A New BISON-like Construction Block Cipher: DBISON

Haixia Zhao,Yongzhuang Wei,Zhenghong Liu 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.5

At EUROCRYPT 2019, a new block cipher algorithm called BISON was proposed by Canteaut et al. which uses a novel structure named as Whitened Swap−Or−Not (WSN). Unlike the traditional wide trail strategy, the differential and linear properties of this algorithm can be easily determined. However, the encryption speed of the BISON algorithm is quite low due to a large number of iterative rounds needed to ensure certain security margins. Commonly, denoting by n is the data block length, this design requires 3n encryption rounds. Moreover, the block size n of BISON is always odd, which is not convenient for operations performed on a byte level. In order to overcome these issues, we propose a new block cipher, named DBISON, which more efficiently employs the ideas of double layers typical to the BISON-like construction. More precisely, DBISON divides the input into two parts of size n/2 bits and performs the round computations in parallel, which leads to an increased encryption speed. In particular, the data block length n of DBISON can be even, which gives certain additional implementation benefits over BISON. Furthermore, the resistance of DBISON against differential and linear attacks is also investigated. It is shown the maximal differential probability (MDP) is 1/2n-1 for n encryption rounds and that the maximal linear probability (MLP) is strictly less than 1/2n-1 when (n/2+3) iterative encryption rounds are used. These estimates are very close to the ideal values when n is close to 256.

Rheinic acid ameliorates radiation‑induced acute enteritis in rats through PPAR‑γ/NF‑κB

Haixia Sha,Yu Gu,Weixing Shen,Li Zhang,Fei Qian,Yudong Zhao,Haixiao Li,Ting Zhang,Weimin Lu 한국유전학회 2019 Genes & Genomics Vol.41 No.8

Background Acute radiation enteritis (ARE), a common complication of intestinal caused by abdominal and pelvic radiation therapy. Rheinic acid is a major active ingredient derived from Rhubarb. Rhubarb could suppress inflammation, tumor, fibrosis oxidative damage. However, RA as the main active component and extract monomer of Rhubarb, the pharmacological activity and the underlying molecular mechanism on various diseases has not yet been revealed. Objective To determine the potential role of rheinic acid (RA) in ameliorating inflammation of rats with acute radiation enteritis (ARE), and explore the underlying mechanism. Methods ARE rat model was established by irradiated with single-dose 10 Gy X-rays at a rate of 0.62 Gy/min to the abdomen. The rats were executed after orally administered with Rheinic acid 7 days and used in the subsequent experiments. Body weight, fecal characteristics and bloody of rats were used to assess the disease activity index. Histological analysis of the jejunum and colon were evaluated using H&E staining. The pro-inflammatory cytokines levels were measured by immunohistochemistry and ELISA. The levels of nitric oxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione (GSH) were also determined. The mRNA and protein expression were examined by real-time polymerase chain reaction (qRT-PCR) and western blot, respectively. Results Rheinic acid promoted intestinal functional recovery, and ameliorated intestinal damage and bloody stool in ARE rats. Rheinic acid strongly decreased the levels of tumor necrosis factor-α, interleukin-1, interleukin-6, NO, and MDA, whereas increased levels of anti-oxidants, SOD and GSH. Moreover, the expression of apoptosis-related proteins, cleaved caspase-3 and cleaved poly (ADP-ribose) polymerase (PARP), were decreased with RA treatment. Further study indicated that PPAR-γ was activated and thereby NF-κB and p38 MAPK signaling pathway were suppressed after rheinic acid treatment. Conclusion Rheinic acid could ameliorate acute radiation enteritis and the underlying molecular mechanism is, at least partially, through PPAR-γ/NF-κB and p38 MAPK/JNK pathways.

EGR1 promotes stemness and predicts a poor outcome of uterine cervical cancer by inducing SOX9 expression

Juanhong Zhao,Haixia Li,Miao Yuan 한국유전학회 2021 Genes & Genomics Vol.43 No.5

Background Early growth response-1 (EGR1) is a transcription factor involved in the progression of several cancer types. However, the expression and clinical signifcance of EGR1 in uterine cervical cancer (CC) have not been elucidated. Objective To investigate the expression, clinical signifcance and prognostic value of EGR1 in CC. Methods The expression of EGR1 was detected in 13 CCs and paired adjacent tissues with qRT-PCR and in 144 CC tissues with immunohistochemistry (IHC). The IHC scores were used to divide the patients into subsets with low and high EGR1 expression. The correlations between the EGR1 expression and clinicopathological factors were analyzed with the chi-square test, and the prognostic signifcance of EGR1 expression was evaluated with univariate and multivariate analyses. The functions of EGR1 in the proliferation, invasion and stemness of CC cells were investigated, and the molecular mechanism was assessed by in vitro experiments. Results High expression of EGR1 was signifcantly associated with low survival rates of CC. EGR1 is an independent prognostic biomarker of CC, and its high expression predicted a poor outcome. EGR1 facilitated stemness and thus promoted proliferation and invasion of CC cells. SOX9 played an essential role in the EGR1-induced progression of CC cells. Conclusions EGR1 is an independent prognostic biomarker of CC. High EGR1 expression promoted proliferation, invasion and stemness by increasing SOX9 expression in CC cells. Our results suggested that the EGR1-SOX9 axis may be a potential drug target and that blocking the EGR1-SOX9 axis may be a possible approach to treating CC.

Isolation, identification and characterization of a novel elastase from Chryseobacterium indologenes

Lei, Yunlong,Zhao, Peipei,Li, Chenglei,Zhao, Haixia,Shan, Zhi,Wu, Qi The Korean Society for Applied Biological Chemistr 2018 Applied Biological Chemistry (Appl Biol Chem) Vol.61 No.3

Elastase is a type of protease that specifically degrades elastin. It has broad application prospects in medicine, food industry, and daily-use chemical industry. In this study, we isolated a bacterial strain WZE87 with high elastin-hydrolysis activity, which was identified as Chryseobacterium indologenes based on morphology, physiological and biochemical characteristics, and 16S rDNA sequence analysis. The elastase produced by this strain was purified by three steps: ammonium sulfate precipitation, Q-Sepharose fast-flow anion-exchange chromatography, and Sephadex G-75 gel-filtration chromatography. The purified elastase was 2376.5 U/mg in activity (a 8.3-fold increase in specific activity), and the recovery was 5.8%. Its molecular mass was estimated to be 26 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. This enzyme was stable in the pH range of 5.0-10.5 at $37^{\circ}C$. The optimal temperature and pH were $37^{\circ}C$ and 7.5, respectively. The activity of this elastase was found to decrease when the temperature was higher than $50^{\circ}C$. The activity was also inhibited by $Zn^{2+}$, $Fe^{2+}$, $Fe^{3+}$, and $Mn^{2+}$ ions. The specific hydrolytic ability of this enzyme was similar to that of papain on substrates like gelatin, casein, soybean-isolated protein and bovine hemoglobin. However, this elastase preferentially hydrolyzed elastin in a protein mixture because of its specific adsorption. Considering its promising properties, this protease may be considered a potential candidate for applications in related industries.

Annealing Effect on the Electron Spin Dynamics in Heavily Mn-doped (Ga,Mn)As

Han Yue,Lin Chen,Haixia Gao,Jianhua Zhao,Xinhui Zhang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.10

A temperature- and photo-excitation-density-dependent electron spin dephasing process has beenstudied by time-resolved magneto-optical Kerr effect (TR-MOKE) measurements for heavily-doped(Ga,Mn)As after appropriate annealing treatment. Unlike the as-grown (Ga,Mn)As in which sdscattering is dominant for spin dephasing at low temperature, the exchange scattering inducedby Mn ions is efficiently suppressed after annealing. For annealed (Ga,Mn)As, the p-d exchangecoupling proves to be important for the electron spin dephasing process. Moreover, the Coulombscattering arising from the weakly-localized holes and Mn impurities is revealed to play an importantrole in the electron spin dephasing after annealing. Our results demonstrate that the impurityinduceddisorder plays a significant role in the electron spin-dephasing process in (Ga,Mn)As whenMn is over doped by as much as 15%, which is a critical issue that needs to be considered to achievehigh-quality (Ga,Mn)As thin films with a higher Curie temperature TC and better functionality.

Isolation, identification and characterization of a novel elastase from Chryseobacterium indologenes

Yunlong Lei,Peipei Zhao,Chenglei Li,Haixia Zhao,Zhi Shan,Qi Wu 한국응용생명화학회 2018 Applied Biological Chemistry (Appl Biol Chem) Vol.61 No.3

Elastase is a type of protease that specifically degrades elastin. It has broad application prospects in medicine, food industry, and daily-use chemical industry. In this study, we isolated a bacterial strain WZE87 with high elastin-hydrolysis activity, which was identified as Chryseobacterium indologenes based on morphology, physiological and biochemical characteristics, and 16S rDNA sequence analysis. The elastase produced by this strain was purified by three steps: ammonium sulfate precipitation, Q-Sepharose fast-flow anion-exchange chromatography, and Sephadex G-75 gel-filtration chromatography. The purified elastase was 2376.5 U/mg in activity (a 8.3-fold increase in specific activity), and the recovery was 5.8%. Its molecular mass was estimated to be 26 kDa by sodium dodecyl sulfate–polyacrylamide gel electrophoresis. This enzyme was stable in the pH range of 5.0–10.5 at 37 C. The optimal temperature and pH were 37 C and 7.5, respectively. The activity of this elastase was found to decrease when the temperature was higher than 50 C. The activity was also inhibited by Zn2?, Fe2?, Fe3?, and Mn2? ions. The specific hydrolytic ability of this enzyme was similar to that of papain on substrates like gelatin, casein, soybean-isolated protein and bovine hemoglobin. However, this elastase preferentially hydrolyzed elastin in a protein mixture because of its specific adsorption. Considering its promising properties, this protease may be considered a potential candidate for applications in related industries.

A Research of Sensors Complementary for the RFID Wireless Network Based on the Variable Coverage Radius

Hongzhi Wang,Yang Zhao,Haixia Zhou 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.12

In order to solve the problems of sensors complementary, algorithm sensors complementary for the RFID wireless network is proposed in this paper. Based upon the fundamental definitions about the probabilistic events and the data generated by the particle filtering algorithm, the paper considers the factors of the number of locations covered and the probability the object appears. In view of the definition of the covering variability and the cover ratio, 5kinds of RFID sensors covering radius are considered. Finally, the experiment is carried out in order to improve the algorithm’s availability and effectiveness.

Nonisothermal Decomposition Reaction Kinetics, Specific Heat Capacity, Thermodynamic Properties and Adiabatic Time-to-explosion of 4-Amino-1,2,4-triazole Copper Complex

Ren, Yinghui,Li, Dan,Yi, Jianhua,Zhao, Fengqi,Ma, Haixia,Xu, Kangzhen,Song, Jirong Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.7

4-Amino-1,2,4-triazole copper complex (4-ATzCu) was synthesized, and its thermal behaviors, nonisothermal decomposition reaction kinetics were studied by DSC and TG-DTG techniques. The thermal decomposition reaction kinetic equation was obtained as: $d\alpha$ / dt =$10^{22.01}$ (1-$\alpha$)[-ln(1-$\alpha$)]$^{1/3}$ exp($-2.75\times10^4$ /T). The standard mole specific heat capacity of the complex was determined and the standard molar heat capacity is 305.66 $J{\cdot}mol^{-1}{\cdot}K^{-1}$ at 298.15 K. The entropy of activation $({\Delta}S^{\neq})$, enthalpy of activation $({\Delta}H^{\neq})$, and Gibbs free energy of activation $({\Delta}G^{\neq})$ are calculated as 171.88 $J{\cdot}mol^{-1}{\cdot}K^{-1}$ 225.81 $kJ{\cdot}mol^{-1}$ and 141.18 $kJ{\cdot}mol^{-1}$, and the adiabatic time-to-explosion of the complex was obtained as 389.20 s.

Nonisothermal Decomposition Reaction Kinetics, Specific Heat Capacity, Thermodynamic Properties and Adiabatic Time-to-explosion of 4-Amino-1,2,4-triazole Copper Complex

Yinghui Ren,Dan Li,Jianhua Yi,Fengqi Zhao,Haixia Ma,Kangzhen Xu,Jirong Song 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.7

4-Amino-1,2,4-triazole copper complex (4-ATzCu) was synthesized, and its thermal behaviors, nonisothermal decomposition reaction kinetics were studied by DSC and TG-DTG techniques. The thermal decomposition reaction kinetic equation was obtained as: dα / dt =1022.01 (1−α )[−ln(1−α )]1/3 exp(−2.75×104 /T) . The standard mole specific heat capacity of the complex was determined and the standard molar heat capacity is 305.66 J·mol‒1·K‒1 at 298.15 K. The entropy of activation ( ΔS ≠ ), enthalpy of activation (ΔH ≠), and Gibbs free energy of activation ( ΔG≠) are calculated as 171.88 J·mol‒1·K‒1, 225.81 kJ·mol‒1 and 141.18 kJ·mol‒1, and the adiabatic time-to-explosion of the complex was obtained as 389.20 s.

A Novel Data Filling Algorithm for Incomplete Information System Based on Valued Limited Tolerance Relation

Xiuling Bai,Mingchuan Zhang,Qingtao Wu,Ruijuan Zheng,Haixia Zhao,Wangyang Wei 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.6

Due to various reasons, there are generally missing data in datasets. Usually the missing data in these incomplete datasets need to be filled. In this paper, the drawbacks of some existing data filling approaches for incomplete information systems are analyzed based on Rough Set theory. Several similarity relation models are discussed and the Valued Limited Tolerance Relation model is proposed. A data filling algorithm based on the Valued Limited Tolerance Relation model is put forward. This approach makes full use of the similarity of objects and selects the object which is the most similar to the incomplete object. More missing data can be filled scientifically. The experimental results show that this approach is effective.