Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

이차원 보증정책의 비용분석 모형

김제승,이영규 尙志大學校 生産技術硏究所 1999 生産技術論叢 Vol.7 No.-

A two-dimensional warranty policy is characterized by a region in a two-dimensional plane with one axis representing time or age and the other representing item usage, such as the age and mileage of an automobile. This paper proposes a new two-attributes warranty policy that the failed product is free-replaced by producer in the replacement and minimally free-repaired by producer in the repair regions. We obtain expressions for the expected warranty costs under some assumptions about usage and failure and illustrate through numerical examples.

스쿠버 활동시 감압증 이론과 관련한 제요인의 원인과 예방법에 관한 고찰

류재청 濟州大學敎 體育科學硏究所 1997 체육과학연구 Vol.3 No.-

This review was undertaken to search the way for safe diving concerned with decompression sickness and types. Nitrogen saturation diving. Recompression equipments and theories of decompresiion sickness 1. The orgin og decompression theory Recent all theories of decompression sickness was originated from 「Caisson or Bends」 mean and based on Haldene thoery(1908). Theory shifted rom Haldene theory after that were theory of saturation diving. Haldane-Royal Navy table. U.S. Navy Diving Table(1965). Royal Navy Theory. Swiss theory, Canada theory, Dive Science and Technology Corporation(DSAT. 1987) 2. Women and decompression Woman were more suspectible to deccompression sickness than men because of first. having more body fat tissue. second more supectible decompression due to stream of body fluid during mensturation. third unbalanced circulation due to birth control pill. The symptoms generating in diving of pregnanent women consist of squeeze, air embolism. Decompression sickness but these did not any problem on fetus. 3. Equipments for prevention of decompression sickness 1) Dive tables Many decompression tables developed on the basis of on U.S. Navy Diving Table used Haldene theory were NAUI. PEDI. BASAC etc. and the content composed in common was to avoid decompression sicness in safety stop(3min stop at 15 feet). The skill to be practice on dive tables conist of resign of repetitive diving letter. Adjusted Maximum Dive Time(AMDT). min. surface interval time). Allowable max. depth in repetitive diving. RNT. SIT etc. 2) Gagues The most popular gauage using to avoid decompression sickness were capillary type depth gauge. diaphragm type depth gauge, oil-filled type depth gauge, analog digital type, analog digital submersible type. dive computer. Particularly It is recommanded to use dive computer display accurate absorption of Nitrogen, depth to avoid penalty of 「maximum-time at maximum-depth」 in multi-level diving. 3) Decompression prevention It is said to redecompression to treat serious symptom of decompression & air embolism. operated in recompression chambers. If you omitted safety stop. It is necessory to position of shock prevention, must be rest providing with pure 100% oxygen certifing symptom of decompression sickness, and be carried to hyperbaric facility. The height of flying after dive must not be superceded 8000 feet, at least before 24 hours. It is desirable to dive shorter and deeper than shallower and longer diving when scheduled of flight.

Heinrich Heine 詩論 : 特히 "Neue Gedichte"를 中心으로

轉在弘 釜山大學校 師範大學 1978 교사교육연구 Vol.5 No.1

Welch ein Lied! "Eine gewaltige Lust ergreift mich! Wa˝hrend ich sitze, und schreibe, erklingt Musik unter meinem Fenster, und an dem elegischen Grimm der lang-gezogenen Melodie, erkenne ich jene Marseiller Hymne, womit der scho˝ne Barbaroux und seine Gefa˝hrten die. Stadt Paris begru˝Bten, jener Kuhreigen der Freiheit, bei dessen To˝nen die Schweizer in den Tuilerien das Heimweh bekamen, jener triumphierende Todesgesang der Gironde, das alte su˝Be Wiegenlied-Es durehschauert mich mit Feuer und Freude, und entzU˝ndet in mir die glU˝henden Sterne der Begeisterung und die Raketen des Spottes. Ja, diese sollen nicht fehlen, bei dem groBen Feuerwerk der Zeit. Klingende Frammenstro˝me des Gesanges sollen sich ergieBen von der Ho˝he der Freiheitslust, in ku˝hnen Kaskaden, wie sich der Ganges herabstU˝rzt vom Himalaya! Und du, holde Satyra, Tochter der gerechten Themis und des bocksfu˝Bigen Pan, leih mir deine Hu˝lfe, Du bist ja mu˝tterlicher Seite dem Titanengeschlechte entsprossen, und hassest gleich mir die Feinde deiner Sippschaft, die schwa˝chlichen Usurpatoren des Olymps. Leih mir das Schwert deiner Mutter. damit ich sie richte, die verhaBte Brut, und gib mir die Picke-lflo˝te deines Vaters, damit ich sie zu Tode pfeife-">>schrieb Heinrich Heine die Spa˝tere Nachschrift der'〉Reisebilder'<<schon im November 1830. Nachdem Heine den Reisestoff auf die beschriebene Weise aufgearbeitet hatte, war er in politischer Hinsicht fu˝r ihn abgeschlossen. Heines Bedu˝rfnis nach Variation lieB eine einfache Wiederholung nicht zu. So arbeitete er mit neuem Stil das>'Neuer Fru˝hling'<1828/31von der Neuen Gedichte in Hamburg auf. Die Chance fu˝r eine. Realisierung ist hier gro˝Ber. In dieser Phase ist ihm die politisch-gesellschaftliche Aufgabe wichtiger als die dichterische. Denn Heine mo˝chte als politischer Befreier in die Geschichte eingehen. Auch an seinen Werk Neuer Fru˝hling<' wendet sich das Technische von Metrik, Sprache und Form.

建築의 立面表現과 記號論 : 주택의 입면경관표현에 관한 기호론적 분석

林采震 홍익대학교환경개발연구원 1994 환경개발연구논문집 Vol.1 No.-

The purpose of this study is to find out whether there is a sign system in suburban housing elevation. The form of Housing functions not only for use but also for sign which has effect on [mentality of human life]. However, in a recently according as the variety of construction become divergent the type of housing stops to be vigible and disorder among the visual elevations disturbs the goal of elevational view of housing planning because planning is generally consisting in a conventional code which provides a proper signification for a type. Therefore, this study tries to make up a code through analyzing the correlations among visual aspects or collected from 20 individual houses. As a result of quantifying analysis based on matrix of two characteristic, the author concludes that several types are visible on two significant units, i.e. [site plan] and [Facade].

지속적인 음악 줄넘기 운동이 초등학생의 기초체력 및 흥미도에 미치는 영향

문채련 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

The study was performed to make a comparison and to analyse the effect on basic physical strength and interesting degree of primary school students by continuous "skipping rope to music". The test was done in a way that the experimental group of 119 persons and the comparative studying group of 113 persons were tested and analyzed about "physical elasticity, agility, balancing power, sustaining power of heart and lungs, pliability, and interesting degree" before and after skipping rope to music. It was resulted that in the first, continuous skipping rope to music makes considerable effects to improve physical adjusting abilities (physical elasticity, balancing power, agility) and especially, showed the considerable change on statistical data of physical elasticity. In the second, continuous skipping rope to music made significant effects to advance sustaining power of heart and lungs, which may lead to increase of sustaining power of heart and lungs and to improvement of physical circulation system. In the third, muscular strength whs considerably increased by the continuous skipping rope to music, In the fourth the continuous "skipping rope to music" made student think about skipping rope in a good way and it was found that students were more interested in skipping rope together with others than in doing that alone. In line with the above facts, 36 weeks of skipping rope to music resulted in improvement and advancement of basic physical power of primary school students, and it played an important role to make students get interested in doing that, and furthermore, the continuous development of physical training program is expected in the future for a large number of primary school students through readjusting training times and level of "skipping rope to music".