Three-dimensional analysis of the arrangement of microtubules of the outer segment in the ciliary-type photoreceptor cell in the Onchidium dorsal eye

Katagiri, Nobuko,Shimatani, Yuichi,Katagiri, Yasuo Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2

The inverted retina of the Onchidium dorsal eye (DE) is composed only of ciliary-type photoreceptor cells (CC's). The outer segment (OS) of the CC is a concentric lamellar structure consisting of many modified ciliary membranes and stains positively with anti-$\beta$-tubulin antibody. Near the base of the OS there are about 30 basal bodies each connecting individually to a cilium. The cilia are rod-shaped at the base, progressing upwards to a flattened sheet-like shape with increasing surface area. Three-dimensional analysis on serial sections demonstrates the ladle-shape of a modified cilium. Many modified cilia wrap around each other like the leaves of a cabbage. Nine pairs of microtubules (MT's) are located regularly in a ring at the base of the cilium, gradually losing their regular arrangement towards the periphery, where they separate into two subgroups that are contained within two swollen portions of a modified cilium. Within the CC of the Onchidium DE, MT's in the modified cilium exist as two poles extending longitudinally in a thin expanded ciliary membrane. This arrangement may support the photoreceptive OS and serve to maintain its structural integrity.

兒童虐待に關する判例硏究

( Katagiri Yuki ) 아세아여성법학연구소 2002 아세아여성법학 Vol.5 No.-

In recent years, the increase of child abuse has been featured in the mass media. This is one of hot issue in the field of Social Security Law. Most of child abuse are done by the person with parental authority. Against such a situation, we have some legislations in Japan. Child Welfare Law plays the most important role, and when the case is so serious, the Penal Code can be applied. For dealing with the increase of child abuse, the Law concerning the Prevention of Child Abuse on May 2000. Our actual condition of Child Abuse is as follows. There were l7, 725 consultations(2000) to the child guidance center. The breakdown is physical abuse (49.7%), neglect (36.5) %, sexual abuse(3.7%) and emotional abuse(l0.l%) in 2000. These are done by mother (6L6%), farter (23.7%), stepmother and stepfather followed them. In the case of child abuse, it is desirable to separate the child and their parent. The child Welfare Law provides the some institutions for child who was separated from their parent (§ 27(1)-3). Then the consent from the parent is indispensable far sending the child to the institutions. Bar without this consent, they can send the child there after getting the approval from Family Court(Child Welfare Law § 28). There were 142 applications for the approval in 2000 and 10 1 of them were accepted, When the Child abuse is very serious, the director of child guidance center can ask the loss sentence parental authority for Family Court( § 33-6). In the case for asking the approval on the Child Welfare Law § 28, there are some regal issue. At first, it is whether Family Court can give the comprehensive approval or nor. Concerning this problem, some gave the comprehensive approval, but in most of cases, Family Court expressed the concrete referral. The judgement of the Court of Appeal in fukuoka 1989/4/28 is the leading case in this point. It is not a final solution to separate the .child from their parent. We can say it is the act of necessity. The ultimate goal is reproduction of family. For this purpose, Child Welfare Law § 27(1)-2 provides that the child welfare officer give instruction to the child and parent. Through this article, We can hope they learn how to make a good relationship between them. In addition, the Law concerning the Prevention of Child Abuse provides the heating from the child welfare officer as an important marter of referral rescission. In the cases, we can see some judge expects such an instruction by the child guidance center. Lastly 1 would like to dose this paper by pointing out this. It is that on solving the child abuse, we may not make use of the judiciary proceedings. As stated above, although the number of consultation on child abuse is about 18.000, the application to Family Coon is only 142. We can say this is the reason why most of them are solved at the level of child guidance center. Bur we can also indicate some child guidance center hesitate to apply to Family Court and some Family Court show a negative attitude toward the accept of such an application. Considering the important role of the law playing on relief of child abuse, we should actively use the judiciary proceedings in future.

Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells

Katagiri, Wataru,Kawai, Takamasa,Osugi, Masashi,Sugimura-Wakayama, Yukiko,Sakaguchi, Kohei,Kojima, Taku,Kobayashi, Tadaharu Korean Association of Maxillofacial Plastic and Re 2017 Maxillofacial Plastic Reconstructive Surgery Vol.39 No.-

Background: For an effective bone graft for reconstruction of the maxillofacial region, an adequate vascular network will be required to supply blood, osteoprogenitor cells, and growth factors. We previously reported that the secretomes of bone marrow-derived mesenchymal stem cells (MSC-CM) contain numerous growth factors such as insulin-like growth factor (IGF)-1, transforming growth factor $(TGF)-{\beta}1$, and vascular endothelial growth factor (VEGF), which can affect the cellular characteristics and behavior of regenerating bone cells. We hypothesized that angiogenesis is an important step for bone regeneration, and VEGF is one of the crucial factors in MSC-CM that would enhance its osteogenic potential. In the present study, we focused on VEGF in MSC-CM and evaluated the angiogenic and osteogenic potentials of MSC-CM for bone regeneration. Methods: Cytokines in MSC-CM were measured by enzyme-linked immunosorbent assay (ELISA). Human umbilical vein endothelial cells (HUVECs) were cultured with MSC-CM or MSC-CM with anti-VEGF antibody (MSC-CM + anti-VEGF) for neutralization, and tube formation was evaluated. For the evaluation of bone and blood vessel formation with micro-computed tomography (micro-CT) and for the histological and immunohistochemical analyses, a rat calvarial bone defect model was used. Results: The concentrations of IGF-1, VEGF, and $TGF-{\beta}1$ in MSC-CM were $1515.6{\pm}211.8pg/mL$, $465.8{\pm}108.8pg/mL$, and $339.8{\pm}14.4pg/mL$, respectively. Tube formation of HUVECs, bone formation, and blood vessel formation were increased in the MSC-CM group but decreased in the MSC-CM + anti-VEGF group. Histological findings suggested that new bone formation in the entire defect was observed in the MSC-CM group although it was decreased in the MSC-CM + anti-VEGF group. Immunohistochemistry indicated that angiogenesis and migration of endogenous stem cells were much more abundant in the MSC-CM group than in the MSC-CM + anti-VEGF group. Conclusions: VEGF is considered a crucial factor in MSC-CM, and MSC-CM is proposed to be an adequate therapeutic agent for bone regeneration with angiogenesis.

社會保障制度における不正受給 -生活保護を中心に-

( Katagiri Yuki ) 아세아여성법학회 2013 아세아여성법학 Vol.16 No.-

The Social Security fund was made of our tax and premium. So, the nature is very public and we are forbidden to receive social security benefit on the base of wrong ways. Public assistant system is funded by 100% tax and there is strict means test before getting the assistance. In this system, trouble on wrong way is sometimes caused by gap of understanding it between the government and recipient. The government prohibit recipient has a car in general. When authority finds out recipient has a car, it give recipient legal sanction, that`s suspension or cancel of public assistance. In the case, the law requires the authority should observe Due Process. It means that when authority gives a sanction, at first the sanction has to be the mildest one. In Social Security system, legal sanction must be taken carefully, keep Due Process and have a regard for recipients.

Sub-Terahertz Optical Pulse Sources Utilizing Harmonic Colliding-Pulse Mode-Locked Semiconductor Lasers with Periodic Absorber Configuration

Yoshitada Katagiri,Atsushi Takada 한국통신학회 1997 OPTOELECTRONICS & COMMUNICATIONS CONFERENCE Vol.2 No.1

주택보장제도의 현대적 과제

片桐由喜 ( Katagiri Yuki ) 아세아여성법학회 2021 아세아여성법학 Vol.24 No.-

주택은 인간 생활의 기반이며 개인의 자율적 삶을 영위하는 데 필요한 공간이다. 그런데도 현 상황은 기업이나 가족에 의지하는 부분이 크며 공적인 주택 보장은 충분하지 않다. 이러한 가운데 2021년 현재, 신종 코로나바이러스 감염 방지 대책을 통한 경제 활동의 강제적인 자숙으로 인해 많은 노동자들은 수입이 줄어들거나 실직으로 인해 곤경에 처해 있다. 그 결과 주택을 잃었거나 잃을 위기에 처한 사람도 있으나 충분한 공적 지원을 받을 수 없는 상황이다. 이번 코로나 사태를 계기로 일본의 취약한 공적 주택보장제도가 표면에 드러났다. 앞으로는 주택 공급에 대한 공적 관여를 강화하고 보편적인 주택보장제도를 정비해 나갈 것이 요구된다. Housing is the base of human life. Nevertheless, we highly depend on private sector, that is the companies or families, for the housing. Because the public responsibility, which means Governmental responsibility, for housing is not sufficient. By the way, as of 2021, many workers are suffering from reduced income or unemployment due to restraining the economic activities forced to prevent infection with the COVID-19. Now, due to reduced income or unemployment, some have lost or are at risk of losing their homes but have not received sufficient housing benefit from public sector. And by (thanks to) COVID-19, we noticed the weakness of public housing benefit in Japan. In the future, it will be necessary to strengthen public involvement in housing supply and develop a universal housing benefit.

공적연금제도의 공정한 부담 ―새로운 노동스타일에 대한 대응―

片桐由喜 ( Katagiri Yuki ) 아세아여성법학연구소 2017 아세아여성법학 Vol.20 No.-

公的年金制度는 私的扶養能力이 저하한 오늘날 國民의 老後所得保障으로서 지극히 重要한 역할을 하게 되었다. 同制度는 일본을 포함해 많은 국가에서 强制加入 社會保險方式을 採用하여 保險料납부가 年金受給要件이다. 이 保險料가 保險財源을 形成하여 國民의 상호공조(相互共助)를 가능하게 하고 있다. 모두가 똑같이 부담해야 되기 때문에 年金制度는 누구에게든지 공평하고 중립적인 성격을 가져야 한다. 그럼에도 불구하고 日本年金制度에 대한 각각의 당사자가 적지 않은 불공평감을 안고 있어 제도에 대한 불만을 일으키게 하고 있다. 특히 그 불공평감은 非正規勞動者와 正規勞動者 사이 full-time 女性노동자와 parttime으로 일하는 주부 사이에서 크다. 또한 최근에는 생계유지가 아닌 사회공헌이나 자기의 능력 발휘의 기회를 찾아 활동하여 報酬를 얻는 새로운 work style이 등장하면서 새로운 문제가 나타났다. 그러나 이러한 현상은 서구에서는 볼 수 없다. 즉, 雇用形態나 旣婚未婚 또는 연수입으로 연금제도 내에서 피보험자자격이 다른 현상은 매우 일본적이다. 서구의 제도구조는 사회보험 원칙에 충실하고 무엇보다 simple해서 누구에게든 이해하기가 쉽다. 본고는 일본 연금제도에 내재한 상기와 같은 일본적인 특징이 과연 합리적인지를 검토하고, 상기에서 제시한 새로운 work style을 연금제도 안에서 어떻게 평가해야할 것인가를 제도구조의 공평성 측면을 염두에 두고 생각하자고 한다. 본고는 公的年金制度 適用範圍擴大의 沿革을 개관하고(1), 그다음으로 근년의 증가하고 있는 非正規雇用勞動者의 年金適用關係를 살펴보고(2), 雇用이라는 형태를 취하지 않는 work style에는 公的年金制度가 어떻게 대응해야 할 것인가를 검토한다(3). 이 작업이 향후 같은 문제를 떠안을지도 모를 한국에 참고가 되면 다행이다. The Japanese public pension system makes up for a drop of the ability for family support now. Therefore the system take a very important role as the income security for, especially, the old age. Person insured qualification varies according to an occupation; Self-employed workers, employees, and their dependents. In addition, the insured qualification also depend on regular employees or non-regular employees, married or unmarried, and annual income. Against such a system, the criticism that this is an unfair design as the public system exists for a long time. By the way, recently, not for living, a new style of working for social contribution and/or exerting the best of their abilities has appeared, that is activity at the organization, Workers’ Collective. This organization doesn’t seek to make a profit. They aim to provide vulnerable groups, the aged, children and disabled, in their community with service by the price lower than market price. For example, the kind of services is a baby-sitter, food delivery and so on. Now the government wants the directors of Workers’ Collective to pay the pension premiums on the reason that they get the reward for working at the organizations. But the directors of Workers’ Collective assert that they are not employees in general, but are the same as the dependents of employees. These features are unique to Public Pension System in Japan. In other words, people can choice more profitable qualification for them. Such a situation cause to feel lack of impartial and neutral. In this paper, I will overview the outline of Japanese Public Pension System and look at way what the System should be.

Recent Topics in Fibrodysplasia Ossificans Progressiva

Takenobu Katagiri,Sho Tsukamoto,Yutaka Nakachi,Mai Kuratani 대한내분비학회 2018 Endocrinology and metabolism Vol.33 No.3

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissuesin soft tissues, such as skeletal muscle, ligament, and tendon. It is difficult to remove such heterotopic bones via internal medicineor invasive procedures. The identification of activin A receptor, type I (ACVR1)/ALK2 gene mutations associated with FOP hasallowed the genetic diagnosis of FOP. The ACVR1/ALK2 gene encodes the ALK2 protein, which is a transmembrane kinase receptorin the transforming growth factor-β family. The relevant mutations activate intracellular signaling in vitro and induce heterotopicbone formation in vivo. Activin A is a potential ligand that activates mutant ALK2 but not wild-type ALK2. Various types of smallchemical and biological inhibitors of ALK2 signaling have been developed to establish treatments for FOP. Some of these are inclinical trials in patients with FOP.

A Study on Radiation Risk Recognition Aided System Visualizing Risk Information by CG

M. Katagiri,Y. Tuzuki,S. Sawamura,Y. Aoki 대한전자공학회 2002 ITC-CSCC :International Technical Conference on Ci Vol.2002 No.7

Analysis using the data from ground-based observations at Fukue-Isle, such as spectro-radiometer, grating sunphotometer and CIR4, etc.

Shuichiro Katagiri,Nobuyuki Kikuchi,Kiyotaka Uchida,Tadahiro Hayasaka 한국기상학회 2006 한국기상학회 학술대회 논문집 Vol.2006 No.-