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Bok Hee Kim,Mi Rae Jo,Dae Won Kim,Ki Un Kang,Su Gwan Kim,Jae Sung Kim,Sook Young Lee 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.10
Background : Bitter gourd (Momordica charantia) is a vegetable with pantropical distribution and contains the active ingredient, such as momordicine and charantin. Moreover, bitter gourd has been reported to exhibit antidiabetic, anticancer, cardiovascular-protective and antioxidant effects. But, the distinctive bitter taste of bitter gourd was not suitable for food preference. This study was conducted to evaluate the improvement effects of bitter taste of bitter gourd with natural fermentation and roasting process. Methods and Results : Bitter gourd fruits were obtained from Headeulnyeokae Co., Ltd.(Gang-Jin 59253, Repubilc Korea). Fruits of bitter gourd were prepared by natural fermentation process for 4h at 25℃. After natural fermentation, the fruits were dried in hot-air dryer for 15h at 49-55℃. The dried fruits were roasted in 500 g batches at 120℃ for 10 min in the electric rotisserie oven. After roasting, fruit pieces were extracted with hot water and cold water. One of them was cool-type, and the other was hot-type bitter gourd tea. In the sensory evaluation, hot tea and cold tea showed the high scores on color, flavor and overall acceptability. Conclusion : These mean that roasted bitter gourd had less bitter, and it could be utilized widely as drink and food material.
Bok, Won-Mi,Kim, Seo-Young,Lee, Sook-Jeong,Shin, Gwi-Su,Park, Ju-Mi,Lee, Min-Ho Korean Society for Precision Engineering 2015 International Journal of Precision Engineering and Vol.16 No.10
Titanium and titanium alloys are amenable to processing as dental implant materials because of their low density, good mechanical properties, better biocompatibility, and excellent corrosion resistance. However, titanium-based implants cannot bond directly to bone. To induce osseointegration, numerous surface-treatment techniques have been investigated over the years to improve implant performance. In this study, we examine sandblasting and acid etching (SLA) methods to determine the various properties of SLA-treated Ti-10Nb-10Ta alloy. The SLA treatment included two steps: first, mechanically polished Ti-10Nb-10Ta alloy was subjected to grit blasting using <TEX>$110-{\mu}m$</TEX> alumina particles, and second, the blasted alloy underwent acid etching for 9 minutes with a mixture of <TEX>$H_2SO_4$</TEX> and HCl at <TEX>$100^{\circ}C$</TEX>. After etching with Keller's etchant, the Ti-10Nb-10Ta alloy showed a lamellar structure on optical microscopy, and surface roughness was increased after SLA treatment (p<0.05). The apatite layer that formed on the SLA-treated Ti-10Nb-10Ta alloy after immersion in simulated body fluid was approximately <TEX>$2{\mu}m$</TEX> thick, thus improving adhesion to bone. Wettability of the SLA-treated Ti-10Nb-10Ta alloy was better than that of the non-treated one. In vitro studies showed no cytotoxicity from either the untreated or the SLA-treated Ti-10Nb-10Ta alloys.
Won-Suk Choi,Dae-Bok Kim,Young-Kyu Hong,Soon-Oh Kim,Sang-Woo Lee,Byung-Tae Lee,Sang-Hwan Lee,Mi-Jung Park,Sung-Chul Kim 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.1
This study was conducted to evaluate effect of chemical amendments on reducing bioavailable fraction of heavy metals in soil along with ecotoxicological effect on earthworms, Eisenia fetida. Three different chemical amendments, lime (L), steel slag (SS), and acid mine drainage sludge (AMDS), were applied with varied application ratio (1, 3, 5%). Heavy metal contaminated soil was mixed with chemical amedments and earthworms, Eisenia fetida, were cultivated for 28 days. Bioavailable fraction of heavy metals (Cd, Cu, Pb, and Zn) extracted with 0.1N HCl was monitored and also, mortality, growth, and metal concentration in earthworm were assessed. Result showed that all three amendments had high efficiency to reduce bioavailable fraction of heavy metals in soil. In particular, lime showed the highest reduction rate of Cu (63.9-87.7%), Pb (7.90-24.65%), and Zn (40.83-77.60%) among three amendments. No mortality of earthworm was observed during experimental period except 3% and 5% AMDS treatment indicating that application of chemical amendments is safe in terms of ecotoxicological aspect. However, no positive correlation was observed between reduction of bioavaialble fraction of heavy metals in soil and earthworms. Overall, application of chemical amendments in agricultural field can be adapted for reducing bioavailable fraction of heavy metals and detoxification in soil.
Bok-Nam Seo,박지은,Young-Eun Kim,Kyung-Won Kang,In-Chan Seol,Sun-Mi Choi 한국한의학연구원 2018 Integrative Medicine Research Vol.7 No.1
Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold–heat pattern. Methods: This study is designed as an intervention cohort study. Two hundred postmenopausal women aged <65 years with prehypertension or stage 1 hypertension living in Daejeon city in Korea will be recruited, and randomly assigned to either an acupuncture or no-treatment control group. The intervention will consist of four sessions; one session will include acupuncture performed 10 times for 4 weeks. There will be a 20-week observation period after each session, and the total study duration will be 96 weeks. Acupuncture will be applied at the bilateral Fengchi (GB20), Quchi (LI11), Zusanli (ST36), and Sameumgyo (SP6) acupoints. The effect of acupuncture will be evaluated by comparing the change in systolic and diastolic blood pressure between the acupuncture and control groups every 4 weeks until the end of the study. Discussion: To evaluate the success of blood pressure management, long-term observation is required, but no long-term studies have been conducted to evaluate the effect of acupuncture on blood pressure in postmenopausal women. To our knowledge, this study will be the first long-term study to investigate this issue for more than 6–8 weeks.