기관의 용골부위에서 발생한 염증근섬유모세포종 1예

고은석,권계원,김희경 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Inflammatory myofibroblastic tumor is an uncommon, benign tumor of various organ and tissue which is vary rare in the carina of the trachea. We report a 36-year-old male patient with inflammatory myofibroblastic tumor arising in the carina of the trachea. Histologically, the tumor was composed of mainly myofibroblastic cells a few lymphoplasma cells.

우울증 환자의 혈당에 관한 연구

고희숙,김광일 大韓神經精神醫學會 1980 신경정신의학 Vol.19 No.3

In the biochemical study of depression, research interest has been focused mainly on the metabolism of neurotransmitters. Meanwhile, several researchers have paid attention to the blood sugar change in depression. Pryce (1958), van-Praag(1965), Muller, Heninger & McDonald(1969) and Diebold(1976) proved that blood sugar level was increased during active phase of depression and decreased by recovery, while, Herzberg, Coppen & Marks(1968) reported opposite result. The authors have tried to confirm the changes of blood sugar in depression with special regard to patterns of the changes in diagnostic subgroups of depression. Fifty six in-patients were initially selected for the study. But out of 56 subjeets, 22 were discarded; 12 subjects were lost because of their early discharge, two cass of thyroid dysfunction, two of diabetes mellitus and 6 with history of antidepressant medication previously at the out-patient clinic were excluded in this study. Among 34 subjects, 16 were retarded depression, 5 were agitated depression and 13 were secondary depreesion which was observed in borderline and hysterical personality disorders and recovered schizophrenia. Fasting blood sugar level was checked on the first, third, fifth days of admission, then weekly basis till fifth week. Hamilton's Rationg Scale for depression was used in symptom evaluation on the days of blood sampling. Fasting blood sugar level of retarded depression was higher than that of secondary depression. However, this increase was within normal limit. On the other, two subgroups could be identified according to the pattern of blood sugar level; typical and atypical groups. Typical group was a state in which manifested increased FBS level in the initial phase of treatment then slow decrease as symptom improvement. Atypical group was a state in which manifested irregular FBS level on the course of illness without initial increase. Fifty percent of retarded depression, 20 percent of agitated depression, and 15.4 percent of secondary depression were the typical group. The amount of food intake revealed no difference between the typical and atypical groups. According to factor analysis of Hamilton's rating scale, factor Ⅰ, Insomnia, was more prominent in typical group and factor Ⅴ, Somatic Delusion, in atypical group. Symptom improvement was faster in typical group for 6 days than atypical group. Tricyclic antidepressant and phenothiazine seemed to have no effect on the FBS level. In the typical group, the increased FBS decreased gradually and maintained steady level in one to two weeks, and symptom improvement was followed six to thirteen days later.

絃樂4重奏

高羲駿 淸州大學校 1983 論文集 Vol.16 No.2

This composition is composed in an attempt to express atonal or contemporary idioms escaped from tonal and traditional idioms, and hence it tried to show the strict structure or dissonance, and augumentation and diminuation. In addition, an important melody line, which is not abstract, has been partially continued in each part focussing at the pattern of melody line which is escaped from the tonal idioms and is dissonant. Moreover, the composer has made another attempt to follew the effects of counterpoint by the structure of of a variety of different rhythms and to follow strictly the various rules of atonal idioms.

短期 最大電力 需要豫淨에 관한 硏究

高羲石,李壽欽 慶南大學校 附設 工業技術硏究所 1986 硏究論文集 Vol.4 No.-

본 논문은 부하성장곡선이 한정된 해에서 지수적인 성장특성을 갖는다는 사실에 입각하여 최소자승법을 사용함으로써 단기 최대전력수요의 예측기법을 논하였다. 한전계통에 시험했고, 이 기법이 단기 최대전력수요예측에서 만족하게 사용되어 질 수 있다는 사실이 증명되었다. Since maximum power demand forecasting paves the way to electric power system planning, the improvement of its precision exerts a great influence upon the reliability and the economic relation of power supply. This paper discusses the technique of load forecasting to meet future demand of electricity with the use of the method of least squares basing on the fact that the load growth curve has been exponential in form over a limlted number of years. Specific case of the load growth for the present Korea power system has been examined and it is apparent that this technique is capable of being used satisfactorily for forecasting short-term maximum power demand.

氣象狀態를 考慮한 長期最大電力 需要豫測에 관한 硏究

高羲石 慶南大學校 附設 工業技術硏究所 1985 硏究論文集 Vol.3 No.-

長期最大電力 需要豫測은 電力系統計劃의 基礎가 되므로 그 精度를 높이는 것은 電力供給의 信賴性과 經濟性에 큰 影響을 미친다. 특히 産業社會 高度化와 國民生活水準의 向上에 따라 우리나라의 日 最大電力需要도 冬季 12月의 點燈時에 발생하든것이 電氣冷房空調設備의 확대보급에 의하여 1981年이후 夏季 8月의 낮시간으로 移行하였다. 따라서 이 論文에서는 有用한 과거資料를 이용하여 最大電力需要를 溫度에 敏感하지 않은 非氣象感應成分과 溫度에 敏感한 氣象感應成分으로 나누고 이 양 成分을 결합함으로써 柔軟性을 높였다. 이 目的에서 平日 最大電力과 同時乾球溫度에 대한 散亂圖를 그리고 여기에서 最小 自乘法을 이용하여 基底成分과 氣象感應成分이 얻어진다. 基底需要成分이 불규칙하게 변할지라도 여러 傾向曲線중 指數曲線으로서 年基底成分이 回歸 예측되고 氣象感應成分은 實數 2次式의 年 기상부하모델係數를 回歸시킴으로써 豫測된다. 이렇게 하여 얻어진 兩成分을 결합시켜 回歸함으로써 最大電力需要가 예측된다. 여기서 夏冬季의 일관성은 유지하기 위하여 여러다른 氣象因子중 最大電力發生時의 同時乾球溫度만을 취한다. 提示된 알고리즘(Algorithm)의 效用性을 證明하기 위하여 韓電系統에 적용시켜 多重回歸分析技法의 타당성이 評價되었고 만족한 結果를 얻었다. Since the long-term maximum power demand forecasting paves the way to electric power system planning, the improvement of its precision exerts a great influence upon the reliability and the economic relation of power supply. Especially, as industrial society is growing higher, and as the standard of our living is gradually imgroving. The Korean daily maximum power demand which was marked at the Winter liphting time of December, shifted its peak time to the Summer daytime of August, which has remained since 1981 owing to the expansion caused by far more use of electric cooling and air conditioning equipment. This paper, with the above fact taken into consideration, is prepared to forecast the power system maximum demand, with the use of the available past data, to separate the non-weather sensitive component which is not sensitive to temperature, and the weather sensitive component which is sensitive to temperature, and further to raise the flexibility by means of so integrating both components as to work for a proper forecasting. For this purpose, the scatter diagrams of weekday maximum power versus coincident dry-bulb temperature are first drawn every year, using the coincident temperature which shows the coincidence with daily maximum power; and from the diagrams it is possible to obtain both annual base component and weather sensitive component by using the method of least square from the data of temperature and weekday maximum power. Even the base demands obtained in the proceeding may change randomly, we are able to forecast the yearly base demands through forecasting a long-term growth by reference to the exponential curve among various trend curves. Putting the figure of base demands into regression to the year concerned, the weather sensitive components make it possible to forecast the value of each year in regression of annual weather load model coefficients to quadratic equation. With the base components thus obtained, joining with the weather sensitive components of maximum power and letting it regress, it is put to interpolation for the past years and into extrapolation up to the year in concern of forecast. Though it is easily imagined that there are many weather factors influential on weather, such as temperature, humidity, discomfortable index, precipitaiton, and wind velocity, this paper makes use of only coincident dry bulb temperature with the maximum power demand collected easily for general survey as weather factor to keep the consistency between summer and winter seasons. And to prove the applicability of suggested algorithm, the various figures concerned are calculated with the present Korean power system, this paper evaluated the validity of technique of multiregression analysis and obtained the satisfactory results.

질소이용효율이 높은 벼품종 육성 연구

고희종 서울대학교 농업개발연구소 1999 농업생명과학연구 Vol.3 No.-

Crop variety having high nutrient-use efficiency is a prerequisite to meet the need of environment-friendly crop cultivation. A few studies on genetics and breeding for physiological nitrogen-use efficiency (PNUE; grain yield /absorbed N) in rice initiated recently with the elucidation of varietal differences, which suggested the possibility of high PNUE varieties. A project for breeding high PNUE rice varieties has been carried out in our laboratory, and the results obtained so far are briefly summarized here. Genotypic variations in PNUE under both N-fertilized (100kg/ha) and unfertilized conditions were significantly high using varieties of various origin and plant architecture, and PNUE was much higher in improved HYV than in land varieties. Path analysis revealed that harvest index was a major character contributing to PNUE. PNUE was lowered by the heavy application of N fertilizer. The variances of general combining ability for yield-related characters were higher than the variances of specific combining ability in both N-fertilized and unfertilized conditions, indicating that additive effects were more important than dominance effects. Dasanbyeo and Guichow out of parents were the best combiners for biomass production, yield, and crop growth rate in F1. Genetic similarities among parents were estimated to be useful in predicting the yield heterosis in F1 under N-fertilized condition. The genetic segregations of dry-matter and PNUE in F2 were continuous. Heritabilities for yield-related characters varied along characters and populations. Heritabilities for yield were increased with generation advance and were much higher in N-unfertilized condition than in N-fertilized condition. Genetic gain after selection for yield was significantly higher in N-unfertilized condition than in N-fertilized condition. However, the selection response for yield was negligible in case that the plants were grown in N-unfertilized condition after selection in N-fertilized condition and vice versa. Selection for PNUE in early generations was effective in both N-fertilized and -unfertilized conditions, implying that high PNUE lines could be bred by selection after hybridization. Promising lines having both high yield and high PNUE were selected in F3 and F4. The selection with generation advance for the lines is in progress for genetic fixation.

벼의 아종간 재조환 극대화를 위한 아종간 특이적인 DNA 마커 탐색

고희종 서울대학교 농업개발연구소 2000 농업생명과학연구 Vol.4 No.-

The subspecies-specific RAPD markers using 30 varieties(15 japonica, 15 indica) of various origin could be detected. Of the 526 random primers tested, 54 subspecies-specific DNA bands were identified. Although RAPDs were less polymorphic than URP(random eicosamer primer) bands, the proportion of subspecies-specific markers by RAPD was higher than those by by URP. 54 subspecies-specific markers consisted of 25 japonica-specific markers and 29 indica-specific markers. Rice varieties were classified into two discrete subspecies by subspecies-specific markers. The SPV(subspecies prototype variety) concept was introduced representing the typical varieties to each subspecies. 10 JPVs(japonica prototype species) and 4 IPVs(indica prototype species) were selected. The breeding lines from cross between Dasanbyeo(indica) and TR22183(japonica) was analyzed by selected subspecies-specific markers. All the lines turned out to be genetically closer to indica parent. Dasanbyeo.

찰벼 신소재 개발

고희종 서울대학교 농업개발연구소 2001 농업생명과학연구 Vol.5 No.-

Waxy rice lines of diversified qualities were developed by chemical mutagenesis and by introgressing the mutated genes for grain quality into waxy varieties. The low-amylose endosperm trait of a mutant line du-6 was expressed in case of homozygotic pairing of two independent recessive genes. The gene of low amylose endosperm of Du-7 showed a lethal effect on pollens and was transmitted into the progeny through only female parent. The flo(flourOy), su(sugary), and shr(shrunken) genes were transmitted to the F2 progenies independently with wx(waxy) gene. However, it was revealed that wx(waxy) gene was epistatic over du-1(dull) gene. Low-amylose mutant lines induced from the normal line had very low amylose content, 7.0∼10.4%. Sugary lines and giant embryo lines showed more lysine content. Giant embryo waxy lines revealed much more lipid content than the parent variety. Floury waxy and sugary waxy lines showed increased protein content, 9.0∼10.3%. Some waxy lines developed showed greater Ca^2+, Fe^2- and riboflavin content. Lines developed will be applicable for practical use as highly nutritive rices.

가변수를 이용한 최대 전력수요예측

고희석,이충식 慶南大學校 附設 工業技術硏究所 1999 硏究論文集 Vol.17 No.-

본 연구에서는 최대전력수요를 예측하기 위하여 다중회귀모델을 구축하고, 질적변수를 가변수(Dummy Variable)로 만들어 설명변수로 사용하는 기법을 제시한다. 5가지 예측모델을 기온-습도, 불쾌지수와 가변수로 구성하고, 최대전력수요를 예측한 결과 가변수를 이용한 모델에서는 모델 4의 경우 예측 오차율이 3[%] 정도로 가장 양호한 결과가 나왔다. 따라서 질적변수를 가변수화 하여 설명변수로 이용하는 것이 가능하게 되었다. This paper is presented the method of peak load forecast based on multiple regression Model, and to make explanatory variable using dummy variable of qualitative variable. Forecasting model of five type was composed of the temperature-humidity, the discomfort index and dummy variable Forecasting result of Model 4 in the model using dummy variable was very good with about 3[%]. Therefore it was possible that use explanatory variable using dummy variable of qualitative variable.

CW Laser Annealing 과정중 SOS 상의 시간적 온도변화 측정에 관한 연구

고년규,윤희중,유동선,최원국,문경순 연세대학교 대학원 1987 延世論叢 Vol.23 No.1

The purpose of this experiment is to demonstrate the new method of TSRTM during CW Ar laser annealing using a He-Ne laser probe beam. Optical interference phenomena by a small changes of refractive index of Si, which is induced by the temperature change during short time laser annealing on the Si wafer surface, was used. The samples, SOS(Silicon on Sapphire), used in this work were epi. <100> Si grown on a <1012> insulator sapphire substrate with 2.0μm thickness. From the experimental temperature dependent equation of the refraction of index of Si with respect to the probe beam(λ=6328 Å) in furnace experiment, n(T)=3.98+7×10-4T (℃), the temperature on the destructtve or constructive interference was calculated. Incident Ar laser beam whose power ranges from 1.8W to 2.8W was irradiated and the effect of temperature rise of Si wafer on the elliptical spot whose major and minor axis is 200μm, 15μm respectively is investigated by the He-Ne laser probe beam which is focused 30μm. The annealing time ranges from 8 msec~250 msec to 500 msec~20 sec was adopted to estimate that the first constructive interference is occurred at least total irradiated power density 5.46×102Jㆍsec/cm2, and it is inferred that more than 180msec is needed for the first constructive interference when the total incident energy is 2.8 W. For the longtime annealing, about more than 1 sec, the interference pattern was coincided with the result produced by the furnace experiment. It is investigated from the space-resolved temperature gradient that the irradiated laser beam was focused in center.