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      • KCI등재

        Power Sharing and Cost Optimization of Hybrid Renewable Energy System for Academic Research Building

        Anand Singh,Prashant Baredar 대한전기학회 2017 Journal of Electrical Engineering & Technology Vol.12 No.4

        Renewable energy hybrid systems look into the process of choosing the finest arrangement of components and their sizing with suitable operation approach to deliver effective, consistent and cost effective energy source. This paper presents hybrid renewable energy system (HRES) solar photovoltaic, downdraft biomass gasifier, and fuel cell based generation system. HRES electrical power to supply the electrical load demand of academic research building sited in 23° 12’ N latitude and 77°24’E longitude, India. Fuzzy logic programming discover the most effective capital and replacement value on components of HRES. The cause regarding fuzzy logic rule usage on HOMER pro (Hybrid optimization model for multiple energy resources) software program finds the optimum performance of HRES. HRES is designed as well as simulated to average energy demand 56.52 ㎾h/day with a peak energy demand 4.4 ㎾. The results shows the fuel cell and battery bank are the most significant modules of the HRES to meet load demand at late night and early morning hours. The total power generation of HRES is 23,794 ㎾h/year to the supply of the load demand is 20,631 ㎾h/year with 0% capacity shortage.

      • SCIESCOPUSKCI등재

        Power Sharing and Cost Optimization of Hybrid Renewable Energy System for Academic Research Building

        Singh, Anand,Baredar, Prashant The Korean Institute of Electrical Engineers 2017 Journal of Electrical Engineering & Technology Vol.8 No.1

        Renewable energy hybrid systems look into the process of choosing the finest arrangement of components and their sizing with suitable operation approach to deliver effective, consistent and cost effective energy source. This paper presents hybrid renewable energy system (HRES) solar photovoltaic, downdraft biomass gasifier, and fuel cell based generation system. HRES electrical power to supply the electrical load demand of academic research building sited in $23^{\circ}12^{\prime}N$ latitude and $77^{\circ}24^{\prime}E$ longitude, India. Fuzzy logic programming discover the most effective capital and replacement value on components of HRES. The cause regarding fuzzy logic rule usage on HOMER pro (Hybrid optimization model for multiple energy resources) software program finds the optimum performance of HRES. HRES is designed as well as simulated to average energy demand 56.52 kWh/day with a peak energy demand 4.4 kW. The results shows the fuel cell and battery bank are the most significant modules of the HRES to meet load demand at late night and early morning hours. The total power generation of HRES is 23,794 kWh/year to the supply of the load demand is 20,631 kWh/year with 0% capacity shortage.

      • KCI등재

        A Critical Aspect of Bioreactor Designing and Its Application for the Generation of Tissue Engineered Construct: Emphasis on Clinical Translation of Bioreactor

        Aditya Anand,Sarada Prasanna Mallick,Bhisham Narayan Singh,Shikha Kumari,Dheerendra Kumar Suman,Satyavrat Tripathi,Divakar Singh,Pradeep Srivastava 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.4

        Usage of bioreactors in the field of tissue engineering has played a significant role in enabling a controlled and reproducible change in the formation of damaged tissue on being provided with specific factors. Owing to the scarcity seen in providing sufficient donor organs for transplantation there is a huge requirement for large-scale production of artificial organs. This cannot be achieved by static culturing since it does not provide an invivo three-dimensional (3D) microenvironment therefore tissue engineering plays a vital role in the development of artificial tissues and organs as per the clinical demands whereas bioreactors have served a major role in providing the artificial microenvironment required by the cells to grow further into a tissue and then into an organ. By providing the specific biochemical cues and mechanoresponsive stimuli the bioreactors turn to be very effective in generating transplantable organs. Apart from performing studies in a controlled manner aimed at understanding biological and physicochemical effects, bioreactors also ensure the safe and reproducible production of tissueengineered constructs to achieve cost-effective large-scale production. The design criteria for bioreactors to be used in tissue engineering include optimal aspect ratio, proper aeration for the cells to proliferate, and agitation with reduced shear stress. The current review summarizes important aspects like Height/Diameter ratio or aspect ratio, shear stress, mechanical stress, aeration, agitation, oxygenation, etc. related to the design of tissue bioreactors, different types of bioreactors that are in use to date, and the reported pieces of literature to yield an overview on the existing concepts. It mainly focuses on the generation of 3D tissue constructs in various reactor systems specially designed for their culture and development along with their applications.

      • KCI등재후보

        Management of residual gall bladder

        Ashish Singh,Abhimanyu Kapoor,Rajneesh Kumar Singh,Anand Prakash,Anu Behari,Ashok Kumar,Vinay Kumar Kapoor,Rajan Saxena 한국간담췌외과학회 2018 Annals of hepato-biliary-pancreatic surgery Vol.22 No.1

        Backgrounds/Aims: A residual gallbladder (RGB) following a partial/subtotal cholecystectomy may cause symptoms that require its removal. We present our large study regarding the problem of a RGB over a 15 year period. Methods: This study involved a retrospective analysis of patients managed for symptomatic RGB from January 2000 to December 2015. Results: A RGB was observed in 93 patients, who had a median age of 45 (25-70) years, and were comprised of 69 (74.2%) females. The most common presentation was recurrence pain (n=64, 68.8%). Associated choledocholithiasis was present in 23 patients (24.7%). An ultrasonography (USG) failed to diagnose RGB calculi in 10 (11%) patients; whereas, magnetic resonance cholangio-pancreatography (MRCP) accurately diagnosed RGB calculi in all the cases except for 2 (4%) and, additionally, detected common bile duct (CBD) stones in 12 patients. Completion cholecystectomy was performed in all patients (open 45 [48.4%]; laparoscopic 48 [51.6%] and 19 [20.4%] patients required a conversion to open). The RGB pathology included stones in 90 (96.8%), Mirizzi’s syndrome in 10 (10.8%) and an internal fistula in 9 (9.7%) patients. Additional procedures included CBD exploration (n=6); Choledocho-duodenostomy (n=4) and Roux-en-Y hepatico-jejunostomy (n=3). The mortality and morbidity were nil and 11% (all wound infection), respectively. Two patients developed incisional hernia during follow up. The mean follow up duration was 23.1 months (3-108) in 65 patients and the outcome was excellent and good in 97% of the patients. Conclusions: Post-cholecystectomy recurrent biliary colic should raise suspicion of RGB. MRCP is a useful investigation for the diagnosis and assessment of any associated problems and provides a roadmap for surgery. Laparoscopic completion cholecystectomy is feasible, but is technically difficult and has a high conversion rate.

      • KCI등재

        Exploration of Appropriate Tool Material and Lubricant for Elevated Temperature Incremental Forming of Aluminium Alloy

        Swarit Anand Singh,Satwik Priyadarshi,Puneet Tandon 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.22 No.2

        In metal forming processes, the material of forming tools and lubricants play a very important role. It not only influences the forming process but also affects the surface finish of the produced product. Moreover, the product cost is directly associated with the cost of tools and lubricants. The present research explores appropriate tool materials and suitable lubricants to be used in Elevated Temperature Incremental Forming (ET-IF) of Aluminium alloy for efficient results. For the purpose, tool materials and lubricants used in Incremental Forming processes at higher temperatures were identified from the literature. The physical and chemical properties of the reported tool materials and lubricants, along with the established applications, were studied. Besides, the availability and cost of the lubricants, as well as machinability of the tool materials, were also considered to identify a set of feasible tool materials and lubricants for possible ET-IF applications. Subsequently, experiments were carried out with the identified set of tool materials and lubricants. Based on the observations made and the experimental results, different tool materials and lubricants were evaluated. The work recommends Tool steel (EN-31) and Molybdenum disulfide mixture as the most appropriate tool material and lubricant, respectively.

      • Progress in hybrid greenhouse solar dryer (HGSD): A review

        Singh, Pushpendra,Gaur, Manoj K.,Kushwah, Anand,Tiwari, G.N. Techno-Press 2019 Advances in energy research Vol.6 No.2

        The world population reaches to about 7.7 billion in 2018 from 6.2 billion in 2000. This much growth in population results in increased energy demand and increased food supply. As the conventional energy sources are limited. These may deplete soon if consumed at this rate. So, the world is switching towards the utilization of non-conventional sources of energy. Energy from sun is the best method as it can not only solve the energy issue but also helps in meeting food demand by conserving it. Greenhouses are made for the purpose of food conservation. Various types of solar dryers are developed by researchers till now and still the effort is being putted to make them more efficient. Hybrid greenhouse is also effort toward utilization of solar energy in more efficient way. The paper presents the heat and mass transfer analysis of hybrid greenhouse solar dryer developed by different researchers till now. The review helps the researcher in understanding the heat and mass transfer taking place inside the hybrid greenhouse and how it can be further improved.

      • SCOPUSKCI등재

        Use of thiopurines in inflammatory bowel disease: an update

        ( Arshdeep Singh ),( Ramit Mahajan ),( Saurabh Kedia ),( Amit Kumar Dutta ),( Abhinav Anand ),( Charles N. Bernstein ),( Devendra Desai ),( C. Ganesh Pai ),( Govind Makharia ),( Harsh Vardhan Tevethia 대한장연구학회 2022 Intestinal Research Vol.20 No.1

        Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight. 5-Aminosalicylates, corticosteroids, immunosuppressive agents and biologics are the backbone of treatment of IBD. With the advent of biologics and small molecules, the need for surgery and hospitalization has decreased. However, economic viability and acceptability is an important determinant of local prescription patterns. Nearly one-third of the patients in West receive biologics as the first/initial therapy. The scenario is different in developing countries where biologics are used only in a small proportion of patients with IBD. Increased risk of reactivation of tuberculosis and high cost of the therapy are limitations to their use. Thiopurines hence become critical for optimal management of patients with IBD in these regions. However, approximately one-third of patients are intolerant or develop adverse effects with their use. This has led to suboptimal use of thiopurines in clinical practice. This review article discusses the clinical aspects of thiopurine use in patients with IBD with the aim of optimizing their use to full therapeutic potential. (Intest Res 2022;20:11-30)

      • KCI등재

        A review on cholinesterase inhibitors for Alzheimer’s disease

        Preet Anand,Baldev Singh 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.4

        Alzheimer’s disease (AD), a progressiveneurodegenerative disorder, is characterized by the deficitsin the cholinergic system and deposition of beta amyloid(Ab) in the form of neurofibrillary tangles and amyloidplaques. Since the cholinergic system plays an importantrole in the regulation of learning and memory processes, ithas been targetted for the design of anti-Alzheimer’s drugs. Cholinesterase inhibitors enhance cholinergic transmissiondirectly by inhibiting the enzyme acetylcholinesterase(AChE) which hydrolyses acetylcholine. Furthermore, ithas been also demonstrated that both acetylcholinesteraseand butrylcholinesterase (BuChE) play an important role inAb-aggregation during the early stages of senile plaqueformation. Therefore, AChE and BuChE inhibition havebeen documented as critical targets for the effectivemanagement of AD by an increase in the availability ofacetylcholine in the brain regions and decrease in the Abdeposition. This review discusses the different classes ofcholinesterase inhibitors including tacrine, donepezil,rivastigmine, galantamine, xanthostigmine, para-aminobenzoicacid, coumarin, flavonoid, and pyrrolo-isoxazoleanalogues developed for the treatment of AD.

      • KCI등재

        Comparison of short-term outcomes of open and laparoscopic assisted pancreaticoduodenectomy for periampullary carcinoma: A propensity score-matched analysis

        Utpal Anand,Rohith Kodali,Kunal Parasar,Basant Narayan Singh,Kislay Kant,Sitaram Yadav,Saad Anwar,Abhishek Arora 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.2

        Backgrounds/Aims: Postoperative pancreatic fistula is the key worry in the ongoing debate about the safety and effectiveness of total laparoscopic pancreaticoduodenectomy (TLPD). Laparoscopic-assisted pancreaticoduodenectomy (LAPD), a hybrid approach combining laparoscopic resection and anastomosis with a small incision, is an alternative to TLPD. This study compares the short-term outcomes and oncological efficacy of LAPD vs. open pancreaticoduodenectomy (OPD). Methods: A retrospective analysis of data of all patients who underwent LAPD or OPD for periampullary carcinoma at a tertiary care center in Northeast India from July 2019 to August 2023 was done. A total of 30 LAPDs and 30 OPDs were compared after 1:1 propensity score matching. Demographic data, intraoperative and postoperative data (30 days), and pathological data were compared. Results: The study included a total of 93 patients, 30 underwent LAPD and 62 underwent OPD. After propensity score matching, the matched cohort included 30 patients in both groups. The LAPD presented several advantages over the OPD group, including a shorter incision length, reduced postoperative pain, earlier initiation of oral feeding, and shorter hospital stays. LAPD was not found to be inferior to OPD in terms of pancreatic fistula incidence (Grade B, 30.0% vs. 33.3%), achieving R0 resection (100% vs. 93.3%), and the number of lymph nodes harvested (12 vs. 14, p = 0.620). No significant differences in blood loss, short-term complications, pathological outcomes, readmissions, and early (30-day) mortality were observed between the two groups. Conclusions: LAPD has comparable safety, technical feasibility, and short-term oncological efficacy.

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