김구림의 아방가르드에 대한 고찰 -〈매스미디어의 유물>, 제4집단 이전의 해프닝과 제4집단의 활동을 중심으로-

이은희 ( Lee¸ Eunhee ) 한국기초조형학회 2021 기초조형학연구 Vol.22 No.5

본 연구는 한국 현대미술에 있어 실험적 예술을 실천한 김구림의 아방가르드에 대한 의의를 고찰하는 것을 목표로 한다. 연구 대상은 1969년부터 1970년까지 김구림이 참여한 메일 아트, 해프닝과 제4집단의 활동이다. 이를 위해 김구림이 동료 작가들과 함께 진행한 <매스미디어의 유물>과 <콘돔과 카바마인>, <육교 위에서의 해프닝>을 각각 분석하고 제4집단의 새로운 예술을 향한 시도를 살펴볼 것이다. <매스미디어의 유물>은 편지라는 새로운 매체를 한국 미술에 도입함과 동시에 편지의 수신자들을 작품의 창작 및 가치 생성의 참여자로 끌어들였다. <콘돔과 카바마인>은 예술을 감상하는 새로운 방법을 제시하며 기존의 사물과 인식에 대한 고정 관념을 타파하고자 하였다. 육교에 풍선 백여개를 매달아 행인들이 그 사이를 지나가게 한 <육교 위에서의 해프닝> 역시 사람들의 참여를 필연적으로 요구한 새로운 시도의 작업이었다. 작품의 생산과 수용에 있어서 작가와 관객의 경계를 무너뜨렸던 이러한 김구림의 작업은 이후 제4집단의 활동을 통해 문화 비판적 예술을 실현하는 것으로 확대된다. 제4집단은 인간 본연의 해방을 주장하고 기성의 문화예술을 비판함으로써 보다 개념적인 예술의 실천으로 나아갔다. 이와 같은 김구림의 작업들은 아방가르드라는 개념으로 묶일 수 있다. 하지만 이 지점에서 김구림의 작업에 있어 전위란 무엇인지에 대한 질문이 남게 된다. 본 연구는 그 해답을 새로운 예술을 지향하였던 작가의 시도 그 자체에서 찾고, 이를 레나토 포지올리의 아방가르드 이론을 통해 부연할 것이다. 포지올리가 말한 것처럼 아방가르드 예술의 이해는 새로운 예술의 존재에 정당성을 부여하고, 그 필요성을 인식할 때 가능하다. 그러한 관점에서 본 연구에서 다룬 김구림의 작업들 역시 한국 미술사에서 실험미술의 시작에 위치한다는 점, 곧 시대가 요구한 예술의 내용과 형식의 변화를 감지하여 구현했다는 점에서 그 의미를 찾을 수 있다. This research aims to study the significance of Kulim Kim‘s avant-garde art, who made the early step to experimental art in Korea. The subject of the study is mail art, happenings, and the Fourth Group movement that he participated in from 1969 to 1970. < Relics of Mass Media >, < Condom & Carbamine >, and < The Happening on the Overpass > were the series of works that Kim and his fellow artists performed for the new form of art, avant-garde. < Relics of Mass Media > introduced and implemented letters as a new medium to Korean art. The recipients of the letter became creators of the art and the value. The work, < Condom & Carbamine >, tried to break the stereotypes of objects and perceptions that proposed a new way of art appreciation. At < The Happening on the Overpass >, more than a hundred balloons were hung on the overpass and allowed pedestrians to walk through, was also a new attempt that inevitably required the participation of people. The artist intended to break boundaries made between the artist and the audience in the production and reception of the art. Later, he went ahead to the culture-criticizing works by participating in the Fourth Group. While insisting on the liberation of human nature and criticizing the existing art and culture, the Fourth Group pursued conceptual art. Although Kim is regarded as an avant-grade artist, the question has remained unanswered as to what Kim's avant-garde is. This study will explore the answers in the artist's attempt that pursued a new art, and expand it through Renato Poggioli's avant-garde theory. As Poggioli has stated, the understanding of avant-garde art is possible when it gives legitimacy to the existence of new art itself and recognizes its necessity. From that point of view, Kim's works, dealt with in this study, have meanings that occupy the beginning period of the experimental art of Korea. His works sensed a demand given by the time he lived in; to change the content and form of art and actualize it in artistic forms.

<i>BRCA1/2</i> somatic mutation detection in formalin-fixed paraffin embedded tissue by next-generation sequencing in Korean ovarian cancer patients

Lee, Ahwon,Kang, Jun,Lee, Hyoungnam,Lee, Youn Soo,Choi, Youn Jin,Lee, Keun Ho,Nistala, Goutam J,Scafe, Charles R.,Choi, Jongpill,Yoo, Jaeeun,Han M.D, Eunhee,Kim, Yonggoo,Kim, Myungshin Elsevier 2019 Pathology, research and practice Vol.215 No.11

<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>The detection of <I>BRCA1/2</I> mutations is important because PARP1 inhibitors are approved for germline and/or somatic <I>BRCA</I>-mutated advanced ovarian cancer. Next-generation sequencing (NGS) is increasingly used in clinical practice for <I>BRCA1</I>/2 mutations. The purpose of this study was to consider several conditions of NGS <I>BRCA1/2</I> assay applicable to clinical laboratory tests, in particular for using formalin fixed paraffin embedded (FFPE) ovarian tissues.</P> <P><B>Materials and methods</B></P> <P>We selected 64 ovarian cancer patients and performed Oncomine™ BRCA assay using FFPE tissue. Effect of FFPE sample quality was analyzed by NGS quality parameters including deamination metric. Somatic variants were selected by removing germline variants of peripheral blood and interpreted as pathogenic, variants of unknown significance, and false positive.</P> <P><B>Results</B></P> <P>We found a positive relationship between the number of variants over the deamination metric and FFPE age (<I>P</I> < 0.001) with a cutoff values of approximately 0.7 and 60 months, respectively. When comparing NGS results with Sanger sequencing, NGS misreported 3 of 15 variants using default parameters which were corrected after changing parameters. We detected somatic variants in eight patients and classified them into pathogenic (n = 3), VUS (n = 3) and false positive (n = 2).</P> <P><B>Conclusions</B></P> <P>This study is important for improving <I>BRCA1/2</I> mutation detection capabilities of NGS analytical pipelines and strategy to overcome their limitations using FFPE tissue in ovarian cancer patients.</P>

Polymeric white organic light-emitting diodes with two emission layers.

Lee, Sungkoo,Im, Yirang,Lee, Kyeong K,Lim, Eunhee American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.4

<P>A white light-emitting diode was fabricated by preparing multilayer emitting films with an inserted buffer layer. The device structures are ITO/PEDOT:PSS/Emissive layer/LiF/Al. The emissive layer comprises a yellow-emitting layer of Poly[9,9-dioctylfluorenyl-2,7-diyl]-co-1,4-benzo-(2,1,3)-thiadiazole (F8BT), a blue-emitting layer of Poly[9,9-di-(2'-ethylhexyl)fluorenyl-2,7-diyl] (BEHF) and PEDOT:PSS as a buffer layer between the emission layers. The solution processed multi-layer polymer light-emitting diodes (PLED) were prepared by introduction of a water-soluble buffer layer between organic solvent soluble layers. We present white organic light-emitting diodes (WOLEDs) that has bilayer emission zones. This device exhibits a brightness of 280 cd/m2 and emission efficiency of 1.18 cd/A at 12.6 V. The device with a doped PEDOT:PSS layer and a thicker blue-emission layer exhibits CIE color coordinates of (0.30, 0.34), which is close to the white coordinates of (0.33, 0.33) used by the standard CIE color coordinates.</P>

NMR and Fluorescence Studies of DNA Binding Domain of INI1/hSNF5

Lee, Dongju,Moon, Sunjin,Yun, Jihye,Kim, Eunhee,Cheong, Chaejoon,Lee, Weontae Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.9

INtegrase Interactor 1 protein (INI1/hSNF5) or BRG1-associated factor 47 (BAF47) is a SWI/SNF-related matrix associated actin dependent regulator of chromatin subfamily B member. DNA binding domain of INI1/hSNF5 is cloned into E.coli expression vectors, pET32a and purified as a monomer using size exclusion chromatography. NMR data show that $INI1^{DBD}$ has folded state with high population of ${\alpha}$-helices. By fluorescence-quenching experiments, binding affinities between $INI1^{DBD}$ and two double stranded DNA fragments were determined as $29.9{\pm}2.6{\mu}M$ (GAL4_1) and $258.7{\pm}5.8$ (GAL4_2) ${\mu}M$, respectively. Our data revealed that DNA binding domain of INI1/hSNF5 binds to transcriptional DNA sequences, and it could play an important role as a transcriptional regulator.

Preliminary Methodology for Linking Data

Eunhee Ha,Jueun Lee,Byung-Hak Jeon,Myeongjee Lee 환경독성보건학회 2015 한국독성학회 심포지움 및 학술발표회 Vol.2015 No.10

Effective establishment of mouse model of premature ovarian failure considering treatment duration of anticancer drugs and natural recovery time

( Eunhee Lee ),( Kayeong Yun ),( Sieun Han ),( Bosun Joo ),( Kyusup Lee ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: The aim of this study was to suggest the most effective primary ovarian insufficiency(POI) model construction method by examining the effect of POI model on anticancer drugs. Methods: Female mice were treated with cyclophosphamide(Cy)+busulfan(Bu) mixture for 1 week to 4 weeks and Cisplatin alone for 3, 5, 10, and 14 days. The injection period to POI occurrence was observed and the period of normal recovery from POI was checked. Results: After two weeks of the Cy+Bu injection, the weight of ovary and uterus decreased sharply and the weight reductions also affect ovarian function. And ovarian function is not recovered for at least 2 weeks when POI is induced with Cy+BU for 2 weeks. After 10 days of Cisplatin injection, the weight of ovary and uterus decreased significantly and the weight reductions also affect ovarian function. After 10 to 2 weeks of treatment with cisplatin, the embryo development rate to blastocyst was 0%. Conclusion: As an ideal POI induction model, it is useful to treat Cy+Bu for 2 weeks or cisplatin for 10 days to 2 weeks.

Simple Bithiophene-Rhodanine‐Based Small Molecule Acceptor for Use in Additive‐Free Nonfullerene OPVs with Low Energy Loss of 0.51 eV

Lee, Taeho,Eom, Yoonho,Song, Chang Eun,Jung, In Hwan,Kim, Dongwook,Lee, Sang Kyu,Shin, Won Suk,Lim, Eunhee Wiley (John WileySons) 2019 Advanced energy materials Vol.9 No.16

Risk Factors of Depressive Symptoms among Community-Dwelling Elderly

Eunhee Lee 국제문화기술진흥원 2018 International Journal of Advanced Culture Technolo Vol.6 No.2

The purpose of this study was to assess risk indicators of depressive symptoms such as demographic, socio-economical domains (age, gender, marital status, education, child, religion, income, health, friendship) and personality domains (neurotic personality, self-esteem and life goal attitude) of community dwelling elderly persons. A total of 300 community-residing elderly participants aged 65+ in a metropolitan city in Korea, were recruited for this interview survey. The interview covered demographic and socio-economic characteristics, and administration of the 20-item Korean Version of CES-D, the 10-item Self-esteem, the 19-item Neuroticism and the 10-itm Goal Instability scale. The prevalence of significant depressive symptoms (CES-D scale >= 21) was 31%. Logistic regression analysis showed high risk for depression was associated with high neuroticism, less intimate friendship, high goa1 instability, and childlessness, respectively in the order of significance. Factors in the personality domains were more strongly associated with depressive symptoms than factors in the socio- economical domains. Both cultural and universal meaning of the findings was discussed with regard to intervention.

Risk Factors of Depressive Symptoms among Community-Dwelling Elderly

Lee, Eunhee The International Promotion Agency of Culture Tech 2018 International Journal of Advanced Culture Technolo Vol.6 No.2

The purpose of this study was to assess risk indicators of depressive symptoms such as demographic, socio-economical domains (age, gender, marital status, education, child, religion, income, health, friendship) and personality domains (neurotic personality, self-esteem and life goal attitude) of community dwelling elderly persons. A total of 300 community-residing elderly participants aged 65+ in a metropolitan city in Korea, were recruited for this interview survey. The interview covered demographic and socio-economic characteristics, and administration of the 20-item Korean Version of CES-D, the 10-item Self-esteem, the 19-item Neuroticism and the 10-itm Goal Instability scale. The prevalence of significant depressive symptoms (CES-D scale >= 21) was 31%. Logistic regression analysis showed high risk for depression was associated with high neuroticism, less intimate friendship, high goa1 instability, and childlessness, respectively in the order of significance. Factors in the personality domains were more strongly associated with depressive symptoms than factors in the socio- economical domains. Both cultural and universal meaning of the findings was discussed with regard to intervention.

Synthesis and characterization of regioregular alkyl-substituted poly(3,4-ethylenedioxythiophenes).

Lee, Sungkoo,Lee, Kyeong K,Lim, Eunhee,Son, Ha-Young American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.5

<P>In order to increase the solubility of PEDOT, we introduced an alkyl chain into polymer backbone. Depending on the position of the alkyl bond, the steric hindrance between the alkyl chains can also leads to regioregularity in the polymer. The regioregular polymers can easily occur self-assembly, both in solution and in the solid state, resulting in highly ordered two- and three-dimensional polymer architectures. A series of soluble regioregular alkyl-substituted PEDOTs were synthesized using the Grignard Metathesis (GRIM) for the purpose of study on regiorandom and regioregular PEDOT. The ethylene proton adjacent to the oxygen atom of regioregular methoxydodecyl-PEDOT appears at 3.51 ppm, whereas the corresponding peak of regiorandom methoxydodecyl-PEDOT appears at 3.42 ppm.</P>