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Han Nah Cho,Eun Hye Ha 대한소아청소년정신의학회 2019 소아청소년정신의학 Vol.30 No.1
Objectives: The purpose of this study was to analyze the discriminant validity and the clinical cut off scores of the Child Behavior Checklist 1.5-5 (CBCL 1.5-5) in the diagnosis of autism spectrum disorder (ASD) and non-ASD. Methods: In total, 104 ASD and 441 non-ASD infants were included in the study. T-test, discriminant analysis, receiver operating characteristic (ROC) curve analysis, and odds ratio analysis were performed on the data. Results: The discriminant validity was confirmed by mean differences and discriminant analysis on the subscales of Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, and Total problems, along with the Diagnostic and Statistical Manual of Mental Disorders (DSM)-oriented scales between the two groups. ROC analysis showed that the following subscales significantly separated ASD from normal infants: Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Moreover, the clinical cut off score criteria adopted in the Korean-CBCL 1.5-5 were shown to be valid for the subscales Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Conclusion: The subscales of Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems significantly discriminated infants with ASD.
Han-il Lee,Tae-won Ahn,Je-Kwang Cho,Kun-seok Lee,Kyung-Suc Nah,Byeong-ha Park 한국물리학회 2005 Current Applied Physics Vol.5 No.3
A fully integrated fractional-N frequency synthesizer (FNFS) in 0.5l m SiGe BiCMOS technology is implemented. To coverwideband frequency operation, a switched capacitor bank LC tank VCO and an Adaptive Frequency Calibration (AFC) techniqueare used. A 3-bit 4th orderRD modulator is used to reduce out-of-band phase noise and to meet a frequency resolution of less than3 Hz, and agile switching time. The experimental results show)80 dBc/Hz in-band phase noise within the loop bandwidth of 25 kHzand )129 dBc/Hz out-of-band phase noise at 400 kHz-oset frequency. The fractional spurs are less than)70 dBc/Hz at 300 kHzoset frequency and the reference spur is)75 dBc/Hz. The lock time is less than 150l s. The proposed synthesizer consumes 19.5 mAfrom a single 2.8 V supply voltage and meets the requirements of GSM/GPRS/EDGE applications..
Cho, Kyung-Su,Kim, Doo-Hee,Kim, Young-Hwan,Nah, Junghyo,Kim, Han-Ki Elsevier 2017 CERAMICS INTERNATIONAL Vol.43 No.2
<P><B>Abstract</B></P> <P>We have investigated the characteristics of p-type Li-doped Cu<SUB>2</SUB>O (LCO) films grown by radio frequency magnetron sputtering to use as p-n heterojunction for flexible and semi-transparent piezoelectric nanogenerators (PENGs). Electrical, optical, morphological properties of the LCO films were examined as a function of Ar/O<SUB>2</SUB> flow ratio as well as work function. The LCO films grown at Ar/O<SUB>2</SUB> ratio of 20/4 sccm film showed a p-type behavior with resistivity of 2.12Ω-cm, mobility of 0.364cm<SUP>2</SUP>/V-s, and carrier concentration of 8.07×10<SUP>19</SUP> cm<SUP>-3</SUP>. To overcome the piezoelectric potential screening effect of conventional ZnO-based PENGs, the p-type LCO layer was employed. Due to the enhanced piezoelectric potential coupled with the reduced total capacitance, the PENG with a p-LCO/n-ZnO heterojunction demonstrates the much higher output power up to ~52 μW than PENG only with ZnO layer (7 μW). The improved output power of PENGs indicates that sputtering of the p-type LCO layer on the n-type ZnO is the effective method to overcome the limit of the ZnO-based PENGs.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
INTERNATIONAL COLLABORATION FOR SILICON CARBIDE MIRROR POLISHING AND DEVELOPMENT
HAN, JEONG-YEOL,CHO, MYUNG,POCZULP, GARY,NAH, JAKYUNG,SEO, HYUN-JOO,KIM, KYUNG-HWAN,TAHK, KYUNG-MO,KIM, DONG-KYUN,KIM, JINHO,SEO, MINHO,LEE, JONGGUN,HAN, SUNG-YEOP The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
For research and development of Silicon Carbide (SiC) mirrors, the Korea Astronomy and Space Science Institute (KASI) and National Optical Astronomy Observatory (NOAO) have agreed to cooperate and share on polishing and measuring facilities, experience and human resources for two years (2014-2015). The main goals of the SiC mirror polishing are to achieve optical surface figures of less than 20 nm rms and optical surface roughness of less than 2 nm rms. In addition, Green Optics Co., Ltd (GO) has been interested in the SiC polishing and joined the partnership with KASI. KASI will be involved in the development of the SiC polishing and the optical surface measurement using three different kinds of SiC materials and manufacturing processes (POCO$^{TM}$, CoorsTek$^{TM}$ and SSG$^{TM}$ corporations) provided by NOAO. GO will polish the SiC substrate within requirements. Additionally, the requirements of the optical surface imperfections are given as: less than 40 um scratch and 500 um dig. In this paper, we introduce the international collaboration and interim results for SiC mirror polishing and development.
Han Joon Bae,Yun-Kyeong Cho,Hyoung-Seob Park,Hyuck-Jun Yoon,Hyungseop Kim,Seongwook Han,Seung-Ho Hur,Yoon-Nyun Kim,Kwon-Bae Kim,Jae-Kean Ryu,Deug Young Nah,Chang-Wook Nam 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.2
Background/Aims: To date, prospective data are limited on efficacy and safety profiles of statin therapy in Korean hypercholesterolemic patients. Hence, the aim of this study was to evaluate the practice patterns of statin therapy and its efficacy and safety through the prospective Daegu and Gyeongbuk statin registry. Methods: Statin naïve patients who were prescribed statins according to the criteria of Korean Guidelines for Management of Dyslipidemia were enrolled. Clinical and laboratory evaluations were performed at baseline and at week 8, where the efficacy was assessed with the same guidelines. Results: Of 908 patients, atorvastatin and rosuvastatin were most frequently prescribed statins (63.1% and 29.3%, respectively). High intensity statins (atorvastatin 40 mg or rosuvastatin 20 mg) were prescribed in 24.7% of all patients and in 79.5% of high and very high risk groups. The total and low density lipoprotein (LDL) cholesterol levels decreased from 203.7 ± 43.0 to 140.6 ± 28.6 mg/dL and 134.4 ± 35.7 to 79.5 ± 21.3 mg/dL, respectively. The achievement rate of the LDL target goal was 98.6% in low risk, 95.0% in moderate risk, 88.1% in high risk, and 42.1% in very high risk patients (59.7% in overall). There was no significant difference in the efficacy between atorvastatin and rosuvastatin. Adverse events were observed in 12.0% of patients and led to 1.4% of treatment cessation. Conclusions: The efficacy of the usual starting dose of statins in daily practice was relatively insufficient for Korean hypercholesterolemic patients with high or very high risks. Short-term adverse events of statin therapy were not common in Korean patients with a low discontinuation rate.
Nah, Ja-Kyoung,Chae, Jong-Chul,Park, Young-Deuk,Park, Hyung-Min,Jang, Bi-Ho,Ahn, Kwang-Su,Yang, Hee-Su,Cho, Kyung-Suk,Kim, Yeon-Han,Kim, Kwang-Dong,Cao, Wenda,Gorceix, Nicolas,Goode, Philip. R. 한국천문학회 2011 天文學論叢 Vol.26 No.1
KASI and Seoul National University developed the Fast Imaging Solar Spectrograph (FISS) as one of major scientific instruments for the 1.6 m New Solar Telescope (NST) and installed it in the Coude room of the NST at Big Bear Solar Observatory (BBSO) in May, 2010. The major objective of the FISS is to study the fine-scale structures and dynamics of plasma in the photosphere and chromosphere. To achieve it, the FISS is required to take data with a spectral resolution higher than $10^5$ at the spectrograph mode and a temporal resolution less than 10 seconds at the imaging mode. The FISS is a spectrograph using Echelle grating and has characteristics that can observe dual bands (H${\alpha}$ and CaII 8542) simultaneously and perform fast imaging using fast raster scan and two fast CCD cameras. In this paper, we introduce briefly the whole process of FISS development from the requirement analysis to the first observations.
( Han Nah Seok ),( Eun Young Lee ),( Eun Yeong Choe ),( Woo In Yang ),( Joo Young Kim ),( Dong Yeob Shin ),( Ho Jin Cho ),( Tae Sung Kim ),( Mi Jin Yun ),( Jong Doo Lee ),( Eun Jig Lee ),( Sung Kil Li 대한내과학회 2013 The Korean Journal of Internal Medicine Vol.28 No.1
Background/Aims: Although magnetic resonance imaging (MRI) is a good visual modality for the evaluation of pituitary lesions, it has limited value in the diagnosis of mixed nodules and some cystic lesions. We evaluated the usefulness of 18F-fluorodeoxyglucose positron emission tomography (FDG PET) for patients with pituitary lesions. Methods: 18F-FDG PET and MRI were performed simultaneously in 32 consecutive patients with pituitary lesions. The relationships between FDG uptake patterns in PET and MRI findings were analyzed. Results: Of 24 patients with piuitary adenomas, 19 (79.2%) showed increased uptake of 18F-FDG in the pituitary gland on PET scans. All patients with pituitary macroadenomas showed increased 18F-FDG uptake on PET scans. Meanwhile, only five (50%) of the 10 patients with pituitary microadenomas showed positive PET scans. Interestingly, of two patients with no abnormal MRI findings, one showed increased 18F-FDG uptake on PET. For positive 18F-FDG uptake, maximum standardized uptake values (SUVmax) > 2.4 had 94.7% sensitivity and 100% specificity. In addition, SUVmax increased in proportion to the size of pituitary adenomas. Most cystic lesions did not show 18F-FDG uptake on PET scans. Consclusions: About 80% of pituitary adenomas showed positivity on PET scans, and SUVmax was related to the size of the adenomas. PET may be used as an ancillary tool for detection and differentiation of pituitary lesions.
( Yun Nah Lee ),( Jong Ho Moon ),( Hyun Jong Choi ),( Hee Jae Jung ),( Moon Han Choi ),( Tae Hoon Lee ),( Sang Woo Cha ),( Young Deok Cho ),( Sang Heum Park ),( Sun Joo Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background and Aims: Direct peroral cholangioscopy (DPOC) using an ultra-slim endoscope is one of possible POCs by single operator to provide direct visualization of the bile duct. However, currently available accessory for DPOC is limited for the effective procedure. The aim of this study was to evaluate the feasibility and success rate of intraductal guided DPOC with a novel access balloon catheter for cholangioscopy to maintain access. Patients and Methods: From January 2014 to July 2014, 36 patients with biliary obstruction underwent DPOC. Biliary obstruction on intra-pancreatic segment was excluded. All patients underwent an endoscopic sphincterotomy and/or papillary balloon dilation. Intraductal balloon guided DPOC using modifi ed two lumens 5F access balloon catheter for cholangioscopy (MTW Endoskopie, Wesel, Germany) was performed. The success of cholangioscopy was defi ned as advance of the endoscope into the distal margin of obstruction. Results: The success rate of intraductal balloon guided direct POC using access balloon catheter was 97.2% (35/36 patients). 26 patients were malignant, and 5 patients was benign biliary stricture, 4 patients showed impacted stone. DPOC was failed in one patient with benign stricture. Interventional procedures including forceps biopsy or lithotripsy were performed successfully, if needed. Procedure related complication was not occurred in all patients except one self-limited cholangitis. Conclusions: Modifi ed access balloon catheter for cholangioscopy seems to facilitate performing intraductal balloon guided DPOC for the direct visual examination of bile duct in patients with biliary obstruction.
Lee, Sol,Cho, A Ra,Park, Daehoon,Kim, Jae Kyeom,Han, Kyung Seok,Yoon, Ick-Jae,Lee, Min Hyung,Nah, Junghyo American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.3
<P>Ultrafine particulate matters (PMs) are an imminent threat to the human respiratory system, as their sizes are comparable to and even smaller than human tissues. To cope with this situation, researchers have developed and commercialized various personal dust proof masks. However, because of the relatively thick filter membrane to guarantee filtering efficiency, a huge pressure drop across the active filter layer is inevitable and breathing through it becomes uncomfortable. In this work, we investigated the performance of electrospun polybenzimidazole (PBI) nanofiber membrane filters that can potentially be used for dust proof masks or other high-performance filters. Thanks to its high dipole moment (6.12) as confirmed by density functional theory (DFT) calculation, the surface potential of the PBI nanofiber air filter, measured by KPFM, was higher than that of other commercially available mask filters. The filter developed in this work provides high PM filtering efficiency of ∼98.5% at much reduced pressure drop (130 Pa) in comparison to those used in commercially available masks (386 Pa) with similar filtering efficiencies. Consequently, an approximately 3-fold higher quality factor (∼0.032), evaluated for PM<SUB>2.5</SUB>, in comparison to that of commercial ones (∼0.011) was achieved by using PBI nanofiber. Furthermore, we developed a cleaning method effective for the filter contaminated by both inorganic and organic PMs. Even after several cycles of cleaning, the PBI filter membrane demonstrated negligible damage and retained its original performance because of its mechanical, thermal, and chemical durability.</P> [FIG OMISSION]</BR>