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      • KCI등재

        Two mitogenomes in Gruiformes (Amaurornis akool/A. phoenicurus) and the phylogenetic placement of Rallidae

        Jie Gong,Ling Huang,Ruoping Zhao,Qingrong Huang,Xiaomin Sun,Mei-dong Jing 한국유전학회 2017 Genes & Genomics Vol.39 No.9

        Rallidae, with 34 genera including 142 species, is the largest family in the Gruiformes, the phylogenetic placement of this family was still in debate. The complete mitochondrial genomes (mitogenomes), with many advantageous characters, have become popular markers in phylogenetic analyses. We sequenced the mitogenomes of brown crake (Amaurornis akool) and white-breasted waterhen (Amaurornis phoenicurus), analyzed the genomic characters of mitogenomes in Rallidae, and explored the phylogenetic relationships between Rallidae and other four families in Gruiformes based on mitogenome sequences of 32 species with Bayesian method. The mitogenome of A. akool/A. phoenicurus was 16,950/17,213 bp in length, and contained 37 genes typical to avian mitogenomes and one control region, respectively. The genomic characters of mitogenomes in Rallidae were similar. The phylogenetic results indicated that, among five families, Rallidae had closest relationship with Heliornithidae, which formed a sister taxa to Gruidae, while Rhynochetidae located in the basal lineage. Within Rallidae, Rallina was ancestral clade. Gallirallus & Rallus and Aramides were closely related, Gallicrex & Amaurornis and Fulica & Gallinula had close relationships, and these two taxa formed a sister clade to Porphyrio & Coturnicops. Our phylogenetic analyses provided solid evidence for the phylogenetic placement of Rallidae and the evolutionary relationships among different genus within this family. In addition, the mitogenome data presented here provide useful information for further molecular systematic investigations on Gruiformes as well as conservation biology research of these species.

      • SCOPUSKCI등재

        Accelerating the Sweep3D for a Graphic Processor Unit

        Gong, Chunye,Liu, Jie,Chen, Haitao,Xie, Jing,Gong, Zhenghu Korea Information Processing Society 2011 Journal of information processing systems Vol.7 No.1

        As a powerful and flexible processor, the Graphic Processing Unit (GPU) can offer a great faculty in solving many high-performance computing applications. Sweep3D, which simulates a single group time-independent discrete ordinates (Sn) neutron transport deterministically on 3D Cartesian geometry space, represents the key part of a real ASCI application. The wavefront process for parallel computation in Sweep3D limits the concurrent threads on the GPU. In this paper, we present multi-dimensional optimization methods for Sweep3D, which can be efficiently implemented on the finegrained parallel architecture of the GPU. Our results show that the overall performance of Sweep3D on the CPU-GPU hybrid platform can be improved up to 4.38 times as compared to the CPU-based implementation.

      • KCI등재후보
      • KCI등재

        Additive-assisted preferential crystallization of racemic component: A case of norvaline

        Jie Sun,Yaping Wang,Zhenguo Gao,Junbo Gong,Weiwei Tang 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-

        Herein, we report a successful resolution of L-norvaline, a racemic compound system, performed near theeutectic composition by coupling preferential crystallization with tailor-made additives. The structures ofenantiomer and racemate were characterized by PXRD, DSC, and the enantiomeric purity were measuredby Chiral HPLC. The preferential crystallization process was designed and established from binary meltingphase diagram and ternary solution phase diagram. The effects of supersaturation, solution enantiomercomposition, and seed quantity on the preferential crystallization process were investigated. However, the significant improvements of enantiomeric purity and product yield were demonstratedby additive-assisted preferential crystallization approach using tailor-made additives. These additivesbearing similar structure motifs to norvaline a highly selective binding to the racemate rather than enantiomerand remarkably suppress nucleation of DL-norvaline, the key factor determining the resultantenantiomer purity and separation efficiency. The underly inhibition principle was revealed due to thecentrosymmetric packing of the racemate while the polarity of enantiomer leads to only partial or slightcrystallization suppression. The interesting inhibition mode by tailor-made additives is also believed tobe applicable for other racemic crystallization systems. Our established additive-assisted preferentialcrystallization has showed great potential in the development of separation technology and resolutionof enantiomer from racemic compounds.

      • KCI등재

        LncRNA KIAA0087 suppresses the progression of osteosarcoma by mediating the SOCS1/JAK2/STAT3 signaling pathway

        Gong Haoli,Tao Ye,Xiao Sheng,Li Xin,Fang Ke,Wen Jie,He Pan,Zeng Ming 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Long noncoding RNAs (lncRNAs), widely expressed in mammalian cells, play pivotal roles in osteosarcoma (OS) progression. Nevertheless, the detailed molecular mechanisms of lncRNA KIAA0087 in OS remain obscure. Here, the roles of KIAA0087 in OS tumorigenesis were investigated. KIAA0087 and miR-411-3p levels were detected by RT-qPCR. Malignant properties were assessed by CCK-8, colony formation, flow cytometry, wound healing, and transwell assays. SOCS1, EMT, and JAK2/STAT3 pathway-related protein levels were measured by western blotting. Direct binding between miR-411-3p and KIAA0087/SOCS1 was validated by a dual-luciferase reporter, RIP, and FISH assays. In vivo growth and lung metastasis were evaluated in nude mice. The expression levels of SOCS1, Ki-67, E-cadherin, and N-cadherin in tumor tissues were measured by immunohistochemical staining. Downregulation of KIAA0087 and SOCS1 and upregulation of miR-411-3p were found in OS tissues and cells. Low expression of KIAA0087 was associated with a poor survival rate. Forced expression of KIAA0087 or miR-411-3p inhibition repressed the growth, migration, invasion, EMT, and activation of the JAK2/STAT3 pathway and triggered apoptosis of OS cells. However, the opposite results were found with KIAA0087 knockdown or miR-411-3p overexpression. Mechanistic experiments indicated that KIAA0087 enhanced SOCS1 expression to inactivate the JAK2/STAT3 pathway by sponging miR-411-3p. Rescue experiments revealed that the antitumor effects of KIAA0087 overexpression or miR-411-3p suppression were counteracted by miR-411-3p mimics or SOCS1 inhibition, respectively. Finally, in vivo tumor growth and lung metastasis were inhibited in KIAA0087-overexpressing or miR-411-3p-inhibited OS cells. In summary, the downregulation of KIAA0087 promotes the growth, metastasis, and EMT of OS by targeting the miR-411-3p-mediated SOCS1/JAK2/STAT3 pathway.

      • KCI등재

        중국 소비자의 미리 포장된 식사 구매 의도에 대한 이론적 기반 및 실증적 검증: 소비자 혁신성 관점에서 확장된 TPB 모델

        Hao-Jie Jiang,Chi Gong,Shuai Jiang 사회혁신기업연구원 2024 혁신기업연구 Vol.9 No.1

        COVID-19 팬데믹의 영향으로 중국의 미리 포장된 식사 산업이 빠른 성장 단계에 진입하여 소비자들로부터 점점 더 많은 호감을 얻고 있습니다. 이 연구는 중국 소비자들이 미리 포장된 식사를 구매하는 데 영향을 미치는 요인을 탐색하는 것을 목표로 합니다. 우리는 계획된 행동 이론(TPB)과 소비자 혁신성을 사용하여 구조방정식 모델을 구축했습니다. 이 정량적 연구는 비확률 샘플링 온라인 설문조사를 통해 293개의 유효 데이터 포인트를 수집하고 SPSS 27.0 및 AMOS 26.0을 사용하여 모델 검증을 수행했습니다. 결과는 소비자의 도구적 및 정서적 태도가 구매 의도에 중요하게 긍정적인 영향을 미친다는 것을 보여줍니다. 서술적 규범도 구매 의도에 중요한 긍정적인 영향을 미칩니다, 반면 지시적 규범은 중요한 영향을 보이지 않습니다. 소비자의 자기 통제력과 외부 조건은 모두 구매 의도와 행동에 중요한 긍정적인 영향을 미칩니다. 구매 의도는 구매 행동에 중요한 영향을 미치며 자기 통제력과 외부 조건에서의 매개 효과를 가집니다. 소비자 혁신성은 구매 의도와 행동 사이에서 중요한 조절 역할을 합니다. 제품 디자인과 홍보를 강화하기 위해 소비자들에게 매력을 높이는 것이 필수적입니다. 추가 연구를 위한 제안이 제시됩니다. Owing to the impact of the COVID-19 pandemic, the pre-made food industry in China has entered a rapid growth phase, gaining increasing favor from consumers. This study aims to explore the factors influencing Chinese consumers' purchase of pre-made food. We employed the Theory of Planned Behavior (TPB) and consumer innovativeness to construct a structural equation model. This quantitative study gathered 293 valid data points through non-probability sampling online surveys and employed SPSS 27.0 and AMOS 26.0 for model validation. Results reveal that consumers' instrumental and affective attitudes significantly positively influence purchase intention. Descriptive norms also exert a significant positive impact on purchase intention, while injunctive norms do not show a significant effect. Consumers' self-control and external conditions both have significant positive influences on purchase intention and behavior. Purchase intention significantly affects purchase behavior and mediates effects in self-control and external conditions. Consumer innovativeness plays a significant moderating role between purchase intention and behavior. To enhance product design and promotion, it is imperative to increase attractiveness to consumers. Suggestions for further research are presented.

      • KCI등재

        Cerium-doped carbon quantum dots trigger mung bean seeds to help mitigate salt stress by increasing the degree of stomata opening

        Dong Zihao,Gong Yan,Zhao Jie 한국탄소학회 2022 Carbon Letters Vol.32 No.7

        Since soil salinization imposes various adverse effects on plants, research on how to relieve salt stress from plants is extremely urgent. We synthesized a new type of cerium-doped carbon quantum dots by a hydrothermal synthesis method. Characterization shows that the carbon quantum dots have a small and uniform particle size, high stability, high water solubility and biocompatibility. Mung bean seeds were soaked in CDs:Ce solutions under a concentration gradient (0.25, 0.5, 1, 2, 3 mg/mL) and germinated under salt stress (150 mM NaCl). Compared with salt stress, the addition of CDs solutions effectively enhanced the ability of plants to relieve salt stress. The relieving effect on mung bean plants was the most significant after treatment with 2 mg/mL CDs:Ce, and the main root length, plant height and leaf length in comparison with the case of salt stress increased by 83%, 80%, and 60%, respectively. Chlorophyll content, peroxidase activity, superoxide dismutase activity and catalase activity, total protein content increased by 90%, 77%, 76%, 77% and 76%, respectively, malondialdehyde and proline The content decreased by 83% and 77%. Inductively coupled plasma mass spectroscopy proved mung bean plants absorbed CDs:Ce, but the absorption of NaCl decreased by 21.8%. Fluorescence imaging showed CDs:Ce was absorbed by roots, and transferred from the vascular system and apoplastic pathways to stems and leaf veins, and mainly aggregated in intercellular gaps, the vascular system, leaf veins, cilia and stomata. Stereomicroscopy showed that CDs:Ce induction increased the stomatal opening by 15.7%, and improved metabolic efficiency and NaCl excretion from the plants. Hence, CDs:Ce shows great potential in protecting crops from abiotic stress.

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