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Shilabant Sen Sribastav,Jun Long,Peiheng He,Wei He,Fubiao Ye,Zemin Li,Jianru Wang,Hui Liu,Hua Wang,Zhaomin Zheng 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.3
Study Design: A prospective cross-sectional study. Purpose: To evaluate the risk factors associated with the severity of pain intensity in patients with non-specific low back pain (NSLBP) in Southern China. Overview of Literature: Low back pain (LBP) is the leading cause of activity limitation and work absence throughout the world, so a firm understanding of the risk factor associated with NSLBP can provide early and prompt interventions that are aimed at attaining long-term results. Methods: Participants were recruited from January 2014 to January 2016 and were surveyed using a self-designed questionnaire. Anonymous assessments included Short Form 36-Item Health Survey (SF-36) and Visual Analogue Scale (VAS). The association between the severity of NSLBP and these potential risk factors were evaluated. Results: A total of 1,046 NSLBP patients were enrolled. The patients with primary school education, high body mass index (BMI), those exposed to sustained durations of driving and sitting, smoking, recurrent LBP had increased VAS and Oswestry Disability Index (ODI) scores with lower SF-36 scores (p <0.01). Workers and drivers compared with waiters and patients who lifted >10 kg objects in a quarter of their work time for >10 years had higher VAS and ODI scores with lower SF-36 scores (p <0.01). Multiple logistic regression showed lower levels of education, LBP for 1–7 days, long-lasting LBP in last year, smoking, long duration driving, and higher BMI were associated with more severe VAS score. Conclusions: The severity of NSLBP is associated with lower levels of education, poor standards of living, heavy physical labor, long duration driving, and sedentary lifestyle. Patients with recurrent NSLBP have more severe pain. Reducing rates of obesity, the duration of heavy physical work, driving or riding, and attenuating the prevalence of sedentary lifestyles and smoking may reduce the prevalence of NSLBP.
Roles of NMDA NR2B Subtype Receptor in Prefrontal Long-Term Potentiation and Contextual Fear Memory
Zhao, Ming-Gao,Toyoda, Hiroki,Lee, Yong-Seok,Wu, Long-Jun,Ko, Shanelle W.,Zhang, Xue-Han,Jia, Yongheng,Shum, Fanny,Xu, Hui,Li, Bao-Ming,Kaang, Bong-Kiun,Zhuo, Min Elsevier 2005 Neuron Vol.47 No.6
<P><B>Summary</B></P><P>Cortical plasticity is thought to be important for the establishment, consolidation, and retrieval of permanent memory. Hippocampal long-term potentiation (LTP), a cellular mechanism of learning and memory, requires the activation of glutamate N-methyl-D-aspartate (NMDA) receptors. In particular, it has been suggested that NR2A-containing NMDA receptors are involved in LTP induction, whereas NR2B-containing receptors are involved in LTD induction in the hippocampus. However, LTP in the prefrontal cortex is less well characterized than in the hippocampus. Here we report that the activation of the NR2B and NR2A subunits of the NMDA receptor is critical for the induction of cingulate LTP, regardless of the induction protocol. Furthermore, pharmacological or genetic blockade of the NR2B subunit in the cingulate cortex impaired the formation of early contextual fear memory. Our results demonstrate that the NR2B subunit of the NMDA receptor in the prefrontal cortex is critically involved in both LTP and contextual memory.</P>
Thermodynamic simulation and structural optimization of the collimator in the drift duct of EAST-NBI
Tang Ning,Hu Chun-dong,Xie Yuan-lai,Wei Jiang-long,Cui Zhi-Wei,Xie Jun-Wei,Pan Zhuo,Jiang Yao 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.11
The collimator is one of the high-heat-flux components used to avoid a series of vacuum and thermal problems. In this paper, the heat load distribution throughout the collimator is first calculated through experimental data, and a transient thermodynamic simulation analysis of the original model is carried out. The error of the pipe outlet temperature between the simulated and experimental values is 1.632%, indicating that the simulation result is reliable. Second, the model is optimized to improve the heat transfer performance of the collimator, including the contact mode between the pipe and the flange, the pipe material and the addition of a twisted tape in the pipe. It is concluded that the convective heat transfer coefficient of the optimized model is increased by 15.381% and the maximum wall temperature is reduced by 16.415%; thus, the heat transfer capacity of the optimized model is effectively improved. Third, to adapt the long-pulse steady-state operation of the experimental advanced superconducting Tokamak (EAST) in the future, steady-state simulations of the original and optimized collimators are carried out. The results show that the maximum temperature of the optimized model is reduced by 37.864% compared with that of the original model. The optimized model was changed as little as possible to obtain a better heat exchange structure on the premise of ensuring the consumption of the same mass flow rate of water so that the collimator can adapt to operational environments with higher heat fluxes and long pulses in the future. These research methods also provide a reference for the future design of components under high-energy and long-pulse operational conditions
A Wearable ECG Acquisition System With Compact Planar-Fashionable Circuit Board-Based Shirt
Yoo, J.,Long Yan,Seulki Lee,Hyejung Kim,Hoi-Jun Yoo IEEE 2009 IEEE transactions on information technology in bio Vol.13 No.6
<P>A wearable electrocardiogram (ECG) acquisition system implemented with planar-fashionable circuit board (P-FCB)-based shirt is presented. The proposed system removes cumbersome wires from conventional Holter monitor system for convenience. Dry electrodes screen-printed directly on fabric enables long-term monitoring without skin irritation. The ECG monitoring shirt exploits a monitoring chip with a group of electrodes around the body, and both the electrodes and the interconnection are implemented using P-FCB to enhance wearability and to lower production cost. The characteristics of P-FCB electrode are shown, and the prototype hardware is implemented to successfully verify the proposed concept.</P>
Xu-Yang Wang,Da-Jun Yuan,Da-Long Jin,Wei-Lin Su 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.5
In the long-distance shield tunneling process, the shield tail brush needs to be replaced after wear failure, especially in cross-river and cross-sea tunnel projects. Taking the shield tail brush replacement project of Qingchun Road tunnel in Hangzhou, China as the research background, a three-dimensional sequential thermo-mechanical coupled numerical simulation was carried out to study the shield tail brush replacement with liquid nitrogen freezing by ABAQUS software. The development of temperature fields and displacement fields of soil, and the deformations of the tunnel sections along the longitudinal direction induced by freezing were obtained. The numerical model was further validated by site measurement. In addition, the effects of the frozen wall thickness, buried depth, excavation radius, and coefficients of linear thermal expansion of soils on the frost heave were studied.
Yuan Liu,Yanmei Liao,Yintao Long,Yuxiang Qian,Shengqiang Nie,Yi Wang,Jia Zeng,Chunmei Zhang,Linbo Tian,Jun Luo 한국고분자학회 2022 폴리머 Vol.46 No.3
It is a considerable challenge for expanding the applications of self-healing polyurethane because of the dilemma in balancing its mechanical and self-healing properties. Herein, a series of self-healing polyurethane systems (PUT-x) with short-range ordered rigid aromatic structures were synthesized by simply adjusting two kinds of diisocyanates, and by ingenious addition of aromatic chain extender. We hope to regulate the π-π interactions and further to manipulate the properties of obtained polyurethanes via adjusting the amount of the benzene rings in the molecular chains of the PUT-x systems. The PUT-5 with decent self-healing ability, optimal mechanical properties, acceptable thermal stability and favorable transparency was selected to incorporate liquid metal and fluorescent powder to fabricate conductive wire and anti-counterfeiting film. Significantly, the liquid metal could be recycled from the conductive wire conveniently without using strong acids or strong bases. Moreover, PUT-5 exemplarily withstood long-term soaking in normal saline, and no deformation could be identified.
( Jing Wang ),( Wei Chen ),( Fang Wang ),( Dong Wu ),( Jia Ming Qian ),( Jun Ren Kang ),( Hai Long Li ),( En Ling Ma ) 한국임상영양학회 2015 Clinical Nutrition Research Vol.4 No.2
Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is characterized by significant gastrointestinal dysmotility. Early and long-term nutritional therapy is highly recommended. We report a case of MNGIE in a patient who was undergoing longterm nutrition therapy. The patient was diagnosed with a serious symptom of fatty liver and hyperlipidemia complications, along with homozygous mutation of the thymidine phosphorylase (TYMP) gene (c.217G > A). To our knowledge, this is the first report of such a case. Herein, we describe preventive measures for the aforementioned complications and mitochondrial disease-specific nutritional therapy.
Study on Bearing Life Calculation for Wind Turbine Gearbox
Long-jun Liang(양용군),Chang Choi(최창),Qi Zhang(장기),Zhe-Zhu Xu(허철수),Sung-ki Lyu(류성기) 한국기계가공학회 2014 한국기계가공학회지 Vol.13 No.5
Currently, wind power has become a major research field in the area of sustainable development. As one important component of a wind turbine transmission system, most instances of downtime due to a gearbox failure are caused by bearing failures. Gearboxes for wind turbines must have the highest levels of reliability over a period of approximately 20 years, withstanding high dynamic loads. At the same time, a lightweight design and cost minimization efforts are required. These demands can only be met with a well-thought-out design, high-quality materials, a high production quality and proper maintenance. In order to design a reliable and lightweight gearbox, it is necessary to analyze methods pertaining to the bearing rating lifetimes of the standard and of different companies, also including calculation methods for modification factors. This can determine the influence of the bearing lifetime.
Probabilistic Prediction of Stability of Ship by Risk Based Approach
Long, Zhan-Jun,Lee, Seung-Keon,Lee, Sung-Jong,Jeong, Jae-Hun Korean Institute of Navigation and Port Research 2009 한국항해항만학회지 Vol.33 No.4
Prediction of the stability for ships is very complex in reality. In this paper, risk based approach is applied to predict the probability of capsize for a certified ship, which is effected by the forces of sea especially the wave loading Safety assessment and risk analysis process are also applied for the probabilistic prediction of stability for ships. The probability of shipsencountering different waves at sea is calculated by the existed statistics data and risk based models. Finally, ship capsizing probability is calculated according to single degree of freedom(SDF) rolling differential equation and basin erosion theory of nonlinear dynamics. Calculation results show that the survival probabilities of ship excited by the forces of the seas, especially in the beam seas status, can be predicted by the risk based method.