http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Seon Bok Lee ),( Hye Won Hwang ),( Ji Hye Heo ),( Hee Seong Yoon ),( Yun-kyoung Cho ),( Eunkyung Chung ),( Myung-shin Jeon ),( Si Hyub Lee ),( Hyun-tae Shin ),( Ji Won Byun ),( Jeonghyun Shin ),( Su 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Atopic dermatitis(AD) is a chronic and relapsing inflammatory skin disease that is treated with immunosuppressants. However, long-term use of immunosuppressants may cause toxicity and severe side effects. Objectives: This study aimed to confirm the long-term efficacy and safety of clonal mesenchymal stem cell therapy in adult patients with moderate to severe AD that was refractory to conventional treatments. Methods: A single-center, open-labeled investigator-initiated clinical trial for the therapeutic use of allogeneic bone marrow-derived clonal MSCs in five adults with moderate to severe AD was conducted intravenously. Eczema Area and Severity Index (EASI), Severity Scoring for AD and Investigator Global Assessment scale were used to evaluate the effectiveness of the therapy. Results: The clinical response assessment values such as EASI improved significantly at 16 weeks, and 80% (4/5) of the patients achieved EASI-50 after one or two treatment cycles. Patients were observed for long-term efficacy and safety for an average of 38 weeks and showed no serious side effects. Among the cytokines tested, CCL-17, IL-13 and IL-22 significantly decreased at the endpoint of the five participants, two patients who maintained good clinical response over 84 weeks showed increased IL-17 cytokine levels in the blood. Conclusion: This study suggests that clonal mesenchymal stem cell therapy could be safe and effective treatment option for chronic refractory AD.
신선미(Seon-Mee Shin):마경희(Kyoung-hee Ma),유정미(Jeongmi Yoo) 한국여성정책연구원 2016 한국여성정책연구원 연구보고서 Vol.2016 No.-
1. 연구개요 가. 연구목적 미래여성인재 육성정책은 관리직과 전문직에 여성진출을 확대함으로써 사회 전반에 걸쳐 여성의 경제활동 참여와 성평등 사회 실현을 선도하려는 목적을 가지고 있다. 이 정책은 어려운 여건 속에서 나름대로 성과를 거두고 있으나 관련 사업들 간에 연관성 부족을 비롯하여 여러가지 문제점이 발견되고 있다. 이에 관련 사업들이 하나의 시스템을 구성하여 상호 연관성을 높여나갈 수 있도록 개선방안을 제안하고자 한다. 나. 연구내용 □ 미래여성인재 육성정책의 범위와 배경에 관한 정책자료 및 선행연구 결과, 그리고 정책개발에 필요한 학문적 기초 점검(2장) □ 미래여성인재 육성정책을 구성하는 세 가지 하위 정책 1)여성인재의 발굴 및 DB 구축, 2)여성인재아카데미사업, 3)여성인재 DB 활용정책의 내용과 추진실적 검토(3장) □ 미래여성인재 육성정책의 개선방안 도출 : 1)정책 목적, 범위, 환류시스템 보완, 3)여성인재 발굴 및 활용정책 개선방안, 4)여성인재아카데미사업 개선방안(4장) 다. 연구방법 □ 문헌분석 : 미래여성인재 육성정책에 관한 정부부처의 문서자료, 보도자료, 신문기사, 관련 법령 등 □ 개인 및 초점집단 면접조사 : 개인별 면접조사 6명, 초점집단(3개 집단) 면접조사 16명 라. 연구기간 : 2016. 9. 1. - 2016. 11. 30. 2. 미래여성인재 육성정책의 추진현황 가. 여성인재의 발굴 및 DB 구축 □ 정책목표 : 2017년까지 10만 명의 여성인재 발굴?DB화 □ 여성인재 DB 등록자의 특징 : 1)31개 전문분야 중에서 문화/예술/체육/관광 분야(9,348명, 10.9%)가 가장 많고 소방/방재/기상분야(154명, 0.2%)가 가장 적음. 2)직종별로는 교수, 연구원 등 교육인(34,614명, 40.2%), 경제/기업인(19,945명, 23.2%), 공무원(13,057명, 15.2%)이 가장 많음(표 Ⅲ-4)). □ 문제점 : 인력과 물리적 시스템의 한계로 등록된 정보의 사실 여부를 검증하고 정보를 지속적으로 업데이트하는 체계적인 절차 부재 나. 여성인재아카데미사업 □ 정책목표 : 2013년 하반기부터 2017년까지 총 3만명 교육수료 □ 주요대상 : 여성 중간관리자, 여성 고위관리자, 전문직 여성, 기타 여성리더(지역여성리더, NGO 여성 리더 등) □ 성과 : 1)교육인프라 구축 및 다수의 교육 인원, 2)교육참여자의 높은 교육 만족도, 3)역량진단 도구 및 강의안의 자체개발, 4)대상별 특성화된 교육 프로그램 체계화 시도 □ 문제점 : 1) 전략적 교육운영의 부족, 2) 여성인재 발굴 및 활용 정책과의 연계 부족, 3) 공공기관/민간기업 대상 교육의 타당성, 지속성 문제, 4)기관별 경영진 및 인사담당자 대상의 여성인재육성 관련 교육 부재 다. 여성인재 DB 활용 정책 □ 정책목표 : 2017년까지 4급 이상 여성공무원 비율 15%, 정부위원회 위촉직 여성비율 40%, 여성 교장?교감 비율 37.3%, 공공기관의 여성 관리자 비율 18.8%(표 Ⅱ-1). □ 추진실적 -정부위원회 위촉직 여성비율 : 중앙행정기관 34.5%, 지방자치단체 30.1%(표 Ⅲ-22, 표 Ⅲ-23) -2013년부터 2016년 10월말까지 총 333개 정부위원회에 3,689명의 여성인재추천(본문 p.32) □ 문제점 : 여성인재 DB 구축 목적은 “여성인재의 육성 및 사회참여 확대 지원”에 있으나 실제 활용처는 공직후보자 추천(정부위원회 위원, 개방형 및 공모직위, 책임운영기관장, 공공기관 임원 등) 등 인사 상 목적으로만 활용되고 있음. This paper is designed to check the status of future female talent cultivation policies and to present ways to improve such policies. Future female talent cultivation policies aim to increase the number of female managers and professionals especially in the public sector. Key research contents include 1) the scope and background of future female talent cultivation policies; 2) the status of three exemplary policies; and 3) ways to enhance policies. Literature reviews and focus group (22 persons) interviews were used for this research study. The policies have been carried out mainly in the public sector but need to expand to include the private sector in the future. More than 86,000 talented women (middle managers and higher-ranking administrators/professionals) are registered in the Female Talent DB. Data on 100,000 female talents are expected to be gathered by 2017. In order to raise the percentage of female managers in the public sector, the following three policy goals should be achieved by 2017: 1) increasing the proportion of female managers in public institutions to 18.8%; 2) improving the percentage of female principals and vice principals to 37.3%; and 3) raising the share of women appointed in government committees to 40.0%. Against this backdrop, policy improvement plans include 1) expanding the scope of female talent data used; 2) strategically gathering information via the analysis of the Female Talent DB; 3) enhancing the Female Talent DB operation system; 4) recommending sectors where curricula for the Women Leader Academy should preferentially expand; and 5) a module for curricula for the Academy for Women in construction.
Study on dynamic behavior analysis of towed line array sensor
Shin, Hyun-Kyoung,Ryue, Jung-Soo,Ahn, Hyung-Taek,Seo, Hee-Seon,Kwon, Oh-Cho The Society of Naval Architects of Korea 2012 International Journal of Naval Architecture and Oc Vol.4 No.1
A set of equations of motion is derived for vibratory motions of an underwater cable connected to a moving vehicle at one end and with drogues at the other end. From the static analysis, cable configurations are obtained for different vehicle speeds and towing pretensions are determined by fluid resistance of drogues. Also the dynamic analysis is required to predict its vibratory motion. Nonlinear fluid drag forces greatly influence the dynamic tension. In this study, a numerical analysis program was developed to find out the characteristic of cable behaviour. The motion is described in terms of space and time coordinates based on Chebyshev polynomial expansions. For the spatial integration the collocation method is employed and the Newmark method is applied for the time integration. Dynamic tensions, displacements, velocities, accelerations were predicted in the time domain while natural frequencies and transfer functions were obtained in the frequency domain.
How could you management in the class III obese patient to do Gynecologic Laparoscopic surgery?
( Seon Mi Lee ),( Hyun Kyoung Seo ),( Jae Yoon Jo ),( Hee Jung Lee ),( Yeon Jee Lee ),( In Ae Cho ),( Jeong Kyu Shin ),( Won Jun Choi ),( Jong Hak Lee ),( Won Young Paik ),( Soon Ae Lee ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
All over the world, obese people was twice since 1980. In 2014, over 1.9 billion adults were overweight, including over 600 million obese people. Obesity is worldwidely critical problem, and the people have high risk of morbid conditions such as hypertension, diabetes mellitus, hypercholesterolemia, obstructive sleep apnea, and malignancies including endometrial cancer and breast cancer. If obese patients is operated, the surgeons have to prepare more carefully in operation. Also, post operation complications including surgical site infection, venous thrombus and wound complications are more prevalent in them than normal-weight patient. The same applies to Gynecologic surgery. We reported the case of laparoscopic surgery in class III obese woman (class I obesity is defined as a BMI of 30 to less than 35; class II obesity is defined as a BMI of 35 to less than 40; and class III obesity is defined as a BMI of 40 or greater, is considered morbid obesity) because Endometrial hyperplasia without atypia was diagnosed by dilatation and curettage of uterus. In the preoperative stage, basically, we performed chest x-ray, an electrocardiogram, echocardiography and laboratory evaluation were also performed. In the intraoperative stage, She was posted the HELP (head elevated laryngoscopy position) using blankets under back, shoulders and the head and neck to provide sufficient lift for airway visualization. She underwent laparoscopic hysterectomy with bilateral salpingo-oophorectomy, the surgery finished well. Although, The patient was discharged without any complication at 4 days after surgery, She re-entered hospital due to operation wound problem. After additional treatment such as dressing, antibiotics medications, the wound healing is finished. The more obese patients, the more doctors face same problems as above. Therefore, Gynecologic surgeons should have the knowledge of care and guidelines for preoperative, intraoperative and postoperative management.
Jiwon Shin,Ok Hee Woo,Hye Seon Shin,Sung Eun Song,Kyu Ran Cho,Bo Kyoung Seo 대한영상의학회 2022 대한영상의학회지 Vol.83 No.5
Purpose To evaluate the diagnostic performance of digital breast tomosynthesis (DBT) with the two-dimensional synthesized mammogram (2DSM), compared to full-field digital mammography (FFDM), for suspicious microcalcifications in the breast ahead of stereotactic biopsy and to assess the diagnostic image visibility of the images. Materials and Methods This retrospective study involved 189 patients with microcalcifications, which were histopathologically verified by stereotactic breast biopsy, who underwent DBT with 2DSM and FFDM between January 8, 2015, and January 20, 2020. Two radiologists assessed all cases of microcalcifications based on Breast Imaging Reporting and Data System (BI-RADS) independently. They were blinded to the histopathologic outcome and additionally evaluated lesion visibility using a fivepoint scoring scale. Results Overall, the inter-observer agreement was excellent (0.9559). Under the setting of category 4A as negative due to the low possibility of malignancy and to avoid the dilution of malignancy criteria in our study, McNemar tests confirmed no significant difference between the performances of the two modalities in detecting microcalcifications with a high potential for malignancy (4B, 4C, or 5; p = 0.1573); however, the tests showed a significant difference between their performances in detecting microcalcifications with a high potential for benignancy (4A; p = 0.0009). DBT with 2DSM demonstrated superior visibility and diagnostic performance than FFDM in dense breasts. Conclusion DBT with 2DSM is superior to FFDM in terms of total diagnostic accuracy and lesion visibility for benign microcalcifications in dense breasts. This study suggests a promising role for DBT with 2DSM as an accommodating tool for stereotactic biopsy in female with dense breasts and suspicious breast microcalcifications.