Intra-articular replacement of a ruptured cranial cruciate ligament using the Mini-TightRope in the dog: a preliminary study

Pinna, Stefania,Lanzi, Francesco,Tassani, Chiara,Mian, Giacomo The Korean Society of Veterinary Science 2020 Journal of Veterinary Science Vol.21 No.2

Background: The TightRope System is a device developed to provide extracapsular stabilization of the cranial cruciate ligament (CCL) rupture in canine stifles. I was then also employed for the extra-articular treatment of shoulder instability and for the intra-articular treatment of hip luxation in dogs and cats. Objectives: To evaluate the feasibility of the Mini-TightRope (mTR) System for the intraarticular treatment of CCL rupture in small breed dogs. Methods: A cadaveric canine model was used to record the steps of the surgical procedure. Five client owned dogs weighing from 8 to 10 kg and from 2 to 12 years of age were enrolled in the prospective study in which the mTR device was implanted in the stifle joint to replace the ruptured CCL. The dogs were graded using the Bologna Healing Stifle Injury Index (BHSII) and radiographic osteoarthritis (OA) scores. Results: The outcomes obtained at the time of the surgery (T0) and for the following 12 months (T12) showed an improvement in the functional parameters (BHSII from a median of 74.3 [range, 58.1-82.4] at T0 to 95.6 [range, 94.1-99.3] at T12]). The OA did not change in 3 dogs and increased by only 1 point in 2 dogs. Conclusions: In this preliminary study, the mTR was a successful and repeatable intraarticular surgical procedure for all dogs. Additional studies related to the clinical application of the technique in medium-large dogs should be encouraged.

The “benzyl alcohol route”: An elegant approach towards doped and multimetal oxide nanocrystals : Short review and ZnAl2O4 nanostructures by oriented attachment

Pinna, Nicola,Karmaoui, Mohamed,Willinger, Marc-Georg Springer-Verlag 2011 Journal of sol-gel science and technology Vol.57 No.3

Intra-articular replacement of a ruptured cranial cruciate ligament using the Mini-TightRope in the dog: a preliminary study

Stefania Pinna,Francesco Lanzi,Chiara Tassani,Giacomo Mian 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.5

Background: The TightRope System is a device developed to provide extracapsular stabilization of the cranial cruciate ligament (CCL) rupture in canine stifles. I was then also employed for the extra-articular treatment of shoulder instability and for the intra-articular treatment of hip luxation in dogs and cats. Objectives: To evaluate the feasibility of the Mini-TightRope (mTR) System for the intra-articular treatment of CCL rupture in small breed dogs. Methods: A cadaveric canine model was used to record the steps of the surgical procedure. Five client owned dogs weighing from 8 to 10 kg and from 2 to 12 years of age were enrolled in the prospective study in which the mTR device was implanted in the stifle joint to replace the ruptured CCL. The dogs were graded using the Bologna Healing Stifle Injury Index (BHSII) and radiographic osteoarthritis (OA) scores. Results: The outcomes obtained at the time of the surgery (T0) and for the following 12 months (T12) showed an improvement in the functional parameters (BHSII from a median of 74.3 [range, 58.1–82.4] at T0 to 95.6 [range, 94.1–99.3] at T12]). The OA did not change in 3 dogs and increased by only 1 point in 2 dogs. Conclusions: In this preliminary study, the mTR was a successful and repeatable intra-articular surgical procedure for all dogs. Additional studies related to the clinical application of the technique in medium-large dogs should be encouraged.

Effects of intertrochanteric varus osteotomy on Norberg angle and percent coverage of the femoral head in displastic dogs

Stefania Pinna,Enrico Pizzuti,Fabio Carli 대한수의학회 2013 JOURNAL OF VETERINARY SCIENCE Vol.14 No.2

This study was conducted to assess the effects of femoral varus osteotomy on joint congruency in dogs affected by early stage hip dysplasia. Preoperative planning to move the femoral head within the acetabulum was carried out. Varisation of the femoral inclination angle (fIA) was achieved by Intertrochanteric Osteotomy (ITO). Norberg angle (NA),percent coverage (PC) of the femoral head by the acetabulum and fIA was measured from preoperative, immediate postoperative and first and second recheck radiographs of seven dogs that underwent an ITO (joint n = 9). There was significant (p < 0.05) improvement of both NA and PC in all patients as indicated by a change in the mean ± standard deviation of 78.9o ± 7.5 and 36.9% ± 5.2 to 92.2o ± 6.7 and 50.6% ± 8.3, respectively. No significant difference (p < 0.05)was observed between the values of the planned femoral inclination angle (pfIA) of the femur and the effective femoral inclination angle (efIA) obtained after surgery (115.9o ± 2.5and 111.3o ± 6.4, respectively). These findings could encourage the use of ITO in veterinary practice and indicate that intertrochanteric varus osteotomy should be re-considered for the treatment of early stage hip dysplasia in dogs with radiological signs of joint incongruency.

Buckling of monopod bucket foundations-influence of boundary conditions and soil-structure interaction

Madsen, Soren,Pinna, Rodney,Randolph, Mark,Andersen, Lars V. Techno-Press 2015 Wind and Structures, An International Journal (WAS Vol.21 No.6

Using large monopod bucket foundations as an alternative to monopiles for offshore wind turbines offers the potential for large cost savings compared to typical piled foundations. In this paper, numerical simulations are carried out to assess the risk of structural buckling during installation of large-diameter bucket foundations. Since shell structures are generally sensitive to initially imperfect geometries, eigenmode-affine imperfections are introduced in a nonlinear finite-element analysis. The influence of modelling the real lid structure compared to classic boundary conditions is investigated. The effects of including soil restraint and soil-structure interaction on the buckling analysis are also addressed.

Biceps femoris muscle transposition for treatment of cranial cruciate ligament rupture in small breed dogs

Roberto Tamburro,Stefania Pinna,Anna Maria Tribuiani,Alessandra Panacea,Fabio Carli,Antonio Venturini 대한수의학회 2012 Journal of Veterinary Science Vol.13 No.1

The purpose of this study was to evaluate a new extracapsular surgical technique for the treatment of cranial cruciate ligament rupture in small breed dogs. Nine small breed dogs (seven females and two males) weighing ≤ 15 kg were treated with biceps femoris muscle transposition (BFT). The duration of the BFT procedure was 20 min. Each patient underwent a standard clinical protocol and a questionnaire for the owners. Follow-up (at 1, 3, and 12 months postoperative) confirmed significant improvement in all patients, especially at 1 month postoperatively (p < 0.01) and again after complete stifle joint assessment at 3 months postoperatively. After 12 months, only two patients showed a slight increase in osteoarthritis. According to our results, BFT is a simple extracapsular surgical technique that can be used for the treatment of cranial cruciate ligament rupture in small breed dogs.

Selective deposition of Pt onto supported metal clusters for fuel cell electrocatalysts.

Jeon, Tae-Yeol,Pinna, Nicola,Yoo, Sung Jong,Ahn, Docheon,Choi, Sun Hee,Willinger, Marc-Georg,Cho, Yong-Hun,Lee, Kug-Seung,Park, Hee-Young,Yu, Seung-Ho,Sung, Yung-Eun RSC Pub 2012 Nanoscale Vol.4 No.20

<P>We report a new method for deposition of Pt on a metal core to develop real electrocatalysts with significantly reduced amounts of expensive Pt as well as enhanced activity for oxygen reduction reaction. Ru and Pd have different crystal structures and modify the electronic structure of Pt to a different extent (shifts in d-band center). They were chosen as core materials to examine whether hydroquinone dissolved in ethanol can be used to deposit additional Pt atoms onto preformed core nanoparticles, and whether the modified d-character of Pt on different host metals can result in the enhanced ORR activity. The physicochemical characteristics of Pd-Pt and Ru-Pt core-shell nanoparticles are investigated. The core-shell structure was identified through a combination of experimental methods, employing electron microscopy, electrochemical measurements, and synchrotron X-ray measurements such as powder X-ray diffraction, X-ray absorption fine structure, and X-ray photoelectron spectroscopy. The hydroquinone reduction method proved to be an excellent route for the epitaxial growth of a Pt shell on the metal cores, leading to enhanced ORR activities.</P>

Atomic Layer Deposition of Nanostructured Materials for Energy and Environmental Applications

Marichy, Catherine,Bechelany, Mikhael,Pinna, Nicola WILEY‐VCH Verlag 2012 Advanced Materials Vol.24 No.8

<P><B>Abstract</B></P><P>Atomic layer deposition (ALD) is a thin film technology that in the past two decades rapidly developed from a niche technology to an established method. It proved to be a key technology for the surface modification and the fabrication of complex nanostructured materials. In this Progress Report, after a short introduction to ALD and its chemistry, the versatility of the technique for the fabrication of novel functional materials will be discussed. Selected examples, focused on its use for the engineering of nanostructures targeting applications in energy conversion and storage, and on environmental issues, will be discussed. Finally, the challenges that ALD is now facing in terms of materials fabrication and processing will be also tackled.</P>

Buckling of monopod bucket foundations—influence of boundary conditions and soil–structure interaction

Søren Madsen,Rodney Pinna,Mark Randolph,Lars V. Andersen 한국풍공학회 2015 Wind and Structures, An International Journal (WAS Vol.21 No.6

Using large monopod bucket foundations as an alternative to monopiles for offshore wind turbines offers the potential for large cost savings compared to typical piled foundations. In this paper, numerical simulations are carried out to assess the risk of structural buckling during installation of large-diameter bucket foundations. Since shell structures are generally sensitive to initially imperfect geometries, eigenmode-affine imperfections are introduced in a nonlinear finite-element analysis. The influence of modelling the real lid structure compared to classic boundary conditions is investigated. The effects of including soil restraint and soil–structure interaction on the buckling analysis are also addressed.

Colloidal polymers from inorganic nanoparticle monomers

Hill, Lawrence J.,Pinna, Nicola,Char, Kookheon,Pyun, Jeffrey Elsevier 2015 Progress in polymer science Vol.40 No.-

<P><B>Abstract</B></P> <P>The use of preformed inorganic nanoparticles as “colloidal monomers” has received recent attention for the formation of one-dimensional (1-D) mesostructures, or “colloidal polymers.” These colloidal monomers form linear assemblies through attractive, directional, interparticle interactions, which are similar to covalent or supramolecular interactions in classical polymer science. However, in contrast to the high degree of structural control available in the synthesis of classical molecular polymers, methods to control fundamental structural features such as chain length (DP), composition (copolymers), and architecture (linear, branched, etc.) are still being developed for NP-based colloidal polymer systems. We therefore review the colloidal polymerization of inorganic nanoparticle monomers by applying the conceptual framework provided by polymer science to categorize these novel systems. The descriptive nomenclature used for classical polymers is applied to NP assembly to define more explicitly the types of colloidal polymers formed in terms of DP, architecture, and composition (for binary NP assemblies). This review includes descriptions of inorganic nanoparticle types useful for the formation of colloidal polymers with examples chosen to demonstrate control over mesoscopic structure and composition. The various emergent optical, electrical and electrochemical properties from these materials are also reviewed and correlated with structural control achieved in various colloidal polymer systems.</P>