A STUDY ON ASSIMILATION RULES OF TURKISH LEARNERS

M. Ertan GÖKMEN(M. Ertan GÖKMEN) 이중언어학회 1999 이중언어학 Vol.16 No.1

Procedural and Early Outcomes of Two Re-entry Devices for Subintimal Recanalization of Aortoiliac and Femoropopliteal Chronic Total Occlusions

Ertan Vuruskan,Erhan Saracoglu 대한심장학회 2017 Korean Circulation Journal Vol.47 No.1

Background and Objectives: Subintimal angioplasty is a common treatment choice for chronic total occlusions (CTO) in the iliac and femoropopliteal arteries. This article describes the technical aspects and early outcomes of two different re-entry devices and comparison with manual re-entry technique. Subjects and Methods: A retrospective review of 61 patients (re-entry group) treated with Outback or Pioneer Plus catheters was carried out. A matched cohort of patients (n=62) who underwent lower extremity interventions without the use of re-entry devices (manual reentry group) were also analyzed (overall 123 patients were analyzed). Procedural success, procedural durations, patency estimates, anklebrachial indices, and complications were analyzed. Results: Sixty-one patients underwent Outback or Pioneer Plus guided subintimal recanalization. After the procedure, ankle-brachial indices significantly increased in all patients during follow-up. Primary patency for the entire cohort was 83% in the first month. When the re-entry device group was compared with manual re-entry group, no difference was found with respect to success, complication, and patencies between the two groups during follow-up. However, procedure duration and the amount of contrast agent used was significantly decreased in re-entry groups (p<0.001). Also, re-entry time was significantly decreased in Pioneer plus group according to Outback group (p<0.001) Conclusion: Recanalization of CTO using re-entry devices for aortoiliac or femoropopliteal arteries is safe and effective. These devices shorten the procedure time, the re-entry time, reduce radiation risk, and reduce the amount of contrast agent employed.

Development and evaluation of a multiplex PCR assay for simultaneous detection of Flavobacterium psychrophilum, Yersinia ruckeri and Aeromonas salmonicida subsp. salmonicida in culture fisheries

Ertan Emek Onuk,Arzu Findik,Yuksel Durmaz,Alper Ciftci 대한수의학회 2010 Journal of Veterinary Science Vol.11 No.3

Bacterial cold water disease, enteric red mouth disease and frunculosis are the common bacterial diseases of fish worldwide. The etiologic agents of these diseases are Flavobacterium (F.) psychrophilum, Yersinia (Y.) ruckeri and Aeromonas (A.) salmonicida subsp. salmonicida, respectively. In this study, a multiplex polymerase chain reaction (m-PCR)method with YER8/10-Fer3/4-FP1/3 primer pairs which can identify these fish pathogens simultaneously was developed and optimized. In optimized conditions, neither false specific nor nonspecific amplification occurred. The detection limits of the m-PCR method using DNA extracts from dilutions of pure cultures of bacteria were 35 pg for Y. ruckeri and F. psychrophilum and 70 pg for A. salmonicida subsp. salmonicida. It was determined that 15 CFU Y. ruckeri and F. psychrophilum and 30 CFU A. salmonicida subsp. salmonicida could be detected by m-PCR developed using genomic DNA extracted from dilutions of the suspensions. The detection limits in the presence of tissue debris were 125 CFU for Y. ruckeri and F. psychrophilum and 250 CFU for A. salmonicida subsp. salmonicida. In conclusion, we submit that the m-PCR method developed and optimized in this study can be used for accurate and rapid identification of these bacteria.

The Korean Studies in Turkey

Mahmut Ertan GOKMEN 한국중동학회 2000 韓國 中東 學會 論叢 Vol.21 No.2

Cultural Aspect of Conflict Behaviour in Construction -A Case Study from Turkey

Babaoglu, F.Fusun Ertan,Giritli, Heyecan Korea Institute of Construction Engineering and Ma 2017 Journal of construction engineering and project ma Vol.7 No.2

Although much research has been conducted to identify the influence of culture on conflict management and resolution behaviours in organizational settings, no study has been done yet in the construction industry particularly in considering the influence of individual level individualistic and collectivistic values. Despite the key role of self-construal in explaining or predicting behaviour in interpersonal conflict, it has not received enough attention in construction management. Reflecting this necessity, the objective of this exploratory study was to establish, through the application of the Rahim Organizational Inventory (ROC II) instrument, how the cultural values of professionals of construction businesses relate to the application of different conflict-handling styles through self-construal. Data were collected using questionnaire surveys from construction professionals working in contracting firms. The findings illustrate the importance of self-construal type as an individual-level cultural variable in explaining the differences in the style of handling interpersonal conflict in the context of the construction industry.

Protective Role of Grape Seed Extract Against Doxorubicin-Induced Cardiotoxicity and Genotoxicity in Albino Mice

Emine Yalçin,Ertan Oruç,Kültiğin Çavuşoğlu,Kürşad Yapar 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.4

In this study, the protective role of grape seed extract (GSE) against doxorubicin (DOX)-induced cardiotoxicity and genotoxicity has been evaluated in male Mus musculus var. albino mice. The micronucleus (MN) test in erythrocytes and the chromosome aberration (CA) test in bone marrow cells were used. Also, levels of reduced glutathione (GSH) and lipid peroxidation as malondialdehyde (MDA) in heart homogenates were measured, and in addition the changes in heart histology were investigated. The mice were randomly divided into six groups. Group I (negative control) received intraperitoneal injections of isotonic saline (0.02mL/g) for 6 consecutive days, Group II received intraperitoneal injections of DOX (2.5mg/kg of body weight, six doses every other day; cumulative dosage, 15mg/kg of body weight) for 6 consecutive days, Group III received GSE (50mg/kg of body weight, 21 doses every other day; cumulative dosage, 1,050mg/kg of body weight) for 21 consecutive days, Group IV received GSE (150mg/kg of body weight, 21 doses every other day; cumulative dosage, 3,150mg/kg of body weight) for 21 consecutive days, Group V received GSE (50mg/kg of body weight, 28 doses every other day; cumulative dosage, 1,400mg/kg of body weight) for 28 consecutive days plus DOX (2.5mg/kg of body weight, six doses every other day; cumulative dosage, 15mg/kg of body weight) for 6 consecutive days, and Group VI received GSE (150mg/kg of body weight, 28 doses every other day; cumulative dosage, 4,200mg/kg of body weight) for 28 consecutive days plus DOX (2.5mg/kg of body weight, six doses every other day; cumulative dosage, 15mg/kg of body weight) for 6 consecutive days. DOX induced heart damage as indicated from a pronounced change in heart histology. In the DOX-treated group, there was a significant increase in MDA content in the heart homogenate, and the level of GSH was significantly decreased. DOX induced genotoxicity by increasing the number of aberrant metaphases (AMNs), MNs, and structural chromosomal aberrations (CAs) such as chromatid breaks, dicentrics, acentric fragments, and gaps and showed a detractive effect on the mitotic index (MI) of cells. Pretreatment with GSE before treatment with DOX significantly protected the heart tissue by ameliorating its antioxidant activity. In Groups V and VI, the MDA level of heart tissue was significantly decreased, and the GSH level was increased compared to the DOX-treated group. Moreover, GSE significantly protected bone marrow chromosomes from DOX-induced genotoxicity by reducing the total AMNs and the frequency of structural CAs. GSE treatment also decreased the frequency of MNs and increased the MI values. It could be concluded that GSE acts as a potent antioxidant to prevent heart damage and genotoxicity of bone marrow cells.

Exogenously Applied Glycine Betaine Regulates Some Chemical Characteristics and Antioxidative Defence Systems in Lettuce under Salt Stress

Mostafakamal Shams,Ertan Yildirim,Melek Ekinci,Metin Turan,Atilla Dursun,Fazilet Parlakova,Raziye Kul 한국원예학회 2016 Horticulture, Environment, and Biotechnology Vol.57 No.3

We investigated the effects of exogenous glycine betaine (GB) applications on antioxidant enzyme activity, dry matter, and the contents of organic acids, amino acids, total antioxidants, and total phenolics in lettuce, Lactuca sativa, under salt stress. The treatments included four concentrations of GB (0, 5, 10, and 25 mM) and two levels of salinity (0 and 100 mM of NaCl). The 25 mM GB treatment increased dry matter and the content of total phenolics in lettuce plants compared to the non-GB-treated plants under salt stress. Salinity (100 mM NaCl without GB) significantly reduced dry matter, total phenolic content, and total antioxidant content in the plants. However, the lettuce plants grown under salt stress generally had higher amino acid and organic acid contents than those grown under non-salinity conditions. GB treatments had different effect on amino acid and organic acid contents under salinity conditions. Superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and ascorbate peroxidase (APX) activities were elevated under the 100 mM NaCl and 0 mM GB treatments, whereas higher concentrations of GB decreased them under salt stress. The 25 mM GB treatment mitigated the negative effect of salt stress and increased the dry matter by 44% compared to the plants that were treated with 100 mM NaCl and 0 mM GB. The results suggested that exogenous GB treatments could ameliorate the tolerance of lettuce to salt stress by increasing the total antioxidants and total phenolics, and regulating antioxidant enzyme activity, and altering the contents of organic acids and amino acids.

Preparation and Characterization of Polyethylene Glycol Functional Hydroxyapatite/Polycaprolactone Electrospun Biomembranes for Bone Tissue Engineering Applications

Emre Yavuz,Ramazan Erdem,Ertan Küçüksayan,Esin Akarsu,Murat Akarsu 한국섬유공학회 2021 Fibers and polymers Vol.22 No.5

Surfaces of previously synthesized Hydroxyapatite particles (HAP) have been modified with polyethylene glycolfunctional silane (PEG-400Si). For the surface modification of HAP, firstly, synthesis of PEG-400Si was performed byurethane reaction of hydroxyl and isocyanate groups. Then, HAP was synthesized by sol-gel method. Afterwards, surfacemodification of HAP was realized with PEG-400Si. SEM, TEM, XRD and FTIR analyses were utilized to characterize themorphology and structural properties of the synthesized and modified particles. Results revealed that the surface of HAP wasmodified successfully and the crystal structure of HAP was not changed after modification. Electrospinning process wasconducted to obtain unmodified and modified HAP incorporated nanofibrous biomembranes and the characteristics andbiological performances of these membranes have been compared to each other. SEM analysis presented that defect-free andround shape nanofibers obtained and the fiber diameter ranged from 230±114 nm to 760±291 nm. In vitro biologicalevaluations revealed that all electrospun nanofibrous biomembranes were nontoxic and the one with PCL/PEG-400Si-HAPexhibited greatest cellular protein expression approximately 1.5 times higher than the PCL biomembrane for 24 h, 48 h and72 h.

Protective Effect of Ginkgo biloba L. Leaf Extract Against Glyphosate Toxicity in Swiss Albino Mice

Kültiğin Çavuşoğlu,Kürşad Yapar,Ertan Oruç,Emine Yalçın 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.10

The aim of the present study was to investigate the protective role of Ginkgo biloba L. leaf extract against the active agent of Roundup^ⓡ herbicide (Monsanto, Creve Coeur, MO, USA). The Swiss Albino mice were randomly divided into six groups, with each group consisting of six animals: Group I (control) received an intraperitoneal injection of dimethyl sulfoxide (0.2 mL, once only), Group II received glyphosate at a dose of 50 mg/kg of body weight, Group III received G. biloba at a dose of 50 mg/kg of body weight, Group IV received G. biloba at a dose of 150 mg/kg of body weight, Group V received G. biloba (50 mg/kg of body weight) and glyphosate (50 mg/kg of body weight), and Group VI received G. biloba (150 mg/kg of body weight) and glyphosate (50 mg/kg of body weight). The single dose of glyphosate was given intraperitoneally. Animals from all the groups were sacrificed at the end of 72 hours, and their blood, bone marrow, and liver and kidney tissues were analyzed for aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine, malondialdehyde (MDA), and glutathione (GSH) levels and the presence of micronucleus (MN), chromosomal aberrations (CAs), and pathological damages. The results indicated that serum AST, ALT, BUN, and creatinine levels significantly increased in mice treated with glyphosate alone compared with the other groups (P<.05). Besides, glyphosate-induced oxidative damage caused a significant decrease in GSH levels and a significant increase in MDA levels of the liver and kidney tissues. Moreover, glyphosate alone–treated mice presented higher frequencies of CAs, MNs, and abnormal metaphases compared with the controls (P<.05). These mice also displayed a lower mean mitotic index than the controls (P<.05). Treatment with G. biloba produced amelioration in indices of hepatotoxicity, nephrotoxicity, lipid peroxidation, and genotoxicity relative to Group II. Each dose of G. biloba provided significant protection against glyphosate-induced toxicity, and the strongest effect was observed at a dose of 150 mg/kg of body weight. Thus, in vivo results showed that G. biloba extract is a potent protector against glyphosate-induced toxicity, and its protective role is dose-dependent.

Protective Effect of Royal Jelly and Green Tea Extracts Effect Against Cisplatin-Induced Nephrotoxicity in Mice: A Comparative Study

Kürşad Yapar,Kültiğin Çavuşoğlu,Ertan Oruç,Emine Yalçin 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.5

The aim of the present study was to investigate the protective role of royal jelly (RJ) and green tea (GT) extracts on cisplatin (cDDP)-induced nephrotoxicity in adult albino mice. Albino mice were randomly divided into six groups: Group I (control) received a single intraperitoneal injection of isotonic saline (0.02mL/g), Group II received a single intraperitoneal injection of cDDP (7mg/kg of body weight), Group III received RJ (100mg/kg of body weight), Group IV received GT (100mg/kg of body weight), Group V received RJ (100mg/kg of body weight)+cDDP (7mg/kg of body weight), and Group VI received GT (100mg/kg of body weight)+cDDP (7mg/kg of body weight). The concentrations of blood urea nitrogen (BUN) and creatinine were evaluated. In addition, kidney samples were taken for determination of tissue malondialdehyde (MDA) and reduced glutathione (GSH) levels. In addition, histopathological changes in kidneys were investigated. The results indicated that no significant differences in MDA, GSH, BUN, and creatinine levels were observed among the control group and groups treated with RJ alone and GT alone (P>.05). However, there was a significant increase in BUN and creatinine parameters after cDDP application in Groups II, V, and VI. The mice treated with only cDDP exhibited an increase in serum BUN and creatinine levels when compared to Groups V and VI (P<.05). Moreover, cDDP-induced oxidative damage caused a significant decrease in GSH levels and a significant increase in MDA levels in kidneys (P<.05). RJ and GT supplementation attenuated cDDP-induced nephrotoxicity, which was manifested by stopping the elevation in serum creatinine and BUN levels. Moreover, RJ and GT supplementation restored GSH content and MDA production levels in the kidney tissue following cDDP treatment (P<.05). These products were also effective in protecting against cDDP-induced tissue damage in mouse kidneys. In conclusion, 100mg/kg of body weight doses of RJ and GT provided protection against cDDP-induced nephrotoxicity, and both products can act as protector agents against cDDP-induced kidney damages.