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혈압점(血壓點)에 윤제(潤劑)의 주입이 고혈압에 미치는 영향
위종성,한재섭,박희수,박재영,Owi, Jong-Sung,Han, Jai-Seop,Park, Hee-Soo,Park, Jai-Young 대한약침학회 2002 Journal of pharmacopuncture Vol.5 No.1
Objective: This study was designed to evaluate the possibility of Hypertension by moistening Herbal-acupuncture at Blood Pressure Point(HN136). Methods: We reviewed 14 patients of Hypertension. They were hospitalized at oriental medical hospital of Sang-Ji university for 2002. 1. 2. - 2002. 5. 2. First, we divided into two groups; Group Ⅰ was administrated by moistening Herbal-acupuncture at Blood Pressure Point(HN136), and was not given any western medicine about Hypertension during the period of experiment. Group Ⅱ was administrated by moistening Herbal-acupuncture at Blood Pressure Point(HN136), and given western medicine about Hypertension during the period of experiment. we observed the change of systolic and diastolic for 2 weeks, and compared Group Ⅰ with Group Ⅱ . Results: The results obtained as follows: 1. The figure of systolic in Group Ⅰ was decreased, but there was no signification. There was a significant decrease in Group Ⅱ (p<0.05) 2. The figure of diastolic in Group Ⅰ was decreased, but there was no signification. There was a significant decrease in Group Ⅱ (p<0.05) 3. Group Ⅱ was more effective than Group Ⅰ in the results. Conclusion: The results suggest that moistening Herbal-acupuncture at Blood Pressure Point(HN136) was effective treatment of Hypertension. So further research is needed continuously.
Park, Jong Il,Han, sang seop,Jeong, Tae Cheon,Roh, Jung Koo,Kim, Hyoung Chin,Kim, Jeong Hwan,Jeon, Yeong Joong,Kim, Dal Hyun,Kim,Je Hak,Park, Kwan Ha 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.1
The antigenic potential of CFA-001, cefazolin, a cephalosporin derivative produced by an enzymatic semisynthesis, was determined in Hartley guinea pigs. A battery of tests employed consisted of active systemic anaphylaxis (ASA), passive cutaneous anaphylaxis (PCA), and indirect hemagglutination test (IHA). The results were as follows: 1) In ASA, no signs attributable to anaphylaxis was observed in guinea pigs sensitized with CFA-001, whereas OVA-sensitized animals induced severe anaphylactic symptoms; 2) guinea pigs did not produce antibodies against CFA-001 when sensitized with or without Freund's complete adjuvant (FCA) in homologous PCA tests. Meanwhile, antibodies against ovalbumin (OVA) were clearly detected; 3) No CFA-001-specific hemagglutination was observed in the IHA using sera obtained from CFA-001-sensitized guinea pigs. These results suggest that CFA-001 has no antigenicity potential in guinea pigs.
Accelerated Experiment for Edible Insect Expiration Date
Sang seop Cho,An na Kim,Nam sam Kim,So jin Han,Soo nil Hong,Yoon young Seol 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.04
식용곤충에서 최근에 식품공전에 등록된 갈색거저리 유충, 쌍별귀뚜라미 유충에 대해 일선 농가들이 식용곤충의 안정적 공급 및 유통을 위해 수확 후 건조 포장시 보관 유통기한을 설정할 필요가 있다. 건조된 갈색거저리, 쌍별귀뚜라 미 성상(분말, 건조물)을 용량 100g씩 PE, PET, 내습 포장지 등 포장재질에 진공, 밀봉포장을 한 후 저장온도를 45℃ 설정하여 2월 12일부터 3월 11일까지 1개월동안 가속실험을 실시하였다. 1개월후 시료 검체하여 품질 지표를 분석 조사한 결과, 밀봉포장에서 갈색거저리 건조물은 수분, 일반세균, 관능검사 등에서 PET+제습제, PE+제습제가 분말은 PE, PE+제습제 순으로 조사되었고 쌍별귀뚜라미 건조물은 PET+제습제, 내습포장제가 분말은 내습포장제만 기준치 이내로 조사되었다. 진공 포장에서 갈색거저리 건조물은 PE+제습제, 내습포장제가 분말은 PE, 내습포장제로 나타났으며 쌍별귀뚜라미 건조물은 PE+제습제, PET+제습제가 분말은 PET+제습제, 내습포장제 순으로 조사되었다. 특히, 쌍별귀뚜라미 분말은 밀봉, 진공포장 모두에서 일반세균 기준치(1,000cfu/g)가 이상을 보여 본 실험 포장재질로 는 유통이 어려운 것으로 나타났다.
Han, Weon-Cheol,Kim, Kwon-Seop,Park, Jae-Seung,Hwang, Sung-Yeoun,Moon, Hyung-Bae,Chung, Hun-Taeg,Jun, Chang-Duk The Korean Society for Integrative Biology 2001 Korean journal of biological sciences Vol.5 No.3
Ligand-receptor clustering event is the most important step in leukocyte adhesion and spreading on endothelial cells. Intercellular adhesion molecule-1 (ICAM-1) has been shown to enhance leukocyte adhesion, but the molecular event during the process of adhesion is unclear. To visualize the dynamics of ICAM-1 movement during adhesion, we have engineered stable Chinese hamster ovary cell lines expressing ICAM-1 fused to a green fluorescent protein (IC1_GFP/CHO) and examined them under the fluorescence microscopy. The transfection of IC1_GFP alone in these cells was sufficient to support the adhesion of K562 cells that express $\alpha$L$\beta$2 (LFA-1) integrin stimulated by CBR LFA-1/2 mAb. This phenomenon was mediated by ICAM-1-LFA-1 interactions, as an mAb that specifically inhibits ICAM-1-LFA-1 interaction (RRl/l) completely abolished the adhesion of LFA-1* cells to IC1_ GFP/CHO cells. We found that the characteristic of adhesion was followed almost immediately (~10 min) by the rapid accumulation of ICAM-1 on CHO cells at a tight interface between the two cells. Interestingly, ICI_GFP/CHO cells projected plasma membrane and encircled approximately half surface of LFA-1+ cells, as defined by confocal microscopy. This unusual phenomenon was also confirmed on HUVEC after adhesion of LFA-1* cells. Neither cytochalasin D nor 2,3-butanedione 2-monoxime an inhibitor of myosin light chain kinase blocked LFA-1-mediated ICAM-1 clustering, indicating that actin cytoskeleton and myosin-dependent contractility are not necessary for ICAM-1 clustering. Taken together, we suggest that leukocyte adhesion to endothelial cells induces specialized form of ICAM-1 clustering that is distinct from immunological synapse mediated by T cell interaction with antigen presenting cells.
Normally-Off Operation of AlGaN/GaN Heterojunction Field-Effect Transistor with Clamping Diode
Sang-Woo Han,Sung-Hoon Park,Hyun-Seop Kim,Jongtae Lim,Chun-Hyung Cho,Ho-Young Cha 대한전자공학회 2016 Journal of semiconductor technology and science Vol.16 No.2
This paper reports a new method to enable the normally-off operation of AlGaN/GaN heterojunction field-effect transistors (HFETs). A capacitor was connected to the gate input node of a normally-on AlGaN/GaN HFET with a Schottky gate where the Schottky gate acted as a clamping diode. The combination of the capacitor and Schottky gate functioned as a clamp circuit to downshift the input signal to enable the normally-off operation. The normally-off operation with a virtual threshold voltage of 5.3 V was successfully demonstrated with excellent dynamic switching characteristics.
Han, Mi-Na,Kim, Jeong-Ho,Lee, Sang-Kab,No, Kyong-Ok,Chae, Mun-Hui,Cho, Woo-Kyoung,Lee, Jong-Hwa,Jang, Rae-Hoon,Kim, Chang-Seop,Byeon, Hyeon-Seop The Korean Society of Veterinary Service 2020 韓國家畜衛生學會誌 Vol.43 No.2
This case describes outbreaks of acute aspergillosis in a red-crowned crane. A six-month-old, male, crane had showed clinical signs (i.e. anorexia, performance loss, ruffled feathers and drooped wings and open mouth breathing, etc.) before death. In necropsy examination, spherical to oval nodules disseminated from the respiratory tract to other organs. Those nodules were formed predominantly in air sacs, lung, peritoneum, serosa of esophagus and trachea. The nodules varied in size from 1 mm to over 1cm and the color was white to yellow. Microscopically, most of lung architecture were replaced by multiple foci which were characterized by well demarcated eosinophilic and karyorrhetic debris and surrounded by numerous Inflammatory cell. Most within necrotic center of the nodules, large numbers of fungal hyphae were present. Microbiology result indicated fungal growths on sabroud dextrose agar and bacterial growths on blood agar. Bacteria identified as E. rhusiopathiae using MALDI-TOF (microflex, BRUKER, USA) and fungi identified as A. fumigatus, A. terreus by sequencing the ITS1 and ITS4 regions. To confirm the route of infection, we checked the existence of the same pathogens in cohabitant (i.e. mother crane). The young age and weakened immunity (i.e. bacterial infection, etc.) causes fatal aspergillosis in birds.
Normally-Off Operation of AlGaN/GaN Heterojunction Field-Effect Transistor with Clamping Diode
Han, Sang-Woo,Park, Sung-Hoon,Kim, Hyun-Seop,Lim, Jongtae,Cho, Chun-Hyung,Cha, Ho-Young The Institute of Electronics and Information Engin 2016 Journal of semiconductor technology and science Vol.16 No.2
This paper reports a new method to enable the normally-off operation of AlGaN/GaN heterojunction field-effect transistors (HFETs). A capacitor was connected to the gate input node of a normally-on AlGaN/GaN HFET with a Schottky gate where the Schottky gate acted as a clamping diode. The combination of the capacitor and Schottky gate functioned as a clamp circuit to downshift the input signal to enable the normally-off operation. The normally-off operation with a virtual threshold voltage of 5.3 V was successfully demonstrated with excellent dynamic switching characteristics.