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      • KCI등재

        Expression analyses of soybean genes encoding methionine-Rsulfoxide reductase under various conditions suggest a possible role in the adaptation to stress

        Ha Duc Chu,Kim-Lien Nguyen,Yasuko Watanabe,Dung Tien Le,Lam-Son Phan Tran 한국응용생명화학회 2016 Applied Biological Chemistry (Appl Biol Chem) Vol.59 No.5

        Under stress, plant cellular proteins can be oxidized at multiple amino acid residues causing protein dysfunction that may lead to reduced viability of plants. One of the oxidized amino acids, methionine sulfoxide (MetO), was frequently found in stressed plants. In soybeans, there are five methionine-R-sulfoxide reductases (GmMSRBs) responsible for the reduction of Met-R-O, one of the two MetO isomers. To identify GmMSRBs that may be involved in repairing Met-R-O under different stress conditions, we determined transcript levels of GmMSRBs in various tissues subjected to dehydration/drought, high salinity, and abscisic acid (ABA) during different developmental stages. Under normal conditions, expression levels were the highest in leaves, followed by roots, and lowest in seeds and seed pods. Among the GmMSRBs, transcripts of GmMSRB1 in the leaves were the highest; at the same time, GmMSRB5 was shown to be expressed at the lowest levels. Expression of GmMSRBs were then determined under stress-inducing conditions. In seedling shoots, GmMSRB2 and GmMSRB5 were expressed in response to drought conditions. In vegetative V6 trifolia, only GmMSRB3 was induced under drought. In reproductive R2 trifolia, the expression of GmMSRB2 and GmMSRB5 were induced by drought. However, expressions of all five GmMSRBs in the roots were not affected by the any stressinducing conditions. Under salt stress, GmMSRB1 was downregulated in seedling shoots and GmMSRB5 was up-regulated in seedling roots. Treatment with ABA did not affect the transcript levels of any GmMSRBs in seedling shoots. However, this treatment up-regulatesGmMSRB2 in seedling roots. Our data suggested that with the exception of GmMSRB4, all the remaining four GmMSRBs play a role in soybean responses to multiple environmental stresses and that genes encoding cytosolic and plastidic GmMSRBs respond differently under stress.

      • KCI등재

        Understanding the COVID-19 Infodemic: Analyzing User-Generated Online Information During a COVID-19 Outbreak in Vietnam

        Ha-Linh Quach,Thai Quang Pham,Ngoc-Anh Hoang,Dinh Cong Phung,Viet-Cuong Nguyen,Son Hong Le,Thanh Cong Le,Dang Hai Le,Anh Duc Dang,Duong Nhu Tran,Nghia Duy Ngu,Florian Vogt,Cong-Khanh Nguyen 대한의료정보학회 2022 Healthcare Informatics Research Vol.28 No.4

        Objectives: Online misinformation has reached unprecedented levels during the coronavirus disease 2019 (COVID-19) pandemic. This study analyzed the magnitude and sentiment dynamics of misinformation and unverified information about public health interventions during a COVID-19 outbreak in Da Nang, Vietnam, between July and September 2020. Methods: We analyzed user-generated online information about five public health interventions during the Da Nang outbreak. We compared the volume, source, sentiment polarity, and engagements of online posts before, during, and after the outbreak using negative binomial and logistic regression, and assessed the content validity of the 500 most influential posts. Results: Most of the 54,528 online posts included were generated during the outbreak (n = 46,035; 84.42%) and by online newspapers (n = 32,034; 58.75%). Among the 500 most influential posts, 316 (63.20%) contained genuine information, 10 (2.00%) contained misinformation, 152 (30.40%) were non-factual opinions, and 22 (4.40%) contained unverifiable information. All misinformation posts were made during the outbreak, mostly on social media, and were predominantly negative. Higher levels of engagement were observed for information that was unverifiable (incidence relative risk [IRR] = 2.83; 95% confidence interval [CI], 1.33–0.62), posted during the outbreak (before: IRR = 0.15; 95% CI, 0.07–0.35; after: IRR = 0.46; 95% CI, 0.34-0.63), and with negative sentiment (IRR = 1.84; 95% CI, 1.23–2.75). Negatively toned posts were more likely to be misinformation (odds ratio [OR] = 9.59; 95% CI, 1.20–76.70) or unverified (OR = 5.03; 95% CI, 1.66–15.24). Conclusions: Misinformation and unverified information during the outbreak showed clustering, with social media being particularly affected. This indepth assessment demonstrates the value of analyzing online “infodemics” to inform public health responses.

      • SCIEKCI등재

        Expression analyses of soybean genes encoding methionine-R-sulfoxide reductase under various conditions suggest a possible role in the adaptation to stress

        Chu, Ha Duc,Nguyen, Kim-Lien,Watanabe, Yasuko,Le, Dung Tien,Tran, Lam-Son Phan The Korean Society for Applied Biological Chemistr 2016 Applied Biological Chemistry (Appl Biol Chem) Vol.59 No.5

        Under stress, plant cellular proteins can be oxidized at multiple amino acid residues causing protein dysfunction that may lead to reduced viability of plants. One of the oxidized amino acids, methionine sulfoxide (MetO), was frequently found in stressed plants. In soybeans, there are five methionine-R-sulfoxide reductases (GmMSRBs) responsible for the reduction of Met-R-O, one of the two MetO isomers. To identify GmMSRBs that may be involved in repairing Met-R-O under different stress conditions, we determined transcript levels of GmMSRBs in various tissues subjected to dehydration/drought, high salinity, and abscisic acid (ABA) during different developmental stages. Under normal conditions, expression levels were the highest in leaves, followed by roots, and lowest in seeds and seed pods. Among the GmMSRBs, transcripts of GmMSRB1 in the leaves were the highest; at the same time, GmMSRB5 was shown to be expressed at the lowest levels. Expression of GmMSRBs were then determined under stress-inducing conditions. In seedling shoots, GmMSRB2 and GmMSRB5 were expressed in response to drought conditions. In vegetative V6 trifolia, only GmMSRB3 was induced under drought. In reproductive R2 trifolia, the expression of GmMSRB2 and GmMSRB5 were induced by drought. However, expressions of all five GmMSRBs in the roots were not affected by the any stressinducing conditions. Under salt stress, GmMSRB1 was down-regulated in seedling shoots and GmMSRB5 was up-regulated in seedling roots. Treatment with ABA did not affect the transcript levels of any GmMSRBs in seedling shoots. However, this treatment up-regulates GmMSRB2 in seedling roots. Our data suggested that with the exception of GmMSRB4, all the remaining four GmMSRBs play a role in soybean responses to multiple environmental stresses and that genes encoding cytosolic and plastidic GmMSRBs respond differently under stress.

      • KCI등재

        Hybrid Optimization for Distribution Channel Management: A Case of Retail Location Selection

        Nhu-Mai Thi NONG,Duc-Son HA 한국유통과학회 2021 유통과학연구 Vol.19 No.12

        Purpose: This study aims to introduce a hybrid MCDM model to support the selection of retail store location. Research design, data, and methodology: The hybrid approach of ANP and TOPSIS was used to address the location selection problem. The ANP technique was employed to compute the weights of the selection criteria, whilst the TOPSIS was used to rank alternatives. The proposed approach was then applied into a fashion company in Vietnam to select the best alternatives to be the retail store. Results: The results showed that Candidate 1 – Hai Ba Trung street is the most appropriate selection for locating retail stores. Conclusions: The proposed approach provides the decision makers with more useful methods than traditional ones. Therefore, the model can be applied to the location selection in all industries. In terms of academic contribution, the selection criteria proposed in the research can devote to the literature in the selection of location along with the concept of distribution channels. Additionally, the research also provides insight and guidelines for firms in making decision on retail store location based on limited resources to avoid the waste of funds. However, the results only answer to the context of Vietnam - a developing country. Thus, future research may be extended to developed countries where have better conditions.

      • SCIESCOPUS

        Alkylphloroglucinol derivatives and triterpenoids with soluble epoxide hydrolase inhibitory activity from Callistemon citrinus

        Khanh, P.N.,Duc, H.V.,Huong, T.T.,Son, N.T.,Ha, V.T.,Van, D.T.,Tai, B.H.,Kim, J.E.,Jo, A.R.,Kim, Y.H.,Cuong, N.M. Elsevier 2016 Fitoterapia Vol.109 No.-

        <P>Phytochemical analysis of the leaves and stems of Callistemon citrinus (Curtis) Skeels led to the isolation of two new alkylphloroglucinols, gallomyrtucommulone E and F (1 and 2), along with four other known alkylphloroglucinol derivatives, gallomyrtucommulone A (3), endoperoxide G3 (4), myrtucommulone B (5), callistenone B (6) and five known triterpenoids, induding betulinic acid (7), 3 beta-acetylmorolic acid (8), 3 beta-hydroxy-urs-11-en-13(28)olide (9), diospyrolide (10) and ursolic acid (11). The structures of the natural compounds were determined from the spectroscopic evidences including 1D-/2D-NMR and HR-MS spectrometry. All the isolated compounds were assessed for the effects on the sEH inhibitory activity. The acylphloroglucinols myrtucommulone B (5)/callistenone B (6) (in mixture), and two triterpenoids, ursolic acid (11) and 3 beta-hydroxy-urs-11-en-13(28)-olide (9) displayed strong inhibition of sEH activity, with IC50 values of 0.7, 112 and 24.8 mu M, respectively. (C) 2015 Elsevier B.V. All rights reserved.</P>

      • SCOPUSKCI등재
      • SCOPUS

        Determinants of Accountants' Loyalty Underlying Investment Management: Evidence from FDI Firms in Thanglong Industrial Park

        NGUYEN, Dang Huy,HA, Son Tung,TRAN, Manh Linh,NGUYEN, Duc Thang,NGUYEN, Thi Xuan Hong,NGUYEN, Dieu Linh,DO, Duc Tai Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.4

        The research aims to investigate the impact levels of determinants on the loyalty of accountants to FDI firms underlying investment management in Thanglong Industrial Park in Hanoi, Vietnam. We conducted a questionnaire consisting of 31 observation variables with a 5-point Likert scale. Independent variables were measured from 1 "without effect" to 5 "strongly". The method of data collection was done through the survey and subjects are accountants in FDI firms doing business in Thanglong Industrial Park in Hanoi. After checking the information on the votes, there are 120 questionnaires with full information for data entry and analysis, This study employs Cronbach's Alpha test, and regression model. The results show that seven determinants including Working environment, The characteristics of working; Training, promotion prospects and development; Income, Personal characteristic, Collective work together and The method of leading had positive relationships with the loyalty of accountants. Based on the findings, some recommendations are given related to such determinants to improve the loyalty of accountants of FDI firms in general and FDI firms in Thanglong Industrial Park in Hanoi in particular. With which, those firms can enhance performance, reduce financial strain, saving on investment in the recruiting process of new staff, increase profitability to ensure investment management.

      • SCOPUSKCI등재

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