현대정당의 중앙집권성과 당수(黨首)의 지도성 : 영국의 이대정당을 중심으로

이재환 단국대학교 법학연구소 1967 법학논총 Vol.8 No.1

응급실에 내원한 상부위장관 정맥류 출혈 환자에서 표준진료지침의 적용이 환자의 예후 및 응급실 체류시간에 미치는 영향

이재환,유제성,박고은,박주영,정성필,공태영,범진호,고동률 대한응급의학회 2021 대한응급의학회지 Vol.32 No.5

Objective: Endoscopic hemostasis is a key treatment for variceal upper gastrointestinal bleeding. However, the effects of early endoscopy in variceal upper gastrointestinal bleeding have not been sufficiently studied. This study investigated the effects of the use of the critical pathway (CP) for upper gastrointestinal bleeding. Methods: The study was designed as a ‘before and after’ study. A group of patients diagnosed with variceal upper gastrointestinal bleeding from January 1, 2011, to December 31, 2014, and CP activated patients from January 1, 2015, to December 31, 2018, were reviewed retrospectively. The study endpoints included an analysis of the following in the two groups: time from emergency department (ED) arrival to endoscopy, number of blood transfusions, hospitalization period, intensive care unit (ICU) admission, 30-day mortality. Results: From January 1, 2011, to December 31, 2018, 207 patients were admitted with variceal upper gastrointestinal bleeding, and 137 patients with a Blatchford score of 7 or higher were included in the study. Of these, 88 patients visited before the implementation of CP and 49 patients visited thereafter. The time from ED arrival to endoscopy was 218.1± 201.7 minutes in the CP activated group, which was about 200 minutes shorter (P=0.046) than the non-CP group. There was no statistical difference in 30-day mortality, transfusion, emergency room hospitalization time, number of ICU admissions, and hospitalization days (P=0.348, P=0.394, P=0.651, P=0.164, and P=0.069). Conclusion: After CP, the time to endoscopy was significantly shortened, but it did not reduce mortality.

신라 동궁 출토 14면체 酒令 주사위의 명문해석과 그 의미

이재환 계명대학교 인문과학연구소 2018 동서인문학 Vol.0 No.54

Through the comparison with various drinking games of different eras in East Asia, I reinterpreted the meaning of the phrases from 14-sided dice used in drinking game excavated from East Palace of Silla Dynasty. I also identified the position of this dice in the genealogy of dices and drinking games of the world. The interpretation of the phrases on each side of the dice is as follows. Even if you got caught, just pass. Just pass instead of reciting a poem. Pass instead of making your face look ridiculous. If you have two cups of wine, you are exempted. If you have three cups of wine, remove one cup. If you are ugly, you cannot be exempted. If you bend your arms, you should drink everything. After drinking everything, you should make others laugh out loud. Let people hit your nose. Dance without any sound. Ask anyone to sing at will. Sing yourself a song called ‘恠来晩’. Sing yourself and drink yourself. Sing a song called ‘月鏡’. 이 논문은 동아시아 각 시대의 다양한 酒令들과의 비교·검토를 통해 신라 동궁출토 14면체 酒令 주사위의 令文을 다시 해석하고, 주사위과 酒令의 계보 속에서이 주사위가 차지하는 위치를 확인해 보았다. 해석한 令文의 내용은 다음과 같다. 걸린 것이 있어도 그냥 지나감, 그냥 詩만 읊고 지나감, 얼굴을 희롱하고 지나감, 두 잔이면 면제, 세 잔이면 한 잔 제거, 醜物은 면제 불가, 팔 굽히면 다 마심, 다 마시고 크게 웃기기, 여러 사람이 코 때리기, 소리 없이 춤추기, 마음대로 노래청하기, 스스로 「恠来晩」 부르기, 스스로 노래하고 스스로 마시기, 「月鏡」 한 곡.

타 장기종양에 의한 요관폐색에서 요관부목 유치의 성공률과 임상양상

이재환,박승철,서일영 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.1

Purpose: We assessed the success rate of internal ureteral stenting and the complications for patients with ureteral obstruction secondary to non-genitourinary malignancy. Materials and Methods: Between January 2001 and December 2005, ureteral stenting were attempted in 62 patients with ureteral obstruction secondary to non-genitourinary malignancy. Their medical records were reviewed for the primary diagnosis, the symptoms, the degree of hydronephrosis, the location of obstruction, stent failure, the time period until stent replacement due to stent failure, the complications and the status at the last followup. Results: A total 62 patients underwent an attempt at retrograde ureteral stenting for malignant extrinsic obstruction. The mean patient age was 57.6 years(range: 32-84) and the mean follow-up was 12.6 months. 44 patients(71%) were women, and the most common cancer diagnoses were cervical cancer(19), rectal cancer(16) and stomach cancer(11). A total of 23 patients(37%) required immediate percutaneous nephrostomy(PCN) referral. A total of 14 patients experienced late failure and required PCN. A total of 39 patients underwent stent replacement at a mean interval of 3.5 months. Conclusions: At almost 1 year follow-up, stent failure due to extrinsic compression occurred in 55.7% of the patients(37 of 62). We should carefully monitor patient who undergo ureteral stenting for ongoing obstruction and complication. (Korean J Urol 2008;49:49-54) Purpose: We assessed the success rate of internal ureteral stenting and the complications for patients with ureteral obstruction secondary to non-genitourinary malignancy. Materials and Methods: Between January 2001 and December 2005, ureteral stenting were attempted in 62 patients with ureteral obstruction secondary to non-genitourinary malignancy. Their medical records were reviewed for the primary diagnosis, the symptoms, the degree of hydronephrosis, the location of obstruction, stent failure, the time period until stent replacement due to stent failure, the complications and the status at the last followup. Results: A total 62 patients underwent an attempt at retrograde ureteral stenting for malignant extrinsic obstruction. The mean patient age was 57.6 years(range: 32-84) and the mean follow-up was 12.6 months. 44 patients(71%) were women, and the most common cancer diagnoses were cervical cancer(19), rectal cancer(16) and stomach cancer(11). A total of 23 patients(37%) required immediate percutaneous nephrostomy(PCN) referral. A total of 14 patients experienced late failure and required PCN. A total of 39 patients underwent stent replacement at a mean interval of 3.5 months. Conclusions: At almost 1 year follow-up, stent failure due to extrinsic compression occurred in 55.7% of the patients(37 of 62). We should carefully monitor patient who undergo ureteral stenting for ongoing obstruction and complication. (Korean J Urol 2008;49:49-54)

Dimethoxycurcumin, a Structural Analogue of Curcumin, Induces Apoptosis in Human Renal Carcinoma Caki Cells Through the Production of Reactive Oxygen Species, the Release of Cytochrome c, and the Activation of Caspase-3

이재환,홍혜민,권동득,배현옥,정희종 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.12

Purpose: Curcumin (Cur) has been reported to induce apoptosis in human renal carcinoma Caki cells. Dimethoxycurcumin (DMC), one of several synthetic Cur analogues, has been reported to have increased metabolic stability over Cur. We determined whether DMC, like Cur, induces apoptosis in Caki cells and also compared the apoptosis-inducing activity of DMC with that of Cur. Materials and Methods: Caki cells were treated with DMC possessing four methoxy groups, Cur possessing two methoxy groups, or bis-demethoxycurcumin (BMC), which lacks a methoxy group. Cell viability was measured by using a methyltetrazolium assay. Flow cytometry and the caspase-3 activity assay were used to detect apoptosis. The release of cytochrome-c (Cyt c) was detected by Western blot analysis. The production of reactive oxygen species (ROS) was measured by flow cytometry. Results: DMC, Cur, and BMC reduced cell viability and induced apoptosis, but the potency varied; DMC was the most potent compound, followed by Cur and BMC. ROS production, Cyt c release, and caspase-3 activity were increased, again in the order DMC>Cur>BMC. N-Acetylcysteine, a potent antioxidant, inhibited ROS production, Cyt c release, caspase-3 activation, and apoptosis induction in DMC-treated cells. Conclusions: These results indicate that DMC, like the original form of Cur, may induce apoptosis in human renal carcinoma Caki cells through the production of ROS, the release of mitochondrial Cyt c, and the subsequent activation of caspase-3. In addition, DMC is more potent than Cur in the ability to induce apoptosis.

「자기기만의 종교경험과 구원」에 관한 토론문

이재환 한국문학과종교학회 2020 한국문학과종교학회 국제학술대회 Vol.2020 No.01

日本의 災害對策 : 阪神大地震을 中心으로

李在煥 韓日問題硏究所 1995 韓日問題硏究 Vol.3 No.-

Cryogenic Engineering Conference and International Cryogenic Materials Conference (CEC-ICMC23)

이재환 한국초전도저온학회 (구 한국초전도저온공학회) 2023 초전도와 저온공학 Vol.25 No.1

바로미2 쌀가루의 상용화를 위한 산패취 발생 기전 규명

이재환 한국산업식품공학회 2023 학술대회 및 심포지엄 Vol.2023 No.11

신세포암의 종양 크기에 따른 복강경 근치적 신적출술 결과

이재환,서일영,임정식 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.3

Purpose: Laparoscopic surgery has been generalized for the treatment of localized renal cell carcinoma(RCC). Recently, laparoscopic radical nephrectomy for an RCC over the pT2 stage has gained rapid momentum as an effective surgery for treatment. We evaluated the possibility of the use of laparoscopic surgery for a large RCC, using the surgical results according to tumor size. Materials and Methods: Between June 2003 and June 2007, a total of 46 patients that under underwent a laparoscopic radical nephrectomy for RCC were divided into three groups according to tumor size: group 1 (n=16, tumor size ≤4cm), group 2(n=15, tumor size 4cm<n≤7cm), and group 3(n=15, tumor size >7cm). The surgical outcomes and perioperative morbidities were evaluated retrospectively, and were compared for each group. Results: The transfusion rate for group 3 patients was higher than for the other groups(group 1: 0%, group 2: 13.3%, group 3: 26,7%). However, the mean operative time(group 1: 154.3 minutes, group 2: 158.4 minutes, group 3: 197.9 minutes), postoperative initiative time to ambulate(group 1: 1.88 days, group 2: 2.00 days, group 3: 1.87 days) postoperative initiative time to diet(group 1: 1.38 days, group 2: 1.53 days, group 3: 1.53 days), total hospital stay(group 1: 7.94 days, group 2: 8.47 days, group 3: 8.20 days) and complication rate(group 1: 12.5%, group 2: 13.3%, group 3: 13.3%) were similar for patients in the three groups. Pathological results indicated that all cases showed a renal cell carcinoma with a negative surgical margin. Conclusions: There were no differences in the operative and postoperative results of the performance of laparoscopic radical nephrectomy according to tumor size, except for the transfusion rate. If the use of the technique and experience accumulate, laparoscopic radical nephrectomy will be feasible for all localized RCC regardless of tumor size. (Korean J Urol 2008;49:203-207) Purpose: Laparoscopic surgery has been generalized for the treatment of localized renal cell carcinoma(RCC). Recently, laparoscopic radical nephrectomy for an RCC over the pT2 stage has gained rapid momentum as an effective surgery for treatment. We evaluated the possibility of the use of laparoscopic surgery for a large RCC, using the surgical results according to tumor size. Materials and Methods: Between June 2003 and June 2007, a total of 46 patients that under underwent a laparoscopic radical nephrectomy for RCC were divided into three groups according to tumor size: group 1 (n=16, tumor size ≤4cm), group 2(n=15, tumor size 4cm<n≤7cm), and group 3(n=15, tumor size >7cm). The surgical outcomes and perioperative morbidities were evaluated retrospectively, and were compared for each group. Results: The transfusion rate for group 3 patients was higher than for the other groups(group 1: 0%, group 2: 13.3%, group 3: 26,7%). However, the mean operative time(group 1: 154.3 minutes, group 2: 158.4 minutes, group 3: 197.9 minutes), postoperative initiative time to ambulate(group 1: 1.88 days, group 2: 2.00 days, group 3: 1.87 days) postoperative initiative time to diet(group 1: 1.38 days, group 2: 1.53 days, group 3: 1.53 days), total hospital stay(group 1: 7.94 days, group 2: 8.47 days, group 3: 8.20 days) and complication rate(group 1: 12.5%, group 2: 13.3%, group 3: 13.3%) were similar for patients in the three groups. Pathological results indicated that all cases showed a renal cell carcinoma with a negative surgical margin. Conclusions: There were no differences in the operative and postoperative results of the performance of laparoscopic radical nephrectomy according to tumor size, except for the transfusion rate. If the use of the technique and experience accumulate, laparoscopic radical nephrectomy will be feasible for all localized RCC regardless of tumor size. (Korean J Urol 2008;49:203-207)