 148 BMP cases. The BMP group was significantly older (mean age, 60.2 vs. 53.9; p <0.01). Preoperative scores were similar. Immediate postoperative morphine usage was significantly lower in the BMP group (12.4 mg vs. 20.1 mg, p <0.01). At 6 months, the BMP group had lower VAS back and leg pain scores (p <0.01). At 2 years, the BMP group had better leg pain scores (p <0.01), ODI (15.4 vs. 20.3, p =0.04) and NASS scores (8.8 vs. 15.8, p <0.01). Both groups showed significant clinical improvement compared to their preoperative levels. The BMP group attained a significantly higher rate of fusion at 6 months follow-up (88.4% vs. 76.8%, p =0.016) with no difference at 2 years. The non-BMP and BMP group had 12 (11.5%) and 9 (6.1%) complications and 5 (4.8%) and 2 (1.4%) reoperations, respectively. Conclusions: The use of BMP to augment fusion in MIS-TLIF is an acceptable alternative that has potential benefits of less pain in early and intermediate postoperative follow-up.

Dislocation-oxide interaction in Y₂O₃ embedded Fe: A molecular dynamics simulation study

Azeem, M. Mustafa,Wang, Qingyu,Li, Zhongyu,Zhang, Yue Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.2

Oxide dispersed strengthened (ODS) steel is an important candidate for Gen-IV reactors. Oxide embedded in Fe can help to trap irradiation defects and enhances the strength of steel. It was observed in this study that the size of oxide has a profound impact on the depinning mechanism. For smaller sizes, the oxide acts as a void; thus, letting the dislocation bypass without any shear. On the other hand, oxides larger than 2 nm generate new dislocation segments around themselves. The depinning is similar to that of Orowan mechanism and the strengthening effect is likely to be greater for larger oxides. It was found that higher shear deformation rates produce more fine-tuned stress-strain curve. Both molecular dynamics (MD) simulations and BKS (Bacon-Knocks-Scattergood) model display similar characteristics whereby establishing an inverse relation between the depinning stress and the obstacle distance. It was found that (110)_oxide || (111)_Fe (oriented oxide) also had similar characteristics as that of (100)_oxide || (111)_Fe but resulted in an increased depinning stress thereby providing greater resistance to dislocation bypass. Our simulation results concluded that critical depinning stress depends significantly on the size and orientation of the oxide.