5-HT and Intraplatelet 5-HT: a potential upstream regulator of YAP in liver regeneration

Chao He,Mimi Zhai,Bo Shu,Chaolin Deng,Li Liu,Sushun Liu 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

The injector-based regenerative supercritical organic Rankine cycle

Chao Liu,Xi Wang,Hong Gao,Cheng Zhang,Chao He 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.5

In order to improve the thermodynamic performance of the Supercritical organic Rankine cycle (SORC), the regenerative supercritical organic Rankine cycle with an injector (RORC) is presented. For the moderate temperature of waste heat, the thermodynamic performance of RORC and SORC are investigated by using the working fluid R123. The effects of extraction pressure, expander inlet temperature, expander inlet pressure and condensing temperature on the net power output and the thermal efficiency have been analyzed. The net power output of RORC is greater than one of SORC when the extraction pressure is lower than 0.45 MPa. When the extraction pressure is 0.6 MPa, the efficiency of RORC reaches the maximum (16.06%), which is 0.66% higher than one of SORC. This reveals that the performance of RORC is better than that of SORC.

Serum Protein and Genetic Tumor Markers of Gastric Carcinoma

He, Chao-Zhu,Zhang, Kun-He Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

The high incidence of gastric cancer and consequent mortality pose severe threats to human health. Early screening, diagnosis and treatment are the key to improve the prognosis of the patients with gastric cancer. Gastroscopy with biopsy is an efficient method for the diagnosis of early gastric cancer, but the associated discomfort and high cost make it difficult to be a routine method for screening gastric cancer. Serum tumor marker assay is a simple and practical method for detection of gastric cancer, but it is limited by poor sensitivity and specificity. Therefore, people have been looking for novel serum markers of gastric cancer in recent years. Here we review the novel serum tumor markers of gastric cancer and their diagnostic significance, focusing on the discoveries from serum proteomics analyses and epigenetics researches.

Effect of Dynamic Interaction of Two Neighboring Tunnels on Vibrations from Underground Railways in the Saturated Soil

Chao He,Shunhua Zhou,Honggui Di,Xinwen Yang 대한토목학회 2019 KSCE Journal of Civil Engineering Vol.23 No.11

This paper analytically investigates the dynamic interaction of two neighboring tunnels in the saturated soil. The twin tunnels are simulated using the Flügge shell theory, and the surrounding soil is modelled by the Biot's theory. The solution for cylindrical waves in saturated porous media is derived by applying the potential decomposition. The addition theorem is subsequently introduced to translate cylindrical waves, thereby satisfying the boundary conditions at the interfaces between the twin tunnels and saturated soil. Numerical examples are presented to analyze soil vibrations under different loading conditions calculated by different tunnel models. The neighboring tunnels have strong dynamic interaction, resulting in the insertion gain up to ± 20 dB. It is recommended to account for the interaction between neighboring tunnels when calculating the vibrations from underground railways.

Transformational Leadership, Psychological Capital and Front-line Sales Staffs’ Service Quality : Psychological Capital as a Mediator

Qi-chao He,Qiao An,Pu-xin Lin 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.7

Confronting diverse working pressure during office time, front-line sales staffs’ service quality will be threatened, which can affect customers’ satisfaction and loyalty degree, then influence market share and competitive edge of the company further. Thus, this paper focuses on the front-line sales staffs and aims at identifying the influence mechanism of transformational leadership on their service quality and the role of psychological capital among the triadic relationship. The result of hierarchy regression analysis about 250 sample data showed that both transformational leadership and psychological capital had significantly positive effect on front-line sales staffs’ service quality, while psychological capital acted as mediator between transformational leadership and front-line sales staffs’ service quality. Organizational management is advised to adopt transformational leadership and promote the employees’ level of psychological capital so as to improve the service quality of front-line sales staffs and the entire company.

Gestational weight gain of multiparas and risk of primary preeclampsia: a retrospective cohort study in Shanghai

Chen Chao,Lei Zhijun,Xiong Yaoxi,Ni Meng,He Biwei,Gao Jing,Zheng Panchan,Xie Xianjing,He Chengrong,Yang Xingyu,Cheng Weiwei 대한고혈압학회 2023 Clinical Hypertension Vol.29 No.-

Background In all studies conducted so far, there was no report about the correlation between excessive gestational weight gain (GWG) and the risk of preeclampsia (PE) in multiparas, especially considering that multiparity is a protective factor for both excessive GWG and PE. Thus, the aim of this retrospective cohort study was to determine whether GWG of multiparas is associated with the increased risk of PE. Methods This was a study with 15,541 multiparous women who delivered in a maternity hospital in Shanghai from 2017 to 2021, stratifed by early-pregnancy body mass index (BMI) category. Early-pregnancy body weight, height, week-specifc and total gestational weight gain as well as records of antenatal care were extracted using electronic medical records, and antenatal weight gain measurements were standardized into gestational age-specifc z scores. Results Among these 15,541 multiparous women, 534 (3.44%) developed preeclampsia. The odds of preeclampsia increased by 26% with every 1 z score increase in pregnancy weight gain among normal weight women and by 41% among overweight or obese women. For normal weight women, pregnant women with preeclampsia gained more weight than pregnant women without preeclampsia beginning at 25 weeks of gestation, while accelerated weight gain was more obvious in overweight or obese women after 25 weeks of gestation. Conclusions In conclusion, excessive GWG in normal weight and overweight or obese multiparas was strongly associated with the increased risk of preeclampsia. In parallel, the appropriate management and control of weight gain, especially in the second and third trimesters, may lower the risk of developing preeclampsia.

Uncovering Microstructure Evolution and Dynamic Softening Mechanism of Spray-Deposited AlZnMgCu Alloy Under Thermal Deformation

Guoai He,Cunxiao He,Yu Liu,Chao Liu,Zhiqiang Fu,Shuanghui Xu,Xiaofei Sheng,Zhu Xiao,Qinghong Wen 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

Dynamic softening behavior has been of great concern in the aluminum alloys, which served a vital role in affecting themicrostructure, deformation resistance and the final mechanical properties. In this paper, spray deposition was applied tomanufacture AlZnMgCu alloy to refine the casting microstructure and reduce segregation. The microstructure responses andcorresponding mechanism during the thermal compression with various temperatures and various strain rates were multiscalecharacterized and uncovered using high-resolution EBSD. The results revealed that many broken and fine grains wereobserved in the uneven and jagged grain boundaries under the low temperatures and high strain rates, which indicated theoccurrence of partial discontinuous dynamic recrystallization (DDRX). In addition, high density dislocations were formedat original grain boundaries, where great amount of low angle grain boundaries (LAGBs) were appeared. With temperatureincreased and strains rate decreased, the LAGBs would evolve to the high angle grain boundaries (HAGBs) owing to theconsiderable dislocations migrated to the grain boundaries then accumulated, which triggered the occurrence of continuousdynamic recrystallization (CDRX). Two different dynamic recrystallization types were observed and factors that influenceddifferent dynamic recrystallization behaviors were clearly elaborated, and the corresponding mechanism was indicateddetailly.

Numerical analysis of large stud shear connector embedded in HFRC

Yu Liang He,Chong Zhang,Li Chao Wang,Ying Yang,Yi Qiang Xiang 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.80 No.5

To investigate the mechanical behavior of large stud shear connector embedded in hybrid fiber-reinforced concrete (HFRC), a refined 3D nonlinear finite element (FE) model incorporating the constitutive model of HFRC was developed using ANSYS. Firstly, the test results conducted by the authors (He et al. 2017) were used to validate FE model of push out tests. Secondly, a total of 27 specimens were analyzed with various parameters including fiber volume fractions of HFRC, diameter of studs and HFRC strength. Finally, an empirical equation considering the contribution of steel fiber (SF) and polypropylene fiber (PF) was recommended to estimate the ultimate capacity of large stud shear connector embedded in HFRC.

The European Vulnerable Option Pricing Based on Jump-Diffusion Process in Fractional Market

Chao Wang,Jianmin He 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10

Assuming that the underlying asset is driven by a fractional Brownian motion with jumps, the interest rate and the default intensity are both following the Vasicek model, we derive the European vulnerable option pricing in fractional market. Then the martingale method and measure transformation are used to deduce the solution of it. On the other hand, the expression of jump process in the form of measure transformation is proved in this paper which can be regarded as a supplement of the Girsanov’s theorem. The results are tested through numerical experiments which show that the pricing model proposed in this paper can describe the changes of the financial asset well, it makes the pricing more accords with the realistic than Black-Scholes option pricing model.

Selection of reference genes for Harmonia axyridis (Coleoptera: Coccinellidae) feeding on different diets

Chao Liang,Shipeng Han,Hui Han,Feng Zhao,Yunzhuan He 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.4

The selection of a stable reference gene is vital to gene expression studies and to improving the accuracy of RTqPCR data. With the deep research on the artificial feed of the Harmonia axyridis, there is an increasing need to evaluate the effects of feed on insects at the molecular level. To identify a reference gene to assess the expression of related genes in Harmonia axyridis (Pallas), ensure the reliability of target gene expression analysis using realtime PCR. Especially for H. axyridis were fed Rhopalosiphum padi (L.) or an artificial diet. In this study, the expression profiles of nine candidate reference genes, including 28SrRNA, 18SrRNA, RPS23, EF1, Actin, ATPase, GAPDH, UBI, RPL13 from different H. axyridis tissues (head, thorax, wing, leg, ovary, and fat body) were investigated. The stability of the nine candidate genes was assessed using geNorm, NormFinder, BestKeeper and RefFinder software, and a comprehensive analysis showed that EF1 is a suitable reference gene for eating different diets of different organizations from H. axyridis. 28SrRNA, 18SrRNA, and RPS23 can also be used as reference genes, but Actin, ATPase, RPL13 are not suitable as an internal reference gene