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차승훈,신성욱,박석돈,오연균 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.2
Congenital hypohidrotic ectodermal dysplasia is a rare genodermatosis. It is characterized by hypohidrosis hypotrichosis, dental hypoplasia and characterstic facial features, which reflect a wide constellation of developmental defec of tissue from the ectoderm. We have encountered three cases of congenital hypohidrotic ectodermal dysplasia in a 28-year-old female, her new-born baby, and a 10-month-old boy with a family history. All of the three patients had hypohidrosis, hypotrichosis, defective dentition, and characterstic facial features, which were characterstic features of this disorder. In addition, they showed dry skin, sparse and thin hairs. Histopathologic findings of previous cases revealed no eccrine gland structure in the dermis with routine and immunohistochemical stainning such cytokeratin and filaggrin. We report three typical cases of hypohidrotic ectodermal dysplasia with the review of literature.
차승훈,정상원,박석돈 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.1
Background: Erythema multiforme (EM) is an acute self-limited disease with distinctive skin lesion. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been regarded as variants of EM within continuous spectrum. The reports that EM with mucous membrane involvement and SJS are clinically different disorders prompt us to investigate the relationship between clinical features and causative factors of these dermatoses. Methods: A retrospective clinico-histopathologic study was performed in 59 patients from 1988 to 1996. Results: While most of EM patients showed typical target, raised atypical target, or flat atypical target, purpura with or without blistering was noted in 80% of SJS patients and all of TEN patients. In EM patients, the skin eruption was mainly located acrally or centrally, diffuse involvement was observed in all of TEN patient. The involved skin surface area was wider in SJS and TEN than EM. Through the review of histopathologic slides, we found that 74% (17/23) was inflammatory type which was diagnosed as EM in 76% patients. Drug was the most common causative factor (41%), and there were the clinical evidences of recurrent herpes simplex virus infection in 12% (7/59) patients. Conclusion: We conclude that there is no difference in clinical features of EM, SJS, and TEN compared with reported studies. A detailed and precise prospective study is necessary to elucidate the clinical features and etiology of these unique dermatoses.
Griseofulvin 내복과 면역요법(DNCB, DPCP)을 병용한 편평 사마귀의 치료
차승훈,정상원,박석돈 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.3
Background : Although several kinds of treatment methods(destructive therapy, immunotherapy, etc) for plane warts have been attempted but there have been no enkirely satisfactory treatments, because the plane wants are seen to recur frequently. Objective : This study was aimed to evaluate the combination therapy of griseofuivin and immunotherapy(dinitrochlorobenzene=DNCB, diphenylcycloprope none=DPCP) on plane warts. Method : Sixteen patients(age range, 9 to 41 ; mean age, 21.8 years) with VPJ were treated with the combination therapy with griseofulvin(SOOmgJday) and single contact immunotherapy(DNCB or DPCP) Results : The mean treatment period of combination therapy was 4.6 weeks. The mean treatment period according to gender was 4.8 weeks in males and 4.4 weeks in females. The mean treatment periods according to the dwation of lesions were 5.4 weeks in less than 6 months(5 of 14 patients) and 3.2 weeks in over 6 months(9 of 14 patients). The mean treatment periods according to immunotherapy(DNCB or DPCP) were 3.4 weeks in 10 out of 11 patients by DNCB and 7.7 weeks in 4 out of 5 patients by DPCP. One patient developed acute urticaria by DNCB. Conclusion : We recommend a combination therapy with griseofulvin and immunotherapy(DNCB) as a treatment for plane warts because it is safe, noninvasive and cosmetically acceptable.
환경 다큐멘터리 서사 분석을 통한 미세먼지 현상에 관한 비판적 고찰
차승훈,장지혜,최근원,조재희 한국언론정보학회 2022 한국언론정보학보 Vol.114 No.-
Focusing on the “Particulate Matter(PM)” issue, which has had a huge impact on South Korean society and the public since the 2010s and has begun to emerge as a significant social problem, this study analyzed and examined environmental TV documentary texts on what social meaning and reproduction of it. Particulate matter is most closely related to human life among air pollutants. As particulate matter threatened humans and society, the media consistently paid attention to it. To this end, this study selected environmental documentaries from among television documentary texts as a study target and captured the story development method and in-depth meaning of the particulate matter narrative using structuralist narrative analysis. As a result of the study, first, it was found that the two environmental TV documentaries, which differ in timing, say differently by dividing the cause of particulate matter into intrinsic factors centered on South Korea and external factors represented by China. Second, in the two texts dealing with the same topic, ‘fine dust’, but with different broadcast times, it was found that factors such as time and the COVID-19 situation were influencing the narrative development. Finally, ideologies such as technology determinism and consumerism for coping with fine dust were found to be located in the depths of the text. This study will be meaningful in that it broadens the academic horizon by applying semiotic and critical perspectives that have rarely been dealt with in environmental communication.