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      • KCI등재

        전기 방열기가 국화재배온실의 난방에 미치는 영향

        서원명 ( Won Myung Suh ),임재운 ( Jae Woon Leem ),김영주 ( Young Ju Kim ),민영봉 ( Young Bong Min ),김현태 ( Hyeon Tae Kim ),허무룡 ( Moo Ryong Huh ),윤용철 ( Yong Cheol Yoon ) 경상대학교 농업생명과학연구원(구 경상대학교 농업자원이용연구소) 2010 농업생명과학연구 Vol.44 No.4

        경상대학교 교내에 설치되어 있는 1-2W형 온실을 대상으로 전기 방열기를 이용하여 국화 재배온실의 난방효과를 검토한 결과는 다음과 같다. 실험기간동안 최고, 평균 및 최저 외기온은 각각 -3.8~21.3℃, -5.2~16.1℃ 및 -12.5~14.4℃ 정도의 범위로 나타났으며, 온실 내외의 평균상대습도 각각 43.5~98.6% 및 35.2~100%로 나타났다. 12월 중순부터 2월 상순까지 최저 외기온은 대략 -5.0~-10.0℃ 전후로 나타나 진주기상대의 최근 자료와 비교하면 상대적으로 최저기온이 낮게 나타나는 경향이 있었다. 야간의 경우, 방열기 직하부의 엽온이 방열기 중간 지점에서 측정한 엽온 보다 크게 2~3℃정도 높게 나타나거나 또는 미미하지만 약간 높게 나타나는 경향이 있었다. 근권부의 경우, 직하부나 중간 지점에서의 온도 차이는 거의 없는 것으로 나타났고, 근권부의 최고온도와 기타 최고 온도의 발생 시점을 보면, 약 2시간정도의 지체현상이 있음을 알 수 있었다. 그리고 실험기간동안 난방에 소요된 총 소비전력량, 공급에너지 및 총 난방비는 각각 2,800kWh, 2,408,000kcal 및 112,000won 정도였다. 화석연료인 경유로 난방할 경우, 총 난방비는 224,500won 정도였다. 방열기를 이용하여 난방할 경우, 난방비를 약 50% 정도 줄일 수 있을 것으로 판단되었다. An analysis in heating effects of an electric radiator located in a 1-2W type chrysanthemum (3 cultivars) cultivation greenhouse installed in Gyeongsang National University drew the following conclusions. During the experiment period, the highest, average, and the lowest outside temperatures were in the ranges of -3.8~21.3℃, -5.2~16.1℃ and -12.5~14.4℃, respectively, and the average relative humidity inside and outside the greenhouses were in the ranges of 43.5~98.6% and 35.2~100%, respectively. From mid-December to early February, the lowest outside temperature was recorded as approximately -5.0~-10.0℃, which showed that it tended to be relatively lower than the temperatures recorded at the Jinju Meteorological Observatory. During the night, the leaf temperature measured directly under the radiator tended to be higher by 2~3℃ than that those at the middle point of the radiator, or higher by anegligible amount. In the case of root zone temperature, it was found that there was almost no difference between temperatures of the part directly under and the middle point, and the time when the highest temperature of root zone and other highest temperatures took place showed that there was about a 2-hour delay phenomenon. The total electricity consumption, energy supply and total heating cost during the experiment period were 2,800 kWh, 2,408,000 kcal and 112,000 won, respectively. When diesel, a kind of fossil fuel, was used as heating oil, the total heating cost was around 224,500 won. It was estimated that the total heating cost could be reduced by around 50% if a radiator was used.

      • KCI등재SCISCIE

        Identification and molecular characterization of PERV Gamma1 long terminal repeats

        Huh, Jae-Won,Kim, Dae-Soo,Ha, Hong-Seok,Ahn, Kung,Chang, Kyu-Tae,Cho, Byung-Wook,Kim, Heui-Soo Korean Society for Molecular Biology 2009 Molecules and cells Vol.27 No.1

        Porcine endogenous retroviruses (PERVs) gamma1 in the pig genome have the potential to act as harmful factors in xenotransplantation (pig-to-human). Long terminal repeats (LTRs) are known to be strong promoter elements that could control the transcription activity of PERV elements and the adjacent functional genes. To investigate the transcribed PERV gamma1 LTR elements in pig tissues, bioin-formatic and experimental approaches were conducted. Using RT-PCR amplification and sequencing approaches, 69 different transcribed LTR elements were identified. And 69 LTR elements could be divided into six groups (15 subgroups) by internal variation including tandem repeated sequences, insertion and deletion (INDEL). Remarkably, all internal variations were indentified in U3 region of LTR elements. Taken together, the identification and characterization of various PERV LTR transcripts allow us to extend our knowledge of PERV and its transcriptional study.

      • A Study on the Application of a Superconducting Fault Current Limiter for Energy Storage Protection in a Power Distribution System

        Won-Sik Moon,Jong-Nam Won,Jae-Sun Huh,Jae-Chul Kim IEEE 2013 IEEE transactions on applied superconductivity Vol.23 No.3

        <P>This paper presents the application of a superconducting fault current limiter to energy storage for protection in a power distribution system. An energy storage system is increasingly being used to help renewable energy resources integrate into the grid. It is important to keep an energy storage system interconnected with the grid without interruption and to supply electrical power to the grid. The main objective of this paper is to introduce a superconducting fault current limiter to keep the energy storage system from disconnecting from the grid when ground faults occur. Its effect is analyzed using transient simulation software.</P>

      • SCOPUSKCI등재

        Recent trends in intensity-modulated radiation therapy use in Korea

        Huh, Seung Jae,Park, Won,Choi, Do Ho The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.4

        Purpose: We aimed to analyze the trend in intensity-modulated radiation therapy (IMRT) use in Korea from 2011 to 2018. Materials and Methods: We collected data from the Health and Insurance Review and Assessment Service (HIRA) big data based on the National Health Insurance Service claims and reimbursements records using primary treatment planning codes (HD 041) for IMRT from 2011 to 2018. We analyzed the changing patterns in clinical application to specific tumor sites and regional differences in IMRT utilization. Results: The use of IMRT has exhibited an 18-fold steep rise from 1,921 patients in 2011 to 34,759 in 2018. With regard to IMRT in 2018, 70% of patients (24,248/34,759) were treated in metropolitan areas (Seoul, Incheon, and Gyeonggi Province). IMRT was most commonly used to treat breast, lung, and prostate cancers in 2018. Among these, the use of IMRT for breast cancer shows the most remarkable increase from 2016 when the National Health Insurance began to cover IMRT for all solid tumors. Conclusion: The use of IMRT is steadily increasing to treat cancer and is concentrated in metropolitan areas.

      • KCI등재
      • KCI등재

        Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases: A Single Center Experience

        Won Kyung Kwon,SooIn Choi,Hee-Jin Kim,Hee-Jae Huh,Ji-Man Kang,김예진,유건희,Kangmo Ahn,Hye-Kyung Cho,Kyong Ran Peck,장자현,Chang-Seok Ki,Eun-Suk Kang 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.2

        Purpose: While there is an urgent need for diagnosis and therapeutic intervention in patients with primary immunodeficiency diseases (PIDs), current genetic tests have drawbacks. We retrospectively reviewed the usefulness of flow cytometry (FCM) as a quick tool for immunophenotyping and functional assays in patients suspected to have PIDs at a single tertiary care institute. Methods: Between January 2001 and June 2018, patients suspected of having PIDs were subjected to FCM tests, including lymphocyte subset analysis, detection of surface- or intracellular-target proteins, and functional analysis of immune cells, at Samsung Medical Center, Seoul, Korea. The genetic diagnosis was performed using Sanger or diagnostic exome sequencing. Results: Of 60 patients diagnosed with definite or probable PID according to the European Society of Immune Deficiencies criteria, 24 patients were provided with useful information about immunological dysfunction after initial FCM testing. In 10 patients, the PID diagnosis was based on abnormal findings in FCM testing without genetic tests. The FCM findings provided strong evidence for the diagnosis of severe combined immunodeficiency (n = 6), X-linked chronic granulomatous diseases (CGD) (n = 6), leukocyte adhesion deficiency type 1 (n = 3), X-linked agammaglobulinemia (n = 11), autoimmune lymphoproliferative syndrome-FASLG (n = 1), and familial hemophagocytic lymphohistiocytosis type 2 (n = 1), and probable evidence for autosomal recessive-CGD (n = 2), autosomal dominant-hyper-immunoglobulin E (IgE)-syndrome (n = 1), and STAT1 gain-of-function mutation (n = 1). In PIDs derived from PIK3CD (n = 2), LRBA (n = 2), and CTLA4 mutations (n = 3), the FCM test provided useful evidence of immune abnormalities and a tool for treatment monitoring. Conclusions: The initial application of FCM, particularly with known protein targets on immune cells, would facilitate the timely diagnosis of PIDs and thus would support clinical decisions and improve the clinical outcome.

      • Four different ways of alternative transcripts generation mechanism in <i>ADRA1A</i> gene

        Huh, Jae-Won,Kim, Young-Hyun,Lee, Sang-Rae,Kim, Dae-Soo,Park, Sang-Je,Kim, Hyoungwoo,Kim, Ji-Su,Song, Bong-Seok,Kim, Heui-Soo,Chang, Kyu-Tae The Genetics Society of Japan 2010 Genes & genetic systems Vol.85 No.1

        <P>The <I>ADRA1A</I> (Alpha-1-adrenergic receptor) gene is one of the members of G protein-coupled receptor superfamily. Alternative splicing of this gene was known to generate four transcript variants which code four isoforms with various C-terminal regions. In this study, we conducted expression analysis and evolutionary characterization of alternative transcripts of the <I>ADRA1A</I> gene. In total, 10 alternative transcripts were identified using experimental approaches and <I>in silico</I> analysis. Among them, 6 alternative transcripts (T1, T2, T3, T4, T4-1, and T8) were validated by RT-PCR approaches and sequencing procedures. From the alternative splicing analysis, it could be assumed that there were three different alternative transcripts generation mechanisms and unknown mechanism. First one is the integration event of three different TEs (<I>AluSc</I>, L1MC5, and MIR3) as seen on the last exons of T3, T4, T4-1, T5, T6, and T7 transcripts. The second mechanism is a differential promoter usage on T8. The third one is a substitution event of the 3’ splicing site during the primate evolution on T3. The last one is an unknown mechanism which was identified in the T4-1 transcript. Therefore, alternative transcripts of human <I>ADRA1A</I> gene occurred by four different ways, such as integration of TEs, differential promoter usage, substitution of splicing sites, and unknown mechanism.</P>

      • SCOPUSKCI등재

        Role of AMP-Activated Protein Kinase (AMPK) in Smoking-Induced Lung Inflammation and Emphysema

        ( Jae Seung Lee ),( Sun Joo Park ),( You Sook Cho ),( Jin Won Huh ),( Yeon Mok Oh ),( Sang Do Lee ) 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.1

        Background: AMP-activated protein kinase (AMPK) not only functions as an intracellular energy sensor and regulator, but is also a general sensor of oxidative stress. Furthermore, there is recent evidence that it participates in limiting acute inflammatory reactions, apoptosis and cellular senescence. Thus, it may oppose the development of chronic obstructive pulmonary disease. Methods: To investigate the role of AMPK in cigarette smoke-induced lung inflammation and emphysema we first compared cigarette smoking and polyinosinic-polycytidylic acid [poly(I:C)]-induced lung inflammation and emphysema in AMPKa1-deficient (AMPKa1-HT) mice and wild-type mice of the same genetic background. We then investigated the role of AMPK in the induction of interleukin-8 (IL-8) by cigarette smoke extract (CSE) in A549 cells. Results: Cigarette smoking and poly(I:C)-induced lung inflammation and emphysema were elevated in AMPKa1-HT compared to wild-type mice. CSE increased AMPK activation in a CSE concentration- and time-dependent manner. 5-Aminoimidazole-4-carboxamide-1-b-4-ribofuranoside (AICAR), an AMPK activator, decreased CSE-induced IL-8 production while Compound C, an AMPK inhibitor, increased it, as did pretreatment with an AMPKa1-specific small interfering RNA. Conclusion: AMPKa1-deficient mice have increased susceptibility to lung inflammation and emphysema when exposed to cigarette smoke, and AMPK appears to reduce lung inflammation and emphysema by lowering IL-8 production.

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