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      • KCI등재후보

        가브리엘라 미스트랄이 시적으로 개작한 네 가지 고전 동화

        안드레아카살스힐 ( Anerea Casals Hill ),정현주(번역) 방정환연구소 2020 방정환연구 Vol.3 No.-

        안드레아 카살스 힐(Andrea Casals Hill)은 칠레 작가가 시적으로 개작한 이야기, 『백설공주』(Blanca Nieve), 『빨간 모자』(Caperucita Roja), 『신데렐라』(Cenininca), 『잠자는 숲속의 미녀』(La Bella Durmiente)를 소개하고 분석한다. 이 책들은 최근 그림책으로 재출간되어 호평을 받고 있다. 가브리엘라 미스트랄(Gabriela Mistral)은 라틴 아메리카의 작가로는 처음으로 노벨 문학상을 받았다. 카살스 힐에 따르면, 미스트랄이 시적으로 개작한 『백설공주』, 『빨간 모자』, 『신데렐라』, 『잠자는 숲속의 미녀』는 보이지 않고, 버려지고, 학대 받는 젊은 여성 청자의 자율권(empowerment)을 가능하게 하려는 미스트랄의 윤리적인 헌신을 반영한다. Andrea Casals Hill presents and analyzes the acclaimed Chilean author’s poetic retellings of Snow White, Little Red Riding Hood, Cinderella, and Sleeping Beauty, which have been recently republished as illustrated books. Gabriela Mistral was the first Latin American author to receive a Nobel Prize in Literature. Casals Hill asserts that her poetic retellings of Caperucita Roja, Blanca Nieve, Cenicienta, and La Bella Durmiente reflect Mistral’s ethical commitment to enable the empowerment of her invisible, abandoned, and abused young female audience.

      • SCOPUSKCI등재

        반복유산을 경험한 환자에서 임신중 태반항원과 동종항원에 노출된 모체 림프구면역반응은 언제부터 소실되나?

        최범채,Choi, Bum-Chae,Hill, Joseph A. 대한생식의학회 1998 Clinical and Experimental Reproductive Medicine Vol.25 No.2

        The maintenance of a viable pregnancy has long been viewed as an immunological paradox. The deveolping embryo and trophoblast are immunologically foreign to the maternal immune system due to their maternally inherited genes products and tissue-specific differentiation antigens (Hill & Anderson, 1988). Therefore, speculation has arisen that spontaneous abortion may be caused by impaired maternal immune tolerance to the semiallogenic conceptus (Hill, 1990). Loss of recall antigen has been reported in immunosuppressed transplant recipients and is associated with graft survival (Muluk et al., 1991; Schulik et al., 1994). Progesterone $(10^{-5}M)$ has immunosuppressive capabilities (Szekeres-Bartho et al., 1985). Previous study showed that fertile women, but not women with unexplained recurrent abortion (URA), lose their immune response to recall antigens when pregnant (Bermas & Hill, 1997). Therefore, we hypothesized that immunosuppressive doses of progesterone may affect proliferative response of lymphocytes to trophoblast antigen and alloantigen. Proliferative responses using $^3H$-thymidine ($^3H$-TdR) incorporation of peripheral blood mononuclear cells (PBMCs) to the irradiated allogeneic periperal blood mononuclear cells as alloantigen, trophoblast extract and Flu as recall antigen, and PHA as mitogen were serially checked in 9 women who had experienced unexplained recurrent miscarriage. Progesterone vaginal suppositories (100mg b.i.d; Utrogestan, Organon) beginning 3 days after ovulation were given to 9 women with unexplained RSA who had prior evidence of Th1 immunity to trophoblast. We checked proliferation responses to conception cycle before and after progesterone supplementation once a week through the first 7 weeks of pregnancy. All patients of alloantigen and PHA had a positive proliferation response that occmed in the baseline phase. But 4 out of 9 patients (44.4%) of trophoblast antigen and Flu antigen had a positive proliferative response. The suppression of proliferation response to each antigen were started after proliferative phase and during pregnancy cycles. Our data demonstrated that since in vivo progesterone treated PBMCs suppressed more T-lymphocyte activation and $^3H$-TdR incorporation compare to PBMCs, which are not influenced by progesterone. This data suggested that it might be influenced by immunosuppressive effect of progesterone. In conclusion, progesterone may play an important immunological role in regulating local immune response in the fetal-placental unit. Furthermore, in the 9 women given progesterone during a conception cycle, Only two (22%) repeat pregnancy losses occured in these 9 women despite loss of antigen responsiveness (one chemical pregnancy loss and one loss at 8 weeks of growth which was karyotyped as a Trisomy 4). These finding suggested that pregnancy loss due to fetal aneuploidy is not associated with immunological phenomena.

      • Colloidal polymers from inorganic nanoparticle monomers

        Hill, Lawrence J.,Pinna, Nicola,Char, Kookheon,Pyun, Jeffrey Elsevier 2015 Progress in polymer science Vol.40 No.-

        <P><B>Abstract</B></P> <P>The use of preformed inorganic nanoparticles as “colloidal monomers” has received recent attention for the formation of one-dimensional (1-D) mesostructures, or “colloidal polymers.” These colloidal monomers form linear assemblies through attractive, directional, interparticle interactions, which are similar to covalent or supramolecular interactions in classical polymer science. However, in contrast to the high degree of structural control available in the synthesis of classical molecular polymers, methods to control fundamental structural features such as chain length (DP), composition (copolymers), and architecture (linear, branched, etc.) are still being developed for NP-based colloidal polymer systems. We therefore review the colloidal polymerization of inorganic nanoparticle monomers by applying the conceptual framework provided by polymer science to categorize these novel systems. The descriptive nomenclature used for classical polymers is applied to NP assembly to define more explicitly the types of colloidal polymers formed in terms of DP, architecture, and composition (for binary NP assemblies). This review includes descriptions of inorganic nanoparticle types useful for the formation of colloidal polymers with examples chosen to demonstrate control over mesoscopic structure and composition. The various emergent optical, electrical and electrochemical properties from these materials are also reviewed and correlated with structural control achieved in various colloidal polymer systems.</P>

      • SCIESCOPUS

        Wild waterfowl migration and domestic duck density shape the epidemiology of highly pathogenic H5N8 influenza in the Republic of Korea

        Hill, Sarah C.,Lee, Youn-Jeong,Song, Byung-Min,Kang, Hyun-Mi,Lee, Eun-Kyoung,Hanna, Amanda,Gilbert, Marius,Brown, Ian H.,Pybus, Oliver G. Elsevier Science 2015 INFECTION GENETICS AND EVOLUTION Vol.34 No.-

        <▼1><P><B>Highlights</B></P><P>•<P>Phylogeographic analyses of H5N8, including 49 new sequences from South Korea.</P>•<P>H5N8 movement was mostly among areas dense in wild and domestic ducks.</P>•<P>New viral introductions to South Korea occurred at time of wild bird migration.</P>•<P>H5N8 epidemiology is shaped by wild waterfowl migration and domestic duck density.</P>•<P>H5N8 may have entered Europe at least twice, and Asia at least three times.</P></P></▼1><▼2><P>Highly pathogenic avian influenza (HPAI) viruses threaten human and animal health yet their emergence is poorly understood, partly because sampling of the HPAI Asian-origin H5N1 lineage immediately after its identification in 1996 was comparatively sparse. The discovery of a novel H5N8 virus in 2013 provides a new opportunity to investigate HPAI emergence in greater detail. Here we investigate the origin and transmission of H5N8 in the Republic of Korea, the second country to report the new strain. We reconstruct viral spread using phylogeographic methods and interpret the results in the context of ecological data on poultry density, overwintering wild bird numbers, and bird migration patterns. Our results indicate that wild waterfowl migration and domestic duck density were important to H5N8 epidemiology. Specifically, we infer that H5N8 entered the Republic of Korea via Jeonbuk province, then spread rapidly among western provinces where densities of overwintering waterfowl and domestic ducks are higher, yet rarely persisted in eastern regions. The common ancestor of H5N8 in the Republic of Korea was estimated to have arrived during the peak of inward migration of overwintering birds. Recent virus isolations likely represent re-introductions via bird migration from an as-yet unsampled reservoir. Based on the limited data from outside the Republic of Korea, our data suggest that H5N8 may have entered Europe at least twice, and Asia at least three times from this reservoir, most likely carried by wild migrating birds.</P></▼2>

      • KCI등재

        Myoclonic status epilepticus after severe hyperthermia in a patient with coronavirus disease 2019

        Hill Katherine A,Peters John J,Schaefer Sara M 대한중환자의학회 2023 Acute and Critical Care Vol.38 No.4

        Myoclonic status epilepticus (MSE) is a sign of severe neurologic injury in cardiac arrest patients. To our knowledge, MSE has not been described as a result of prolonged hyperpyrexia. A 56-yearold man with coronavirus disease 2019 presented with acute respiratory distress syndrome, septic/hypovolemic shock, and presumed community-acquired pneumonia. Five days after presentation, he developed a sustained fever of 42.1°C that did not respond to acetaminophen or ice water gastric lavage. After several hours, he was placed on surface cooling. Three hours after fever resolution, new multifocal myoclonus was noted in the patient’s arms and trunk. Electroencephalography showed midline spikes consistent with MSE, which resolved with 40 mg/kg of levetiracetam. This case demonstrates that severe hyperthermia can cause cortical injury significant enough to trigger MSE and should be treated emergently using the most aggressive measures available. Providers should have a low threshold for electroencephalography in intubated patients with a recent history of hyperpyrexia.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        The Interaction of Cognitive Interference, Standing Surface, and Fatigue on Lower Extremity Muscle Activity

        Hill, Christopher M.,DeBusk, Hunter,Simpson, Jeffrey D.,Miller, Brandon L.,Knight, Adam C.,Garner, John C.,Wade, Chip,Chander, Harish Occupational Safety and Health Research Institute 2019 Safety and health at work Vol.10 No.3

        Background: Performing cognitive tasks and muscular fatigue have been shown to increase muscle activity of the lower extremity during quiet standing. A common intervention to reduce muscular fatigue is to provide a softer shoe-surface interface. However, little is known regarding how muscle activity is affected by softer shoe-surface interfaces during static standing. The purpose of this study was to assess lower extremity muscular activity during erect standing on three different standing surfaces, before and after an acute workload and during cognitive tasks. Methods: Surface electromyography was collected on ankle dorsiflexors and plantarflexors, and knee flexors and extensors of fifteen male participants. Dependent electromyography variables of mean, peak, root mean square, and cocontraction index were calculated and analyzed with a $2{\times}2{\times}3$ within-subject repeated measures analysis of variance. Results: Pre-workload muscle activity did not differ between surfaces and cognitive task conditions. However, greater muscle activity during post-workload balance assessment was found, specifically during the cognitive task. Cognitive task errors did not differ between surface and workload. Conclusions: The cognitive task after workload increased lower extremity muscular activity compared to quite standing, irrespective of the surface condition, suggesting an increased demand was placed on the postural control system as the result of both fatigue and cognitive task.

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