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Hwang Euijin,Cho Keunchang,Kim Ho Il,Kim Hasuck Korean Chemical Society 1994 Bulletin of the Korean Chemical Society Vol.15 No.12
Different behavior on the formation of soluble intermediate was observed depending on the substrate employed during the nucleation of lead dioxide from plumbous ion using a rotating ring-disk electrode. It was found that no soluble intermediate was formed at glassy carbon electrode, while the presence of soluble intermediate could be detected at platinum substrate. From the different anodic behavior of two substrates, the formation of a probable Pb(Ⅲ) soluble intermediate was suggested. A most probable nucleation mechanism at the platinum substrate involving a second order chemical reaction was derived on the basis of rotating disk electrode experiments.
Kim, Mira,Ock, Kwangsu,Cho, Keunchang,Joo, Sang-Woo,Lee, So Yeong The Royal Society of Chemistry 2012 Chemical communications Vol.48 No.35
<P>The intracellular glutathione-triggered release of the anticancer drug topotecan from gold nanoparticles in serum-containing media was directly monitored in real time using a label-free fluorescence live-cell imaging technique.</P> <P>Graphic Abstract</P><P>Intracellular glutathione-triggered release of the anticancer drug topotecan from gold nanoparticles in serum-containing media was directly monitored in real time. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc30679d'> </P>
이원구,방현우,한동철,김정아,Keunchang Cho,Chanil Chung,Jun Keun Chang,윤호영 한국물리학회 2008 Current Applied Physics Vol.8 No.6
A systematic design and miniaturization of conventional clinical and diagnostic tools are emerging in many nanobiotechnology and nanobioscience fields. Recently, the pharmaceutical and biotechnological industries have continuously accelerated novel drug discovery for cellular therapeutics of hard-to-cure diseases. Electroporation is a promising candidate in gene transfection methods for future cellular therapeutics. Here, we report our initial study on the effect of geometry on impedance of cell suspended media in electroporation using a microchannel. A full understanding of the electroporation environment and conditions enabled us to optimize protocols of electroporation for various cell lines efficiently. Furthermore, this study will open up a new vista of future electroporation devices using microstructures.
Concentration-dependent fluorescence live-cell imaging and tracking of intracellular nanoparticles
Seo, Ji Hye,Cho, Keunchang,Lee, So Yeong,Joo, Sang-Woo IOP Pub 2011 Nanotechnology Vol.22 No.23
<P>Using live-cell imaging techniques we investigated concentration-dependent intracellular movements of fluorescence nanoparticles (NPs) in real-time after their entry into HeLa cells via incubation. Intracellular particle traces appeared to be a mixture of both random and fairly unidirectional movements of the particles. At rather low concentrations of NPs, a majority of the non-random intracellular particle trajectories are assumed to mostly go along microtubule networks after endocytosis, as evidenced from the inhibition test with nocodazole. On the other hand, as the concentrations of NPs increased, random motions were more frequently observed inside the cells. </P>
Surface tension-enhanced optical trapping for lateral close-packing
이원구,방현우,Hwa Joon Park,Keunchang Cho,Chanil Chung,한동철,Jun Keun Chang 한국물리학회 2006 Current Applied Physics Vol.6 No.1l
Here we present our initial study of a surface tension-enhanced optical trapping for lateral close-packing of dielectric objects. This is anovel approach to optically trap multiple micro-scale objects even with a lower intensity of the beam. Such lateral close-packing by indi-would be contributed to study cell-to-cell interactions and cell fusion dynamics of living cells in nano- and micro-uidic environments.
Asymmetric nozzle structure for particles converging into a highly confined region
Park, Junha,Chung, Seok,Yun, Hoyoung,Cho, Keunchang,Chung, Chanil,Han, Dong-Chul,Chang, Jun Keun Elsevier 2006 CURRENT APPLIED PHYSICS Vol.6 No.6
<P><B>Abstract</B></P><P>Asymmetric nozzle inlet was suggested for particles to converge into a highly confined region. The physical properties from the nano-scaled volumetric difference at nozzle inlet were investigated using computational fluid dynamics and particle motion measurement with fluorescence beads and erythrocytes. The asymmetric nozzle structure made particles converge efficiently without clogging at nozzle inlet. It could be used as a micro/nanofluidic unit for cell based assay in a microchip such as chip-based flow cytometer.</P>
Jang, Yun Hee,Hwang, Sungu,Cho, Keunchang,Lim, Manho,Joo, Taiha,Choi, Suhee,Kim, Jongwon,Joo, Sang‐,Woo John Wiley Sons, Ltd. 2011 Surface and interface analysis Vol.43 No.3
<P><B>Abstract</B></P><P>The potential‐induced adsorption change of 2‐amino‐4,5‐imidazoledicarbonitrile (AIDCN) on Ag electrode surfaces has been examined by surface‐enhanced Raman scattering (SERS) in an applied potential range between −1.0 and 0.2 V. Upon adsorption, AIDCN has a substantial interaction with the Ag metal surfaces via its two nitrile groups. The CN stretching peaks at ∼2200 cm<SUP>−1</SUP> appeared to be more intensified and redshifted at a negative potential. The deconvolution peak analysis of the CN bands at various voltages suggests that there should be a change in binding modes of AIDCN on Ag surfaces. This potential‐dependent orientation change appeared to be reversible. The density functional theory (DFT) calculation of AIDCN on Ag cluster atoms is used to explain its potential‐dependent adsorption. Copyright © 2010 John Wiley & Sons, Ltd.</P>