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      • Stimuli-Induced Equilibrium Point: A Psychological Field Theory Application in Ramp Merging Systems

        Kendrick Amezquita S.,Peter C. Y. Chen,Weihai Chen,Zheng Zhao 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10

        Based on the psychological field theory, the stimuli-induced equilibrium point (SIEP) model is formulated to characterize the interaction of a driver between two vehicles (leader and follower) in a three-vehicle platooning configuration. Considering the intensity of the stimuli that act upon a driver between these vehicles, the point at which the stimuli resultant becomes zero (i.e. the equilibrium point) is obtained. Consequently, the location of such a point within the leader-follower gap changes continuously according to the speed of the middle vehicle and the current traffic scenario. This methodology enables the systematic computation of speed and position references for automatic ramp merging systems. Such stimuli-induced equilibrium point has shown to improve the performance of existing merging control schemes while increasing safety conditions by providing enough reaction time for drivers to avoid and eventual collision.

      • Cytoplasmic polyadenylation element-binding protein regulates neurotrophin-3-dependent beta-catenin mRNA translation in developing hippocampal neurons.

        Kundel, Mitchell,Jones, Kendrick J,Shin, Chan Y,Wells, David G The Society 2009 The Journal of neuroscience Vol.29 No.43

        <P>Neuronal morphogenesis, the growth and arborization of neuronal processes, is an essential component of brain development. Two important but seemingly disparate components regulating neuronal morphology have previously been described. In the hippocampus, neurotrophins, particularly brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3), act to enhance cell growth and branching, while activity-induced branching was shown to be dependent upon intracellular beta-catenin. We now describe a molecular link between NT3 stimulation and beta-catenin increase in developing neurons and demonstrate that this process is required for the NT3-mediated increase in process branching. Here, we show that beta-catenin is rapidly increased specifically in growth cones following NT3 stimulation. This increase in beta-catenin is protein synthesis dependent and requires the activity of cytoplasmic polyadenylation element-binding protein-1 (CPEB1), an mRNA-binding protein that regulates mRNA translation. We find that CPEB1 protein binds beta-catenin mRNA in a CPE-dependent manner and that both localize to growth cones of developing hippocampal neurons. Both the NT3-mediated rapid increase in beta-catenin and process branching are abolished when CPEB1 function is inhibited. In addition, the NT3-mediated increase in beta-catenin in growth cones is dependent upon internal calcium and the activity of CaMKII (calcium/calmodulin-dependent kinase II). Together, these results suggest that CPEB1 regulates beta-catenin synthesis in neurons and may contribute to neuronal morphogenesis.</P>

      • KCI등재

        Anesthesia care provider sedation versus conscious sedation for endoscopic ultrasound–guided tissue acquisition: a retrospective cohort study

        Sneha Shaha,Yinglin Gao,Jiahao Peng,Kendrick Che,John J. Kim,Wasseem Skef 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.5

        Background/Aims: We aimed to study the effects of sedation on endoscopic ultrasound-guided tissue acquisition. Methods: We conducted a retrospective study evaluating the role of sedation in endoscopic ultrasound-guided tissue acquisition bycomparing two groups: anesthesia care provider (ACP) sedation and endoscopist-directed conscious sedation (CS). Results: Technical success was achieved in 219/233 (94.0%) in the ACP group and 114/136 (83.8%) in the CS group (p=0.0086). Inmultivariate analysis, the difference in technical success between the two groups was not significant (adjusted odds ratio [aOR], 0.5;95% confidence interval [CI], 0.234–1.069; p=0.0738). A successful diagnostic yield was present in 146/196 (74.5%) in the ACP groupand 66/106 (62.3%) in the CS group, respectively (p=0.0274). In multivariate analysis, the difference in diagnostic yield between thetwo groups was not significant (aOR, 0.643; 95% CI, 0.356–1.159; p=0.142). A total of 33 adverse events (AEs) were observed. The incidenceof AEs was significantly lower in the CS group (5/33 CS vs. 28/33 ACP; OR, 0.281; 95% CI, 0.095–0.833; p=0.022). Conclusions: CS provided equivalent technical success and diagnostic yield for malignancy in endoscopic ultrasound-guided tissueacquisition. Increased AEs were associated with anesthesia for the endoscopic ultrasound–guided tissue acquisition.

      • KCI등재

        Association between Inflammatory Bowel Disease and Lactose Intolerance: Fact or Fiction

        Mohammad Maysara Asfari,Muhammad Talal Sarmini,Katherine Kendrick,Amit Hudgi,Pearl Uy,Subbaramiah Sridhar,Humberto Sifuentes 대한소화기학회 2020 대한소화기학회지 Vol.76 No.4

        Background/Aims: Inflammatory bowel disease (IBD) is a complex condition precipitated by genetic susceptibility and possibly a disturbed microbiome. The role of dairy foods in IBD is controversial. This study examined the association between lactose intolerance (LI) and IBD. Methods: Data on hospital admissions of all IBD adult patients were extracted from the National Inpatient Sample database between 2004 and 2014. The comorbidities and outcomes of interest were defined by querying all the diagnostic and procedural fields for the corresponding International Classification of Diseases 9th version (ICD-9) codes. Patients with IBD were defined as the “study group,” and the patients who did not have IBD were defined as the “control group”. LI was identified in both groups using the ICD-9 codes. Multivariate logistic regression was performed to examine the association between IBD and LI. Results: The total population was 71,342,237 patients, of which 598,129 (0.83%) had IBD. The IBD patients were younger (52 years vs. 57 years) and with fewer females (57.5% vs. 60.1%) (p<0.001 for all). After adjusting for the potential confounding factors, the IBD group had a significantly higher rate of LI (OR 2.71, 95% CI 2.55-2.88, p<0.001) compared to the non-IBD group. The findings were similar on the further stratification of IBD into Crohn’s disease compared to the control group (OR 2.70, 95% CI 2.50-2.92, p<0.001) and ulcerative colitis compared to the control group (OR 2.71, 95% CI 2.46-2.98, p<0.001). Conclusions: IBD patients have a 2.7 times higher risk of LI. Screening for LI in this population is warranted to avoid confusing or overlapping symptomatology.

      • SCIESCOPUSKCI등재

        Development of TREND dynamics code for molten salt reactors

        Yu, Wen,Ruan, Jian,He, Long,Kendrick, James,Zou, Yang,Xu, Hongjie Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.2

        The Molten Salt Reactor (MSR), one of the six advanced reactor types of the 4th generation nuclear energy systems, has many impressive features including economic advantages, inherent safety and nuclear non-proliferation. This paper introduces a system analysis code named TREND, which is developed and used for the steady and transient simulation of MSRs. The TREND code calculates the distributions of pressure, velocity and temperature of single-phase flows by solving the conservation equations of mass, momentum and energy, along with a fluid state equation. Heat structures coupled with the fluid dynamics model is sufficient to meet the demands of modeling MSR system-level thermal-hydraulics. The core power is based on the point reactor neutron kinetics model calculated by the typical Runge-Kutta method. An incremental PID controller is inserted to adjust the operation behaviors. The verification and validation of the TREND code have been carried out in two aspects: detailed code-to-code comparison with established thermal-hydraulic system codes such as RELAP5, and validation with the experimental data from MSRE and the CIET facility (the University of California, Berkeley's Compact Integral Effects Test facility).The results indicate that TREND can be used in analyzing the transient behaviors of MSRs and will be improved by validating with more experimental results with the support of SINAP.

      • KCI등재후보

        Modification of electrical conductivity in RF magnetron sputtered ZnO films by low-energy hydrogen ion implantation

        J. Kennedy,A. Markwitz,Z. Li, W. Gao,C. Kendrick,S.M. Durbin,R. Reeves 한국물리학회 2006 Current Applied Physics Vol.6 No.3

        The electrical conductivity of ZnO lms deposited on Si by the RF sputtering technique were modied by low-energy hydrogen· 1016 to 1.0· 1017 ions cm. 2.High resolution quantitative hydrogen depth proles of the un-doped and doped samples were measured non-destructively with elasticrecoil detection analysis using a nely focussed 2.5 MeV4He+ ion beam impinging onto the samples at 20.surements were carried out on the lms by SEM, XRD and Hall probe measurements to explore the eects of hydrogen implantation. Itwas observed that the electrical conductivity is decreased by as much as an order of magnitude after hydrogen implantation. The lmsremained polycrystalline after implantation. The results suggest that reducing the n-type conductivity using low-energy hydrogen implan-tation without annealing may provide a pathway for passivating the donors for a possible subsequent formation of p-type acceptors byion implantation.

      • SCIESCOPUS

        Design, analysis, and control of a variable electromotive-force generator with an adjustable overlap between the rotor and the stator

        Zhu, W.D.,Goudarzi, N.,Wang, X.F.,Kendrick, P. Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.22 No.2

        A variable electromotive-force generator (VEG), which is a modified generator with an adjustable overlap between the rotor and the stator, is proposed to expand the operational range of a regular generator through a simple and robust active control strategy. It has a broad range of applications in hybrid vehicles, wind turbines, water turbines, and similar technologies. A mathematical model of the VEG is developed, and a novel prototype is designed and fabricated. The performance of the VEG with an active control system, which adjusts the overlap ratio based on the desired output power at different rotor speeds for a specific application, is theoretically and experimentally studied. The results show that reducing the overlap between the rotor and the stator of the generator results in reduced torque loss of the generator and an increased rotational speed of the generator rotor. A VEG can improve the fuel efficiency of hybrid vehicles; it can also expand operational ranges of wind turbines and water turbines and harness more power.

      • KCI등재

        Design, analysis, and control of a variable electromotive-force generator with an adjustable overlap between the rotor and the stator

        W.D. Zhu,N. Goudarzi,X.F. Wang,P. Kendrick 국제구조공학회 2018 Smart Structures and Systems, An International Jou Vol.22 No.2

        A variable electromotive-force generator (VEG), which is a modified generator with an adjustable overlap between the rotor and the stator, is proposed to expand the operational range of a regular generator through a simple and robust active control strategy. It has a broad range of applications in hybrid vehicles, wind turbines, water turbines, and similar technologies. A mathematical model of the VEG is developed, and a novel prototype is designed and fabricated. The performance of the VEG with an active control system, which adjusts the overlap ratio based on the desired output power at different rotor speeds for a specific application, is theoretically and experimentally studied. The results show that reducing the overlap between the rotor and the stator of the generator results in reduced torque loss of the generator and an increased rotational speed of the generator rotor. A VEG can improve the fuel efficiency of hybrid vehicles; it can also expand operational ranges of wind turbines and water turbines and harness more power.

      • KCI등재

        Stable isotopes of Lithosiini and lichens in Hong Kong show the biodindicator potential of lichenivorous moths

        Caren P. Shin,Abby Hoffman,Wanyi Lee,Roger C. Kendrick,David M. Baker,Timothy C. Bonebrake 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.4

        Urban landscapes provide unique environments for a wide variety of plants and animals, but their suitability may be limited by anthropogenic impacts such as pollution. We examined the potential utility of lichen and lichen-feeding moths as biodindicators of air pollution in Hong Kong by comparing carbon (C) and nitrogen (N) stable isotope values in lichens, lichenivorous and non-lichenivorous moths (Lepidoptera: Erebidae) and a moth outgroup (Lepidoptera: Geometridae). Our results show that stable isotope values for C and N were similar for lichens and lichen feeding moths, while non-lichen feeding moths formed a distinct group. In addition, we found consistent δ 13 C and δ 15 N values across moth body parts, indicating that any portion of the specimen is suitable for isotopic fingerprinting. Our results highlight that lichen feeding moths may be useful for integrating signals of atmospheric nitrogen pollution and could therefore have utility in monitoring and quantifying air quality over time and space.

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