Four new species from the Agrilus wittemani species-group (Coleoptera: Buprestidae: Agrilini) from Silent Valley National Park, Southern Western Ghats, Kerala, India

Seena S.,Anand P.P.,Shibu Vardhanan Y. 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.2

The Agrilus wittemani species-group comprising six species from South and Southeast Asia; two of these are endemic to south India. Four new species of A. wittemani species-group Jendek & Nakládal, 2017 are described in this paper: Agrilus keralensis Seena, Anand and Shibu-Vardhanan sp. nov.; A. palakkadensis Seena, Anand and Shibu-Vardhanan sp. nov.; Agrilus sahyadriensis Seena, Anand and Shibu-Vardhanan sp. nov.; A. silentvalleyensis Seena, Anand and Shibu-Vardhanan sp. nov. A key to all species is provided and complemented with illustra tions of habitus and genitalia.

Programming in MikroBasic for Automation in Pattern Based Manufacturing

Punit Anand,Anand M Sharan 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.11

In this work the microcontroller is programmed in MikroBasic where the pattern shape is first determined using Fast Fourier Transforms offline and then the Fourier Coefficients are embedded in the program to perform calculations online to obtain the desired pattern. The stepper motors are used for accurate manufacturing. The program shows that microcontrollers do have sufficient memory to incorporate complex programs for intricate shape production.

Outcomes of Vascular Resection and Reconstruction in Extremity Soft Tissue Sarcoma and Bone Tumors

Anand Chetan Shah,Vishnu Ramanujan,Krishna Muralidharan,Anand Raja 대한혈관외과학회 2021 Vascular Specialist International Vol.37 No.1

Purpose: This study aimed to evaluate and analyze the feasibility and the oncological and functional outcomes of limb salvage surgery in extremity soft tissue sarcomas (ESTS) and bone tumors invading vessels. Materials and Methods: This single-center retrospective analysis included patients with ESTS encasing or invading major blood vessels that were treated by limb salvage surgery with vascular resection and reconstruction between January 1995 and December 2019. Patients with contiguous involvement of major blood vessels and nerves and patients requiring amputation were excluded from the study. Results: A total of 24 vessels (14 arteries and 10 veins) in 14 patients were reconstructed. Ten (71.4%) patients underwent both arterial and venous reconstruction, and four (28.6%) underwent only arterial reconstruction. Reconstruction was performed with a reversed saphenous vein (RSV) graft in 12 patients and with a synthetic graft (SG) in the other 12 patients. At a median follow-up of 27 months, RSV grafts were patent in 10 of 12 (83.3%) vessels and SGs were patent in 6 of 12 (50.0%) vessels (log-rank test, P=0.083). Out of 14 arteries and 10 veins, 11 arteries and 5 veins were patent, respectively. No patient developed local recurrence, and 2 (14.3%) patients developed distant metastases. Limb salvage rate was 13/14 (92.9%). The mean Musculoskeletal Tumor Society score was 83.3%. The 5- and 10-year overall survival rates were 80% and 50%, respectively. Conclusion: Limb salvage surgery in ESTS with vascular resection and reconstruction is feasible and provides favorable oncological and functional outcomes.

Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study

Ashish Anand,Ajoy Prasad Shetty,K. R. Renjith,Sri Vijay Anand K. S.,Rishi Mugesh Kanna,Shanmuganathan Rajasekaran 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.1

Study Design: Case-control study. Purpose: Sarcopenia is an age associated condition characterized by decrease in muscle mass, strength, and physical performance. We aimed to investigate whether sarcopenia increased the risk of vertebral fragility fractures among the elderly. Overview of Literature: Initial reports on sarcopenia suggest its contribution to the development of vertebral fragility fractures. However, recent studies showed contradictory findings. Methods: Fifty-one consecutive patients with vertebral fragility fractures and matched controls without fractures were evaluated for sarcopenia, T-score, body mass index, and presence of preexisting vertebral fractures. Sarcopenia was diagnosed as total psoas cross-sectional area (TPA) 2 standard deviations below normative value from normal young adults and decreased handgrip strength (26 kg for men and 18 kg for women). Univariate and multivariate analyses were performed using the fresh fracture occurrence as the dependent variable. Results: Sarcopenia was confirmed in 29.4% and 7.8% of cases and controls (p=0.005), respectively; 56.8% and 13.7% of cases and controls had previous vertebral fractures. Sarcopenia prevalence was greater among those with previous fractures (38% vs. 7.6%; odds ratio, 7.76; p<0.001). TPA was lower among the cases (1,278 mm2 vs. 1,569 mm2, p=0.001) and those with previous fractures (1,168 mm2 vs. 1,563 mm2, p<0.001). Handgrip strength was greater among those without previous fractures (19.6 kg vs. 16.3 kg, p=0.05). In multivariate analysis, sarcopenia was not identified as a significant predictor of fresh fractures whereas previous fractures and lower T-score were found to be significant. Conclusions: Sarcopenia is not an independent risk factor for fresh vertebral fragility fractures in the elderly.

Comparative Molecular Field Analysis of Pyrrolopyrimidines as LRRK2 Kinase Inhibitors

Anand Balupuri, Pavithra K. Balasubramanian, Seung Joo Cho 조선대학교 기초과학연구원 2016 조선자연과학논문집 Vol.9 No.1

Leucine rich repeat kinase 2 (LRRK2) is a highly promising target for Parkinson’s disease (PD) that affects millions of people worldwide. A three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis was performed on a series of pyrrolopyrimidine-based selective LRRK2 kinase inhibitors. This study was performed to rationalize the structural requirements responsible for the inhibitory activity of these compounds. A reliable 3D-QSAR model was developed using comparative molecular field analysis (CoMFA) technique. The model produced statistically acceptable results with a cross-validated correlation coefficient (q2) of 0.539 and a non-cross- validated correlation coefficient (r2) of 0.871. Robustness of the model was further evaluated by bootstrapping and progressive scrambling analysis. This work could assist in designing more potent LRRK2 inhibitors.

In silico study on indole derivatives as anti HIV-1 agents: a combined docking, molecular dynamics and 3D-QSAR study

Anand Balupuri,GADHECHANGDEV GORAKSHNATH,Pavithra K. Balasubramanian,Gugan Kothandan,조승주 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8

The HIV-1 envelope glycoprotein gp120 playsa vital role in the entry of virus into the host cells and is apotential antiviral drug target. Recently, indole derivativeshave been reported to inhibit HIV-1 through binding togp120, and this prevents gp120 and CD4 interaction toinhibit the infectivity of HIV-1. In this work, moleculardocking, molecular dynamics (MD) and three-dimensionalquantitative structure–activity relationship studies werecarried out. Molecular docking studies of the most activeand the least active compounds were performed to identifyimportant residues in the binding pocket. We refined thedocked poses by MD simulations which resulted in conformationalchanges. After equilibration, the structure ofthe ligand and receptor complex was stable. Therefore, wejust took the last snapshot as the representative bindingpose for this study. This pose for the most active inhibitorwas used as a template for receptor-based alignment whichwas subsequently used for comparative molecular fieldanalysis. Resultant 3D contour maps suggested smaller substituents are desirable at the 7-position of indole ring toavoid steric interactions with Ser375, Phe382 and Tyr384residues in the active site. These results can be exploited todevelop potential leads and for structure-based drug designof novel HIV-1 inhibitors.

A Comprehensive Review of BeagleBone Technology: Smart Board Powered by ARM

Anand Nayyar,Vikram Puri 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.4

In the last few years, there have been a rapid increase towards single-board microcontrollers. These days, trend has shifted towards development of full-fledged credit-card sized computer’s like Arduino Mega2560, Raspberry Pi, Orange Pi, Chip and even Beaglebone. These boards are low cost, low power, easy deployable and has user-friendly configurable options. Beaglebone technology is speeding up and growing like anything as millions of pieces are sold worldwide till date. Beaglebone boards are showing tremendous increase in adaptability and implementation in diverse areas like Robotics, Drones, Smart Homes, IoT devices, Linux and Cloud Computing Servers and even more. The aim and objective of this research paper is to provide a comprehensive review of Beaglebone Technology, various Beaglebone boards available till date with their technical specifications along with various research areas which can enable researchers and industry professionals to take up Beaglebone Technology and develop wide range of ready to use efficient and low cost products.

Ultrasound assisted synthesis of epoxidized sunflower oil and application as plasticizer

Anand P. Chavan,Parag R. Gogate 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.21 No.1

The effect of ultrasonic reactors on the epoxidation of sunflower oil was investigated using two differentsonochemical reactors such as ultrasonic horn and ultrasonic bath. The optimized parameters for thesynthesis were established followed by scale up studies. Use of combination of ultrasonic bath andmechanical agitation gavemaximum conversion to oxirane oxygen as 91.1%. The synthesized epoxidizedsunflower oil (ESNO) was used as plasticizer in polyvinyl chloride sheets and the performance wasevaluated by thermogravimetric analysis and mechanical testing methods. It has been established thatESNO plasticizer has ability to replace dioctyl phthalate (DOP) giving a sustainable and greener approach.

An Automatic Detection of Sleep using Different Statistical Parameters of Single Channel EEG Signals

Anand Prakash,Vandana Roy 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.10

The present work deals with the automatic detection of the sleep stages from the single-channel EEG data. Various stages of sleep are Awake, sleep stage 1, 2, 3 and 4 and rapid eye movement. Statistical attributes are extracted with the help of Ensemble Empirical Mode Decomposition, Hjorth parameter and zero-crossing rate. Ten-cross fold classification process is followed after best ranked attribute selection. After attributes are selected, the data is classified using bagging classifier. Accuracies of 98.46%, 95.62%, 93.87%, 93.17% and 91.93% for two-stages, three-stages, four-stages, five-stages and six-stages classification respectively. This classifier can be used for the real life application due to higher accuracies.

Substance over form-Malaysia

Anand Raj 한국국제조세협회 2016 조세학술논집 Vol.32 No.2