http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
An He,Perucho Jose AU,Chiu Keith WH,Hui Edward S,Chu Mandy MY,Ngu Siew Fei,Ngan Hextan YS,Lee Elaine YP 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.5
Objective: To investigate the association between functional tumor burden of peritoneal carcinomatosis (PC) derived from diffusion-weighted imaging (DWI) and overall survival in patients with advanced ovarian carcinoma (OC). Materials and Methods: This prospective study was approved by the local research ethics committee, and informed consent was obtained. Fifty patients (mean age ± standard deviation, 57 ± 12 years) with stage III–IV OC scheduled for primary or interval debulking surgery (IDS) were recruited between June 2016 and December 2021. DWI (b values: 0, 400, and 800 s/mm2) was acquired with a 16-channel phased-array torso coil. The functional PC burden on DWI was derived based on K-means clustering to discard fat, air, and normal tissue. A score similar to the surgical peritoneal cancer index was assigned to each abdominopelvic region, with additional scores assigned to the involvement of critical sites, denoted as the functional peritoneal cancer index (fPCI). The apparent diffusion coefficient (ADC) of the largest lesion was calculated. Patients were dichotomized by immediate surgical outcome into high- and low-risk groups (with and without residual disease, respectively) with subsequent survival analysis using the Kaplan-Meier curve and log-rank test. Multivariable Cox proportional hazards regression was used to evaluate the association between DWI-derived results and overall survival. Results: Fifteen (30.0%) patients underwent primary debulking surgery, and 35 (70.0%) patients received neoadjuvant chemotherapy followed by IDS. Complete tumor debulking was achieved in 32 patients. Patients with residual disease after debulking surgery had reduced overall survival (p = 0.043). The fPCI/ADC was negatively associated with overall survival when accounted for clinicopathological information with a hazard ratio of 1.254 for high fPCI/ADC (95% confidence interval, 1.007–1.560; p = 0.043). Conclusion: A high DWI-derived functional tumor burden was associated with decreased overall survival in patients with advanced OC.
An integrated structural health monitoring system for the Xijiang high-speed railway arch bridge
He, Xu-hui,Shi, Kang,Wu, Teng Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.21 No.5
Compared with the highway bridges, the relatively higher requirement on the safety and comfort of vehicle makes the high-speed railway (HSR) bridges need to present enhanced dynamic performance. To this end, installing a health monitor system (HMS) on selected key HSR bridges has been widely applied. Typically, the HSR takes fully enclosed operation model and its skylight time is very short, which means that it is not easy to operate the acquisition devices and download data on site. However, current HMS usually involves manual operations, which makes it inconvenient to be used for the HSR. Hence, a HMS named DASP-MTS (Data Acquisition and Signal Processing - Monitoring Test System) that integrates the internet, cloud computing (CC) and virtual instrument (VI) techniques, is developed in this study. DASP-MTS can realize data acquisition and transmission automatically. Furthermore, the acquired data can be timely shared with experts from various locations to deal with the unexpected events. The system works in a Browser/Server frame so that users at any places can obtain real-time data and assess the health situation without installing any software. The developed integrated HMS has been applied to the Xijiang high-speed railway arch bridge. Preliminary analysis results are presented to demonstrate the efficacy of the DASP-MTS as applied to the HSR bridges. This study will provide a reference to design the HMS for other similar bridges.
Optimal Design of a Tilling Machine Reduction Gearbox Using Matlab
Hui-Bo He,Hua-Ying Li,Sung-Ki Lyu,Sung-Hoon Tak,Sung-Min Moon,Qi Zhang 한국정밀공학회 2009 International Journal of Precision Engineering and Vol.10 No.2
This paper describes the optimal design of the reduction gearbox of a tillage machine. The minimum center diameter was selected as the objective, and the contact fatigue strength. bending fatigue strength, condition of nonintervention, and oil film thickness ratio of the gearbox were applied as constraint conditions. The optimal model was solved by a Matlab program. The results show that the center diameter of the reduction gearbox decreased by about 10%. The resulting decrease in weight and volume led to a reduction in the amount of gearbox matelial and a consequent decrease in production cost.
Distinguishing elliptic fibrations with AI
He, Yang-Hui,Lee, Seung-Joo North-Holland Pub. Co 2019 Physics letters. Section B Vol.798 No.-
<P><B>Abstract</B></P> <P>We use the latest techniques in machine-learning to study whether from the landscape of Calabi-Yau manifolds one can distinguish elliptically fibred ones. Using the dataset of complete intersections in products of projective spaces (CICY3 and CICY4, totalling about a million manifolds) as a concrete playground, we find that a relatively simple neural network with forward-feeding multi-layers can very efficiently distinguish the elliptic fibrations, much more so than using the traditional methods of manipulating the defining equations. We cross-check with control cases to ensure that the AI is not randomly guessing and is indeed identifying an inherent structure. Our result should prove useful in F-theory and string model building as well as in pure algebraic geometry.</P>
Research on the Cutting Performances and Wear Mechanisms of TiAlCrN Coated Tools during Dry Turning
Hui-Bo He,Hua-Ying Li,Xian-Ying Zhang,Qi-Bin Yue,Jun Zhang,Lu Ma,Yuan-ming Li 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.2
Physical vapour deposition technique was used to deposit TiAlCrN coatings on the YT15 tungsten carbide inserts. The dry turning tests of 20CrMo steel were carried out to evaluate performances of TiAlCrN coated and uncoated tools on the CA6140A lathe. The effect of the two kinds of tools on cutting forces, cutting temperature, surface roughness and tool wear had been investigated to assess the performance of TiAlCrN coated tools. The results showed that the cutting force and cutting temperature obtained by TiAlCrN coated tools were decreased and the TiACrN coated tools produced a better surface finish in comparison with the uncoated tools. The TiAlCrN coated tools yield working life about 45 min, which was two times of that for uncoated tools. The wear mechanisms of the TiAlCrN coated tools were mainly oxidation and boundary wear, accompanied with diffusion wear.
A Study on Major Factors Influencing Dry Cutting Temperature of AISI 304 Stainless Steel
Hui-Bo He,Hua-Ying Li,Jun Yang,Xian-Yin Zhang,Qi-Bin Yue,Xue Jiang,류성기 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.10
TiN coated and uncoated tools were used to conduct the dry cutting temperatures for AISI 304 stainless steel. Effects of cutting variables on cutting temperatures were investigated using single factor experiment method. The optimal cutting parameters of cutting temperatures were obtained through orthogonal experiment method. The forming process and temperature distribution of chips were analyzed using finite element method (FEM). The results show that cutting temperature generally increases with the increase of cutting speed and feed rate. When depth of cut increases at the range of 0.8-1.5 mm, the cutting temperature increases firstly and decreases subsequently. And the cutting temperature of TiN coated tool is lower than that of uncoated tool. The optimal parameters of cutting temperature are obtained by orthogonal experiment, which is A1B1C3. The highest temperature appears on the second deformation zone by the simulation.
Hui Tan,Hui Ling,Jie He,Lan Yi,Jianguo Zhou,Min Lin,Qi Su 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.6
We investigated the effects of diallyl disulfide (DADS) on the induction of apoptosis in human Leukemia cell line HL-60 and explored the roles of mitogen-activated protein kinase (ERK and p38 MAPK) pathways in the growth inhibition and apoptosis induced by DADS. MTT assay was used to determine the DADS induced cell growth inhibition in HL-60 cells. Flow cytometry and DNA fragmentation were used to examine the roles of apoptosis in DADS-mediated cell death. Western blot analysis of the expression of phospho-MAPKs (ERK and p38) was employed to elucidate the possible mechanisms of DADS induced apoptosis. We found that growth inhibition of HL-60 cells treated with DADS exhibited a dose-dependent response (P<0.05) and DADS induced significant apoptosis. DADS at the concentration of 10 mg/L persistently activated p38 and simultaneously reduced ERK activity. PD98059, an inhibitor of ERK upstream activators MAPK kinase MKK1 and MKK2, promoted cytotoxicity and apoptosis in HL-60 cells treated with DADS. In contrast, SB203580, an inhibitor of p38, decreased cytotoxicity and apoptosis induced by DADS. Therefore, DADS can effectively inhibit the proliferation and induce apoptosis of human leukemia cell line HL-60. Inhibition of ERK signaling pathways and activation of p38 signaling pathways are likely involved in DADS induced apoptosis in HL- 60 cells.