간질 환자의 불안과 우울에 관한 연구

변재영,장환일,신재정 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.6

The authors attempted to evaluate the severity of anxiety and depression in 36 epileptic patients who were out-patients at the department of neuropsychiatry of Kyung Hee University Hospital and Seoul National Mental Hospital in January through March, 1988 General Health questionnaire(GHQ), Zung’s Self-Rating Anxiety Scale(SAS) and Beck Depression Inventory(BDI) were administered to control and study group, and the scores of each checklist were compared in relation with the duration of epilepsy. The summary of the results were as follows: 1) The mean scores of GHQ were 10.67±4.92 in the epileptic patients and 6.71±2.22 in the control subjects. There was significant difference in the GHQ scores between the epileptic patients and the control subjects.The authors attempted to evaluate the severity of anxiety and depression in 36 epileptic patients who were out-patients at the department of neuropsychiatry of Kyung Hee University Hospital and Seoul National Mental Hospital in January through March, 1988 General Health questionnaire(GHQ),Zung’s Self-Rating Anxiety Scale(SAS) and Beck Depression Inventory(BDI) were administered to control and study group, and the scores of each checklist were compared in relation with the duration of ephilepsy. The summarry of the results were as follows: 1) The mean scores of GHQ were 10.67±4.92 in the epileptic patients and 6.71±2.22 in the control subjects. There was significant difference in the GHQ scores between the epileptic patients and the control subjects. 2) The mean scores of SAS were 36.67±9.96 in the epileptic patients and 28.33±6.41 in the control subjects. The difference in the SAS scores was significant between the epileptic patients and the control subjects. 3) The mean scores of BDI were 17.94±10.47 in the epileptic patients and 10.12±6.69 in the control subjects. The difference was significant. 4) The scores of 3 factors of BDI;“somatization”, Kunsatisfaction of interpersonal relationship” and“self-reproach”were significantly higher in the epileptic patients than in the control subjects. 5) The scores of GHQ, SAS and BDI were significantly lowered in epileptic patients with longer duration of illness, compared to those with shorter duration.

무용수의 운동중 호흡ㆍ 순환계 반응의 비교

변재경,주기찬,백왕일 韓國舞踊敎育學會 2000 韓國舞踊敎育學會誌 Vol.11 No.1

The purpose of this study was to compare the difference of cardiorespiratoy responses to exercise among three tapes of dancers, and to verify their cardiorespiratory charcteristics due to specificity of dance buck as the pattern of limb movement, velocity of motion and so forth The subject of this study were 44 female collegiate students and comprised of each 11 Korean dancers, modern dancers, ballet dancers, and untrained students. The dependent variables were minute ventilation respiratory frequency, tidal volume, exercise duration, oxygen uptake, heart rate, respiratory exchange ratio, O2 purse, and anaerobic threshold not only at 3minutes, 6minutes and 9minutes during graded exorcise test but also maximum level. With above experimental precess, the results were gained as follows: First, the minute ventilation of the ballet group progressively increased with the increase of workload of treadmill at 3minutes,6minutes, 9minutes and maximum level. That of the control group was significantly high in comparison with that of the ballet group at 3minutes, 6minutes and 9minutes, but there was no significant differences at maximum level. Second, the respiratory frequency, tidal volume and O2 purse progressively increased in all groups with the increase of workload at 3minutes, 6minutes, 9minutes and maximum level, but there was no statistically significant differences. Third, as for the mean exorcise duration of all the group, the ballet dancers showed 10min. 27sec, the Korean dancers 10min, 15sec, the modern dancers 9min-56sec and the control group 9min. 36sec. The control group was significantly high in comparison with the ballet group. Fourth, the oxygen uptake(VO2) progressively increased with the increase of workload in all the dancers' groups. At 6 minutes, the control group was significantly high in ccmparison with the modern dancers. At 9 minutes, the ballet dancers was signiflcantly high in comparison with the modern dancers. At maximum level, the ballet dancers was signiscantly high in comparison with the rest three groups. Fifth, the respiratory exchange ratio progressively increased with the increase of workload in all groups. At 3 minutes, the modern dancer was significantly high in comparison with the control group, while at 9 minutes, the control group was significantly high in comparison with the Korean dancers. Sixth, the heart rate (HR) increased progressively in all groups with the increase of workload. At 9 minutes, the HR of the control group was significantly high in comparison with that of the rest three groups. Seventh, as for anaerobic threshold according to % VO2 max, the ballet dancers was 67.24 6.74, the Korean dancers 62.30 4.50, the modern dancers 67.32 8.30, and the control group 63.30 4.50. There was no significant differences in anaerobic threshold of three types of dancers. With the above results, the groups of ballet dancers and modern dancers were significantly high in oxygen uptake, heart rate and exercise duration in comparison with other groups because the groups of ballet dancers and modem dancers do a lot of physical training. Moreover, the group of ballet dancers was the highest in cardiorespiratory function of all the other groups.

긴장증의 임상적 특성에 대한 고찰

송지영,윤도준,변재영,장환일 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.3

26 cases(9 males and 17 females) with catatonia features on admission were analyzed in terms of its clinical characteristics. The results obtained were as follows : 1) In the diagnostic distribution, more than a half of the cases were schizophrenic disorders(57.5%) and the others were major depressions(26.9%) and schizophreniform disorders(15.4%). 2) The catatonia signs were nonspecific and evenly distributed among a variety of clinical diagnostic entities. But the signs of negativism, mutism, and posturing appeared frequently in all cases. 3) Acute onset was prevalent(65.4%), ECT was more frequently applied(61.5%) and treatment response was better(70.9%) in the catatonia group than non-catatonia. Although the definition of catatonia is not clear yet, above results support the opinions of previous studies that catatonia should be understood as a heterogenous symptom complex. And not only schizophrenia but also affective disorder are associated with catatonia features. This suggests that we have to re-evaluate the concept of Kahlbaum's old description.

Reduction of Visceral and Body Fats in Mice by Supplementation of Conjugated Linoleic Acid with γ-Oryzano

Jae Il Byeon,Yeong Lae Ha,Tae Woo Oh,Seon Min Lee,Wook Jin Jang,Md. Abdur Rakib,Young Suk Kim,Cherl Woo Park,Jeong Ok Kim 한국응용생명화학회 2008 Applied Biological Chemistry (Appl Biol Chem) Vol.51 No.5

[P8-293] Differential Bactericidal Effect of Conjugated Linoleic Acid Against Gram-Positive and Gram-Negative Food-Borne Bacteria

Jae Il Byeon,Han Suep Song,Tae Woo Oh,Young Suk Kim,Wook Jin Jang,Byeong Dae Choi,Hong Chul Kim,Jeong OK Kim,Ki Hwan Shim,Yeong Lae Ha 한국식품영양과학회 2009 한국식품영양과학회 학술대회발표집 Vol.2009 No.11

Reduction of Visceral and Body Fats in Mice by Supplementation of Conjugated Linoleic Acid with γ-Oryzanol

Jae Il Byeon(변재일),Tae Woo Ohr(오태우),Young Suk Kim(김영숙),Yeon Gyu Moon(문연규),Cherl Woo Park(박철우),Jeong Ok Kim(김정옥),Yeong Lae Ha(하영래) 한국생명과학회 2008 생명과학회지 Vol.18 No.9

Conjugated linoleic acid (CLA)와 γ-oryzanol (OZ) 혼합물의 mouse 체지방 및 복부지방 감소에 관한 연구를 하였다. Female ICR mice (10주 령)을 몸무게 차이가 없도록 Control (70 μl olive oil + 30 μl CLA), CLA-OZ 1 (70 μl olive oil + 30 μl CLA + 0.5 ㎎ OZ), CLA-OZ 2 (70 μl olive oil + 30 μl CLA + 1.0 ㎎ OZ), OZ (100 μl olive oil + 1.0 ㎎ OZ) 및 Olive oil (100 μl olive oil)로 구분하였다. 처리시료는 매일 4주간 경구투여 하였고 식이와 물은 자유롭게 먹게 하였다. 시료처리 4주 후에 mice의 몸무게를 달고 탈골법으로 sacrifice하여 전체몸무게, 복부지방 무게, 장기와 복부지방을 제거한 나머지 부분 무게 (empty carcass weight: ECW)를 측정하였다. CLA (control) 처리는 olive oil 처리에 비해 유의성 있게 몸무게, ECW, 복부지방 및 체지방을 감소시켜 CLA가 복부지방 및 체지방을 감소시킴을 알 수 있었다. CLA-OZ 1 처리는 OZ 처리에 비해서는 복부지방 및 체지방을 유의성 (p<0.05) 있게 감소시켰으나 CLA (control) 처리에 비해서는 유의성이 없었다. 또한 CLA-OZ 2 처리는 control 처리 및 OZ 처리에 비해 복부지방 및 체지방을 유의성 (p<0.05) 있게 감소시켰다. 이 결과는 CLA와 OZ를 혼합하여 처리한 mice에서 이들을 각각 단독으로 처리한 mice에서보다 복부지방 및 체지방이 많이 감소되어 OZ가 CLA의 지방감소 작용에 상승효과가 있음을 의미한다. The synergistic effect of conjugated linoleic acid (CLA) and γ-oryzanol (OZ) on the reduction of visceral and body fats was investigated in mice. Female ICR mice, 10 weeks of age, were acclimated for one week and then randomly divided into 5 treatment groups by body weights: Control (70 μl olive oil + 30 μ CLA), CLA-OZ 1 (70 μl olive oil + 30 μl CLA + OZ 0.5 ㎎), CLA-OZ 2 (70 μl olive oil + 30 μl CLA + OZ 1.0 ㎎), OZ (100 μl olive oil + OZ 1.0 ㎎), and Olive oil (100 μl olive oil). Samples were daily intubated, p.o., for 4 weeks. Food and water were ad libitum. Four weeks later, mice were sacrificed by neck dislocation, followed by measuring whole body weight, empty carcass weight (ECW), which is weight without organs and visceral fats, visceral fats, body fats and protein content. Mice treated with CLA (control) sample maintained significantly, p<0.05, lower whole body weight, ECW, visceral and body fats, relative to mice treated with olive oil sample, indicating that CLA reduces the visceral and body fats. The CLA-OZ 1 treatment significantly reduced, p<0.05, visceral and body fats as compared to OZ treatment, but not significantly different from control treatment. Meanwhile, CLA-OZ 2-treated mice maintained significantly, p<0.05, lower visceral and body fats than control and OZ-treated mice. Protein contents in mice were not affected by any other treatments. These results suggest that OZ enhanced the reduction of visceral and body fats in mice by CLA.

Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.

Cheon, Jae Hee,Kim, Jae Hak,Kim, Bo Young,Kim, Seung Won,Hong, Sung Yi,Eun, Chang Soo,Hong, Seong Soo,Byeon, Jeong-Sik,Kim, Tae Il,Han, Dong Soo,Yang, Suk-Kyun,Lee, Kyoung Ryul,Kim, Won Ho G. Thieme 2009 Hepato-gastroenterology Vol.56 No.90

<P>BACKGROUND/AIMS: Adverse reactions to thiopurines may be predisposed by thiopurine methyltransferase (TPMT) or inosine triphosphate pyrophosphatase (ITPA) gene mutations. METHODOLOGY: We examined the frequencies of TPMT and ITPA gene polymorphisms in 812 Korean patients with inflammatory bowel diseases using denaturing high performance liquid chromatography and direct sequencing. Results: The allele frequencies of TPMT*2, TPMT*3A, TPMT*3B, and TPMT*3C were 0, 0, 0, and 0.010 (17/1624), respectively. For the ITPA polymorphism, 173 subjects were heterozygous and 5 were homozygous for the 94C>A missense mutation (allele frequency of A, 0.113). Moreover, the 87T>C, IVS2+21A>C, and IVS2+53C>T polymorphisms were found in one patient each (1/1624), respectively. Of these, 87T>C and IVS2+53C>T were novel single nucleotide polymorphisms of the ITPA gene whose clinical significance should be further evaluated. CONCLUSIONS: Our data describe TPMT and ITPA gene mutation patterns among Koreans and provide a basis for screening studies to identify patients at high risk for myelotoxicity from thiopurine drugs.</P>

무용수의 운동중 호흡,순환제 반응의 비교

변재경 ( Jae Kyung Byeon ),주기찬 ( Kee Chan Joo ),백왕일 ( Wang Il Baek ) 한국무용교육학회 2000 韓國舞踊敎育學會誌 Vol.11 No.1

남자 단거리 롤러 스피드 스케이팅 선수들의 경기기록과 체력 변인 간의 상관분석

변재경(Byeon Jae-Kyung),이성일(Lee Sung-Il),박순희(Park Sun-Hee),정수정(Jeong Soo-Jeong),민수경(Min Su-Kyung) 한국코칭능력개발원 2012 코칭능력개발지 Vol.14 No.1

규제위반에 대한 행정부의 금전적 제재: 공정거래법상 과징금 수준의 결정요인에 관한 실증분석

금일중 ( Il Joong Kim ),금진호 ( Jin Ho Kim ),변재욱 ( Jae Wook Byeon ) 서울대학교 법학연구소 2010 서울대학교 法學 Vol.51 No.1

This article probes into the legal and economic grounds underlying the administrative monetary penalty (i.e., surcharge), the use of which has been growing very rapidly as a monetary penalty against the violation of numerous areas of public policy in Korea. Subsequently, it empirically examines the major determinants of the surcharge amounts actually imposed. Although the surcharge is stipulated in more than 100 substantive laws, we focus on the Korean Fair Trade Law, the reason being that its imposition, both in frequency and scale, has been overwhelming especially in the area of antitrust and unfair trades. We use surcharge cases decided by the Fair Trade Commission. According to the estimation results, most of the proxies included in three groups (ECO, LAW, CONTROL) experimentally designed for this article command high explanatory power, statistically explaining around 80% of the dependent variable. From the economic perspective, the essence for warranting the optimal surcharge system is to reflect accurately the `harm level` caused by a violator and the `detection probability` of violation. Our empirical investigation reveals that the former has been adequately reflected. In addition, the latter seems to have been taken into account, too, although it is unclear to how much extent the result has actually been the outcome of the Commission`s intentional efforts. Finally, this article offers critical policy implications and future research agenda derived from the overall empirical analyses in order to construct a more efficient system of surcharge in longer terms.