학술발표회 초록 : ( 에너지 / 환경 (1) ) ; STELF 시스템 성능향상을 위한 동적설계에 관한 연구

최승훈,이세일,백일현,최홍규,최익수,전해수 ( S . H . Choi,S . I . Lee,H . K . Choi,I . H . Baek,I . S . Choi,H . S . Chun ) 한국화학공학회 1994 추계학술발표회 Vol.- No.-

ER 유체와 압전작동기를 이용한 엔진마운트의 모델링 및 제어

최승훈,최영태,최승복,Choi, Seung-Hoon,Choi, Young-Tai,Choi, Seung-Bok 대한기계학회 1996 大韓機械學會論文集A Vol.20 No.2

This paper presents a new prototype of an engine mount for a passenger vehicle featuring ER(elector-rheological) fluids and piezoactuators. Conventional rubber mounts and various types of passive or semi-active hydraulic engine mounts have their own functional aims on the limited frequency band in the board engine operating frequency range. However, the proposed engine mount covers all frequency range of the engine operation. A mathematical model of the proposed engine mount is derived using the bond graph method which is inherently domain, the ER fluid is activated upon imposing electric field for vibration isolation while the piezoactuator. Computer control electric fluid for the ER fluid H.inf. cotrol technique is adopted for the piezoactuator. Computer simulation is undertaken in order to demonstrate isolation efficiency of the engine mount over wide operating frequency range.

사상체질유형과 ACE(angiotensin converting enzyme) 유전자 Type(polymorphism)과의 상관관계

최승훈,임용빈,이준우,김홍열,강철훈,Choi, S.H.,Yim, Y.B.,Rhee, J.W.,Kim, H.Y.,Kang, C.H. 사상체질의학회 1998 사상체질의학회지 Vol.10 No.2

Sasang Constitutional Medicine focuses on the different constitutional manifestations of the individual's nature and emotions. The nature and emotions drive the ascending and descending of Qi in the body. And this dynamics of the Qi's ascent and descent shapes the different types of structures, functions and temperaments. Although Sasang Constitutional Medicine has many advantages, its diagnosis of the constitution still depends on the doctors' own idea and has no objective identification. So many doctors in Korea have been trying to solve this problem. Recently, there are several efforts to find out the relationship between genetic information and constitution. By the way, May, 1998 there is a astonishing report about the gene which determines the human performance, that is ACE(angiotensin converting enzyme). And it suggests that the I allele was associated with improved endurance performance. ACE has three genotype including II, ID and DD. "I" means insertion and "D" means deletion. We determined the type of the Sasang constitution with QSCCII questionaire and the one's ACE genotype with PCR of the 127 people and we discovered the relationship between the constitution and the ACE genotype. The result is as follow. Among 39 people who have the II genotype, 7(18%) belong to Taeum(Taiyin), 9(23.1%) belong to Soyang(Shaoyang) and 23(59%) belong to Soeum(Shaoyin). Among 62 people who have the ID genotype, 18(29%) belong to Taeum(Taiyin), 21(33.9%) belong to Soyang(Shaoyang) and 23(37.1%) belong to Soeum(Shaoyin). Among 26 people who have DD genotype, 11(42.3%) belong to Taeum(Taiyin), 4(15.4%) belong to Soyang(Shaoyang) and 11(42.3%) belong to Soeum(Shaoyin). This data indicates that there are implicable relationship between the Sasang constitution and ACE genotype. Especially people who have II genotype have much possibility to be a Soeum(Shaoyin) person (59%) and Soyang(Shaoyang) person have less possibility to have DD genotype (15.4%). With this conclusion, we suggest further study of relationship between the Sasang constitution and ACE genotype and we think that other polymorphism can be a candidate of the partner of Sasang constitution.

잠재적 미생물 농약으로서 다양한 식물성장 촉진 활성을 가진 siderophore 생산 세균의 분리와 특성

최승훈,유지연,박성진,박민주,이오미,손홍주,Choi, Seunghoon,Yoo, Ji-Yeon,Park, SungJin,Park, MinJoo,Lee, O-Mi,Son, Hong-Joo 한국환경과학회 2020 한국환경과학회지 Vol.29 No.9

To develop eco-friendly microbial inoculants, siderophore-producing bacteria were isolated and identified, and their production characteristics and plant growth-promoting abilities were investigated. A strain S21 was isolated from rhizosphere of Korean perilla (Perilla frutescens) and identified as Enterobacter amnigenus by phenotypic properties and 16S rRNA gene sequencing. The highest siderophore production was obtained in a medium containing 0.5% fructose, 0.1% urea, 0.5% K₂HPO₄ and 0.1% succinic acid. By using this improved medium, siderophore production increased by 2.5 times compared to that of basal medium. The strain S21 showed insoluble phosphate solubilizing, ammonification and antifungal activities, and also produced hydrolytic enzymes (protease and lipase), indoleacetic acid and 1-aminocyclopropane-1-carboxylate deaminase. Our data suggest that E. amnigenus S21 is a potential candidate that can be used as eco-friendly biocontrol agent and biofertilizer.

『황제내경(黃帝內經)』의 체질론(體質論)

최승훈,Choi, Seung-hoon 사상체질의학회 1998 사상체질의학회지 Vol.10 No.2

One's constitution is formed congenitally and is also acquired, and is relatively stable in its individually manifested function, structure and temperament. It has characteristics of universality, complexity, generality and continuity. It is also manifested in physiological responses and expresses pathologic tendencies including susceptibility. Attempts at understanding constitution has had a long history throughout the world. In Oriental Medicine, the constitution had been acknowledged from the "Huangdi Neijing", which has been a bible in Oriental Medicine for about two thousand years. In many aspects, the "Huangdi Neijing" provides the basis for both basic and practical fields. In order to derive the ideal structure from the "Huangdi Neijing" to Lee Je-ma's(Lee Jayma's) Sasang Constitutional ideas, which can strengthen the understanding of ideal core of Oriental Medicine's constitutional characteristics, the author launched his analysis of the constitutional understandings in the "Huangdi Neijing" as a first step and came to the following: 1. The constitutional understanding in the "Huangdi Neijing" was done both via the physiological responses to heat, pain and acupuncture treatment and the pathologic tendencies via body structure, strength, body heat, courage and obesity. 2. It was recognized that the constitution was formed congenitally and also acquired factors like living conditions including food customs, residents and geographical conditions were explained in detailed. 3. The constitutional typology was suggested both by the general and systematic criterion according to the Yin-yang and the Five phase theories and by single criterion such as obesity, courage and the response to acupuncture treatment. 4. As diagnosis is related to the constitution, courage was adopted for the disease caused by emotions, obesity was for its manifestations of qi and blood, the quantities of qi-blood and Yin-yang in the typology by the Yin-yang and Five phase theories were suggested. 5. In the case of obesity, Yin-yang and Five phase theory, treatment according to the constitutional ideas was mentioned, and their goals were concluded as "being the balancing between Yin and Yang" which means the Yin-yang theory is more practical than the Five phase theory in Oriental Constitutional Medical field. According to the above understandings, the author would like to suggest that the constitutional ideas in the "Huangdi Neijing" based on the Yin-yang theory blossomed via the practical spirit of Zhang Zhong-jing's "Shanghanlun" and at last from Lee Je-ma's(Lee Jayma's) Sasang Constitutional Medicine which realized "the balancing between Yin and yang" through the practical applications of herbal treatments.

신생혈관 억제제 KJ3, Betulinic acid, Fumagillin의 혈관형성억제 및 신경모세포종에 대한 치료효과

최승훈,이정희,황의호,Choi, Seung-Hoon,Lee, Jung-Hee,Hwang, Eui-Ho 대한소아외과학회 2002 소아외과 Vol.8 No.2

The antiangiogenic effects of novel agent KJ3, Betulinic acid, and Fumagillin on the neovascularization were studied by examining ultrastructural alterations in the vasculature of synthetic gelform and mouse neuroblastoma C1300. Small pieces of gelform with 0.4% agar were introduced subcutaneously (s.c.) in 7 week old male CH3/HeJ mice. After the $LD_{50}s$ were determined by FACS analysis, a third of $LD_{50}$ of three drugs were injected either locally or intraperitoneally every other day for 14 days. A/J mice were inoculated s.c. with the C1300 neuroblastoma cell line, then either saline or three drugs were injected in the same manner. The antiangiogenic effects of three drugs were studied by measuring the histologic changes in tumors, and immunostaining for CD34, VIII/vWF, CD105, and thymidine phosphorylase. In the drug treated groups, the number of vessels in gelform experiments and C1300 neuroblastoma experiments were lower than the corresponding values in the control. The histologic findings were significantly different in drug treated groups on day 7, but these were not significant on day 14. These results imply that antiangiogenic agents were effective when the tumor burden is minimal.

CRDI 방식 디젤기관에서 바이오디젤유 적용시 매연과 NOx의 동시저감에 관한 실험적 연구

최승훈,오영택,Choi, Seung-Hun,Oh, Young-Taig 한국자동차공학회 2007 한국 자동차공학회논문집 Vol.15 No.3

Our environment is faced with serious problems related to the air pollution from automobiles in these days. In particular, the exhaust emissions of diesel engine are recognized main cause which influenced environment strong, In this study, the potential possibility of biodiesel fuel was investigated as an alternative fuel for a naturally aspirated common rail diesel engine. The smoke emission of biodiesel fuel 5vol-%(min. content) was reduced in comparison with diesel fuel, that is, it was reduced approximately 60% at 4000rpm, full load. But, power, torque and brake specific energy consumption didn't have no large differences. But, NOx emission of biodiesel fuel was increased compared with a commercial diesel fuel. Also, the effects of exhaust gas recirculation(EGR) on the characteristics of NOx emission has been investigated. It was found that simultaneous reduction of smoke and NOx was achieved with biodiesel fuel(5vol-%) and cooled EGR method($5{\sim}10%$) in a common rail diesel engine.

Hirschsprung's Diease: 수술 후 치료와 문제점

최승훈,Choi, Seung-Hoon 대한소아외과학회 2002 소아외과 Vol.8 No.1

Since Swenson and Bill established the treatment principles of Hirshsprung's disease in 1948, there have been significant advances in the management of this disease. During the last decade, one-stage correction of Hirshsprung's disease without colostomy and primary laparoscopic pull-through procedure became popular with recent advances in the technology and refinement of the equipments. But the outcomes for Hirshsprung's disease are not always successful, and long-term follow-up isessential. Most children after corrective surgery show significant improvement in respect to fecal continence and constipation, that may not be apparent until late adolescence. The purpose of this study was to review the postoperative problems of Hirschsprung's disease and it's management.

소아악성고형종의 진단에 있어서 chimeric transcript의 유용성

최승훈,Choi, Seung-Hoon 대한소아외과학회 1999 소아외과 Vol.5 No.1

Pediatric solid tumors have many histologic similarity. These tumors contained small round cell types, and cause frequent diagnostic problems in pediatric pathology. An important advance in the differentiation of these small round cell tumors has been the identification of consistent chromosomal translocations associated with several types of tumors. Eighteen patients with soft tissue sarcoma were available for review. Seventeen cell lines were also included in this study. The RNA from the specimens were analyzed by reverse transcriptase-polymerase chain reaction (RT-PCR). PAX3-FKHR fusion was present in four of five alveolar rhabdomyosarcoma and PAX7-FKHR fusion was detected in one of five alveolar rhabdomyosarcoma. None of the specimens expressed more than one chimeric transcript. EWS-FLI1 or EWS-ERG fusions were detected in all seven Ewings' sarcoma. No specimens showed EWS-WT1 fusion. These results corresponded well to the histopathologic diagnosis. There were no differences in the histologic appearances of tumors with the more frequent PAX3-FKHR or EWS-FLI1 fusions compared with those containing the variant PAX7-FKHR or EWS-ERG fusions. RT-PCR assay for chimeric transcript is a useful tool for rapid and objective diagnosis of pediatric solid tumors. Through these tools, we can approach genetically to the differential diagnosis of undifferentiated small round tumors.

저온소결 8/65/35 PLZT 세라믹의 전기열량 효과

최승훈,라철민,류주현,Choi, Seung-Hun,Ra, Cheol-Min,Yooa, Ju-Hyun 한국전기전자재료학회 2015 전기전자재료학회논문지 Vol.28 No.10

In this study, in order to develop the composition ceramics with the excellent electrocaloric properties, 8/65/35 PLZT ceramics were fabricated by the conventional solid-state method with the addition of $Bi_2O_3$, CuO, $Li_2CO_3$ and the variation of sintering temperature from $930^{\circ}C$ to $990^{\circ}C$. The XRD pattern of all specimens indicated general perovskite structure and the rhombohedral phase were observed. Curie temperature ($T_c$) of all specimens was observed in the vicinity of about $190^{\circ}C$. Density, coercive field and remnant polarization of the specimen sintered at $950^{\circ}C$ was $7.55g/cm^3$, 8.895 kV/cm, $11.22{\mu}C/cm^2$, respectively. EC effect of PLZT ceramics was measured by indirect method and the temperature change ${\Delta}T$ due to the electrocaloric effect was calculated by Maxwell's relations. ${\Delta}T$ of ceramic sintered at $950^{\circ}C$ was $0.21^{\circ}C$ under application of 40 kV/cm at $190^{\circ}C$.