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용액 공정 기반의 인듐 아연 산화물 트랜지스터의 PMMA 보호막 여부에 따른 신뢰성 평가
허관준 ( Kwan Jun Heo ),엄주송 ( Ju Song Eom ),조현아 ( Hyeonah Jo ),최성곤 ( Seong Gon Choi ),정병준 ( Byung Jun Jung ),김성진 ( Sung Jin Kim ) 대한금속재료학회(구 대한금속학회) 2016 대한금속·재료학회지 Vol.54 No.4
We investigated poly(methyl methacrylate) (PMMA) passivation of solution-processed indium zinc oxide (IZO) thin-film transistors (TFTs). PMMA provides solution-processability and good barrier characteristics against environmental elements such as water and oxygen. The PMMA passivation layers protect the IZO active layer of the TFTs without deteriorating their performance during gate bias stress measurements under ambient conditions, and improve their electrical properties by decreasing leakage current. Moreover, the potential to safely manipulate IZO-TFTs after PMMA passivation was proven by realizing a simple n-channel resistive-load inverter.
급속열처리 기술을 이용한 rutile 구조를 가지는 TiO2-X/TiO2 기반의 저전압 저항 스위칭 메모리에 관한 연구
허관준 ( Kwan Jun Heo ),엄주송 ( Ju Song Eom ),김성진 ( Sung Jin Kim ) 대한금속재료학회(구 대한금속학회) 2015 대한금속·재료학회지 Vol.53 No.9
The resistive switching properties driven by low voltage in a nano-scale resistiverandom- access-memory device composed of Al(top)/TiO2-X/TiO2/Al(bottom) were investigated in this paper. TiO2-X and TiO2 layers were deposited by the atomic layer deposition method and a TiO2-X layer was added during the process of rapid-thermal-annealing at 600 °C to induce oxygen vacancies. Structural analyses by using X-ray diffraction suggested that the TiO2-X film annealed at this temperature changes from an amorphous to a rutile phase. The oxygen vacancies of the TiO2-X region acted as traps for electrons and led to memory behavior. The device exhibited resistive-random-access-memory behavior consistent with resistive switching properties such as a high current on/off ratio greater than 1000:1, low-voltage driving less of han 0.5 V, and nonvolatility for over 1.0 × 105s.
Jun, Kyung Ran,Choi, Sung-Eun,Cha, Choong-Hwan,Oh, Heung-Bum,Heo, Yong-Seok,Ahn, Hong-Yup,Lee, Kwan-Jeh KOREAN ACADEMY OF MEDICAL SCIENCE 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22 No.6
<P>The aims of this study were to summarize results on the association of HLA-DRB1 with rheumatoid arthritis (RA) in Asians and to determine if the shared epitope (SE) hypothesis could explain the meta-analysis results. Among the papers published between January 1987 and July 2006 on RA susceptibility in Asian-Mongoloid populations (Korean, Japanese, Chinese, and Thai), 12 were selected for the meta-analysis. Mongoloid-Asian patients with RA had significantly higher frequencies of HLA-DRB1*0101, *0401, *0410, and *1001 than controls (OR 1.5-2.1, <I>p</I><0.05 for association). When analyses were restricted to more ethnically homogeneous populations, HLA-DRB1*0405 showed a significant susceptibility to RA in Koreans (OR 5.65, 95% CI 4.32-7.39), whereas the HLA-DRB1*0301, *0403, *0406, *0701, *1301, and *1405 alleles showed protective association with RA (OR 0.32-0.70, <I>p</I><0.05 for association). In conclusion, it was found that HLA-DRB1 *0101, *0401, *0405, *0410, and *1001 are susceptible, while HLA-DRB1*0301, *0403, *0406, *0701, *1301, and *1405 are protective in Asian-Mongoloids. All the RA-associated alleles except DRB1*0301 could be explained by the structural model supporting the SE hypothesis that RA susceptibility is determined by the combination of amino acid residues at HLA-DR β71 and β74, not by β71 alone.</P>
Jeong Heo,Yoon Jun Kim,Sung Wook Lee,Youn-Jae Lee,Ki Tae Yoon,Kwan Soo Byun,Yong Jin Jung,Won Young Tak,Sook-Hyang Jeong,Kyung Min Kwon,Vithika Suri,Peiwen Wu,Byoung Kuk Jang,Byung Seok Lee,Ju-Yeon Ch 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.4
Background/Aims: Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of hepatic impairment, comorbidities, or prior treatment failure. We investigated the efficacy and safety of sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir for 12 weeks in HCV-infected Korean adults. Methods: This Phase 3b, multicenter, open-label study included 2 cohorts. In Cohort 1, participants with HCV genotype 1 or 2 and who were treatment-naive or treatment-experienced with interferon-based treatments, received sofosbuvir–velpatasvir 400/100 mg/day. In Cohort 2, HCV genotype 1 infected individuals who previously received an NS5A inhibitor-containing regimen ≥ 4 weeks received sofosbuvir–velpatasvir–voxilaprevir 400/100/100 mg/day. Decompensated cirrhosis was an exclusion criterion. The primary endpoint was SVR12, defined as HCV RNA < 15 IU/mL 12 weeks following treatment. Results: Of 53 participants receiving sofosbuvir–velpatasvir, 52 (98.1%) achieved SVR12. The single participant who did not achieve SVR12 experienced an asymptomatic Grade 3 ASL/ALT elevation on day 15 and discontinued treatment. The event resolved without intervention. All 33 participants (100%) treated with sofosbuvir–velpatasvir–voxilaprevir achieved SVR 12. Overall, sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir were safe and well tolerated. Three participants (5.6%) in Cohort 1 and 1 participant (3.0%) in Cohort 2 had serious adverse events, but none were considered treatment-related. No deaths or grade 4 laboratory abnormalities were reported. Conclusions: Treatment with sofosbuvir–velpatasvir or sofosbuvir–velpatasvir–voxilaprevir was safe and resulted in high SVR12 rates in Korean HCV patients.
Preparation of Mesoporous Materials and Thin Films It`s Application for DNA Sensor
( Seung Jun Han ),( Soon Young Heo ),( Keun Ho Park ),( Soo Lee ),( Byung Kwan Kim ),( Jin Heung Kim ) 한국유화학회 2004 한국응용과학기술학회지 Vol.21 No.4
N/A Highly ordered pure-silica MCM-41 materials possessing well-defined morphology have been successfully prepared with surfactant used as a template. The fabrication of mesoporous silica has received considerable attention due to the need to develop more efficient materials` for catalysis, separations, and chemical sensing. The surface modified MCM-41 was used as anadsorbent for biomolecules. Silica-supported organic groups and DNA adsorption on surface modified MCM-41 were investigated by FT-IR and UV-Vis spectrometer, respectively. The use of MCM-41 as the modification of electrode surfaces were investigated electrochemical properties of metal mediators with biomolecules. The modified ITO electrodes increased peak currents for a redox process of [Ru(bpy)₃]^(2+) relative to the bare electrode. The electrochemical detection of DNA by cyclic voltammetry when the current is saturated in the presence of the mediator appeared more sensitive due to a higher catalytic current on the MCM-41 supported electrodes modified by carboxylic acid functional groups. The carboxyl or amine groups on the surface of MCM-41 interact and react with the -NH2 groups of guanine and backbone, respectively. Highly ordered mesoporous materials with organic groups could find applications as DNA sensors.
Preparation of Mesoporous Materials and Thin Films It's Application for DNA Sensor
Seung-Jun Han,Soon-Young Heo,Keun-Ho Park,Soo Lee,Byung-Kwan Kim,Jin-Heung Kim 한국유화학회 2004 한국응용과학기술학회지 Vol.21 No.4
Highly ordered pure-silica MCM-41 materials possessing well-defined morphology have been successfully prepared with surfactant used as a template. The fabrication of mesoporous silica has received considerable attention due to the need to develop more efficient materials' for catalysis, separations, and chemical sensing. The surface modified MCM-41 was used as anadsorbent for biomolecules. Silica-supported organic groups and DNA adsorption on surface modified MCM-41 were investigated by FT-IR and UV-Vis spectrometer, respectively. The use of MCM-41 as the modification of electrode surfaces were investigated electrochemical properties of metal mediators with biomolecules. The modified ITO electrodes increased peak currents for a redox process of [Ru(bpy)3]2+ relative to the bare electrode. The electrochemical detection of DNA by cyclic voltammetry when the current is saturated in the presence of the mediator appeared more sensitive due to a higher catalytic current on the MCM-41 supported electrodes modified by carboxylic acid functional groups. The carboxyl or amine groups on the surface of MCM-41 interact and react with the -NH2 groups of guanine and backbone, respectively. Highly ordered mesoporous materials with organic groups could find applications as DNA sensors.
퍼지이론과 베이지안 갱신 기반의 과거 주행정보를 이용한 차량항법 장치의 교통상황 예측과 최적경로 계획
정상준(Sang-Jun Jung),허용관(Yong-Kwan Heo),조한무(Han-Moo Jo),김종진(Jong-Jin Kim),최슬기(Sul-Gi Choi) 한국컴퓨터정보학회 2009 韓國컴퓨터情報學會論文誌 Vol.14 No.11
경제가 성장함에 따라 자동차는 현대인의 생활에 많은 영향을 끼치고 있다. 차량항법장치는 운전자에게 목적지까지의 경로를 안내해 주기 때문에 많은 편의를 제공하고 있다. 그러나 개인의 차량 소유가 대중화됨에 따라 교통혼잡이 발생하지만 차량항법장치는 환경을 고려하지 않는 일방적인 경로를 계획한다. 기존의 차량항법장치는 시간대와 상관없이 출발지와 목적지만 같으면 항상 동일한 경로와 소요시간을 제공하는 한계를 가지고 있다. 본 논문에서는 누적된 과거의 주행정보를 퍼지이론과 베이지안 갱신에 적용하여 교통상황을 예측하고 경로 계획에 반영하는 방법을 제안한다. 퍼지 이론을 통해 과거 주행정보의 출발 시간대와 속도율로 분류하고 베이지안 갱신을 사용하여 각 시간대에서 벌어질 교통상황을 확률로 계산한다. 전자지도에서 출발지와 목적지를 포함한 타원관심영역을 설정하고 Dijkstra와 A* 알고리즘을 융합하여 교통상황을 고려한 최적의 경로를 계획한다. 제안한 알고리즘의 성능과 정확성은 계획된 경로를 실제 주행함으로써 예측된 소요시간과 실제 주행시간을 비교하여 검증하였다. The vehicles play a significant role in modern people's life as economy grows. The development of car navigation system(CNS) provides various convenience because it shows the driver where they are and how to get to the destination from the point of source. However, the existing map-based CNS does not consider any environments such as traffic congestion. Given the same starting point and destination, the system always provides the same route and the required time. This paper proposes a path planning method with traffic prediction by applying historical driving information to the Fuzzy theory and Bayesian update. Fuzzy theory classifies the historical driving information into groups of leaving time and speed rate, and the traffic condition of each time zone is calculated by Bayesian update. An ellipse area including starting and destination points is restricted in order to reduce the calculation time. The accuracy and practicality of the proposed scheme are verified by several experiments and comparisons with real navigation.