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      • KCI등재

        교차로 제약과 지연이 있는 네트워크에서 최단경로탐색

        박찬규,박순달,진희채 한국경영과학회 1998 韓國經營科學會誌 Vol.23 No.3

        Shortest path problem in road network with turn penalties and prohibitions frequently arises from various transportation optimization models. In this paper, we propose a new algorithm for the shortest path problem with turn prohibitions and delays. The proposed algorithm maintains distance labels of arcs, which is similar to labels of nodes of Dijkstra's algorithm. Fibonacci heap implementation of the proposed algorithm solves the problem in O(mn+mlogm). We provide a new insight in transforming network with turn penalties and prohibitions into another network in which turn penalties and prohibitions are implicitly considered. The proposed algorithm is implemented using new data structure and compared with Ziliaskopoulos' algorithm. Computational results show that proposed algorithm is very efficient.

      • KCI등재

        GIS를 이용한 네트워크 최적화 시스템 구축

        박찬규,이상욱,박순달,성기석,진희채 한국경영과학회 2000 經營 科學 Vol.17 No.1

        By managing not only geographical information but also various kinds of attribute date, GIS presents useful information for decision-makings Most of decision-making problems using GIS can be formulated into network-optimization problems in this study, we deal with the implementation of network optimization system that extracts data from the database in GIS, solves a network optimization problems, and present optimal solutions through GIS' graphical user interface We design a network optimization system, and present some implementation techniques by showing a prototype of the network optimization system Our network optimization system consists of three components the interface module for user and GIS, the basic network optimization program module, the advanced network optimization program module To handle large-scale networks, the program module including various techniques for large sparse networks is also considered For the implementation of the network optimization system, we consider two approaches the method using script languages supported by GIS, and the method using client tools of GIS Finally, some execution results displayed by the prototype version of network optimization system are given

      • Protein Binder for Affinity Purification of Human Immunoglobulin Antibodies

        Heu, Woosung,Choi, Jung-Min,Lee, Joong-Jae,Jeong, Sukyo,Kim, Hak-Sung American Chemical Society 2014 ANALYTICAL CHEMISTRY - Vol.86 No.12

        <P>The importance of a downstream process for the purification of immunoglobulin antibodies is increasing with the growing application of monoclonal antibodies in many different areas. Although protein A is most commonly used for the affinity purification of antibodies, certain properties could be further improved: higher stability in alkaline solution and milder elution condition. Herein, we present the development of Fc-specific repebody by modular engineering approach and its potential as an affinity ligand for purification of human immunoglobulin antibodies. We previously developed the repebody scaffold composed of Leucine-rich repeat (LRR) modules. The scaffold was shown to be highly stable over a wide range of pH and temperature, exhibiting a modular architecture. We first selected a repebody that binds the Fc fragment of human immunoglobulin G (IgG) through a phage display and increased its binding affinity up to 1.9 × 10<SUP>–7</SUP> M in a module-by-module approach. The utility of the Fc-specific repebody was demonstrated by the performance of an immobilized repebody in affinity purification of antibodies from a mammalian cell-cultured medium. Bound-antibodies on an immobilized repebody were shown to be eluted at pH 4.0 with high purity (>94.6%) and recovery yield (>95.7%). The immobilized repebody allowed a repetitive purification process more than ten times without any loss of binding capability. The repebody remained almost intact even after incubation with 0.5 M NaOH for 15 days. The present approach could be effectively used for developing a repeat module-based binder for other target molecules for affinity purification.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2014/ancham.2014.86.issue-12/ac501158t/production/images/medium/ac-2014-01158t_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ac501158t'>ACS Electronic Supporting Info</A></P>

      • SCOPUSKCI등재

        Effects of a Gelatin Coating on the Shelf Life of Salmon

        Heu, Min-Soo,Park, Chan-Ho,Kim, Hyung-Jun,Lee, Dong-Ho,Kim, Jin-Soo The Korean Society of Fisheries and Aquatic Scienc 2010 Fisheries and Aquatic Sciences Vol.13 No.2

        This study was conducted to investigate the efficacy of using a coating of gelatin extracted from refiner discharge to extend the shelf life of salmon during cold storage ($5^{\circ}C$). Relative percentage of moisture loss in gelatin-coated salmon during cold storage was less than that of uncoated salmon. The treatment of salmon with gelatin reduced volatile basic nitrogen (VBN) formation throughout the entire storage period. Measurements of the peroxide value (POV), fatty acid composition, and (20:5n-3+22:6n-3)/16:0 ratio during cold storage indicated that the coating of salmon with gelatin from refiner discharge effectively suppressed lipid oxidation over the entire storage period. The extent of sensory color change during cold storage was less in the gelatin-coated than in the uncoated salmon. From the results of chemical measurements, such as relative moisture content, VBN, POV, fatty acid composition, (20:5n-3+22:6n-3)/16:0 ratio, and sensory color change, the conclusion was made that the coating treatment of salmon with refiner discharge gelatin effectively suppressed moisture loss, lipid oxidation, and color deterioration over the entire storage period.

      • KCI등재

        수도 매끄러운엽 품종과 껄끄러운엽 품종에 있어서의 벼멸구 저항성, 수량성 및 제현비율의 비교

        Heu M. H,S. Z. Park,E. W. Lee,S. Y. Choi 韓國作物學會 1980 Korean journal of crop science Vol.25 No.2

        수도에 있어서 원활엽형질의 이용성을 검토하기 위하여 껄끄러운 잎의 품종과 매끄러운 잎의 품종에서 벼멸구저항성이 있는 것, 없는 것을 공시하여 원활엽형질이 벼멸구의 식이선호성과 우해율에 미치는 영향을 비교하고, 매끄러운 잎을 가친 품종과 껄끄러운 잎을 가진 품종의 수량 및 제현비율을 비교하였다. 그 결과를 요약하면 다음과 같다. 1. 벼멸구의 식이선호성, 우해율 및 항충성은 찰과메에 껄끄러운 형질 및 찰과메에 따라 차가 나타나지 않았다. 2. 지엽중의 SiO2/N 비율과 수량은 여리 N시용수준에 있어서 잎의 매끄러운 형질과 절끄러운 형질에 따라 차가 나타나지 않았다. 3. 매끄러운 잎을 가진 계통은 껄끄러운 잎을 가진 계통보다 우해율이 높았는데 메에 있어서만 유의하였다. 4. 매끄러운 잎을 가진 품종의 효용성을 검토하였다. Comparisons were made between pubescent and smooth leaved cultivars or lines for the brown planthopper feeding preference, adult emergence percent, nymphal period, grain yield and brown rice recovery percent, and found that there were no significant differences of the traits tested between smooth and pubescent.

      • Frosting and defrosting behavior of slippery surfaces and utilization of mechanical vibration to enhance defrosting performance

        Heu, Chang Sung,Kim, Sun Woo,Kim, Jihyun,Lee, Seojin,Kim, Jin Man,Lee, Kwan-Soo,Kim, Dong Rip Elsevier 2018 INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER - Vol.125 No.-

        <P><B>Abstract</B></P> <P>We experimentally investigate the frosting and defrosting performance of slippery surfaces which have low sliding angles of water droplets and low ice adhesion strengths. The frosting and defrosting characteristics of slippery surfaces are compared with those of bare aluminum, hydrophilic, and superhydrophobic surfaces. The enhanced sliding properties of water droplets on the slippery surfaces effectively promote the drainage of the condensate on their surfaces, which not only leads to significant frost retardation under frosting conditions, but also substantially reduces the mass of the retained water on the surfaces after defrosting by heat. In addition, when mechanical vibration is applied together with heating during defrosting process, the low ice adhesion strengths of the slippery surfaces enable the effective detachment of the lumped frost layer from their surfaces, thereby significantly reducing the defrosting time.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Frosting and defrosting performance of slippery surfaces are experimentally investigated. </LI> <LI> Slippery surfaces lead to effective frost retardation and reduced retained water after defrosting. </LI> <LI> The effects of applying mechanical vibration to heat defrosting of slippery surfaces are studied. </LI> <LI> Slippery surfaces exhibit significant reduction of defrosting time with mechanical vibration. </LI> </UL> </P>

      • SCOPUSKCI등재

        Partial Purification of Antioxidative Peptides from Gelatin Hydrolysates of Alaska Pollock Surimi Refiner Discharge

        Heu, Min-Soo,Park, Chan-Ho,Kim, Hyung-Jun,Park, Jae-W.,Kim, Jin-Soo The Korean Society of Fisheries and Aquatic Scienc 2009 Fisheries and Aquatic Sciences Vol.12 No.4

        This study is conducted to partially purify an antioxidative peptide in a two-step gelatin hydrolysate from Alaska pollock surimi refiner discharge, which was obtained by sequential treatment with Pronase E and Flavourzyme. The two-step gelatin hydrolysate was fractionated using chromatographic methods. Based on the same protein concentration of each fraction, the antioxidative activities (85.1-95.4%) of positive fractions fractionated by ion-exchange chromatography were higher than those (27.2-87.8%) from gel filtration. Then, further purification of the positive fractions was performed. Among them, the partially purified A1C1L2G1 and A1C1L2G2 fractions showed 96.2% and 85.1% inhibition, respectively, of linoleic acid peroxidation. The A1C1L2G1 fraction was composed of 15 kinds of amino acids and the predominant amino acids were proline, glycine and alanine. The results obtained in this study suggested that the fraction partially purified through chromatographic methods from the two-step gelatin hydrolysate of Alaska pollock surimi refiner discharge could be useful as a supplementary source for improving health functionality.

      • KCI등재후보

        水稻 品種間 交雜에 交雜에 있어서 稈長의 稈長의 遺傳分離 Ⅶ. 劣性稈長 特性의 遺傳分離

        Heu. M. H(許文會),Y. K. Kim(金容權) 한국육종학회 1984 한국육종학회지 Vol.16 No.1

        A rice genetic stock “Davis 80”, which has recessive tall uppermost internode designated as eui, was crossed with 2 Tongil Type semi-dwarf cultivar ωχ 817 and Nampung, one semi-dwarf Japonica Reimei, 2 tall Japonica Han #7 and Jinheung, and the culm length and the internode lengths were tested for their parents, F₁s and F₂S. The results are summarized as follows ; 1. The culm length of F₁ plants of Nampung cross was same as short parent Nam.pung, and in the rest combinations the culm length of F₁s were in between short and tall parents. 2. For the culm length of F₂s, in the crosses of Davis 80/ωχ 817, Davis 80/ Nampung and Davis 80/ Reimei, short and tall segregated in to 3 to 1 ratio. But the mode of the short and the tall group were significantly taller than their short and tall parents. In the crosses of Davis 80/Han #7 and Davis 80/Jinheung the segregation mode was typical non-allelic one. 3. For the first internode length of F₂s, in the crosses of Davis 80/Reimei and Davis 80/Jinheung showed 3:1 ratio segregation for short and long. In the rest combinations, the segregation modes were non-allelic. 4. The correlation coefficients between culm length and each internode length were significant. Especially, for those of 1st, 3rd and 4th were highly significant. 5. The correlation coefficients between culm length and heading time, panicle length, panicle exsertion and thickness of panicle neck were significant. The correlation cofficients between culm length and heading time were negative in the early F₂ populations and positive in the late F₂ populations.

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