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      • PVD 방법에 의한 TiN barrier metal 형성과 공정개발

        염병렬,박형호,최치규,이종덕,김건호,이정용,서경수,강민성 濟州大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.10 No.2

        Ar과 N₂?가스가 혼합된 분위기에서 반응성 스퍼터링 방법에 의하여 TiN 박막을 증착하였다. N₂ 가스의 농도는 화학양론적으로 TiN이 형성되는 조건에 맞도록 조절하였으며, 기판의 온도는 실온에서 부터 700℃의 범위내로 유지하였다. (111) texture 구조를 가지면서 화학양론적으로 Ti??N??인 박막은 기판의 온도가 600℃ 이상에서 형성되었고, 기판의 온도가 600℃ 이하에서는 형성된 박막은 N-과다형이었다. XRD, XPS 및 RBS 분석 결과 TiN 박막의 조성비는 기판의 온도에서 다소 의존하였으나 약 5% 이내에 불과하였다. TiN 박막의 면저항은 기판온도의 증가에 따라 감소하였고, 기판온도가 600℃에서 증착된 TiN 박막의 면저항능 14.5Ω/□ 였고, Ar―가스 분위기에서 700℃로 30초간 열처리한 후는 8.9Ω/□ 이었다. 따라서 반응성 스퍼터링방법에 의하여 형성되는 양질의 TiN 박막은 기판온도가 600℃이상이 최적조건임을 알았다. Titanium nitride (TiN) films were prepared by reactive sputter deposition in mixed gas of Ar+N₂?. The volume percentage of N₂ in the working gas was chosen so as to grow stoichiometric TiN films and the substrate temperature during film growth was set from room temperature to 700℃. stoichiometric Ti??N?? films with (111) texture were grown at temperatures over 600℃, while films prepared at temperatures below 600℃ showed N-rich TiN. The composition x and y in the Ti??N?? films determined by XPS and RBS varied within 5% with the substrate temperature. The sheet resisstance of the TiN films decreases as the substrate temperature increased. TiN film prepared at 600℃ showed 14.5Ω/□, and it decreased to 8.9Ω/□ after the sample was annealed at 700℃, 30 sec in Ar-gas ambient by RTA. By far, high quality stoichiometric TiN films by reactive sputtering in the mixed gas ambient could be prepared at substrate temperature over 600℃.

      • 상처치유시 Antisense TGF-β1 Oligodeoxynucleotides가 Inducible Nitric Oxide Synthase발현 조절에 미치는 영향

        최병민,곽현정,전창덕,임정식,박석돈,정헌택 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.4

        Wound healing in the skin may be complicated by both microbial invasion and inflammation. Following injury, platelet degranulation releases a number of chemotactic factors including transforming growth factor (TGF-fl) and platelet derived growth factor (PDGF). TGF-19 is a cytokines that modulates many cellular function and gene expression. However, it is not known whether TGF-P could regulate inducible nitric oxide synthase (iNOS) gene expression during wound healing. Here we report that down regulation of TGF-Q gene expression by antisense oligodeoxynucleotides increase iNOS during wound healing. Our reverse transcription- polymerase chain reaction (RT-PCR) result has shown that antisense TGF-fil oligodeoxynucleotides (ODN) targeting the TGF-J11 translation initiation region markedly reduced TGF-(il mRNA levels in wounded skin. Also, marked reduction in TGF-fl1 mRNA after antisense treatment invited that the increment of iNOS mRNA in wounded skin. Therefore, our irnmunohistochemical studies revealed a "pattern of iNOS product in wounded skin treated antisense TGF-fl1 ODN that was similar to the pattern of RNA synthesis detected by RT-PCR. In conclusion, our results indicated that the regulatory actions of TGF fl1 on iNOS. might be involved in the initiation and faciliates the resolution of inflammation following wounding.

      • KCI등재

        남자 알코올 의존 환자의 기질적 특성에 관한 연구

        김성곤,민영기,이덕기,김미영,송영상,권도훈,고영훈,박제민,정병선 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.1

        목 적: 본 연구의 목적은 한국인 남자 알코올 의존 환자의 기질적 특성을 Temperament and Character Inventory(TCI)를 이용하여 조사하는 것이다. 방 법: DSM-Ⅳ 진단 기준에 맞는 알코올 의존 환자 30명과 정상인 36명을 대상으로 연구학적 특성을 조사하고, 기질적 특성을 한글판 TCI를 이용하여 조사하였다. 모든 대상자의 나이는 30~60세였다. 결 과: 1) 두 군간 평균 나이는 유의한 차이가 없었으나, 교육 정도와 결혼을 유지하고 있는 비율 및 취업률은 알코올 의존군이 정상 대조군에 비해 유의하게 낮았다. 2) 알코올 의존군에서는 정상 대조군에 비해 Harm Avoidance(HA) 점수와 Self-transcendence(ST)점수는 유의하게 높았으며, Self-directiveness(SD)점수는 유의하게 낮았다. 3) 알코올 의존군 내에서의 각 척도들 간의 상관관계는, HA와 SD 점수, HA와 Persistence(PE) 점수, ST와 SD 점수는 각각 유의한 음의 상관관계, ST와 PE 점수, SD 점수와 Cooperativeness(CO) 점수, Reward Dependence(RD)와 CO 점수는 양의 상관관계를 보였다. 결 론: 이러한 본 연구의 결과는 한국인 남성에서 수줍음을 잘 타며, 걱정도 많고, 염세적이고 쉽게 피로해지는 기질적 특성이 알코올 의존과 연관성이 있음을 의미한다. Objectives : The purpose of this study was to assess the temperament of male parients with alcohol dependence. Methods : The subjects were 30 patients who met DSM-Ⅳ criteria for alcohol dependence and 36 normal controls. All subjects completed Temperament and Character Inventory(TCI) which was developed by Cloninger. Results : 1) The educational level, marital status, and occupation in alcohol dependence group were significantly lower than those of normal control group, but there was no difference in the age between two groups. 2) Among the scores of TCI, the score of harm avoidance(HA) and self-transcendence(ST) were significantly higher in the alcohol dependence group than in the normal control group. 3) In the alcohol dependence group, a significant negative correlation among the scores of TCI was between HA and SD, HA and Persistence(PE), ST and SD, and positive correlation between ST and PE, SD and Cooperativeness(CO), Reward Dependence(RD) and CO. Conclusion : These results suggest that shy, fearful, pessimistic and fatigable temperament are related to developing alcohol dependence in Korean males.

      • 자발성 뇌교출혈 환자의 예후에 관한 임상 분석

        조재영,석종식,민병국,권정택,최덕영,황성남,김영백,박승원 중앙대학교 의과대학 의과학연구소 2002 中央醫大誌 Vol.27 No.1

        Patients with spontaneous pontine hemorrhage very often develop setvere disturbances of consciousness,pupilary abnormalities, respiratory and motor. They have high mortality rate. Therefore, I analyzed the correlation between the Glasgow outcome scale(GOS)and clincial manifestations or computed tomographic(CT)findings in 48 patients with spontaneous pontine hemorrhage to clarify factors predicting the prognosis. I examined 48 Patients with spontaneous pontine hemorrhage; 33 males and 15 females, age 54.6±8.99(mean±S.D.;range 39 to 68)brought to our hospital between January 1995 and December 1999, retrospectively. Correlations between the clinical manifestations, CT findings and the GOS was assessed with multivariate regression analysis. The results were as follow: 1) Patients with the pontine hemorrhage were of 8.8% in those with intracerebral hemorrhage. The ratio of male and female was 33 to 15. The incidence of age is eqial to 40,50 and 60. Total mortality was 41.6%. 2) The poor prognostic factor were that; Glasgow coma scale(GCS)3∼8, irregular respiration. pupilary abnormality, quadriplegia, Brain CT typeⅠ(massive), hydrocephalus, extrapontine extension, Intraventricular hemorrhage(IVH). These clinical analysis should be useful in determining the level of care and future resuscitative efforts.

      • KCI등재

        Poroid hidradenoma of the scalp

        Min, Byung Duk,Lee, Chong Kun,Chung, Chang Eun,Kim, Dong Chul,Paik, So Ya Korean Cleft Palate-Craniofacial Association 2021 Archives of Craniofacial Surgery Vol.22 No.3

        Poroid hidradenoma has both features of hidradenoma and poroma. The histological hidradenoma framework consisting of solid and cystic components, and the presence of poroid and cuticular cells resembling a poroid neoplasm. Despite transforming into malignant neoplasm only in < 1% of cases, its histological characteristics may resemble those of malignant neoplasms. Although the risk of malignant transformation is very low, surgical excision is recommended to prevent growth and/or recurrence. To date, very few cases of poroid hidradenoma have been reported in the literature. Herein, we present a case of poroid hidradenoma on the scalp of a 74-year-old woman.

      • SCIESCOPUSKCI등재

        A Novel Grid-Connected PV PCS with New High Efficiency Converter

        Min, Byung-Duk,Lee, Jong-Pil,Kim, Jong-Hyun,Kim, Tae-Jin,Yoo, Dong-Wook,Ryu, Kang-Ryoul,Kim, Jeong-Joong,Song, Eui-Ho The Korean Institute of Power Electronics 2008 JOURNAL OF POWER ELECTRONICS Vol.8 No.4

        In this paper, new topology is proposed that can dramatically reduce the converter power rating and increase the efficiency of total PV system. Since the output voltage of PV module has very wide voltage range, in general, the DC/DC converter is used to get constant high DC voltage. According to analysis of PV characteristics, in proposed topology, only 20% power of total PV system power is needed for DC/DC converter. DC/DC converter used in proposed topology has flat efficiency curve at all load range and very high efficiency characteristics. The total system efficiency is the product of that of converter and that of inverter. In proposed topology, because the converter efficiency curve is flat all load range, the total system efficiency at the low power range is dramatically improved. The proposed topology is implemented for 200kW PCS system. This system has only three DC/DC converters with 20kW power rating each other. It is only one-third of total system power. The experiment results show that the proposed topology has good performance.

      • A Novel Grid-Connected PV PCS with New High Efficiency Converter

        Byung Duk Min,JongPil. Lee,Jong-Hyun Kim,Tae-Jin Kim,Dong-Wook Yoo,Kang Ryoul Ryu,Jung Joong Kim,Eui-Ho Song 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-

        In this paper, new topology is proposed that can dramatically reduce the converter power rating and increase the efficiency of total PV system. Since the output voltage of PV module has very wide voltage range, in general, the DC/DC converter is used to get constant high DC voltage. According to analysis of PV characteristics, in proposed topology, only 20% power of total PV system power is needed for DC/DC converter. DC/DC converter used in proposed topology has flat efficiency curve at all load range and very high efficiency characteristics. The total system efficiency is the product of that of converter and that of inverter. In proposed topology, because the converter efficiency curve is flat all load range, the total system efficiency at the low power range is dramatically improved. The proposed topology is implemented for 200㎾ PCS system. This system has only three DC/DC converters with 20㎾ power rating each other. It is only one-third of total system power. The experiment results show that the proposed topology has good performance.

      • KCI등재

        A Novel Grid-Connected PV PCS with New High Efficiency Converter

        Byung-Duk Min,Jong-Pil Lee,Jong-Hyun Kim,Tae-Jin Kim,Dong-Wook Yoo,Kang-Ryoul Ryu,Jeong-Joong Kim,Eui-Ho Song 전력전자학회 2008 JOURNAL OF POWER ELECTRONICS Vol.8 No.4

        In this paper, new topology is proposed that can dramatically reduce the converter power rating and increase the efficiency of total PV system. Since the output voltage of PV module has very wide voltage range, in general, the DC/DC converter is used to get constant high DC voltage. According to analysis of PV characteristics, in proposed topology, only 20% power of total PV system power is needed for DC/DC converter. DC/DC converter used in proposed topology has flat efficiency curve at all load range and very high efficiency characteristics. The total system efficiency is the product of that of converter and that of inverter. In proposed topology, because the converter efficiency curve is flat all load range, the total system efficiency at the low power range is dramatically improved. The proposed topology is implemented for 200㎾ PCS system. This system has only three DC/DC converters with 20㎾ power rating each other. It is only one-third of total system power. The experiment results show that the proposed topology has good performance.

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