급성 림프구성 백혈병 환자에서 아스페르길루스 감염을 동반한 호중구감소성 소장결장염에 의한 작은창자 천공

강동백,임태수,박원철,윤기중,이정균 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

저자들은 급성 림프구성 백혈병 치료 도중 아스페르길루스 감염을 동반한 호중구감소성 소장결장염에 의한 작은창자 천공을 경험하였다. 급성 림프구성 백혈병의 항암화학치료 중 발생 할 수 있는 호중구감소성 소장결장염은 다양한 위장관 증상을 보일 수 있으며, 이에 대한 발생 가능성을 고려하여 적극적인 조 기진단과 이에 대한 적극적 치료가 필요하며, 면역기능의 저하로 아스페르길루스 등의 진균 감염이 발생할 수 있으므로 호중구감소성 소장결장염의 치료에 증상의 호전이 없을 때 항진균제를 포함한 광범위한 치료가 고려되어야 한다. Though advancesin imumosuppressive therapy or chemotherapy which have lead to increased survival of leukemia and transplant patient, but the risk of infectious complication has been increasing. Neutropenic enterocolitis is a life threatening complication of chemotherapy for malignancies such as leukemia or lymphoma. Symptoms of neutropenic enterocolitis are nonspecific and it may rapidly lead to intestinal peforation. Aspergilus infection could involve the gastrointestinal tract as a result of neutropenia and mucosal injury after imumosuppressive therapy, chemoetherapy, or antibiotics use, but rarely reported a small bowel perforation combined aspergillus and neutropenic enterocolitis. We present a rare case of ileal perforation caused by neutropenic enterocolitis combined with aspergillus infection during chemotherapy for acute lymphocytic leukemia with a review of the literature.

흰쥐 Nucleus Raphe Magnus에 투여한 Morphine이 척수 Serotonin 유리에 미치는 영향에 관한 연구

이신재,임요한,최영님,김형룡,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.1

It is known that the interaction between opioid neuron and serotonergic neuron in bulbospinal pathway has an important role on pain control. This experiment was perfomed to directly measure the release of serotonin into spinal cord superfusates before and after the microinjection of morphine and its antagonist, naloxone into the NRM of rats. High performance liquid chromatography with electrochemical detection was used to quantitate the amine. The injection of morphine into the NRM induced a significant increase in the amount of serotonin released in the spinal cord, which was reversed after the intraperitioneal injection of naloxone. These results support the proposal that : the analgesia produced by morphine microinjected into the NRM is mediated by the activation of spinally projecting serotonergic neuron.

체외충격파 쇄석술 시행 후 5년 뒤 발생한 요관 협착 및 농신장 1예

이현승,권균홍,조용건,김봉진,임창섭,김자영,허동,임학 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

A 40-years-old woman was admitted to this hospital with flank pain and high grade fever for 2 weeks. As a matter of her past history, extracorporeal shock wave lithotripsy (ESWL) was performed for treatment of renal stones 5 years ago. Her abdominal CT findings were hydronephrosis with pyonephrosis and renal stones. Antibiotics administered for 5 days had no effects on her symptom improvement. A right ureteral stricture was noticed by ultrasonography follow up. We inserted double J stent and continued antibiotics therapy for 10 days, and then her fever was disappeared and flank pain was improved. ESWL is one of the most important treatment of renal and ureteral stone. However, its complications should not be negligible including bleeding, pain, ureteral obstruction, infection and so on. Complications of ESWL can be divided into acute and chronic courses. When we treat pyelonephritis patient with past history of ESWL, possibility of ureteral stricture must also be considered. In this study we report a case of pyelonephritis caused by ureteral stricture, possibly as a chronic complication of ESWL performed 5 years earlier

A Study on the Experiential Response of Short-Form Video Users

Lim, Dong Kyun The Institute of Internet 2021 International journal of advanced smart convergenc Vol.10 No.4

As society gradually enters a virtual, non-face-to-face society, the use of online content is increasing as well. In particular, as smartphones are thoroughly established in our daily life, the platforms of webtoons, mobile broadcasting, and education are shifting from personal computers to smartphones. Recently, the development of the Over-The-Top media service (OTT service) enabled streaming services of various media contents through the internet and activation of IPTV. Therefore, the rapid increase of popularity of short-form content is a natural phenomenon with smartphone platforms with fast, improvised, and endless communication. Lately, TikTok became the favored platform with prosumers, defined as people who are both producers and consumers. In this study, I studied the experiential response of YouTube and TikTok users as representative examples of a short-form content platform developed after the 2000s, the flourishing years of digital content with a length of 30 seconds.

A Novel Surrogate-Assisted Multi-Objective Optimization Algorithm for an Electromagnetic Machine Design

Dong-Kuk Lim,Dong-Kyun Woo,Han-Kyeol Yeo,Sang-Yong Jung,Jong-Suk Ro,Hyun-Kyo Jung IEEE 2015 IEEE transactions on magnetics Vol.51 No.3

<P>To design electric machines, the motor performance, cost, and manufacturing have to be considered. Hence, researchers have called this the multi-objective optimization (MOO) problem in which the goal is to minimize or maximize several objective functions at the same time. In order to solve the MOO problem, various algorithms, such as nondominated sorting genetic algorithm II and multi-objective particle swarm optimization, have been widely used. When these algorithms are applied to the electric machine design, much time consumption is inevitable due to many times of function evaluations using a finite-element method. To solve this problem, a novel surrogate-assisted MOO algorithm is proposed. Its validity is confirmed by comparing the optimization results of test functions with conventional optimization methods. To verify the feasibility of its application to a practical electric machine, an interior permanent magnet synchronous motor is designed.</P>

Factors Related to Sleep Disorders among Male Firefighters

Dong-Kyun Lim,Ki-Ook Baek,In-Sung Chung,Mi-Young Lee 대한직업환경의학회 2014 대한직업환경의학회지 Vol.26 No.-

Objectives: The aim of this study was to investigate factors associated with sleep disorders in male firefighters working in a metropolitan city in South Korea. Methods: Self-administered questionnaires including the Nordic Musculoskeletal Questionnaire, Korean Occupational Stress Scale-Short Form, Psychosocial Well-Being Index-Short Form, Pittsburg Sleep Quality Index, and Beck-Depression Inventory-2 as well as surveys collecting socio-demographic characteristics and work-related factors were given to 730 male firefighters. After exclusion for missing data, 657 male firefighters were included, and logistic regression analysis adjusted for the work-related factors, psychosocial factors, and general risk factors were used to assess the relationship between sleep disorders and associated factors. Results: The prevalence of sleep disorders was 48.7%. Shift work (adjusted OR 1.58, 95% CI = 1.02-2.45), musculoskeletal symptoms (adjusted OR 2.89, 95% CI = 2.02-4.14), and depression (adjusted OR 7.04 95% CI = 4.03-12.30) were associated with sleep disorders. Conclusions: Musculoskeletal symptoms, shift work, and depression are associated with sleep disorders. Integrated health management is needed to promote good sleep quality among firefighters.

Effect of Manufacturing Method and Acidifier on the Dissolution Rate of Carvedilol from Solid Dispersion Formulations

Lim, Dong-Kyun,Bae, Jeong-Woo,Song, Byung-Joo,Jo, Han-Su,Kim, Hyoung-Eun,Lee, Dong-Won,Khang, Gil-Son The Korean Society of Pharmaceutical Sciences and 2011 Journal of Pharmaceutical Investigation Vol.41 No.6

In this study, we demonstrated the release behavior of carvedilol with the content of polyvinylpyrrolidone K-30 (PVP K-30) and the effect of citric acid and fumaric acid as acidifiers on the release behavior of drug. In addition, it tries to inquire into the release behavior difference of the carvedilol according to the manufacturing method. The release behavior of the tablets was compared with Dilatrand$^{(R)}$ in the simulated gastric fluid (pH1.2). Differential scanning calorimeter (DSC), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) were characterized for the physicochemical properties of the tablets. In case of mixing the carvedilol and PVP K-30, in case the ratio of the carvedilol and PVP K-30 was 1:5, the release behavior was the highest among. As well as the dissolution rate of tablets manufactured by lyophilization and rotary evaporator was higher than physical mixture. The dissolution rate of containing acidifiers was more improved. But, rather the excessive amount of the acidifier addition reduced the dissolution rate.

A Study on the Experiential Response of Short-Form Video Users

Dong Kyun Lim 한국인터넷방송통신학회 2021 Journal of Advanced Smart Convergence Vol.10 No.4

As society gradually enters a virtual, non-face-to-face society, the use of online content is increasing as well. In particular, as smartphones are thoroughly established in our daily life, the platforms of webtoons, mobile broadcasting, and education are shifting from personal computers to smartphones. Recently, the development of the Over-The-Top media service (OTT service) enabled streaming services of various media contents through the internet and activation of IPTV. Therefore, the rapid increase of popularity of short-form content is a natural phenomenon with smartphone platforms with fast, improvised, and endless communication. Lately, TikTok became the favored platform with prosumers, defined as people who are both producers and consumers. In this study, I studied the experiential response of YouTube and TikTok users as representative examples of a short-form content platform developed after the 2000s, the flourishing years of digital content with a length of 30 seconds.

Microprocessor On-line Contents using Simulator

Dong Kyun Lim,Won Geun Oh 국제문화기술진흥원 2020 International Journal of Advanced Culture Technolo Vol.8 No.4

With the advancement of the 4th Industrial Revolution(4IR), microprocessor education is on the rise due to the explosive demand for IoT (Internet of Things) and M2M devices. However, it is difficult due to many constraints to efficiently transfer training on hardware assembly and implementation through online training. Thus, we developed a cost-effective online content based on Arduino simulations, Atmel Studio 7, and WinAvr simulator that are required for the utilization of AVR 128. These Camtasia videos overcame the limitation of theory focused on-line education by visually introducing the practical utilization of an actual AVR 128. In this paper, the proposed educational content was provided to university students, and the results of student feedback show that it has a strong effect.

자기등가회로를 이용한 매입형 영구자석 전동기의 공극 자속 밀도 계산

임동국(Dong-Kuk Lim),우동균(Dong-Kyun Woo),여한결(Han-Kyeol Yeo),노종석(Jong-Suk Ro),정현교(Hyun-Kyo Jung) 대한전기학회 2013 대한전기학회 학술대회 논문집 Vol.2013 No.4