Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

두 가지 고장 형태를 가진 제품의 비용모형

김제숭 尙志大學校 生産技術硏究所 2000 生産技術論叢 Vol.8 No.-

This paper is concerned with warranty cost models for a product with two types of failure: type1 failures corrected by minimal repair and type2 failures removed only by replacement. Two warranty policies involving an initial free service period followed by a pro-rata period are considered; the difference is whether the warranty is renewed or not when type2 failure occurs during its free service period. Expected warranty costs under the two policies are obtained, and their behaviors are examined for the case where type 1 and 2 failure distributions are Weibull and exponential, respectively.

建築의 立面表現과 記號論 : 주택의 입면경관표현에 관한 기호론적 분석

林采震 홍익대학교환경개발연구원 1994 환경개발연구논문집 Vol.1 No.-

The purpose of this study is to find out whether there is a sign system in suburban housing elevation. The form of Housing functions not only for use but also for sign which has effect on [mentality of human life]. However, in a recently according as the variety of construction become divergent the type of housing stops to be vigible and disorder among the visual elevations disturbs the goal of elevational view of housing planning because planning is generally consisting in a conventional code which provides a proper signification for a type. Therefore, this study tries to make up a code through analyzing the correlations among visual aspects or collected from 20 individual houses. As a result of quantifying analysis based on matrix of two characteristic, the author concludes that several types are visible on two significant units, i.e. [site plan] and [Facade].

부하수준에 따른 보행양상과 일치도에 관한 연구

류재청,김철원 제주대학교 1994 논문집 Vol.39 No.-

동작의 일치하는 정도를 분석하기 위해 적용된 동작은 정상보행동작이었고, 이 때 부하는 체중에 대해 0%BW, 20%BW, 40%BW의 부하를 달리하여 정상보행의 양상과 운동학적 변인간의 인지계수(Recoginition coefficient; Mallwain J.S. 등, 1985)를 구하기 위해 실험 및 분석한 결과 다음과 같은 결론을 얻었다. 부하의 종류가 0%BW, 20%BW일 때 정상보행동안 다른 운동학적 변인간의 인지능력에는 큰 차이를 보이지 않지만 부하가 40%BW이상 및 특수상황과 과부하 보행시에는 인지능력이 감소하여 일치도가 떨어졌다. 동일한 운동학적 변인에서 부하를 달리했을 때 히프각과 무릎각은 부하조건에 상관없이 높은 부하일수록 높은 인지능력을 보였고, 동작의 일치도가 높았다. 히프각속도와 무릎각속도는 부하를 하였을 때 일치감소하였고, 부하조건 간에는 일치도가 매우 높고, 인지능력은 증가했다. 신체중심변위의 경우 부하 및 무부하간의 일치하는 정도는 다소 높은 것으로 나타났고, 부하의 종류에 따라 큰 영향을 받지 않았지만, 신체중심속도는 부하의 종류에 따라 일치도는 감소하여 동작의 인지능력은 적었다. The study was undertaken to investigate congruity of kinematic variables on a kind of load level(%BW) during normal gait with packback system, and the congruity degree was represented with recognition coefficient. The difference of recognition ability between 0%BW and 20%BW was little, but was not in 40%BW, over load situation and grately dropped congruity among other kinematic during variable normal gait. The congruity of hip & knee angle was shown high regardless of loaded conditions in the same kinematic variables, was reduced in hip & knee angular velocity loaded and was shown high between loaded conditions, recognition ability was increased. The congruity degree of COG displacement was rather high in all load level, and was not influenced by load levels, but was decresed according to load levels in COG velocity.

DCT 기반 영상압축에서 각 블록의 구성요소 선택 기준

조제황 東新大學校 1997 論文集 Vol.9 No.-

The DCT is applied to a 8×8 block and the low frequency coefficients are selected to compress. Because RMSE and the standard deviation for unselected coefficients versus each block present similar distribution, the standard deviation can be utilized to decrease the complexity and bit rate of a compression system. In 3 to 5 standard deviation, the proposed method has around 2dB lower PSNR than only b selection, but has the number of coefficients around four times as small as only b selection.

숙련자와 미숙련자의 배드민턴 스매시 동작의 운동학적 비교 분석

류재청,김익상 한국운동역학회 2003 한국운동역학회지 Vol.13 No.2

Ryew, C-C and Kim, I-S. Kinematic Analysis of Badminton Smashing Between the Skilled and the Unskilled. Korean Journal of Sport Biomechanics, Vol. 13, No. 2, pp. 139-160. The purpose of this study was to suggest the guideline for scientific and quantitative skill acquisition methods of badminton smashing so that the novice could learn the motions of badminton smashing efficiently. The subject participated consisted of total 6 middle school students of the skilled(3) and the unskilled(3). The cinematographical experimental & Analysis equipments used in the study were composed of two Model D-5100 Video Cameras, a control point, a synchronization timer and Kwon3d motion analysis system. The conclusions obtained were as follows; 1. It was necessary for the unskilled to learn the smashing impact phase in situation of max. Velocity of COG in order to minimize the timing loss phase. 2. Particularly, The power from segments of Power Zone must participate in utilization in sequence of order of trunk-upper arm-forearm-hand-racket segment in both the skilled and the unskilled. 3. Therefore It was necessary for the unskilled to do smashing practice for cumulated sum of absolute & relative velocity transfer into shuttle cock after adjusting anterior-posterior tilting angle and max timing, in sequence of segment recruited.