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      • KCI등재

        느릅나무 근피 드레싱이 쥐에 유발된 화상의 회복에 미치는 효과

        나연경,홍해숙 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.1

        Purpose : The purpose of this study is to compare the effect of Ulmus(root-bark) dressing with vaseline gauze dressing on burn wound(third degree) in rats. Method : Ten male Sprague-Dawley rats were used in the study. The rats were anesthetized with Ketamine 100mg/kg. Burn wounds were made for each animal by specially designed apparatus. Ulmus dressing was applied once a day for 4 weeks in the experimental group(n=5), vaseline gauze dressing in the control group(n=5). The wounds were photographed and excised. Result : After 10 days of dressing, size of burn wounds of Ulmus dressing group decreased significantly compared to that of vaseline gauze dressing group. After 10 days of dressing, degree of inflammatory infiltration was shown lower in Ulmus dressing than in vaseline gauze group. There was no significant difference after dressing at day of 19 and 27 in degree of inflammatory infiltration.

      • 식이 ω3 지방 섭취가 발달과정의 흰쥐 뇌지질에 미치는 영향

        나혜경,조성희 대구효성가톨릭대학교 응용과학연구소 1993 응용과학연구논문집 Vol.2 No.-

        식이 ω3지방 섭취가 발달과정의 뇌지질 지방산 축적에 미치는 영향을 조사하기 위해 ω3지방산이 다량 함유된 고등어유, 들깨유와 비교군으로 콩기름, 쇠기름, 채종유의 5종류의 식이지방을 식이중에 10%로 제조하여 섭취게 한 후 태아, 수유, 이유기를 거치는 동안의 뇌지질 지방산 구성변화를 추적하고 cholesterol 함량과 acetylcholinesterase활성을 측정하였다. 그 결과 뇌조직 지방산중 포화와 불포화지방산은 모두 지속적으로 축적되며 C18:2(ω6)나 C18:3(ω3)같은 short-chain 전구체의 비율은 상대적으로 감소되는 반면 그 long chain유도체의 비율은 증가하여 정량적으로 축적되었다. 특히 C22:6(ω3)의 축적이 타지방산에 비해 많으며 고등어유군에서 계속 높은 경향으로 이는 C20-22 (ω3)지방산의 incoproation율이 타 식이지방의 주요지방산보다 뚜렷이 높음을 뜻한다. 반면 들깨유군에서는 C20:5(ω3)의 elongation은 활발하게 C22:6(ω3)까지의 elongation은 원할치 않다는 것을 나타낸다. Cholesterol함량과 acetycholinesterase 성분은 전 발달과정 동안에 증가하는 경향이었으며 cholesterol 함량은 고등어유군과 쇠기름군에서 높았고 acetylcholinesterase 활성은 각 군간에 큰 차이가 없었다. Male nad female Sprague-Dawley rats(~70g) were fed five different diets containing various dietary fats and at the level of 10%(w/w). Dietary fats used were mackerel oil(MO), perilla oil(PO), soybean oil(SO), repeseed oil(RO), and beef tallow(BT). After 34days of feeding experimental diets, when rats weighed about 200g, male and female rats were mated. Experimental diets were continued throughout pregnancy and lactation of female rats and weanling period of the offsprings. Fatty acid composition and cholesterol content of brain lipid were measured as well as activities of acetylcholinesterase during fetal(day-10, -5), neonate(day 0) and postnatal (day 17, 26, 39) periods. Both saturated and unsaturated fatty acids of brain lipid were progressively elongated from fetal(day-10) to postnatal(day 39). Levels of ω3, ω6 and ω9 fatty acid were notably high in MO, SO, and BT group respectively. In PO group, the level of C20:5(3ω) was higher while the level of C22:6(ω3) was almost the same, as other groups, suggesting that elongation of C18:3(ω3) to C20:5(ω3 is active but not to C22:6(ω3). On the other hand, C22:6(ω3) in MO was very well incorporated in to brain lipid as such. Cholesterol content and acetylcholinesterase activity were increased during the whole period of development. Cholesterol content was highest in MO group. However, acetylcholinesterase activities did not between groups.

      • KCI등재후보

        천연염색 의류에 대한 소비자 반응 및 소비자 특성

        홍나영,유혜경,이주현,석혜정,신혜성,김찬주 服飾文化學會 2003 服飾文化硏究 Vol.11 No.3

        The main purpose of this exploratory research was to examine the characteristics of consumers who patronize natural-dyed clothes and their perceptions regarding natural-dyed clothes. Thirty three participants who have worn natural-dyed clothes were interviewed for the study. They were asked about styles and price of natural-dyed clothes they owned, their evaluation on them, and the lifestyles of themselves. Existence of subculture among the interviewes and its characteristics were also probed. The results indicated that natural-dyed clothes are relatively high-priced, mostly of modified hanbok style, and became popular in recent years. Interviewees frequently mentioned uniqueness and comfort as the main benefits of natural-dyed clothes, and expressed dissatisfaction regarding color fastness, easy care and problem of coordination. The consumers of natural-dyed clothes appeared to have strong preferences for environment conservation and Korean traditional culture. They also seemed to form a subcultural group who have commonality in their involvement in Korean cultural activities, mainly tea ceremony.

      • KCI등재

        일 도시 고등학생의 음주동기와 음주문제

        강혜영,신경은,장현지,나영화,조은희 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.2

        Purpose : The purpose of this study was to investigate drinking motives and the drinking-related problems of Korean high school students at a city in Jeonbuk province. Methods : There were 657 students from two academic and two vocational high schools at J city in Jeonbuk province. The sample was collected using a stratified sampling method and the data was collected from June 30th to July 16th 2003. The study instrument used to examine drinking motive was a 20.item summated scale (Cronbach's α = .95) and for drinking-related problems was an 18 item summated scale (Cronbach's α = .91). The data was analyzed using SPSS/PC+ by percentage, χ2.test, t-test and correlations. Results : 1. Drinking experience: Among the high school students, 74.3% of them had drinking episodes. Female students started drinking later (χ2 = 12.857, p = .002) and had more drinking friends (χ2 = 7.785, p = .020) than males. Vocational school students drank more frequently (χ2 = 32.138, p = .001), had more heavy drinking episodes (χ2 = 40.370, p = .001). 2. Drinking motives & Drinking-related problems: The mean score of drinking motives was 31.2 ± 11.12 out of 80 and that of drinking-related problems was 21.8 ± 5.85 out of 72 points. Neither score were stronger was significantly different according to gender and grade. On the other hand, both drinking motives (t = .4.077, p = .001) and drinking-related problems (t = .3.423, p = .001) were stronger in vocational school students than in academic school students. The correlation between drinking-related characteristics and problems were weak (from r = .286 to r = .520) but the correlation within the subcategories of drinking motives was high such as between enhancement and coping (r = .822) and enhancement and social motives (r = .822). Conclusion : The majority of Korean high school students start to drink during their junior high school days. Drinking motives and drinking-related problems were not serious but the drinking motives and the drinking-related problems are stronger among vocational school students. As a result, school-based health education and counseling programs should focus on solving drinking motives than on drinking-related problems.

      • KCI등재

        응급실에 내원한 약물중독환자의 지역별 비교분석

        임근우,박일영,유승진,나병호,오동렬,전해명,황주일,김세경 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

        We reviewed retrospectively 230 patients who came to emergency room of Kang Nam St. Mary's Hospital and Uijongbu St. Mary's Hospital between 1. January and 31. December 1994. We classified them according to their age, sex, a sort of drug, the cause of poisoning, prehospital care, time-lapse to arrive at hospital after poisoning, psychiatric problem the status of patients. *We conclude as follows; 1. The male to female ratio was totally 1 : 1.98, 1 : 1.24 in a urban area, 1 : 2.43 in a rural area. 2. On age of the patients in this study, the peake incidence was between 20 and 39(55.2%). 3. On seasonal prevalence, the poisoning was most common in summer and spring, in urban area(35.7%) and rural area(37.0%) respectively. 4. The common drug were as follow; Doxylamine, Organophosphate, Acetaminophen in urban area, Paraquat, Organophospate, Doxylamine in rural area 5. The percentage of suicidal attempt were 81.8% and 87.7% in urban area and rural area respectively. 6. The poisoning patients had psychatric problem in 19.4% and 24.6%, in urban area and rural area respectively. 7. Before arrival to emergency room, 27.7% of patient was done prehospital care in rural area. 8. On arrival to emergency room, 95.1% and 73.8% of patients show stable vital sign in urban area and rural area respectively.

      • Effect of Flap Removal in Myopic Epi-LASIK Surgery on Visual Rehabilitation and Postoperative Pain: A Prospective Intraindividual Study

        Na, Kyung-Sun,Lee, Kyung-Min,Park, Shin-Hae,Lee, Hyun-Soo,Joo, Choun-Ki S. Karger AG 2010 Ophthalmologica Vol.224 No.5

        <P><I>Purpose:</I> A prospective intraindividual study to evaluate the effect of flap removal in myopic epi-LASIK surgery on visual rehabilitation and postoperative pain. <I>Methods:</I> Ninety eyes of 45 patients were treated for myopia with epi-LASIK. In each patient, the epithelial flap was repositioned in one eye after epi-LASIK (group 1) while the flap was removed in the other (group 2). Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE) refraction, postoperative pain and corneal haze were examined for 6 months after surgery in both groups. <I>Results:</I> Group 2 had a better UCVA at 4 days and BCVA at 1 week after surgery (p = 0.001, p = 0.043) than group 1. No significant differences were observed between the two groups in terms of UCVA, BCVA, or SE refraction at 1 week and 1, 2 and 6 months. Postoperative pain scores were similar for both groups. In group 2, severe pain (pain level ≥6) was relatively less than in group 1 at 2 h and 12 h after surgery. Corneal haze levels in both groups were not different. <I>Conclusions:</I> Epi-LASIK surgery with flap removal was found to significantly promote re-epithelialization and visual recovery during the early postoperative period. It was also found to be more predictable and less painful than epi-LASIK surgery.</P><P>Copyright © 2010 S. Karger AG, Basel</P>

      • KCI등재
      • A Case of Spontaneous Bladder Rupture Mimicking Diabetic Nephropathy in a Patient with Type 2 Diabetes Mellitus

        Hae-Kyung Yang,장상아,Na-Young Kim,Soo Jeong Yeom,김지현,Jung Min Lee 고신대학교(의대) 고신대학교 의과대학 학술지 2012 고신대학교 의과대학 학술지 Vol.27 No.2

        Spontaneous rupture of the urinary bladder is a rare clinical entity, with the incidence reported as 1 in 126,000 hospital admissions. It is often associated with malignancy, inflammatory lesions, irradiation, calculus, diverticulum, binge alcohol drinking, continuous bladder irrigation, and neurogenic bladder. In rare instances, bladder rupture occurs without obvious causes. This rare clinical condition is difficult to diagnose because of vague symptoms. High index of suspicion is needed as the mortality rate is high if untreated. A 37-year-old woman with uncontrolled type 2 diabetes, was admitted to the emergency room complaining of progressive abdominal distension and discomfort. She had a past history of tubo-ovarian and bladder abscess, and had undergone multiple surgical operations. From ascites fluid study, she was diagnosed as spontaneous bladder rupture. A transurethral catheter was inserted and the symptoms and signs resolved. Bladder rupture, mimicking acute kidney injury of diabetic nephropathy was disclosed without surgery.

      • KCI등재

        Hypermethylation of Growth Arrest DNA-Damage-Inducible Gene 45 in Non-Small Cell Lung Cancer and Its Relationship with Clinicopathologic Features

        Na, Yeon-Kyung,Lee, Su-Man,Hong, Hae-Sook,Kim, Jae-Bum,Park, Jae-Yong,Kim, Dong-Sun Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.1

        The growth arrest DNA-damage-inducible protein 45 (GADD45) can serve as a key coordinator of the stress response by regulating cell cycle progression, genomic stability, DNA repair, and other stress-related responses. Although deregulation of GADD45 expression has been reported in several types of human tumors, its role in lung cancer is still unknown. DNA hypermethylation of promoter CpG islands is known to be a major mechanism for epigenetic inactivation of tumor suppressor genes. We investigated the methylation status of GADD45 family genes (GADD45A, B, and G) in 139 patients with non-small cell lung cancer (NSCLC) using methylation-specific PCR (MSP) and correlated the results with clinicopathologic features of the patients. Methylation frequencies in tumors were 1.4% for GADD45A, 7.2% for GADD45B, and 31.6% for GADD45G. RT-PCR and MSP analysis showed that promoter methylation of the GADD45G gene resulted in down-regulation of its mRNA expression. GADD45G methylation was significantly more frequent in female patients than male patients (P = 0.035). This finding suggests that methylation-associated down-regulation of the GADD45G gene may be involved in lung tumorigenesis.

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